JP2015212284A5 - - Google Patents
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- Publication number
- JP2015212284A5 JP2015212284A5 JP2015130074A JP2015130074A JP2015212284A5 JP 2015212284 A5 JP2015212284 A5 JP 2015212284A5 JP 2015130074 A JP2015130074 A JP 2015130074A JP 2015130074 A JP2015130074 A JP 2015130074A JP 2015212284 A5 JP2015212284 A5 JP 2015212284A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- peptide
- fusion protein
- chimeric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000037865 fusion proteins Human genes 0.000 claims 101
- 108020001507 fusion proteins Proteins 0.000 claims 101
- 108090000765 processed proteins & peptides Proteins 0.000 claims 86
- 229920001184 polypeptide Polymers 0.000 claims 30
- 102000004196 processed proteins & peptides Human genes 0.000 claims 30
- 241000605862 Porphyromonas gingivalis Species 0.000 claims 19
- 125000000539 amino acid group Chemical group 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 4
- 125000000729 N-terminal amino-acid group Chemical group 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 210000003527 eukaryotic cell Anatomy 0.000 claims 2
- 210000001236 prokaryotic cell Anatomy 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 1
- 229960001212 bacterial vaccine Drugs 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 229960004854 viral vaccine Drugs 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2008904476 | 2008-08-29 | ||
| AU2008904476A AU2008904476A0 (en) | 2008-08-29 | Prevention, treatment and diagnosis of P.gingivalis infection | |
| AU2008905483 | 2008-10-23 | ||
| AU2008905483A AU2008905483A0 (en) | 2008-10-23 | Prevention, treatment and diagnosis of P.gingivalis infection | |
| US15113209P | 2009-02-09 | 2009-02-09 | |
| US61/151,132 | 2009-02-09 | ||
| AU2009903052 | 2009-06-30 | ||
| AU2009903052A AU2009903052A0 (en) | 2009-06-30 | Prevention, treatment and diagnosis of P.gingivalis infection |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011524135A Division JP2012500633A (ja) | 2008-08-29 | 2009-08-28 | ポルフィロモナス・ジンジバリス感染の予防、治療及び診断 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015212284A JP2015212284A (ja) | 2015-11-26 |
| JP2015212284A5 true JP2015212284A5 (enExample) | 2016-01-28 |
| JP6235533B2 JP6235533B2 (ja) | 2017-11-22 |
Family
ID=41720713
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011524135A Pending JP2012500633A (ja) | 2008-08-29 | 2009-08-28 | ポルフィロモナス・ジンジバリス感染の予防、治療及び診断 |
| JP2015130074A Active JP6235533B2 (ja) | 2008-08-29 | 2015-06-29 | ポルフィロモナス・ジンジバリス感染の予防、治療及び診断 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011524135A Pending JP2012500633A (ja) | 2008-08-29 | 2009-08-28 | ポルフィロモナス・ジンジバリス感染の予防、治療及び診断 |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US8871213B2 (enExample) |
| EP (2) | EP2328914B1 (enExample) |
| JP (2) | JP2012500633A (enExample) |
| KR (1) | KR101721904B1 (enExample) |
| CN (2) | CN102203121A (enExample) |
| AU (1) | AU2009287340B2 (enExample) |
| BR (1) | BRPI0917321A2 (enExample) |
| CA (1) | CA2735171C (enExample) |
| DK (1) | DK2328914T3 (enExample) |
| ES (1) | ES2633738T3 (enExample) |
| IL (1) | IL211394B (enExample) |
| MX (1) | MX2011001949A (enExample) |
| MY (1) | MY178905A (enExample) |
| NZ (2) | NZ591612A (enExample) |
| PL (1) | PL2328914T3 (enExample) |
| RU (1) | RU2535898C2 (enExample) |
| TW (1) | TWI473626B (enExample) |
| WO (1) | WO2010022463A1 (enExample) |
| ZA (1) | ZA201101814B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO652897A0 (en) | 1997-04-30 | 1997-05-29 | University Of Melbourne, The | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
| US8129500B2 (en) | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
| US20100092471A1 (en) | 2006-06-27 | 2010-04-15 | Oral Health Australia Pty Ltd | Porphyromonas Gingivalis Polypeptides Useful in the Prevention of Periodontal Disease |
| DK2175851T3 (da) | 2007-07-12 | 2013-07-15 | Oral Health Australia Pty Ltd | Biofilmbehandling |
