JP2014508756A5 - - Google Patents
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- JP2014508756A5 JP2014508756A5 JP2013554590A JP2013554590A JP2014508756A5 JP 2014508756 A5 JP2014508756 A5 JP 2014508756A5 JP 2013554590 A JP2013554590 A JP 2013554590A JP 2013554590 A JP2013554590 A JP 2013554590A JP 2014508756 A5 JP2014508756 A5 JP 2014508756A5
- Authority
- JP
- Japan
- Prior art keywords
- pain
- compound
- alkyl
- compound according
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161444250P | 2011-02-18 | 2011-02-18 | |
| US61/444,250 | 2011-02-18 | ||
| US201161540121P | 2011-09-28 | 2011-09-28 | |
| US61/540,121 | 2011-09-28 | ||
| PCT/US2012/025374 WO2012112743A1 (en) | 2011-02-18 | 2012-02-16 | Chroman - spirocyclic piperidine amides as modulators of ion channels |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015240777A Division JP2016034986A (ja) | 2011-02-18 | 2015-12-10 | イオンチャネルのモジュレーターとしてのクロマン−スピロ環式ピペリジンアミド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014508756A JP2014508756A (ja) | 2014-04-10 |
| JP2014508756A5 true JP2014508756A5 (https=) | 2015-04-02 |
| JP5940562B2 JP5940562B2 (ja) | 2016-06-29 |
Family
ID=45757227
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013554590A Expired - Fee Related JP5940562B2 (ja) | 2011-02-18 | 2012-02-16 | イオンチャネルのモジュレーターとしてのクロマン−スピロ環式ピペリジンアミド |
| JP2015240777A Pending JP2016034986A (ja) | 2011-02-18 | 2015-12-10 | イオンチャネルのモジュレーターとしてのクロマン−スピロ環式ピペリジンアミド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015240777A Pending JP2016034986A (ja) | 2011-02-18 | 2015-12-10 | イオンチャネルのモジュレーターとしてのクロマン−スピロ環式ピペリジンアミド |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10385070B2 (https=) |
| EP (1) | EP2675812B1 (https=) |
| JP (2) | JP5940562B2 (https=) |
| CN (1) | CN103443105A (https=) |
| AU (1) | AU2012217616B2 (https=) |
| CA (1) | CA2827311A1 (https=) |
| MX (1) | MX2013009393A (https=) |
| WO (1) | WO2012112743A1 (https=) |
Families Citing this family (64)
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| WO2010051497A1 (en) | 2008-10-31 | 2010-05-06 | Pain Therapeutics, Inc. | Filamin a binding anti-inflammatory and analgesic |
| EP2498600B1 (en) | 2008-10-31 | 2016-03-02 | Pain Therapeutics, Inc. | Filamin a-binding anti-inflammatory analgesic |
| EP2414348B1 (en) | 2009-04-03 | 2013-11-20 | Merck Sharp & Dohme Corp. | Bicyclic piperidine and piperazine derivatives as gpcr modulators for the treatment of obesity, diabetes and other metabolic disorders |
| WO2010151597A1 (en) | 2009-06-26 | 2010-12-29 | Schering Corporation | Methods for using pyrrolo-benzo-1,4-diazines as sodium channel blockers |
| US8354403B2 (en) * | 2009-08-27 | 2013-01-15 | Merck Sharp & Dohme Corp. | Pyrrolidine derived beta 3 adrenergic receptor agonists |
| US8633183B2 (en) | 2010-01-26 | 2014-01-21 | Boehringer Ingelheim International Gmbh | 5-alkynyl-pyrimidines |
| US8598164B2 (en) | 2010-05-06 | 2013-12-03 | Vertex Pharmaceuticals Incorporated | Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels |
| WO2012077655A1 (ja) * | 2010-12-07 | 2012-06-14 | 塩野義製薬株式会社 | Ｇｐｒ１１９アゴニスト活性を有するスピロ誘導体 |
| MX355907B (es) | 2011-02-02 | 2018-05-04 | Vertex Pharma | Pirrolopirazina-piperidina espirociclica-amidas como moduladores de canales de ionicos. |
| MX347982B (es) | 2011-03-14 | 2017-05-22 | Vertex Pharma | Morfolina-piperidina espirociclica-amidas como moduladores de canales ionicos. |
-
2012
- 2012-02-16 JP JP2013554590A patent/JP5940562B2/ja not_active Expired - Fee Related
- 2012-02-16 EP EP12705765.1A patent/EP2675812B1/en active Active
- 2012-02-16 WO PCT/US2012/025374 patent/WO2012112743A1/en not_active Ceased
- 2012-02-16 US US13/398,184 patent/US10385070B2/en active Active
- 2012-02-16 MX MX2013009393A patent/MX2013009393A/es unknown
- 2012-02-16 AU AU2012217616A patent/AU2012217616B2/en not_active Ceased
- 2012-02-16 CN CN2012800133657A patent/CN103443105A/zh active Pending
- 2012-02-16 CA CA2827311A patent/CA2827311A1/en not_active Abandoned
-
2015
- 2015-12-10 JP JP2015240777A patent/JP2016034986A/ja active Pending
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