|
TW530047B
(en)
|
1994-06-08 |
2003-05-01 |
Pfizer |
Corticotropin releasing factor antagonists
|
|
US6403599B1
(en)
|
1995-11-08 |
2002-06-11 |
Pfizer Inc |
Corticotropin releasing factor antagonists
|
|
US7067664B1
(en)
|
1995-06-06 |
2006-06-27 |
Pfizer Inc. |
Corticotropin releasing factor antagonists
|
|
AU3176297A
(en)
|
1996-06-25 |
1998-01-14 |
Novartis Ag |
Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof
|
|
US5985848A
(en)
|
1997-10-14 |
1999-11-16 |
Albert Einstein College Of Medicine Of Yeshiva University |
Inhibitors of nucleoside metabolism
|
|
TW572758B
(en)
|
1997-12-22 |
2004-01-21 |
Sumitomo Pharma |
Type 2 helper T cell-selective immune response inhibitors comprising purine derivatives
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6232320B1
(en)
|
1998-06-04 |
2001-05-15 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
|
CZ27399A3
(cs)
|
1999-01-26 |
2000-08-16 |
Ústav Experimentální Botaniky Av Čr |
Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
|
|
US20030187261A1
(en)
|
2000-01-07 |
2003-10-02 |
Libor Havlicek |
Purine derivatives, process for their preparation and use thereof
|
|
US6627645B2
(en)
|
2000-04-28 |
2003-09-30 |
Acadia Pharmaceuticals, Inc. |
Muscarinic agonists
|
|
GB0114286D0
(en)
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
|
MXPA04001253A
(es)
*
|
2001-08-09 |
2004-06-03 |
Ono Pharmaceutical Co |
Derivados de acidos carboxilicos y agente farmaceutico que comprende los mismos como ingrediente activo.
|
|
TW200301251A
(en)
|
2001-12-20 |
2003-07-01 |
Wyeth Corp |
Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
|
|
RU2217159C1
(ru)
*
|
2002-03-18 |
2003-11-27 |
ООО "Содарм фарма" |
Раствор для ингаляций фармацевтической композиции глутовент и способ его терапевтического применения
|
|
DK1348707T3
(da)
|
2002-03-28 |
2010-12-13 |
Ustav Ex Botan Av Cr V V I Inst Of Ex Botany Academy Of Sciences Of The Czech Republic Pro |
Pyrazolo[4,3-d]pyrimidiner, fremgangsmåder til deres fremstilling samt deres terapeutiske anvendelse
|
|
CA2484921A1
(en)
|
2002-05-06 |
2003-11-13 |
Genelabs Technologies, Inc. |
Nucleoside derivatives for treating hepatitis c virus infection
|
|
US6713241B2
(en)
|
2002-08-09 |
2004-03-30 |
Eastman Kodak Company |
Thermally developable emulsions and imaging materials containing binder mixture
|
|
EP1539783B1
(en)
|
2002-08-21 |
2011-04-13 |
Albert Einstein College Of Medicine Of Yeshiva University |
Inhibitors of nucleoside phosphorylases and nucleosidases
|
|
US7754728B2
(en)
|
2002-09-27 |
2010-07-13 |
Dainippon Sumitomo Pharma Co., Ltd. |
Adenine compound and use thereof
|
|
US20060148805A1
(en)
|
2003-07-01 |
2006-07-06 |
Meng Hsin Chen |
Opthalmic compositions for treating ocular hypertension
|
|
US20070161582A1
(en)
|
2003-08-08 |
2007-07-12 |
Dusan Mijikovic |
Pharmaceutical compositions and methods for metabolic modulation
|
|
EA200600540A1
(ru)
|
2003-09-05 |
2006-08-25 |
Анадис Фармасьютикалз, Инк. |
Введение лигандов tlr7 и их пролекарств для лечения инфекции вируса гепатита с
|
|
CA2540598C
(en)
|
2003-10-03 |
2013-09-24 |
3M Innovative Properties Company |
Pyrazolopyridines and analogs thereof
|
|
EP1699512B1
(en)
|
2003-11-03 |
2012-06-20 |
Glaxo Group Limited |
A fluid dispensing device
|
|
US20070225303A1
(en)
|
2004-03-26 |
2007-09-27 |
Haruhisa Ogita |
8-Oxoadenine Compound
|
|
JP4472693B2
(ja)
|
2004-03-26 |
2010-06-02 |
大日本住友製薬株式会社 |
９置換−８−オキソアデニン化合物
|
|
BRPI0509576A
(pt)
|
2004-04-02 |
2007-05-29 |
Osi Pharm Inc |
composto, método de tratamento de um paciente tendo uma condição que é mediada pela atividade de proteìna quinase, e, composição farmacêutica
|
|
MXPA06013250A
(es)
|
2004-05-14 |
2007-02-28 |
Abbott Lab |
Inhibidores de quinasa como agentes terapeuticos.
