DK1660524T3 - Identifikation af porphyromonas gingivalis virulens polynukleotider til diagnose, behandling, og monitorering af periodontale sygdomme - Google Patents

Identifikation af porphyromonas gingivalis virulens polynukleotider til diagnose, behandling, og monitorering af periodontale sygdomme

Info

Publication number
DK1660524T3
DK1660524T3 DK04780587.4T DK04780587T DK1660524T3 DK 1660524 T3 DK1660524 T3 DK 1660524T3 DK 04780587 T DK04780587 T DK 04780587T DK 1660524 T3 DK1660524 T3 DK 1660524T3
Authority
DK
Denmark
Prior art keywords
treatment
diagnosis
identification
monitoring
periodontal disease
Prior art date
Application number
DK04780587.4T
Other languages
English (en)
Inventor
Ann Progulske-Fox
Jeffrey Daniel Hillman
Martin Handfield
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Application granted granted Critical
Publication of DK1660524T3 publication Critical patent/DK1660524T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
DK04780587.4T 2003-08-15 2004-08-10 Identifikation af porphyromonas gingivalis virulens polynukleotider til diagnose, behandling, og monitorering af periodontale sygdomme DK1660524T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49558903P 2003-08-15 2003-08-15
PCT/US2004/025778 WO2005019249A2 (en) 2003-08-15 2004-08-10 Identification of porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases

Publications (1)

Publication Number Publication Date
DK1660524T3 true DK1660524T3 (da) 2011-05-09

Family

ID=36084060

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04780587.4T DK1660524T3 (da) 2003-08-15 2004-08-10 Identifikation af porphyromonas gingivalis virulens polynukleotider til diagnose, behandling, og monitorering af periodontale sygdomme

Country Status (9)

Country Link
US (2) US7416852B2 (da)
EP (2) EP2426140A1 (da)
JP (1) JP2007529195A (da)
AT (1) ATE495189T1 (da)
AU (1) AU2004266213A1 (da)
CA (1) CA2535799A1 (da)
DE (1) DE602004031024D1 (da)
DK (1) DK1660524T3 (da)
WO (1) WO2005019249A2 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
US8129500B2 (en) 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
US7838259B2 (en) * 2005-02-01 2010-11-23 University Of Florida Research Foundation Genes of Porphyromonas gingivalis W83 involved in invasion of human cells
JP2009544279A (ja) 2006-06-27 2009-12-17 オーラル ヘルス オーストラリア ピーティーワイ リミテッド 歯周病の予防に有用なポルフィロモナス・ジンジバリスポリペプチド
EP2162150A4 (en) * 2007-06-22 2011-10-12 Univ Guelph VACCINE AGAINST CLOSTRIDIUM PERFRINGENS
AU2013203250B2 (en) * 2007-07-12 2014-11-13 Oral Health Australia Pty Ltd Immunology treatment for biofilms
WO2009006700A1 (en) * 2007-07-12 2009-01-15 Oral Health Australia Pty Ltd Immunology treatment for biofilms
NZ595252A (en) * 2007-07-12 2013-11-29 Oral Health Australia Pty Ltd Biofilm treatment
EP2328914B1 (en) 2008-08-29 2017-05-10 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of p.gingivalis infection
US8140041B2 (en) * 2009-08-27 2012-03-20 Mediatek Inc. Tunable capacitive device with linearization technique employed therein
AU2011214908A1 (en) * 2010-02-12 2012-09-20 Sydney West Area Health Services (Swahs) Protein domains and uses therefor
MY162557A (en) * 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
EP3139167B1 (en) 2010-12-15 2018-09-26 Sunstar Inc. Test kit for plasma or serum antibody titer against periodontal disease-causing bacteria
WO2012173244A1 (ja) * 2011-06-17 2012-12-20 国立大学法人東北大学 人獣共通感染性歯周病菌検出用マーカー
JP6310631B2 (ja) * 2011-10-18 2018-04-11 サンスター株式会社 歯周病原菌血漿または血清抗体価検査キット
GB201508860D0 (en) 2015-05-22 2015-07-01 Nat Univ Ireland Diagnostic method
WO2020069397A1 (en) * 2018-09-27 2020-04-02 Cortexyme, Inc. Methods for detection of microbial nucleic acids in body fluids
US10487331B1 (en) * 2018-11-30 2019-11-26 National Cheng Kung University Aptamers of surface proteins of periodontal pathogens and uses thereof