| WO2010022463A1 (en) * | 2008-08-29 | 2010-03-04 | Oral Health Australia Pty Ltd | Prevention, treatment and diagnosis of p.gingivalis infection |
| US8140041B2 (en) * | 2009-08-27 | 2012-03-20 | Mediatek Inc. | Tunable capacitive device with linearization technique employed therein |
| JP6310631B2 (ja) * | 2011-10-18 | 2018-04-11 | サンスター株式会社 | 歯周病原菌血漿または血清抗体価検査キット |
| WO2016061264A1 (en) * | 2014-10-14 | 2016-04-21 | The Forsyth Institute | Conjugates for delivery to mitochondria |
| CN110272472B (zh) * | 2019-07-18 | 2020-09-15 | 河南科技大学 | 一种抗牙龈卟啉单胞菌及具核酸杆菌多肽及应用 |
| CN111172177B (zh) * | 2019-07-30 | 2023-08-08 | 镇江市江澜绿洲生物技术有限公司 | cra4S1基因及其编码的蛋白和应用 |
| RU2714506C1 (ru) * | 2019-10-03 | 2020-02-18 | федеральное государственное бюджетное образовательное учреждение высшего образования "Приволжский исследовательский медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО "ПИМУ" Минздрава России) | Способ оценки эффективности лечения хронического катарального гингивита у детей |
| US20220226454A1 (en) * | 2021-01-11 | 2022-07-21 | Keystone Bio, Inc. | Antigenic composition(s) and method(s) of use against porphyromonas gingivalis for the prevention and/or treatment of infection and/or diseases |
| CA3225141A1 (en) * | 2021-07-13 | 2023-01-19 | Keystone Bio, Inc. | Diagnostics for porphyromonas gingivalis |
| CN116474096A (zh) * | 2022-01-14 | 2023-07-25 | 中山大学附属口腔医院 | 靶向牙龈卟啉单胞菌RgpB在结直肠癌的治疗及预防中的应用 |
| AU2023209364A1 (en) * | 2022-01-20 | 2024-08-01 | Denteric Pty Ltd | Chimeric polypeptides |
| KR20240149404A (ko) * | 2022-01-20 | 2024-10-14 | 덴테릭 피티와이 엘티디 | 키메라 폴리펩티드 |
| EP4466013A1 (en) * | 2022-01-20 | 2024-11-27 | Denteric Pty Ltd | Chimeric polypeptides |
| AR133317A1 (es) * | 2023-07-19 | 2025-09-17 | Sanofi Sa | Constructos antigénicos de porphyromonas gingivalis |
| WO2025019900A1 (en) * | 2023-07-26 | 2025-01-30 | Denteric Pty Ltd | Chimeric protein vaccine |
| WO2025019901A1 (en) * | 2023-07-26 | 2025-01-30 | Denteric Pty Ltd | Rna vaccines |
| WO2025019903A1 (en) * | 2023-07-26 | 2025-01-30 | Denteric Pty Ltd | Rna vaccines for use in animal health |
| WO2025019902A1 (en) * | 2023-07-26 | 2025-01-30 | Denteric Pty Ltd | Methods of treatment |
| CN120157758B (zh) * | 2025-03-26 | 2025-12-05 | 河南大学 | 牙龈卟啉单胞菌FimA单克隆抗体及其应用 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4837151A (en) | 1980-05-19 | 1989-06-06 | The Board Of Trustees Of The Leland Stanford Junior University, Stanford University | Live vaccines comprising two mutations and foreign antigen |
| US5210035A (en) | 1980-05-19 | 1993-05-11 | Board Of Trustees Of Leland Stanford Jr. University | Non-reventing live vaccines |
| US4735801A (en) | 1982-09-07 | 1988-04-05 | Board Of Trustees Of Leland Stanford Jr. University | Novel non-reverting salmonella live vaccines |
| US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| US5830710A (en) * | 1988-09-08 | 1998-11-03 | University Of Florida | Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease |
| AU6983594A (en) | 1993-06-28 | 1995-01-17 | Lion Corporation | Composition for oral cavity |
| US5523390A (en) | 1993-09-10 | 1996-06-04 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase |
| US5475097A (en) | 1993-10-21 | 1995-12-12 | University Of Georgia Research Foundation, Inc. | Lysine-specific Porphyromonas gingivalis proteinase |
| EP0717747B1 (en) | 1993-09-10 | 2003-06-04 | The University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase coding sequences |
| US6017532A (en) | 1993-09-10 | 2000-01-25 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase |
| JPH0797395A (ja) | 1993-09-28 | 1995-04-11 | Kyowa Medex Co Ltd | ポルフイロモナス・ジンジバリス線毛蛋白質の配列を含有するペプチド類及びその用途 |
| DE69527514T2 (de) | 1994-03-29 | 2003-04-03 | Kyowa Hakko Kogyo Co., Ltd. | Gen eines zelloberflächenpolypeptids |
| AUPN627595A0 (en) | 1995-10-30 | 1995-11-23 | University Of Melbourne, The | Diagnostics and treatments of periodontal disease |