|
|
US20060029642A1
(en)
|
2004-08-03 |
2006-02-09 |
Dusan Miljkovic |
Methods and compositions for improved chromium complexes
|
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
EP1888587A1
(en)
|
2005-05-04 |
2008-02-20 |
Pfizer Limited |
2-amido-6-amino-8-oxopurine derivatives as toll-like receptor modulators for the treatment of cancer and viral infections, such as hepatitis c
|
|
NZ540160A
(en)
|
2005-05-20 |
2008-03-28 |
Einstein Coll Med |
Inhibitors of nucleoside phosphorylases
|
|
US7932257B2
(en)
|
2005-07-22 |
2011-04-26 |
Sunesis Pharmaceuticals, Inc. |
Substituted pyrazolo[4,3-d]pyrimidines as aurora kinase inhibitors
|
|
CN101304748A
(zh)
|
2005-08-22 |
2008-11-12 |
加利福尼亚大学董事会 |
Tlr激动剂
|
|
BRPI0615307A2
(pt)
|
2005-08-25 |
2009-08-04 |
Schering Corp |
agonistas de adrenorreceptor alfa2c
|
|
US8003624B2
(en)
|
2005-08-25 |
2011-08-23 |
Schering Corporation |
Functionally selective ALPHA2C adrenoreceptor agonists
|
|
US20100152230A1
(en)
|
2005-09-02 |
2010-06-17 |
Pfizer Inc. |
Hydroxy substituted 1h-imidazopyridines and methods
|
|
TW200801003A
(en)
|
2005-09-16 |
2008-01-01 |
Astrazeneca Ab |
Novel compounds
|
|
TW200745114A
(en)
|
2005-09-22 |
2007-12-16 |
Astrazeneca Ab |
Novel compounds
|
|
JPWO2007034917A1
(ja)
|
2005-09-22 |
2009-03-26 |
大日本住友製薬株式会社 |
新規なアデニン化合物
|
|
WO2007034881A1
(ja)
|
2005-09-22 |
2007-03-29 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規アデニン化合物
|
|
US20090118263A1
(en)
|
2005-09-22 |
2009-05-07 |
Dainippon Sumitomo Pharma Co., Ltd. |
Novel Adenine Compound
|
|
WO2007034916A1
(ja)
|
2005-09-22 |
2007-03-29 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規アデニン化合物
|
|
EP1939199A4
(en)
|
2005-09-22 |
2010-10-20 |
Dainippon Sumitomo Pharma Co |
NEW ADENINE CONNECTION
|
|
CN1947717B
(zh)
|
2005-10-14 |
2012-09-26 |
卓敏 |
选择性抑制腺苷酸环化酶1的化合物在制备用于治疗神经性疼痛和炎性疼痛的药物中的应用
|
|
ES2374455T3
(es)
|
2006-02-17 |
2012-02-16 |
Pfizer Limited |
Derivados de 3-deazapurinza como moduladores de tlr7.
|
|
WO2007110868A2
(en)
|
2006-03-28 |
2007-10-04 |
Atir Holding S.A. |
Heterocyclic compounds and uses thereof in the treatment of sexual disorders
|
|
GB0610666D0
(en)
*
|
2006-05-30 |
2006-07-05 |
Glaxo Group Ltd |
Fluid dispenser
|
|
EP2700638A1
(en)
|
2006-05-31 |
2014-02-26 |
The Regents Of the University of California |
Purine analogs
|
|
WO2008004948A1
(en)
|
2006-07-05 |
2008-01-10 |
Astrazeneca Ab |
8-oxoadenine derivatives acting as modulators of tlr7
|
|
DK2038290T3
(da)
|
2006-07-07 |
2013-12-02 |
Gilead Sciences Inc |
Modulatorer af toll-lignende receptor 7
|
|
TW200831105A
(en)
|
2006-12-14 |
2008-08-01 |
Astrazeneca Ab |
Novel compounds
|
|
WO2008101867A1
(en)
|
2007-02-19 |
2008-08-28 |
Smithkline Beecham Corporation |
Purine derivatives as immunomodulators
|
|
ES2373616T3
(es)
|
2007-03-19 |
2012-02-07 |
Astrazeneca Ab |
Compuestos de 8-oxo-adenina 9 sustituidos como moduladores del receptor de tipo toll (tlr7).
