JP2015502979A5 - - Google Patents

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JP2015502979A5
JP2015502979A5 JP2014548785A JP2014548785A JP2015502979A5 JP 2015502979 A5 JP2015502979 A5 JP 2015502979A5 JP 2014548785 A JP2014548785 A JP 2014548785A JP 2014548785 A JP2014548785 A JP 2014548785A JP 2015502979 A5 JP2015502979 A5 JP 2015502979A5
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alkyl
hydrogen
substituted
tautomer
salt
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JP2015502979A (ja
JP6113185B2 (ja
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Priority claimed from PCT/US2012/000586 external-priority patent/WO2013095684A1/en
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JP2014548785A 2011-12-22 2012-12-21 テロメラーゼ基質およびテロメア長作用因子としてのグアニンアナログ Active JP6113185B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161579575P 2011-12-22 2011-12-22
US61/579,575 2011-12-22
PCT/US2012/000586 WO2013095684A1 (en) 2011-12-22 2012-12-21 Guanine analogs as telomerase substrates and telomere length affectors

Related Child Applications (1)

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JP2016251548A Division JP2017081961A (ja) 2011-12-22 2016-12-26 テロメラーゼ基質およびテロメア長作用因子としてのグアニンアナログ

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JP2015502979A JP2015502979A (ja) 2015-01-29
JP2015502979A5 true JP2015502979A5 (https=) 2016-02-18
JP6113185B2 JP6113185B2 (ja) 2017-04-12

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JP2014548785A Active JP6113185B2 (ja) 2011-12-22 2012-12-21 テロメラーゼ基質およびテロメア長作用因子としてのグアニンアナログ
JP2016251548A Pending JP2017081961A (ja) 2011-12-22 2016-12-26 テロメラーゼ基質およびテロメア長作用因子としてのグアニンアナログ

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US (5) US9593137B2 (https=)
EP (2) EP3578563B1 (https=)
JP (2) JP6113185B2 (https=)
CA (1) CA2857490C (https=)
DK (2) DK3578563T3 (https=)
ES (2) ES2874774T3 (https=)
WO (1) WO2013095684A1 (https=)

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US9375485B2 (en) 2012-12-07 2016-06-28 Geron Corporation Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms
KR102163611B1 (ko) 2015-08-10 2020-10-08 머크 샤프 앤드 돔 코포레이션 항바이러스 베타-아미노산 에스테르 포스포디아미드 화합물
EP3386512B1 (en) 2015-12-10 2023-11-22 Merck Sharp & Dohme LLC Antiviral phosphodiamide prodrugs of tenofovir
EP3390413B1 (en) 2015-12-15 2020-08-19 Merck Sharp & Dohme Corp. Antiviral oxime phosphoramide compounds
US10736908B2 (en) 2016-10-26 2020-08-11 Merck Sharp & Dohme Corp. Antiviral aryl-amide phosphodiamide compounds
US11123355B2 (en) 2016-12-22 2021-09-21 Idenix Pharmaceuticals Llc Antiviral benzyl-amine phosphodiamide compounds
TWI820984B (zh) 2017-01-31 2023-11-01 美商基利科學股份有限公司 替諾福韋埃拉酚胺(tenofovir alafenamide)之晶型
KR102867725B1 (ko) 2017-07-28 2025-10-13 제론 코포레이션 골수형성이상 증후군의 치료 방법
US11826375B2 (en) 2018-07-19 2023-11-28 Merck Sharp & Dohme Llc Phosphinic amide prodrugs of tenofovir
UA130012C2 (uk) 2018-11-29 2025-10-15 Джерон Корпорейшн Спосіб лікування мієлодиспластичного синдрому
CN111205326B (zh) * 2020-02-13 2020-09-22 南京道尔医药科技有限公司 一种绿色环保的泰诺福韦制备方法
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