| AU742668B2 (en) | 1996-03-22 | 2002-01-10 | Morehouse School Of Medicine | Immunogenic compositions comprising porphyromonas gingivalis peptides and methods |
| AUPN901296A0 (en) | 1996-03-29 | 1996-04-26 | University Of Melbourne, The | Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis |
| US7341727B1 (en) | 1996-05-03 | 2008-03-11 | Emergent Product Development Gaithersburg Inc. | M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same |
| AUPO652897A0 (en) * | 1997-04-30 | 1997-05-29 | University Of Melbourne, The | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
| US8129500B2 (en) | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
| AUPP083997A0 (en) | 1997-12-10 | 1998-01-08 | Csl Limited | Porphyromonas gingivalis nucleotides |
| US6444799B1 (en) | 1997-12-31 | 2002-09-03 | Csl Limited | P. gingivalis polynucleotides and uses thereof |
| US6627193B1 (en) | 1999-01-13 | 2003-09-30 | University Of Georgia Research Foundation, Inc. | Methods and compositions for control of blood coagulation |
| AUPP893999A0 (en) | 1999-03-01 | 1999-03-25 | Csl Limited | Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis |
| CA2373447A1 (en) | 1999-05-12 | 2000-11-16 | The General Hospital Corporation | Permeabilizing biofilms |
| GB9913437D0 (en) | 1999-06-09 | 1999-08-11 | Medical Res Council | Fusion proteins |
| AUPQ485999A0 (en) * | 1999-12-24 | 2000-02-03 | Csl Limited | P. gingivalis antigenic composition |
| CA2395610A1 (en) * | 1999-12-30 | 2001-07-12 | University Of Louisville Research Foundation, Inc. | Methods and compositions for inhibiting adhesion by microorganisms |
| AUPQ718200A0 (en) | 2000-04-28 | 2000-05-25 | Csl Limited | Porphyromonas gingivalis recombinant proteins and truncations |
| US6726898B2 (en) | 2000-11-17 | 2004-04-27 | Gary R. Jernberg | Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease |
| US20030083287A1 (en) | 2000-11-30 | 2003-05-01 | Burgess Nicola A. | ginS |
| AUPR575401A0 (en) | 2001-06-18 | 2001-07-12 | Unisearch Limited | Method of causing sloughing |
| JP2003192616A (ja) | 2001-12-27 | 2003-07-09 | Univ Nihon | 歯周病用dnaワクチン |
| JP2003286191A (ja) | 2002-03-27 | 2003-10-07 | Univ Nihon | 歯周病用粘膜免疫ワクチン |
| WO2004083425A1 (ja) | 2003-03-17 | 2004-09-30 | Kirin Beer Kabushiki Kaisha | 歯周病治療剤 |
| CA2535799A1 (en) * | 2003-08-15 | 2005-03-03 | University Of Florida | Identification of porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases |
| ZA200605660B (en) * | 2003-12-19 | 2007-11-28 | Univ Melbourne | Antimicrobial composition |
| EP1721283B1 (en) | 2004-02-06 | 2022-11-30 | Council of Scientific and Industrial Research | Computational method for identifying adhesin and adhesin-like proteins of therapeutic potential |
| US20070098649A1 (en) | 2004-03-22 | 2007-05-03 | The Board Of Trustees Of The University Of Illinois | Method and composition for controlling oral pathogens |
| GB0411150D0 (en) | 2004-05-19 | 2004-06-23 | Queen Mary & Westfield College | Vaccine |
| WO2006032104A1 (en) * | 2004-09-23 | 2006-03-30 | The University Of Melbourne | Antigenic complex for the diagnosis and treatment of porphyromonas gingivalis infection |
| US20060121031A1 (en) * | 2004-12-07 | 2006-06-08 | Mckenzie Brent S | Relay vaccine |
| ES2399345T3 (es) * | 2005-06-07 | 2013-03-27 | The University Of Melbourne | Mineralización dental |
| WO2008016385A2 (en) * | 2006-01-20 | 2008-02-07 | The University Of Washington | Deacylase polypeptides, deacylase polynucleotides, and methods of use thereof |
| US20100092471A1 (en) * | 2006-06-27 | 2010-04-15 | Oral Health Australia Pty Ltd | Porphyromonas Gingivalis Polypeptides Useful in the Prevention of Periodontal Disease |
| EP2402437B1 (en) * | 2006-07-05 | 2016-06-01 | Catalyst Biosciences, Inc. | Protease screening methods and proteases identified thereby |
| WO2008124646A2 (en) | 2007-04-06 | 2008-10-16 | The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services | Use of amyloid proteins as vaccine scaffolds |