|
|
ES2457316T3
(es)
|
2007-03-19 |
2014-04-25 |
Astrazeneca Ab |
Compuestos 8-oxo-adenina 9 sustituidos como moduladores del receptor similares a toll (TLR7)
|
|
JPWO2008114819A1
(ja)
|
2007-03-20 |
2010-07-08 |
大日本住友製薬株式会社 |
新規アデニン化合物
|
|
PE20081887A1
(es)
|
2007-03-20 |
2009-01-16 |
Dainippon Sumitomo Pharma Co |
Nuevo compuesto de adenina
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
MX2009013832A
(es)
|
2007-06-29 |
2010-03-10 |
Gilead Sciences Inc |
Derivados de purina y su uso como moduladores del receptor 7 similar a un puente.
|
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
AU2008287421A1
(en)
|
2007-08-10 |
2009-02-19 |
Glaxosmithkline Llc |
Nitrogen containing bicyclic chemical entities for treating viral infections
|
|
PE20091156A1
(es)
|
2007-12-17 |
2009-09-03 |
Astrazeneca Ab |
Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
|
|
WO2009151910A2
(en)
|
2008-05-25 |
2009-12-17 |
Wyeth |
Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer
|
|
US8946239B2
(en)
|
2008-07-10 |
2015-02-03 |
Duquesne University Of The Holy Spirit |
Substituted pyrrolo, -furano, and cyclopentylpyrimidines having antimitotic and/or antitumor activity and methods of use thereof
|
|
KR101649881B1
(ko)
*
|
2008-08-11 |
2016-08-30 |
글락소스미스클라인 엘엘씨 |
신규의 아데닌 유도체
|
|
JP5519670B2
(ja)
|
2008-08-11 |
2014-06-11 |
グラクソスミスクライン エルエルシー |
アレルギー性、炎症性及び感染性疾患治療用のプリン誘導体
|
|
UA103195C2
(uk)
|
2008-08-11 |
2013-09-25 |
Глаксосмитклайн Ллк |
Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
|
|
US8802684B2
(en)
|
2008-08-11 |
2014-08-12 |
Glaxosmithkline Llc |
Adenine derivatives
|
|
WO2010018132A1
(en)
|
2008-08-11 |
2010-02-18 |
Smithkline Beecham Corporation |
Compounds
|
|
WO2010018131A1
(en)
|
2008-08-11 |
2010-02-18 |
Smithkline Beecham Corporation |
Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
|
|
WO2010083725A1
(zh)
|
2009-01-20 |
2010-07-29 |
山东轩竹医药科技有限公司 |
含有取代的含氮稠杂环的头孢菌素衍生物
|
|
WO2010111406A2
(en)
*
|
2009-03-24 |
2010-09-30 |
Myriad Pharmaceuticals, Inc. |
Compounds and therapeutic uses thereof
|
|
CN102469790B
(zh)
|
2009-08-07 |
2014-12-03 |
葛兰素史密丝克莱恩生物有限公司 |
脂质化氧代腺嘌呤衍生物
|
|
ES2525826T3
(es)
|
2010-02-10 |
2014-12-30 |
Glaxosmithkline Llc |
Maleato de 6-amino-2-{[(1s)-1-metilbutil]-oxi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8H-purin-8-ona
|
|
WO2011098451A1
(en)
|
2010-02-10 |
2011-08-18 |
Glaxosmithkline Llc |
Purine derivatives and their pharmaceutical uses
|
|
WO2012009258A2
(en)
|
2010-07-13 |
2012-01-19 |
Edward Roberts |
Peptidomimetic galanin receptor modulators
|
|
WO2012092552A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
CA2825599C
(en)
|
2011-02-01 |
2021-07-13 |
The Board Of Trustees Of The University Of Illinois |
4-methyl-n-hydroxybenzamide compounds as histone deacetylase (hdac) inhibitors
|
|
EP2670244B1
(en)
|
2011-02-04 |
2018-04-11 |
Duquesne University of The Holy Spirit |
Bicyclic and tricyclic pyrimidine tyrosine kinase inhibitors with antitubulin activity and methods of treating a patient
|
|
PL2734186T3
(pl)
|
2011-07-22 |
2019-01-31 |
Glaxosmithkline Llc |
Kompozycja
|
|
SG11201500787YA
(en)
|
2012-08-24 |
2015-03-30 |
Glaxosmithkline Llc |
Pyrazolopyrimidine compounds
|
|
JP6228223B2
(ja)
|
2012-11-20 |
2017-11-08 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ |
新規化合物
|
|
ES2625023T3
(es)
|
2012-11-20 |
2017-07-18 |
Glaxosmithkline Llc |
Compuestos novedosos
|
|
US9550785B2
(en)
|
2012-11-20 |
2017-01-24 |
Glaxosmithkline Llc |
Pyrrolopyrimidines as therapeutic agents for the treatment of diseases
|
|
EP3107915B1
(en)
|
2014-02-20 |
2017-11-08 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Pyrrolo[3,2-d]pyrimidine derivatives as inducers of human interferon
|