|
TW530047B
(en)
|
1994-06-08 |
2003-05-01 |
Pfizer |
Corticotropin releasing factor antagonists
|
|
US7125880B1
(en)
|
1995-06-06 |
2006-10-24 |
Pfizer Inc. |
Corticotropin releasing factor antagonists
|
|
US6403599B1
(en)
|
1995-11-08 |
2002-06-11 |
Pfizer Inc |
Corticotropin releasing factor antagonists
|
|
AU3176297A
(en)
|
1996-06-25 |
1998-01-14 |
Novartis Ag |
Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof
|
|
US5985848A
(en)
|
1997-10-14 |
1999-11-16 |
Albert Einstein College Of Medicine Of Yeshiva University |
Inhibitors of nucleoside metabolism
|
|
TW572758B
(en)
|
1997-12-22 |
2004-01-21 |
Sumitomo Pharma |
Type 2 helper T cell-selective immune response inhibitors comprising purine derivatives
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6232320B1
(en)
|
1998-06-04 |
2001-05-15 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
|
CZ27399A3
(cs)
|
1999-01-26 |
2000-08-16 |
Ústav Experimentální Botaniky Av Čr |
Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
|
|
US20030187261A1
(en)
|
2000-01-07 |
2003-10-02 |
Libor Havlicek |
Purine derivatives, process for their preparation and use thereof
|
|
ATE290000T1
(de)
|
2000-04-28 |
2005-03-15 |
Acadia Pharm Inc |
Muscarinagonisten
|
|
GB0114286D0
(en)
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
|
RU2315746C2
(ru)
*
|
2001-08-09 |
2008-01-27 |
Оно Фармасьютикал Ко., Лтд. |
Производные карбоновых кислот и фармацевтическое средство, содержащее их в качестве активного ингредиента
|
|
TW200301251A
(en)
|
2001-12-20 |
2003-07-01 |
Wyeth Corp |
Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
|
|
RU2217159C1
(ru)
*
|
2002-03-18 |
2003-11-27 |
ООО "Содарм фарма" |
Раствор для ингаляций фармацевтической композиции глутовент и способ его терапевтического применения
|
|
EP1348707B1
(en)
|
2002-03-28 |
2010-08-25 |
Ustav Experimentalni Botaniky AV CR, v.v.i. (Institute of Experimental Botany Academy of Sciences of the Czech Republic, PRO) |
Pyrazolo[4,3-d]pyrimidines, processes for their preparation and methods for therapy
|
|
MXPA04010983A
(es)
|
2002-05-06 |
2005-02-14 |
Genelabs Tech Inc |
Derivados de nucleosidos para tratar infecciones por el virus de la hepatitis c.
|
|
US6713241B2
(en)
|
2002-08-09 |
2004-03-30 |
Eastman Kodak Company |
Thermally developable emulsions and imaging materials containing binder mixture
|
|
CA2496698C
(en)
|
2002-08-21 |
2012-01-24 |
Albert Einstein College Of Medicine Of Yeshiva University |
5-h-pyrrolo[3,2-d]pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases
|
|
CA2497765A1
(en)
|
2002-09-27 |
2004-04-08 |
Sumitomo Pharmaceuticals Co., Ltd. |
8-hydroxy substituted adenine compounds and uses thereof
|
|
CN1816530A
(zh)
|
2003-07-01 |
2006-08-09 |
麦克公司 |
用于治疗高眼压症的眼用组合物
|
|
WO2005020892A2
(en)
|
2003-08-08 |
2005-03-10 |
Mitochroma Research, Inc. |
Pharmaceutical compositions and methods for metabolic modulation
|
|
BRPI0414045A
(pt)
|
2003-09-05 |
2006-10-24 |
Anadys Pharmaceuticals Inc |
administração de ligantes de tlr7 e pró-medicamentos dos mesmos para tratamento de infecção por vìrus de hepatite c
|
|
NZ546274A
(en)
|
2003-10-03 |
2009-12-24 |
3M Innovative Properties Co |
Pyrazolopyridines and analags thereof
|
|
CA2544378A1
(en)
|
2003-11-03 |
2005-05-19 |
Glaxo Group Limited |
A fluid dispensing device
|
|
MXPA06011080A
(es)
|
2004-03-26 |
2007-04-16 |
Astrazeneca Ab |
Compuesto de 8-oxoadenina 9-sustituido.