| DK2175851T3 (da) * | 2007-07-12 | 2013-07-15 | Oral Health Australia Pty Ltd | Biofilmbehandling |
| JP2010532766A (ja) * | 2007-07-12 | 2010-10-14 | オーラル ヘルス オーストラリア ピーティーワイ リミテッド | バイオフィルムに対する免疫学的治療 |
| WO2010022463A1 (en) * | 2008-08-29 | 2010-03-04 | Oral Health Australia Pty Ltd | Prevention, treatment and diagnosis of p.gingivalis infection |
| BR112012002429A2 (pt) | 2009-08-02 | 2016-11-08 | Sanofi Pasteur Ltd | polipeptídeos de porphyromonas gingivalis |
| MY163512A (en) * | 2009-09-03 | 2017-09-15 | Pfizer Vaccines Llc | Pcsk9 vaccine |
| WO2011103932A1 (en) * | 2010-02-25 | 2011-09-01 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg | A process for the preparation of substituted prolyl peptides and similar peptidomimetics |
| MY162557A (en) * | 2010-02-26 | 2017-06-15 | Oral Health Australia Pty Ltd | Treatment or prevention of infection |
| ES2702534T3 (es) | 2010-12-15 | 2019-03-01 | Sunstar Inc | Kit de prueba para la titulación de anticuerpos en plasma o suero contra bacterias que causan enfermedades periodontales |
| DE102011003604A1 (de) | 2011-02-03 | 2012-08-09 | Battenfeld-Cincinnati Germany Gmbh | Kühlvorrichtung und Kühlverfahren |
| JP6310631B2 (ja) | 2011-10-18 | 2018-04-11 | サンスター株式会社 | 歯周病原菌血漿または血清抗体価検査キット |
| US20160347829A1 (en) * | 2015-05-27 | 2016-12-01 | Merial Inc. | Compositions containing antimicrobial IgY antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (OHC) microorganisms |
| EP3387439B1 (en) * | 2015-12-09 | 2020-02-26 | H. Hoffnabb-La Roche Ag | Direct affinity measurement of human igg1 binding multimeric antigens |
| WO2017097918A1 (en) | 2015-12-09 | 2017-06-15 | F. Hoffmann-La Roche Ag | Method for determining the in vivo interaction mode |
| CN108038398B (zh) * | 2017-12-22 | 2021-03-23 | 珠海市君天电子科技有限公司 | 一种二维码解析能力测试方法、装置及电子设备 |
-
2009
- 2009-08-28 WO PCT/AU2009/001112 patent/WO2010022463A1/en not_active Ceased
- 2009-08-28 PL PL09809116T patent/PL2328914T3/pl unknown
- 2009-08-28 NZ NZ591612A patent/NZ591612A/xx not_active IP Right Cessation
- 2009-08-28 DK DK09809116.8T patent/DK2328914T3/en active
- 2009-08-28 CN CN2009801423053A patent/CN102203121A/zh active Pending
- 2009-08-28 AU AU2009287340A patent/AU2009287340B2/en active Active
- 2009-08-28 MY MYPI2011000894A patent/MY178905A/en unknown
- 2009-08-28 CN CN201710494699.5A patent/CN107266582B/zh active Active
- 2009-08-28 TW TW98129181A patent/TWI473626B/zh not_active IP Right Cessation
- 2009-08-28 RU RU2011108943/10A patent/RU2535898C2/ru not_active IP Right Cessation
- 2009-08-28 JP JP2011524135A patent/JP2012500633A/ja active Pending
- 2009-08-28 EP EP09809116.8A patent/EP2328914B1/en active Active
- 2009-08-28 US US13/060,653 patent/US8871213B2/en active Active
- 2009-08-28 CA CA2735171A patent/CA2735171C/en active Active
- 2009-08-28 BR BRPI0917321A patent/BRPI0917321A2/pt not_active Application Discontinuation
- 2009-08-28 EP EP17169952.3A patent/EP3255057B1/en active Active
- 2009-08-28 MX MX2011001949A patent/MX2011001949A/es active IP Right Grant
- 2009-08-28 NZ NZ598834A patent/NZ598834A/xx not_active IP Right Cessation
- 2009-08-28 KR KR1020117006990A patent/KR101721904B1/ko active Active
- 2009-08-28 ES ES09809116.8T patent/ES2633738T3/es active Active
-
2011
- 2011-02-24 IL IL211394A patent/IL211394B/en active IP Right Grant
- 2011-03-09 ZA ZA2011/01814A patent/ZA201101814B/en unknown
-
2014
- 2014-09-16 US US14/487,461 patent/US9518109B2/en active Active
-
2015
- 2015-06-29 JP JP2015130074A patent/JP6235533B2/ja active Active
-
2016
- 2016-12-06 US US15/370,144 patent/US20170247420A1/en not_active Abandoned
-
2018
- 2018-09-18 US US16/134,721 patent/US10851138B2/en active Active
-
2020
- 2020-11-13 US US17/098,021 patent/US11572391B2/en active Active
-
2023
- 2023-01-09 US US18/151,675 patent/US20230374081A1/en not_active Abandoned
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