JP2014520874A - 組成物 - Google Patents

組成物 Download PDF

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Publication number
JP2014520874A
JP2014520874A JP2014520661A JP2014520661A JP2014520874A JP 2014520874 A JP2014520874 A JP 2014520874A JP 2014520661 A JP2014520661 A JP 2014520661A JP 2014520661 A JP2014520661 A JP 2014520661A JP 2014520874 A JP2014520874 A JP 2014520874A
Authority
JP
Japan
Prior art keywords
compound
nanogram
pharmaceutically acceptable
nanograms
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014520661A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014520874A5 (enExample
Inventor
ルイーズ アンベリー，クレア
デイビッド エドワーズ，クリストファー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
GlaxoSmithKline LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline LLC filed Critical GlaxoSmithKline LLC
Publication of JP2014520874A publication Critical patent/JP2014520874A/ja
Publication of JP2014520874A5 publication Critical patent/JP2014520874A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2014520661A 2011-07-22 2012-07-19 組成物 Pending JP2014520874A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161510624P 2011-07-22 2011-07-22
US61/510,624 2011-07-22
PCT/EP2012/064139 WO2013014052A1 (en) 2011-07-22 2012-07-19 Composition

Publications (2)

Publication Number Publication Date
JP2014520874A true JP2014520874A (ja) 2014-08-25
JP2014520874A5 JP2014520874A5 (enExample) 2015-08-06

Family

ID=46581948

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014520661A Pending JP2014520874A (ja) 2011-07-22 2012-07-19 組成物

Country Status (20)

Country Link
US (2) US10112946B2 (enExample)
EP (1) EP2734186B1 (enExample)
JP (1) JP2014520874A (enExample)
KR (1) KR101916928B1 (enExample)
CN (1) CN103841958A (enExample)
AU (2) AU2012289042A1 (enExample)
BR (1) BR112014001425A2 (enExample)
CA (1) CA2841361A1 (enExample)
CY (1) CY1120802T1 (enExample)
DK (1) DK2734186T3 (enExample)
ES (1) ES2693122T3 (enExample)
HR (1) HRP20181667T1 (enExample)
LT (1) LT2734186T (enExample)
PL (1) PL2734186T3 (enExample)
PT (1) PT2734186T (enExample)
RS (1) RS57995B1 (enExample)
RU (1) RU2631482C2 (enExample)
SI (1) SI2734186T1 (enExample)
SM (1) SMT201800642T1 (enExample)
WO (1) WO2013014052A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA103195C2 (uk) 2008-08-11 2013-09-25 Глаксосмитклайн Ллк Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
JP2014520874A (ja) 2011-07-22 2014-08-25 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 組成物
PE20150730A1 (es) 2012-08-24 2015-06-02 Glaxosmithkline Llc Compuestos de pirazolopirimidina
WO2014081645A1 (en) 2012-11-20 2014-05-30 Glaxosmithkline Llc Novel compounds
AU2013348216B2 (en) 2012-11-20 2016-10-13 Glaxosmithkline Llc Novel compounds
CA2890201A1 (en) 2012-11-20 2014-05-30 Glaxosmithkline Llc Novel compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010018133A1 (en) * 2008-08-11 2010-02-18 Smithkline Beecham Corporation Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases

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Also Published As

Publication number Publication date
DK2734186T3 (en) 2019-01-07
HRP20181667T1 (hr) 2018-12-14
LT2734186T (lt) 2018-12-10
ES2693122T3 (es) 2018-12-07
SMT201800642T1 (it) 2019-01-11
RU2631482C2 (ru) 2017-09-22
SI2734186T1 (sl) 2018-11-30
EP2734186B1 (en) 2018-09-12
KR101916928B1 (ko) 2018-11-08
AU2012289042A1 (en) 2014-03-13
BR112014001425A2 (pt) 2017-11-21
US20190023707A1 (en) 2019-01-24
PT2734186T (pt) 2018-12-17
CN103841958A (zh) 2014-06-04
WO2013014052A1 (en) 2013-01-31
KR20140049001A (ko) 2014-04-24
RS57995B1 (sr) 2019-01-31
EP2734186A1 (en) 2014-05-28
CA2841361A1 (en) 2013-01-31
US20140288099A1 (en) 2014-09-25
AU2016202513B2 (en) 2018-03-22
RU2013157398A (ru) 2015-08-27
US10112946B2 (en) 2018-10-30
PL2734186T3 (pl) 2019-01-31
CY1120802T1 (el) 2019-12-11

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