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366246A (en) 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4474893A (en) 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US5866136A (en) 1986-08-01 1999-02-02 Commonwealth Scientific And Industrial Organisation Recombinant vaccine
US5202238A (en) 1987-10-27 1993-04-13 Oncogen Production of chimeric antibodies by homologous recombination
ES2110444T3 (es) 1990-06-11 1998-02-16 Nexstar Pharmaceuticals Inc Ligandos de acidos nucleicos.
US5861254A (en) 1997-01-31 1999-01-19 Nexstar Pharmaceuticals, Inc. Flow cell SELEX
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US5496938A (en) 1990-06-11 1996-03-05 Nexstar Pharmaceuticals, Inc. Nucleic acid ligands to HIV-RT and HIV-1 rev
US5840867A (en) 1991-02-21 1998-11-24 Gilead Sciences, Inc. Aptamer analogs specific for biomolecules
US5756291A (en) 1992-08-21 1998-05-26 Gilead Sciences, Inc. Aptamers specific for biomolecules and methods of making
AR003125A1 (es) 1995-06-01 1998-07-08 Astra Ab Antigenos bacterianos para el diagnostico de infecciones con helicobacter pylori, una molecula de adn que lo codifica, un vector, una celula huesped,procedimiento para producir el polipeptido, composiciones para vacunas adecuadas para uso terapeutico y profilactico, el uso del polipeptido en la
US6583275B1 (en) * 1997-07-02 2003-06-24 Genome Therapeutics Corporation Nucleic acid sequences and expression system relating to Enterococcus faecium for diagnostics and therapeutics
US6617156B1 (en) * 1997-08-15 2003-09-09 Lynn A. Doucette-Stamm Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics
ES2419664T3 (es) * 1997-12-10 2013-08-21 Csl Limited Polipéptidos y polinucleótidos de Porphyromonas gingivalis
AU1922999A (en) 1997-12-16 1999-07-05 Baylor College Of Medicine Needle-free injection of formulated nucleic acid molecules
US6444799B1 (en) * 1997-12-31 2002-09-03 Csl Limited P. gingivalis polynucleotides and uses thereof
WO1999049890A1 (en) 1998-03-31 1999-10-07 Daewoong Pharmaceutical Co., Ltd. A preventive and therapeutic vaccine for helicobacter pylori-associated diseases
US6180348B1 (en) 1998-04-20 2001-01-30 Weihua Li Method of isolating target specific oligonucleotide ligands
EP1076694B1 (en) 1998-04-22 2006-03-08 Loma Linda University Methods and substances for preventing and treating autoimmune disease
WO2000053722A2 (en) 1999-03-10 2000-09-14 Phogen Limited Delivery of nucleic acids and proteins to cells
ES2184659T1 (es) 1999-08-06 2003-04-16 Ivigene Corp Polinucleotidos microbianos expresados durante la infeccion de un organismo hospedante.
FR2807446B1 (fr) * 2000-04-11 2005-05-06 Agronomique Inst Nat Rech Genomes de lactococcus lactis, polypeptides et utilisations
US7186528B2 (en) * 2000-06-15 2007-03-06 Smithkline Beecham Corporation Method for preparing a physiologically active IL-18 polypeptide
GB0107658D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
JP2005514025A (ja) * 2002-01-07 2005-05-19 ライフセンサーズ、インク. タンパク質発現及び精製のための方法及び組成

Also Published As

Publication number Publication date
US7416852B2 (en) 2008-08-26
US20080299591A1 (en) 2008-12-04
DE602004031024D1 (de) 2011-02-24
US20060078950A1 (en) 2006-04-13
WO2005019249A3 (en) 2005-09-15
CA2535799A1 (en) 2005-03-03
ATE495189T1 (de) 2011-01-15
EP2426140A1 (en) 2012-03-07
WO2005019249A2 (en) 2005-03-03
WO2005019249A8 (en) 2005-05-12
US8703436B2 (en) 2014-04-22
EP1660524A2 (en) 2006-05-31
JP2007529195A (ja) 2007-10-25
AU2004266213A1 (en) 2005-03-03
EP1660524B1 (en) 2011-01-12

Similar Documents

Publication Publication Date Title
DK1660524T3 (da) Identifikation af porphyromonas gingivalis virulens polynukleotider til diagnose, behandling, og monitorering af periodontale sygdomme
DE60314495D1 (de) Aminosäuresequenzen die die fähigkeit besitzen, die durchdringung durch eine biologische barriere erleichtern
BRPI0417543A (pt) quinolinas úteis no tratamento de doença cardiovascular
DK1287364T3 (da) Diagnostisk og terapi til makulære degenerationsrelaterede lidelser
EA200900802A1 (ru) Способы и композиции для лечения амилоидных заболеваний
BRPI0411743A (pt) método e composições para tratar doenças relacionadas a amilóides
WO2006059252A3 (en) Methods and fluorinated compositions for treating amyloid-related diseases
ATE462973T1 (de) Diagnose und prävention der krebszellinvasion
DK2211183T3 (da) Fremgangsmåde til diagnosticering og overvågning af Alzheimer's sygdom
DE60218493D1 (de) Substituierte 7-aza-ä2.2.1übicycloheptane für die behandlung von krankheiten
EA200701825A1 (ru) Вакцины против хламидиоза
NO20060230L (no) Nye aminobenzofenonforbindelser
DE602004019614D1 (de) Medizinische Vorrichtung für Endoskope
NO20062062L (no) Procsesser for preparering av forskjellige former for (S)-(+)-clopidogrel bisulfat
DE602004003952D1 (de) Substituierte tetrahydrobenzothienopyrimidinamine verbindungen geeignet zur behandlung von hyper-proliferative disorders
WO2006074450A3 (en) Methods and compositions for detecting and modulating periodontal disorders and periodontal diseases
ITUD20030118A1 (it) Dispositivo di sicurezza per macchine operatrici e metodo di riconoscimento della presenza di persone, utilizzante tale dispositivo di sicurezza.
NO20054346L (no) Sammensetninger og fremgangsmater for forebygging og behandling av endotoksinrelaterte sykdommer og tilstander
WO2006065273A3 (en) New human parvovirus
BR0318042B1 (pt) aparelho de identificaÇço.
ITMO20030254A1 (it) Impianto per la concentrazione del succo di pomodoro.
NO20053562L (no) Nye aminobenzofenonforbindelser
EP1766391A4 (en) NEW DIAGNOSTIC METHODS FOR THE TREATMENT OF P. AERUGINOSA INFECTIONS AND REAGENTS FOR THESE METHODS
DE60331654D1 (de) Nicht-radioaktives Strontiummittel zur Behandlung von Krebs
WO2007019888A3 (en) Therapeutic compositions containing mesalamine and a co-agent for treating colon diseases