|
US4545931A
(en)
|
1983-01-03 |
1985-10-08 |
Scripps Clinic And Research Foundation |
Synthetic heat-stable enterotoxin polypeptide of Escherichia coli
|
|
CH658973A5
(fr)
|
1983-12-29 |
1986-12-31 |
Nestle Sa |
Produit aromatisant.
|
|
JPS6197229A
(ja)
|
1984-10-18 |
1986-05-15 |
Chugai Pharmaceut Co Ltd |
安定なエリトロポエチン製剤
|
|
DE3729863A1
(de)
|
1987-09-05 |
1989-03-16 |
Boehringer Mannheim Gmbh |
Stabilisierte erythropoietin-lyophilisate
|
|
JPS649938A
(en)
|
1987-06-30 |
1989-01-13 |
Agency Ind Science Techn |
Oral ingestive composition
|
|
JPH0223849A
(ja)
*
|
1988-06-08 |
1990-01-26 |
Morishita Pharmaceut Co Ltd |
ペプチド含有栄養輸液組成物
|
|
EP0420964A4
(en)
|
1989-04-11 |
1991-09-25 |
Immunobiology Research Institute, Inc. |
Lyophilized peptide formulations
|
|
US5130298A
(en)
|
1989-05-16 |
1992-07-14 |
Ethicon, Inc. |
Stabilized compositions containing epidermal growth factor
|
|
IT1240314B
(it)
|
1989-09-28 |
1993-12-07 |
Immunobiology Research Institutes, Inc. |
Formulazioni acquose stabilizzate di piccoli peptidi.
|
|
US5221495A
(en)
|
1990-04-13 |
1993-06-22 |
Colgate-Palmolive Company |
Enzyme stabilizing composition and stabilized enzyme containing built detergent compositions
|
|
US5451410A
(en)
|
1993-04-22 |
1995-09-19 |
Emisphere Technologies, Inc. |
Modified amino acids for encapsulating active agents
|
|
US6022858A
(en)
|
1991-12-20 |
2000-02-08 |
Novo Nordisk A/S |
Pharmaceutical formulation of human-growth hormone pretreated with zinc salt
|
|
US5969097A
(en)
|
1992-06-23 |
1999-10-19 |
G. D. Searle & Co. |
Human guanylin
|
|
US6284727B1
(en)
|
1993-04-07 |
2001-09-04 |
Scios, Inc. |
Prolonged delivery of peptides
|
|
US5681811A
(en)
|
1993-05-10 |
1997-10-28 |
Protein Delivery, Inc. |
Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
|
|
EP0804174A4
(en)
|
1993-07-21 |
1998-09-09 |
Univ Kentucky Res Found |
MULTI-CHAMBER HARD CAPSULES WITH CONTROLLED DELIVERY CHARACTERISTICS
|
|
US5518888A
(en)
|
1993-10-26 |
1996-05-21 |
Thomas Jefferson University |
ST receptor binding compounds and methods of using the same
|
|
US5489670A
(en)
|
1993-10-29 |
1996-02-06 |
G. D. Searle & Co. |
Human uroguanylin
|
|
US6383788B1
(en)
|
1994-03-04 |
2002-05-07 |
Genentech, Inc. |
Minimizing thermally induced aggregation of DNase in solution with calcium
|
|
US5654278A
(en)
|
1994-10-13 |
1997-08-05 |
Novo Nordisk A/S |
Composition and method comprising growth hormone and leucine
|
|
US5593696A
(en)
|
1994-11-21 |
1997-01-14 |
Mcneil-Ppc, Inc. |
Stabilized composition of famotidine and sucralfate for treatment of gastrointestinal disorders
|
|
US5904935A
(en)
|
1995-06-07 |
1999-05-18 |
Alza Corporation |
Peptide/protein suspending formulations
|
|
ZA965368B
(en)
|
1995-07-14 |
1997-01-14 |
Novo Nordisk As |
A pharmaceutical formulation
|
|
US5980945A
(en)
|
1996-01-16 |
1999-11-09 |
Societe De Conseils De Recherches Et D'applications Scientifique S.A. |
Sustained release drug formulations
|
|
WO1997033568A1
(en)
|
1996-03-12 |
1997-09-18 |
Novartis Ag |
Filled gelatin capsules having a reduced degree of cross-linking
|
|
RO119862B1
(ro)
|
1996-07-03 |
2005-05-30 |
Alza Corporation |
Formulare stabilă neapoasă şi procedeu pentru prepararea acesteia
|
|
US5916582A
(en)
|
1996-07-03 |