|
|
WO2005092892A1
(ja)
|
2004-03-26 |
2005-10-06 |
Dainippon Sumitomo Pharma Co., Ltd. |
8−オキソアデニン化合物
|
|
PT1740591E
(pt)
|
2004-04-02 |
2009-09-24 |
Osi Pharm Inc |
Inibidores da proteína quinase heterobicíclicos em substituição de anel bicíclico 6,6
|
|
US20060074102A1
(en)
|
2004-05-14 |
2006-04-06 |
Kevin Cusack |
Kinase inhibitors as therapeutic agents
|
|
US20060029642A1
(en)
|
2004-08-03 |
2006-02-09 |
Dusan Miljkovic |
Methods and compositions for improved chromium complexes
|
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
BRPI0611435A2
(pt)
|
2005-05-04 |
2010-09-08 |
Pfizer Ltd |
derivados de 2-amido-6-amino-8-oxopurina, composições farmacêuticas, uso e processo de preparo dos mesmos
|
|
NZ540160A
(en)
|
2005-05-20 |
2008-03-28 |
Einstein Coll Med |
Inhibitors of nucleoside phosphorylases
|
|
AU2006272876A1
(en)
|
2005-07-22 |
2007-02-01 |
Sunesis Pharmaceuticals, Inc. |
Pyrazolo pyrimidines useful as aurora kinase inhibitors
|
|
WO2007024707A2
(en)
|
2005-08-22 |
2007-03-01 |
The Regents Of The University Of California |
Tlr agonists
|
|
PE20070336A1
(es)
|
2005-08-25 |
2007-04-16 |
Schering Corp |
Compuestos de indolina como agonistas de receptores adrenergicos alfa2c funcionalmente selectivos
|
|
US8003624B2
(en)
|
2005-08-25 |
2011-08-23 |
Schering Corporation |
Functionally selective ALPHA2C adrenoreceptor agonists
|
|
EP1924581A1
(en)
|
2005-09-02 |
2008-05-28 |
Pfizer, Inc. |
Hydroxy substituted 1h-imidazopyridines and methods
|
|
TW200801003A
(en)
|
2005-09-16 |
2008-01-01 |
Astrazeneca Ab |
Novel compounds
|
|
TW200745114A
(en)
|
2005-09-22 |
2007-12-16 |
Astrazeneca Ab |
Novel compounds
|
|
EP1939201A4
(en)
|
2005-09-22 |
2010-06-16 |
Dainippon Sumitomo Pharma Co |
NEW ADENINE CONNECTION
|
|
WO2007034817A1
(ja)
|
2005-09-22 |
2007-03-29 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規アデニン化合物
|
|
JPWO2007034881A1
(ja)
|
2005-09-22 |
2009-03-26 |
大日本住友製薬株式会社 |
新規アデニン化合物
|
|
WO2007034916A1
(ja)
|
2005-09-22 |
2007-03-29 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規アデニン化合物
|
|
WO2007034882A1
(ja)
|
2005-09-22 |
2007-03-29 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規アデニン化合物
|
|
CN1947717B
(zh)
|
2005-10-14 |
2012-09-26 |
卓敏 |
选择性抑制腺苷酸环化酶1的化合物在制备用于治疗神经性疼痛和炎性疼痛的药物中的应用
|
|
KR20080085232A
(ko)
|
2006-02-17 |
2008-09-23 |
화이자 리미티드 |
Tlr7 조절제로서 3-데아자퓨린 유도체
|
|
WO2007110868A2
(en)
|
2006-03-28 |
2007-10-04 |
Atir Holding S.A. |
Heterocyclic compounds and uses thereof in the treatment of sexual disorders
|
|
GB0610666D0
(en)
|
2006-05-30 |
2006-07-05 |
Glaxo Group Ltd |
Fluid dispenser
|
|
AU2007257423B8
(en)
|
2006-05-31 |
2012-02-16 |
The Regents Of The University Of California |
Purine analogs
|
|
EP2041135A4
(en)
|
2006-07-05 |
2010-12-01 |
Astrazeneca Ab |
As TLR7 MODULATORS, 8-OXOADENINE DERIVATIVES WORK
|
|
DK2038290T3
(da)
|
2006-07-07 |
2013-12-02 |
Gilead Sciences Inc |
Modulatorer af toll-lignende receptor 7
|
|
TW200831105A
(en)
|
2006-12-14 |
2008-08-01 |
Astrazeneca Ab |
Novel compounds
|
|
PT2125792E
(pt)
|
2007-02-19 |
2011-03-01 |
Glaxosmithkline Llc |
Derivados de purina como imunomoduladores
|
|
WO2008114006A1
(en)
|
2007-03-19 |
2008-09-25 |
Astrazeneca Ab |
9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
|
|
JP5480637B2
(ja)
|
2007-03-19 |
2014-04-23 |
アストラゼネカ・アクチエボラーグ |
Toll様受容体(tlr7)モジュレーターとしての9−置換−8−オキソ−アデニン化合物
|
|
US8044056B2
(en)
|
2007-03-20 |
2011-10-25 |
Dainippon Sumitomo Pharma Co., Ltd. |
Adenine compound
|
|
TW200902018A
(en)
|
2007-03-20 |
2009-01-16 |
