|
NL154598B
(nl)
|
1970-11-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
|
|
US3817837A
(en)
|
1971-05-14 |
1974-06-18 |
Syva Corp |
Enzyme amplification assay
|
|
US3939350A
(en)
|
1974-04-29 |
1976-02-17 |
Board Of Trustees Of The Leland Stanford Junior University |
Fluorescent immunoassay employing total reflection for activation
|
|
US3996345A
(en)
|
1974-08-12 |
1976-12-07 |
Syva Company |
Fluorescence quenching with immunological pairs in immunoassays
|
|
US4275149A
(en)
|
1978-11-24 |
1981-06-23 |
Syva Company |
Macromolecular environment control in specific receptor assays
|
|
US4277437A
(en)
|
1978-04-05 |
1981-07-07 |
Syva Company |
Kit for carrying out chemically induced fluorescence immunoassay
|
|
US4366241A
(en)
|
1980-08-07 |
1982-12-28 |
Syva Company |
Concentrating zone method in heterogeneous immunoassays
|
|
US4563304A
(en)
|
1981-02-27 |
1986-01-07 |
Pharmacia Fine Chemicals Ab |
Pyridine compounds modifying proteins, polypeptides or polysaccharides
|
|
US4957939A
(en)
|
1981-07-24 |
1990-09-18 |
Schering Aktiengesellschaft |
Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
|
|
US4472509A
(en)
|
1982-06-07 |
1984-09-18 |
Gansow Otto A |
Metal chelate conjugated monoclonal antibodies
|
|
US4938948A
(en)
|
1985-10-07 |
1990-07-03 |
Cetus Corporation |
Method for imaging breast tumors using labeled monoclonal anti-human breast cancer antibodies
|
|
WO1989006692A1
(en)
|
1988-01-12 |
1989-07-27 |
Genentech, Inc. |
Method of treating tumor cells by inhibiting growth factor receptor function
|
|
US20040049014A1
(en)
|
1988-12-28 |
2004-03-11 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5108921A
(en)
|
1989-04-03 |
1992-04-28 |
Purdue Research Foundation |
Method for enhanced transmembrane transport of exogenous molecules
|
|
JPH049249A
(ja)
|
1990-04-27 |
1992-01-14 |
Kusuda:Kk |
塗型剤吹き付け機
|
|
US6916605B1
(en)
|
1990-07-10 |
2005-07-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
EP1306095A3
(en)
|
1992-03-05 |
2003-06-25 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
US5965132A
(en)
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
US20030148406A1
(en)
|
1992-03-17 |
2003-08-07 |
David John King |
Multivalent antigen-binding proteins
|
|
AU691811B2
(en)
|
1993-06-16 |
1998-05-28 |
Celltech Therapeutics Limited |
Antibodies
|
|
WO1997011971A1
(en)
|
1995-09-28 |
1997-04-03 |
Alexion Pharmaceuticals, Inc. |
Porcine cell interaction proteins
|
|
US6596850B1
(en)
|
1998-01-30 |
2003-07-22 |
Ixsys, Incorporated |
Anti-αv3β3 recombinant human antibodies, nucleic acids encoding same
|
|
EP1150688A4
(en)
|
1998-10-19 |
2004-06-16 |
Yeda Res & Dev |
TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS BY NEGATIVE REGULATION OF THE AUTO-IMMUNE RESPONSE TO AUTOANTIGENS
|
|
US20040031072A1
(en)
|
1999-05-06 |
2004-02-12 |
La Rosa Thomas J. |
Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
|
|
IT1307309B1
(it)
|
1999-12-30 |
2001-10-30 |
Enea Ente Nuove Tec |
Peptidi stabilizzanti, polipeptidi ed anticorpi che li comprendono.