1999-06-29 |
Alza Corporation |
Aqueous formulations of peptides
|
|
US5932547A
(en)
|
1996-07-03 |
1999-08-03 |
Alza Corporation |
Non-aqueous polar aprotic peptide formulations
|
|
WO1998009645A1
(en)
|
1996-09-04 |
1998-03-12 |
Dott Research Laboratory |
Peptide-containing drug compositions for oral administration
|
|
US5705537A
(en)
|
1997-02-24 |
1998-01-06 |
Armstrong World Industries, Inc. |
Phenolic foams having a low formaldehyde evolution
|
|
US6541606B2
(en)
|
1997-12-31 |
2003-04-01 |
Altus Biologics Inc. |
Stabilized protein crystals formulations containing them and methods of making them
|
|
US6087478A
(en)
|
1998-01-23 |
2000-07-11 |
The Rockefeller University |
Crystal of the N-terminal domain of a STAT protein and methods of use thereof
|
|
EP1098636A1
(en)
|
1998-07-23 |
2001-05-16 |
Novo Nordisk A/S |
A wet granulation method for preparing a stable pharmaceutical formulation
|
|
WO2000032172A1
(en)
|
1998-11-27 |
2000-06-08 |
Kanji Takada |
An oral formulation for gastrointestinal drug delivery
|
|
EP1220872A1
(en)
|
1999-10-06 |
2002-07-10 |
Pharmacia Corporation |
Uroguanylin as an intestinal cancer inhibiting agent
|
|
AU2001220765A1
(en)
|
2000-01-24 |
2001-07-31 |
Medtronic Minimed, Inc. |
Mixed buffer system for stabilizing polypeptide formulations
|
|
US6699997B2
(en)
|
2000-06-28 |
2004-03-02 |
Teva Pharmaceutical Industries Ltd. |
Carvedilol
|
|
FR2811884B1
(fr)
|
2000-07-21 |
2003-01-31 |
Oreal |
Utilisation en cosmetique de betainates d'amidon et composition les comprenant associes a au moins un agent benefique pour les matieres keratiniques
|
|
US6613308B2
(en)
|
2000-09-19 |
2003-09-02 |
Advanced Inhalation Research, Inc. |
Pulmonary delivery in treating disorders of the central nervous system
|
|
AU2001296389A1
(en)
|
2000-09-29 |
2002-04-08 |
Cognetix, Inc. |
Stable peptide formulations
|
|
US6896906B2
(en)
|
2000-12-21 |
2005-05-24 |
Nektar Therapeutics |
Storage stable powder compositions of interleukin-4 receptor
|
|
AU2002235520A1
(en)
|
2001-02-02 |
2002-08-19 |
Pharmacia Corporation |
Uroguanylin and cyclooxygenase-2 inhibitor combinations for inhibition of intestinal cancer
|
|
GB0104371D0
(en)
|
2001-02-22 |
2001-04-11 |
Clariant Int Ltd |
Color improving stabilizing compositions comprising leucine
|
|
US6573237B2
(en)
|
2001-03-16 |
2003-06-03 |
Eli Lilly And Company |
Protein formulations
|
|
DE60233040D1
(de)
|
2001-03-29 |
2009-09-03 |
Synergy Pharmaceuticals Inc |
Guanylat-cyclase-rezeptor-agonisten zur behandlung von gewebeentzündung und karzinogenese
|
|
AU2002355542A1
(en)
|
2001-08-09 |
2003-02-24 |
Doctor's Signature Sales And Marketing International Corp. ((Dba)) Life Force International |
Protonic formulation
|
|
US20030104996A1
(en)
|
2001-08-30 |
2003-06-05 |
Tiansheng Li |
L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
|
|
US20040161776A1
(en)
|
2001-10-23 |
2004-08-19 |
Maddon Paul J. |
PSMA formulations and uses thereof
|
|
JP2005530682A
(ja)
|
2001-12-21 |
2005-10-13 |
ノボ ノルディスク アクティーゼルスカブ |
修飾第vii因子ポリペプチドの液体組成物
|
|
JP2003201256A
(ja)
|
2001-12-28 |
2003-07-18 |
Hisamitsu Pharmaceut Co Inc |
大腸送達性経口医薬製剤、大腸癌治療用経口医薬製剤および大腸炎治療用経口医薬製剤
|
|
DE10261126A1
(de)
|
2002-08-13 |
2004-03-04 |
Aventis Behring Gmbh |
