JP2015502177A5 - - Google Patents
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- JP2015502177A5 JP2015502177A5 JP2014549157A JP2014549157A JP2015502177A5 JP 2015502177 A5 JP2015502177 A5 JP 2015502177A5 JP 2014549157 A JP2014549157 A JP 2014549157A JP 2014549157 A JP2014549157 A JP 2014549157A JP 2015502177 A5 JP2015502177 A5 JP 2015502177A5
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- Japan
- Prior art keywords
- human
- human animal
- gene segments
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- immunoglobulin
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161578097P | 2011-12-20 | 2011-12-20 | |
| US61/578,097 | 2011-12-20 | ||
| PCT/US2012/069981 WO2013096142A1 (en) | 2011-12-20 | 2012-12-17 | Humanized light chain mice |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016240915A Division JP2017046722A (ja) | 2011-12-20 | 2016-12-13 | ヒト化軽鎖マウス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015502177A JP2015502177A (ja) | 2015-01-22 |
| JP2015502177A5 true JP2015502177A5 (cg-RX-API-DMAC7.html) | 2016-02-12 |
| JP6327750B2 JP6327750B2 (ja) | 2018-05-23 |
Family
ID=47501484
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014549157A Active JP6327750B2 (ja) | 2011-12-20 | 2012-12-17 | ヒト化軽鎖マウス |
| JP2016240915A Withdrawn JP2017046722A (ja) | 2011-12-20 | 2016-12-13 | ヒト化軽鎖マウス |
| JP2018215387A Active JP6728308B2 (ja) | 2011-12-20 | 2018-11-16 | ヒト化軽鎖マウス |
| JP2020113809A Active JP7152447B2 (ja) | 2011-12-20 | 2020-07-01 | ヒト化軽鎖マウス |
| JP2022156704A Active JP7507823B2 (ja) | 2011-12-20 | 2022-09-29 | ヒト化軽鎖マウス |
| JP2024098071A Pending JP2024113207A (ja) | 2011-12-20 | 2024-06-18 | ヒト化軽鎖マウス |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016240915A Withdrawn JP2017046722A (ja) | 2011-12-20 | 2016-12-13 | ヒト化軽鎖マウス |
| JP2018215387A Active JP6728308B2 (ja) | 2011-12-20 | 2018-11-16 | ヒト化軽鎖マウス |
| JP2020113809A Active JP7152447B2 (ja) | 2011-12-20 | 2020-07-01 | ヒト化軽鎖マウス |
| JP2022156704A Active JP7507823B2 (ja) | 2011-12-20 | 2022-09-29 | ヒト化軽鎖マウス |
| JP2024098071A Pending JP2024113207A (ja) | 2011-12-20 | 2024-06-18 | ヒト化軽鎖マウス |
Country Status (28)
Families Citing this family (74)
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| NO2792236T3 (cg-RX-API-DMAC7.html) | 2009-07-08 | 2018-04-14 | ||
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| US10662256B2 (en) | 2010-07-26 | 2020-05-26 | Trianni, Inc. | Transgenic mammals and methods of use thereof |
| DK2597945T3 (da) | 2010-07-26 | 2020-09-21 | Trianni Inc | Transgene dyr og fremgangsmåder til anvendelse deraf |
| RS55495B1 (sr) | 2010-08-02 | 2017-04-28 | Regeneron Pharma | Miševi koji stvaraju vezujuće proteine koji sadrže vl domene |
| ES2946169T3 (es) | 2011-02-25 | 2023-07-13 | Regeneron Pharma | Ratones ADAM6 |
| IL273982B2 (en) | 2011-08-05 | 2023-03-01 | Regeneron Pharma | Humanized mice possess a universal light chain |
| EP3741862A1 (en) | 2011-09-19 | 2020-11-25 | Kymab Limited | Animals, repertoires & methods for the production of human antibodies |
| EP2758535B1 (en) | 2011-09-19 | 2016-11-09 | Kymab Limited | Antibodies, variable domains&chains tailored for human use |
| EP2761008A1 (en) | 2011-09-26 | 2014-08-06 | Kymab Limited | Chimaeric surrogate light chains (slc) comprising human vpreb |
| KR20250021626A (ko) * | 2011-10-17 | 2025-02-13 | 리제너론 파마슈티칼스 인코포레이티드 | 제한된 면역글로불린 중쇄 마우스 |
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| JP2024500399A (ja) | 2020-12-16 | 2024-01-09 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | ヒト化Ｆｃアルファ受容体を発現するマウス |
| JP7579462B2 (ja) | 2021-04-20 | 2024-11-07 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | アルテミンに対するヒト抗体及びその使用方法 |
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| CN121039163A (zh) | 2023-05-02 | 2025-11-28 | 瑞泽恩制药公司 | 抗人m-钙粘蛋白（cdh15）抗体、缀合物及其用于将遗传有效负载递送至肌肉细胞的用途 |
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