|
|
DZ3332A1
(fr)
|
2000-03-31 |
2001-10-11 |
Purdue Research Foundation |
Methode de traitement a l'aide de conjugues ligand-immunogene
|
|
DE10037759A1
(de)
|
2000-08-03 |
2002-07-04 |
Gruenenthal Gmbh |
Screeningverfahren
|
|
JP4279554B2
(ja)
|
2001-02-19 |
2009-06-17 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
T細胞エピトープの識別方法および低減された免疫原性を有する分子の製造方法
|
|
WO2002071928A2
(en)
|
2001-03-14 |
2002-09-19 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
|
IL158532A0
(en)
|
2001-05-02 |
2004-05-12 |
Purdue Research Foundation |
Treatment and diagnosis of macrophage mediated disease
|
|
US7314974B2
(en)
|
2002-02-21 |
2008-01-01 |
Monsanto Technology, Llc |
Expression of microbial proteins in plants for production of plants with improved properties
|
|
AU2003211337A1
(en)
|
2002-03-01 |
2003-09-16 |
Japan Envirochemicals, Ltd. |
Proteins capable of binding to female sex hormones and process for producing the same
|
|
AU2003224073C1
(en)
|
2002-04-22 |
2010-03-11 |
AgroProtect GmbH |
Antibodies, recombinant antibodies, recombinant antibody fragments and fusions mediated plant disease resistance against fungi
|
|
WO2004043989A2
(en)
|
2002-11-07 |
2004-05-27 |
Medarex, Inc. |
Human monoclonal antibodies to heparanase
|
|
EP1481993A1
(en)
|
2003-05-28 |
2004-12-01 |
Xerion Pharmaceuticals AG |
Modulation of the poliovirus receptor function
|
|
US20050255114A1
(en)
|
2003-04-07 |
2005-11-17 |
Nuvelo, Inc. |
Methods and diagnosis for the treatment of preeclampsia
|
|
US20050025763A1
(en)
|
2003-05-08 |
2005-02-03 |
Protein Design Laboratories, Inc. |
Therapeutic use of anti-CS1 antibodies
|
|
KR101351122B1
(ko)
|
2003-05-09 |
2014-01-14 |
듀크 유니버시티 |
Cd20-특이적 항체 및 이를 이용한 방법
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
KR20060080535A
(ko)
|
2003-05-14 |
2006-07-10 |
이뮤노젠 아이엔씨 |
약물 콘쥬게이트 조성물
|
|
US7276497B2
(en)
|
2003-05-20 |
2007-10-02 |
Immunogen Inc. |
Cytotoxic agents comprising new maytansinoids
|
|
US20050170368A1
(en)
|
2003-07-02 |
2005-08-04 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US7622112B2
(en)
|
2003-12-05 |
2009-11-24 |
Jody Berry |
Anti-SARS monoclonal antibodies
|
|
CA2556027C
(en)
|
2004-02-12 |
2015-11-24 |
Morphotek, Inc. |
Monoclonal antibodies that specifically block biological activity of a tumor antigen
|
|
CA2562833A1
(en)
|
2004-04-27 |
2005-11-03 |
Galapagos N.V. |
Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts
|
|
US7241598B2
(en)
|
2004-06-29 |
2007-07-10 |
The Chinese University Of Hong Kong |
Frame-shifting PCR for germline immunoglobulin genes retrieval and antibody engineering
|
|
KR20070094890A
(ko)
|
2004-10-25 |
2007-09-27 |
머크 앤드 캄파니 인코포레이티드 |
안티 addl 항체 및 그 용도
|
|
EP1827079A4
(en)
|
2004-12-21 |
2012-04-11 |
Monsanto Technology Llc |
TRANSGENIC PLANTS WITH ADVANCED AGRONOMIC CHARACTERISTICS
|
|
BRPI0518994A2