Dainippon Sumitomo Pharma Co |
Novel adenine compound
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
NZ582090A
(en)
|
2007-06-29 |
2012-05-25 |
Gilead Sciences Inc |
Purine derivatives and their use as modulators of toll-like receptor 7
|
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
TW200922569A
(en)
|
2007-08-10 |
2009-06-01 |
Genelabs Tech Inc |
Certain nitrogen containing bicyclic chemical entities for treating viral infections
|
|
UY31531A1
(es)
|
2007-12-17 |
2009-08-03 |
|
Sales derivadas de 8-oxoadenina composiciones farmacéuticas que las contienen y su uso en terapia como moduladores de receptor tipo toll (tlr)
|
|
WO2009151910A2
(en)
|
2008-05-25 |
2009-12-17 |
Wyeth |
Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer
|
|
US8946239B2
(en)
|
2008-07-10 |
2015-02-03 |
Duquesne University Of The Holy Spirit |
Substituted pyrrolo, -furano, and cyclopentylpyrimidines having antimitotic and/or antitumor activity and methods of use thereof
|
|
EP2324025A1
(en)
|
2008-08-11 |
2011-05-25 |
Smithkline Beecham Corporation |
Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
|
|
US8802684B2
(en)
|
2008-08-11 |
2014-08-12 |
Glaxosmithkline Llc |
Adenine derivatives
|
|
WO2010018132A1
(en)
|
2008-08-11 |
2010-02-18 |
Smithkline Beecham Corporation |
Compounds
|
|
UA103195C2
(uk)
|
2008-08-11 |
2013-09-25 |
Глаксосмитклайн Ллк |
Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
|
|
US8575181B2
(en)
|
2008-08-11 |
2013-11-05 |
Glaxosmithkline Llc |
Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
|
|
SG193149A1
(en)
|
2008-08-11 |
2013-09-30 |
Glaxosmithkline Llc |
Novel adenine derivatives
|
|
CN102548999A
(zh)
|
2009-01-20 |
2012-07-04 |
山东轩竹医药科技有限公司 |
含有取代的含氮稠杂环的头孢菌素衍生物
|
|
WO2010111406A2
(en)
*
|
2009-03-24 |
2010-09-30 |
Myriad Pharmaceuticals, Inc. |
Compounds and therapeutic uses thereof
|
|
ES2732999T3
(es)
|
2009-08-07 |
2019-11-27 |
Glaxosmithkline Biologicals Sa |
Derivados de oxoadenina lipidada
|
|
WO2011098452A1
(en)
|
2010-02-10 |
2011-08-18 |
Glaxosmithkline Llc |
6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate
|
|
US8575340B2
(en)
|
2010-02-10 |
2013-11-05 |
Glaxosmithkline Llc |
Purine derivatives and their pharmaceutical uses
|
|
WO2012009258A2
(en)
|
2010-07-13 |
2012-01-19 |
Edward Roberts |
Peptidomimetic galanin receptor modulators
|
|
US20120171229A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
WO2012106343A2
(en)
|
2011-02-01 |
2012-08-09 |
The Board Of Trustees Of The University Of Illinois |
Hdac inhibitors and therapeutic methods using the same
|
|
EP2670244B1
(en)
|
2011-02-04 |
2018-04-11 |
Duquesne University of The Holy Spirit |
Bicyclic and tricyclic pyrimidine tyrosine kinase inhibitors with antitubulin activity and methods of treating a patient
|
|
ES2693122T3
(es)
|
2011-07-22 |
2018-12-07 |
Glaxosmithkline Llc |
Composición
|
|
PE20150730A1
(es)
|
2012-08-24 |
2015-06-02 |
Glaxosmithkline Llc |
Compuestos de pirazolopirimidina
|
|
BR112015011447A2
(pt)
|
2012-11-20 |
2017-07-11 |
Glaxosmithkline Llc |
composto da fórmula i, composição farmacêutica e de vacina, e, uso de um composto
|
|
BR112015011439A2
(pt)
|
2012-11-20 |
2017-07-11 |
Glaxosmithkline Llc |
composto, composição farmacêutica, composição de vacina, e, uso de um composto
|
|
PL2922549T3
(pl)
|
2012-11-20 |
2017-11-30 |
Glaxosmithkline Llc |
Nowe związki
|
|
JP6452711B2
(ja)
|
2014-02-20 |
2019-01-16 |
グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited |
ヒトインターフェロンの誘導物質としてのピロロ[3,2]ピリミジン誘導体
|