CN103443105A - 作为离子通道调节剂的苯并二氢吡喃-螺环哌啶酰胺 - Google Patents

作为离子通道调节剂的苯并二氢吡喃-螺环哌啶酰胺 Download PDF

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Publication number
CN103443105A
CN103443105A CN2012800133657A CN201280013365A CN103443105A CN 103443105 A CN103443105 A CN 103443105A CN 2012800133657 A CN2012800133657 A CN 2012800133657A CN 201280013365 A CN201280013365 A CN 201280013365A CN 103443105 A CN103443105 A CN 103443105A
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compound
pain
och
alkoxyl group
alkyl
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Chinese (zh)
Inventor
S·S·哈迪达-鲁阿
M·T·米勒
E·A·卡莱尔
B·R·比尔
V·阿鲁姆盖姆
M·P·丹尼诺
周竞兰
J·尤伊
B·A·弗里曼
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
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  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CN2012800133657A 2011-02-18 2012-02-16 作为离子通道调节剂的苯并二氢吡喃-螺环哌啶酰胺 Pending CN103443105A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161444250P 2011-02-18 2011-02-18
US61/444,250 2011-02-18
US201161540121P 2011-09-28 2011-09-28
US61/540,121 2011-09-28
PCT/US2012/025374 WO2012112743A1 (en) 2011-02-18 2012-02-16 Chroman - spirocyclic piperidine amides as modulators of ion channels

Publications (1)

Publication Number Publication Date
CN103443105A true CN103443105A (zh) 2013-12-11

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CN2012800133657A Pending CN103443105A (zh) 2011-02-18 2012-02-16 作为离子通道调节剂的苯并二氢吡喃-螺环哌啶酰胺

Country Status (8)

Country Link
US (1) US10385070B2 (https=)
EP (1) EP2675812B1 (https=)
JP (2) JP5940562B2 (https=)
CN (1) CN103443105A (https=)
AU (1) AU2012217616B2 (https=)
CA (1) CA2827311A1 (https=)
MX (1) MX2013009393A (https=)
WO (1) WO2012112743A1 (https=)

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CN103517910B (zh) 2011-03-14 2016-12-14 沃泰克斯药物股份有限公司 作为离子通道调节剂的吗啉-螺环哌啶酰胺
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UA119147C2 (uk) 2013-07-19 2019-05-10 Вертекс Фармасьютікалз Інкорпорейтед Сульфонаміди як модулятори натрієвих каналів
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