(pt)
|
2004-12-31 |
2008-12-02 |
Biogen Idec Inc |
anticorpos ou polipeptÍdeos que se ligam a br3, seus usos e formulaÇÕes lÍquidas
|
|
WO2007094754A2
(en)
|
2005-01-27 |
2007-08-23 |
The Regents Of The University Of Califordnia |
Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
|
|
US7608413B1
(en)
|
2005-03-25 |
2009-10-27 |
Celera Corporation |
Kidney disease targets and uses thereof
|
|
JP5238936B2
(ja)
|
2005-03-25 |
2013-07-17 |
ジーアイティーアール,インク. |
Gitr結合分子およびその使用
|
|
DE602006012816D1
(de)
*
|
2005-03-30 |
2010-04-22 |
Endocyte Inc |
Tifizierung von zellulären folat vitamin rezeptoren
|
|
EP2172487A1
(en)
*
|
2005-04-22 |
2010-04-07 |
Morphotek Inc. |
Antibodies with Immune Effector Activity that Internalize in Folate Receptor Alpha-Positive Cells
|
|
WO2006121207A1
(en)
|
2005-05-12 |
2006-11-16 |
Oncotherapy Science, Inc. |
Methods for damaging cells using effector function of anti-dsc2 antibody
|
|
US20090215165A1
(en)
|
2005-05-20 |
2009-08-27 |
James Rance |
High-level expression of recombinant antibody in a mammalian host cell
|
|
KR20080039844A
(ko)
|
2005-05-24 |
2008-05-07 |
아베스타 겐그레인 테크놀로지스 피브이티 리미티드 |
B―세포 림프종 치료를 위한 cd20에 대한 모노클로날항체의 제조 방법
|
|
JP5175723B2
(ja)
|
2005-07-05 |
2013-04-03 |
パーデュー・リサーチ・ファウンデーション |
単球介在性疾患を治療するための組成物の調製
|
|
US7521195B1
(en)
|
2005-07-21 |
2009-04-21 |
Celera Corporation |
Lung disease targets and uses thereof
|
|
CA2619725C
(en)
|
2005-08-18 |
2016-06-07 |
Ramot At Tel Aviv University Ltd. |
Single chain antibodies against beta-amyloid peptide
|
|
ES2543341T3
(es)
|
2005-09-13 |
2015-08-18 |
National Research Council Of Canada |
Métodos y composiciones para modular la actividad de células tumorales
|
|
WO2007047796A2
(en)
|
2005-10-17 |
2007-04-26 |
Institute For Systems Biology |
Tissue-and serum-derived glycoproteins and methods of their use
|
|
EP1790664A1
(en)
|
2005-11-24 |
2007-05-30 |
Ganymed Pharmaceuticals AG |
Monoclonal antibodies against claudin-18 for treatment of cancer
|
|
SI1964852T1
(sl)
|
2005-12-20 |
2013-09-30 |
Sbi Biotech Co. Ltd. |
Proti-ilt7 protitelo
|
|
CA2685300C
(en)
|
2006-06-01 |
2017-01-03 |
Mayo Foundation For Medical Education And Research |
Immunity to folate receptors
|
|
CA2655933C
(en)
|
2006-06-23 |
2014-09-09 |
Alethia Biotherapeutics Inc. |
Polynucleotides and polypeptide sequences involved in cancer
|
|
US7910702B2
(en)
|
2006-07-28 |
2011-03-22 |
The Governors Of The University Of Alberta |
Recombinant antibodies to sclerotinia antigens
|
|
CA2660286A1
(en)
|
2006-08-09 |
2008-02-21 |
Homestead Clinical Corporation |
Organ-specific proteins and methods of their use
|
|
EP1900752A1
(en)
*
|
2006-09-15 |
2008-03-19 |
DOMPE' pha.r.ma s.p.a. |
Human anti-folate receptor alpha antibodies and antibody fragments for the radioimmunotherapy of ovarian carcinoma
|
|
EP1900533A1
(de)
|
2006-09-16 |
