WO2007019888A3 - Therapeutic compositions containing mesalamine and a co-agent for treating colon diseases - Google Patents

Therapeutic compositions containing mesalamine and a co-agent for treating colon diseases Download PDF

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Publication number
WO2007019888A3
WO2007019888A3 PCT/EP2006/002783 EP2006002783W WO2007019888A3 WO 2007019888 A3 WO2007019888 A3 WO 2007019888A3 EP 2006002783 W EP2006002783 W EP 2006002783W WO 2007019888 A3 WO2007019888 A3 WO 2007019888A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions containing
agent
therapeutic compositions
treating colon
containing mesalamine
Prior art date
Application number
PCT/EP2006/002783
Other languages
French (fr)
Other versions
WO2007019888A2 (en
Inventor
Soldato Piero Del
Original Assignee
Ctg Pharma S R L
Soldato Piero Del
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ctg Pharma S R L, Soldato Piero Del filed Critical Ctg Pharma S R L
Publication of WO2007019888A2 publication Critical patent/WO2007019888A2/en
Publication of WO2007019888A3 publication Critical patent/WO2007019888A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compositions containing mesalamine or its derivatives and a co-agent effective for the treatment of gastrointestinal altered motility, sensitivity and secretion and abdominal viscera disorders including both functional and organic diseases are useful for the treatment of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Furthermore the present invention provides formulations and methods for treating IBS and IBD.
PCT/EP2006/002783 2005-08-12 2006-03-27 Therapeutic compositions containing mesalamine and a co-agent for treating colon diseases WO2007019888A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05425598.9 2005-08-12
EP05425598 2005-08-12

Publications (2)

Publication Number Publication Date
WO2007019888A2 WO2007019888A2 (en) 2007-02-22
WO2007019888A3 true WO2007019888A3 (en) 2007-07-12

Family

ID=35431284

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/002783 WO2007019888A2 (en) 2005-08-12 2006-03-27 Therapeutic compositions containing mesalamine and a co-agent for treating colon diseases

Country Status (1)

Country Link
WO (1) WO2007019888A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2359812C (en) 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
CN105412126B (en) * 2015-10-28 2017-12-29 薛会光 Composition containing SASP and its application in treatment ulcerative colitis medicine is prepared
US20230248718A1 (en) * 2022-02-09 2023-08-10 Sushma Paul BERLIA Pharmaceutical combination of antispasmodic and anxiolytic agent

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0528076A1 (en) * 1991-08-20 1993-02-24 Duphar International Research B.V Use of Mebeverine against non-specific inflammatory bowel disease
WO1998047481A1 (en) * 1997-04-18 1998-10-29 Janssen Pharmaceutica N.V. Use of 5ht3 antagonists for promoting intestinal lavage
US20030114356A1 (en) * 2001-08-15 2003-06-19 Peter James Dunn Method of treating irritable bowel syndrome
US20040092511A1 (en) * 1999-12-10 2004-05-13 Billstein Stephan Anthony Pharmaceutical combinations and their use in treating gastrointestinal and abdominal viscera disorders
US20040229849A1 (en) * 2002-09-24 2004-11-18 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
WO2005048927A2 (en) * 2003-11-13 2005-06-02 Combinatorx, Incorporated Methods and reagents for the treatment of inflammatory disorders

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0528076A1 (en) * 1991-08-20 1993-02-24 Duphar International Research B.V Use of Mebeverine against non-specific inflammatory bowel disease
WO1998047481A1 (en) * 1997-04-18 1998-10-29 Janssen Pharmaceutica N.V. Use of 5ht3 antagonists for promoting intestinal lavage
US20040092511A1 (en) * 1999-12-10 2004-05-13 Billstein Stephan Anthony Pharmaceutical combinations and their use in treating gastrointestinal and abdominal viscera disorders
US20030114356A1 (en) * 2001-08-15 2003-06-19 Peter James Dunn Method of treating irritable bowel syndrome
US20040229849A1 (en) * 2002-09-24 2004-11-18 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
WO2005048927A2 (en) * 2003-11-13 2005-06-02 Combinatorx, Incorporated Methods and reagents for the treatment of inflammatory disorders

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
FREXINOS J ET AL: "EFFECT OF TRIMEBUTINE ON COLONIC MYOELECTRICAL ACTIVITY IN IBS PATIENTS", EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, SPRINGER VERLAG, DE, vol. 28, no. 2, 1985, pages 181 - 185, XP008037078, ISSN: 0031-6970 *
GRAUL A I: "Annual Update 2003: Gastrointestinal Drugs", DRUGS OF THE FUTURE 2003 SPAIN, vol. 28, no. 8, 2003, pages 797 - 821, XP008056894, ISSN: 0377-8282 *
KOUNTOURAS J ET AL: "EFFICACY OF TRIMEBUTINE THERAPY IN PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE AND IRRITABLE BOWEL SYNDROME", HEPATO-GASTROENTEROLOGY, THIEME, STUTTGART, DE, vol. 49, no. 43, January 2002 (2002-01-01), pages 193 - 197, XP009019408, ISSN: 0172-6390 *
LAURITSEN K ET AL: "CLINICAL PHARMACOKINETICS OF DRUGS USED IN THE TREATMENT OF GASTROINTESTINAL DISEASES (PART I)", CLINICAL PHARMACOKINETICS, LEA & FEBIGER, PHILADELPHIA, PA, US, vol. 19, no. 1, July 1990 (1990-07-01), pages 11 - 31, XP008023648 *
LAURITSEN K ET AL: "CLINICAL PHARMACOKINETICS OF DRUGS USED IN THE TREATMENT OF GASTROINTESTINAL DISEASES (PART II)", CLINICAL PHARMACOKINETICS, LEA & FEBIGER, PHILADELPHIA, PA, US, vol. 19, no. 2, 1990, pages 94 - 125, XP008057074 *
SEGARS L W ET AL: "Mesalamine and osalazine:5-Aminosalicylic acid agents for the treatment of inflammatory bowel disease", CLINICAL PHARMACY, AMERICAN SOCIETY OF HOSPITAL PHARMACISTS, US, vol. 11, June 1992 (1992-06-01), pages 514 - 528, XP002963310, ISSN: 0278-2677 *
TERHAAG B ET AL: "DIE MODIFIKATION DER ORO-CAECALEN TRANSITZEIT VON SALAZOSULFAPYRIDIN DURCH ATROPIN UND METOCLOPRAMID AM GESUNDEN PROBANDEN MODIFICATION OF OROCECAL TRANSIT TIME OF SALAZOPYRIN BY ATROPINE AND METOCLOPRAMIDE IN HEALTHY VOLUNTEERS", DEUTSCHE ZEITSCHRIFT FUER VERDAUUNGS- UND STOFFWECHSELKRANKHEITEN, BARTH, LEIPZIG, DE, vol. 46, no. 6, 1986, pages 327 - 332, XP008057004, ISSN: 0012-1053 *

Also Published As

Publication number Publication date
WO2007019888A2 (en) 2007-02-22

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