2008-03-19 |
J. Zimmer Maschinenbau Gesellschaft m.b.H. |
Vorrichtung zum Auftragen von Substanz auf flächige Substrate
|
|
RU2537245C2
(ru)
|
2006-10-12 |
2014-12-27 |
Чугаи Сейяку Кабусики Кайся |
Диагностика и лечение злокачественной опухоли с использованием антитела против ereg
|
|
CA2672581A1
(en)
|
2006-12-14 |
2008-06-19 |
Forerunner Pharma Research Co., Ltd. |
Anti-claudin 3 monoclonal antibody and treatment and diagnosis of cancer using the same
|
|
US8465741B2
(en)
|
2006-12-20 |
2013-06-18 |
Mmrglobal, Inc. |
Antibodies and methods for making and using them
|
|
US20080227704A1
(en)
|
2006-12-21 |
2008-09-18 |
Kamens Joanne S |
CXCL13 binding proteins
|
|
US20100104626A1
(en)
|
2007-02-16 |
2010-04-29 |
Endocyte, Inc. |
Methods and compositions for treating and diagnosing kidney disease
|
|
EP2606911A1
(en)
|
2007-02-16 |
2013-06-26 |
KTB Tumorforschungsgesellschaft mbH |
Receptor And Antigen Targeted Prodrug
|
|
WO2008145136A1
(en)
|
2007-05-30 |
2008-12-04 |
Aarhus Universitet |
Stat3 inactivation by inhibition of the folate receptor pathway
|
|
BRPI0812970A2
(pt)
|
2007-06-25 |
2019-09-24 |
Endocyte Inc |
conjugados contendo espaçadores hidrofílicos
|
|
AU2008282863A1
(en)
|
2007-07-31 |
2009-02-05 |
Merck Sharp & Dohme Corp. |
IGF-1R specific antibodies useful in the detection and diagnosis of cellular proliferative disorders
|
|
CN101139613B
(zh)
|
2007-08-01 |
2011-06-08 |
姜荣锡 |
抗肿瘤二元多肽及其应用与制备方法
|
|
WO2009032974A2
(en)
|
2007-09-06 |
2009-03-12 |
Tripath Imaging, Inc. |
Nucleic acid-based methods for the detection of ovarian cancer
|
|
ES2546086T3
(es)
|
2007-12-21 |
2015-09-18 |
Novartis Ag |
Sistema de selección en un cultivo de células eucariotas basado en un gen receptor de folato unido a la membrana
|
|
AU2009203464A1
(en)
|
2008-01-11 |
2009-07-16 |
Forerunner Pharma Research Co., Ltd. |
Anti-CLDN6 antibody
|
|
WO2009132081A2
(en)
|
2008-04-24 |
2009-10-29 |
The Research Foundation Of State University Of New York |
Monoclonal antibody-based targeting of folate receptors
|
|
NZ588884A
(en)
|
2008-04-30 |
2013-05-31 |
Immunogen Inc |
Cross-linkers and their uses
|
|
UA108598C2
(xx)
|
2008-04-30 |
2015-05-25 |
|
Високоефективні кон'югати та гідрофільні зшиваючі агенти (лінкери)
|
|
US8383351B2
(en)
|
2008-06-11 |
2013-02-26 |
Oxford Brookes University |
Antibody to inhibin/ activin β-B subunit
|
|
JP5675619B2
(ja)
|
2008-09-17 |
2015-02-25 |
エンドサイト, インク.Endocyte, Inc. |
葉酸拮抗薬の葉酸受容体結合性コンジュゲート
|
|
WO2010033913A1
(en)
|
2008-09-22 |
2010-03-25 |
Icb International, Inc. |
Antibodies, analogs and uses thereof
|
|
EP2367939A4
(en)
|
2008-11-20 |
2012-07-04 |
Oncotherapy Science Inc |
METHOD FOR DIAGNOSIS OR TREATMENT OF PROSTATE CANCER
|
|
CN101440130B
(zh)
|
2008-11-21 |
2011-07-27 |
中国人民解放军第四军医大学 |
一种抗人IL-13Rα2单克隆抗体的重链和轻链的可变区
|
|
JP5923035B2
(ja)
|
2009-03-24 |
2016-05-24 |
バイオセプト インコーポレイティッド |
細胞の捕捉および解析のデバイスおよび方法
|
|
WO2011016238A1
(en)
*
|
2009-08-06 |
2011-02-10 |
Immunas Pharma, Inc. |
Antibodies that specifically bind to a beta oligomers and use thereof
|
|
US20120252022A1
(en)
|
2009-09-21 |
2012-10-04 |
Paul Walfish |
Methods and compositions for the diagnosis and treatment of thyroid cancer
|
|
WO2011100398A1
(en)
|
2010-02-10 |
2011-08-18 |
Immunogen, Inc. |
Cd20 antibodies and uses thereof
|
|
CN105777907B
(zh)
|
2010-02-24 |
2020-03-17 |
伊缪诺金公司 |
叶酸受体1抗体与免疫缀合物以及其用途
|
|
SG189957A1
(en)
|
2010-11-05 |
2013-06-28 |
Morphotek Inc |
Folate receptor alpha as a diagnostic and prognostic marker for folate receptor alpha-expressing cancers
|
|
WO2012135517A2
(en)
*
|
2011-03-29 |
2012-10-04 |
Immunogen, Inc. |
Preparation of maytansinoid antibody conjugates by a one-step process
|
|
EA033468B1
(ru)
*
|
2011-03-29 |
2019-10-31 |
Immunogen Inc |
Способы получения конъюгата "антитело-майтансиноид"
|
|
KR20140019415A
(ko)
*
|
2011-03-29 |
2014-02-14 |
이뮤노젠 아이엔씨 |
향상된 균질성의 접합체를 제조하기 위한 방법
|
|
ES2661466T3
(es)
|
2011-04-01 |
2018-04-02 |
Immunogen, Inc. |
Métodos para aumentar la eficacia de la terapia contra el cáncer con FOLR1
|
|
US20120282282A1
(en)
|
2011-04-04 |
2012-11-08 |
Immunogen, Inc. |
Methods for Decreasing Ocular Toxicity of Antibody Drug Conjugates
|
|
WO2012145112A2
(en)
|
2011-04-18 |
2012-10-26 |
Immunogen, Inc. |
Novel maytansinoid derivatives with sulfoxide linker
|
|
CN107011439B
(zh)
|
2011-07-15 |
2020-11-10 |
卫材R&D管理有限公司 |
抗叶酸受体α抗体及其应用
|
|
SG11201500938XA
(en)
|
2012-08-31 |
2015-04-29 |
Immunogen Inc |
Diagnostic assays and kits for detection of folate receptor 1
|
|
WO2014055842A1
(en)
|
2012-10-04 |
2014-04-10 |
Immunogen, Inc. |
Process for preparing stable antibody maytansinoid conjugates
|
|
EP2997044A4
(en)
|
2013-05-14 |
2017-03-22 |
ImmunoGen, Inc. |
Anti-folr1 immunoconjugate dosing regimens
|
|
NZ717140A
(en)
|
2013-08-30 |
2022-05-27 |
Immunogen Inc |
Antibodies and assays for detection of folate receptor 1
|
|
JP6463744B2
(ja)
*
|
2013-10-08 |
2019-02-06 |
イミュノジェン, インコーポレイテッド |
抗folr1免疫抱合体投薬レジメン
|
|
US20150297744A1
(en)
*
|
2014-03-28 |
2015-10-22 |
Immunogen, Inc. |
Anti-FOLR1 Immunoconjugate Dosing Regimens
|
|
CN107110840A
(zh)
|
2014-07-01 |
2017-08-29 |
爱科谱迅病理研究公司 |
针对化疗靶标的srm测定
|
|
MA40539A
(fr)
|
2014-09-02 |
2016-03-10 |
Immunogen Inc |
Procédés de formulation de compositions de conjugués anticorps-médicaments
|
|
CN122075735A
(zh)
|
2015-09-17 |
2026-05-26 |
伊缪诺金公司 |
包含抗folr1免疫缀合物的治疗组合
|
|
IL298414B2
(en)
|
2017-02-28 |
2024-12-01 |
Immunogen Inc |
Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof
|
|
BR112019023909A8
(pt)
|
2017-05-16 |
2023-04-11 |
Immunogen Inc |
Uso de um imunoconjugado que se liga a folr1, e, uso de um imunoconjugado que se liga a folr1 e pembrolizumab
|