Lagerungsstabile, flüssige Fibrinogen-Formulierung
|
|
US20050267222A1
(en)
|
2002-10-22 |
2005-12-01 |
Dainippon Pharmaceutical Co. Ltd. |
Stabilized composition
|
|
JP2006504772A
(ja)
|
2002-10-29 |
2006-02-09 |
アルザ・コーポレーション |
安定化された固体ポリペプチド粒子
|
|
AU2003283688A1
(en)
|
2002-12-11 |
2004-06-30 |
Pfizer Products Inc. |
Controlled-release of an active substance into a high fat environment
|
|
US7371727B2
(en)
|
2003-01-28 |
2008-05-13 |
Microbia, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
US7304036B2
(en)
|
2003-01-28 |
2007-12-04 |
Microbia, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
KR101227626B1
(ko)
|
2003-01-28 |
2013-02-01 |
아이언우드 파마슈티컬스, 인코포레이티드 |
위장병 치료 방법 및 위장병 치료용 조성물
|
|
DE602004012745T2
(de)
|
2003-05-14 |
2009-04-09 |
Indus Biotech Pvt. Ltd. |
Synergistische zusammensetzung zur behandlung von diabetes mellitus
|
|
NZ543859A
(en)
|
2003-06-10 |
2008-01-31 |
Lg Life Sciences Ltd |
Aqueous formulation that has storage stability over a long period without serum albumin comprising human erythropoietin; non-ionic surfactant, polyhydric alcohol, neutral amino acid and sugar alcohol as stabilizers
|
|
JP2007501866A
(ja)
|
2003-06-13 |
2007-02-01 |
マイクロバイア インコーポレイテッド |
胃腸疾患の治療のための方法および組成物
|
|
US7494979B2
(en)
|
2003-06-13 |
2009-02-24 |
Ironwood Pharmaceuticals, Inc. |
Method for treating congestive heart failure and other disorders
|
|
KR100560697B1
(ko)
|
2003-08-06 |
2006-03-16 |
씨제이 주식회사 |
알부민을 함유하지 않는 에리스로포이에틴 제제
|
|
DE202004020676U1
(de)
|
2004-03-10 |
2005-11-10 |
Bioceuticals Arzneimittel Ag |
Erythropoietin-Flüssigformulierung
|
|
WO2006071102A1
(en)
|
2004-12-30 |
2006-07-06 |
Dobeel Co., Ltd. |
Spray-dried composition containing collectin family proteins or variants therof and process for preparing the same
|
|
EP1858352B1
(en)
|
2005-02-18 |
2013-06-05 |
Delante Health AS |
A composition comprising a powder containing microencapsulated polyunsaturated long-chain esterified fatty acids distributed in an effervescent base
|
|
CA2610987C
(en)
*
|
2005-06-10 |
2013-09-10 |
Chugai Seiyaku Kabushiki Kaisha |
Stabilizer for protein preparation comprising meglumine and use thereof
|
|
US20090253634A1
(en)
|
2005-08-19 |
2009-10-08 |
Microbia, Inc. |
Methods and Compositions for the Treatment of Gastrointestinal Disorders
|
|
WO2007044375A2
(en)
|
2005-10-06 |
2007-04-19 |
Nastech Pharmaceutical Company Inc. |
Pth formulations and methods of use
|
|
CN101282657A
(zh)
*
|
2005-10-28 |
2008-10-08 |
雀巢技术公司 |
支链氨基酸的使用方法
|
|
EP1991241A4
(en)
|
2006-02-23 |
2009-07-08 |
Iomedix Sleep Internat Srl |
COMPOSITIONS AND METHODS FOR INTRODUCING AND MAINTAINING HIGH-QUALITY SLEEPING
|
|
WO2007101161A2
(en)
|
2006-02-24 |
2007-09-07 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
ITMI20060629A1
(it)
|
2006-03-31 |
2007-10-01 |
Daniele Giovannone |
Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
|
|
EP2046363A1
(en)
|
2006-07-10 |
2009-04-15 |
Österreichische Akademie der Wissenschaften |
Antimicrobial peptides
|
|
PT2359808E
(pt)
|
2006-08-09 |
2013-08-28 |
Intarcia Therapeutics Inc |
Sistemas de entrega osmótica e montagens de pistão
|
|
KR101524880B1
(ko)
|
2006-08-31 |
2015-06-01 |
노파르티스 아게 |
Hgh를 포함하는 경구 전달용 제약 조성물
|
|
CA2666492C
(en)
|
2006-10-20 |
2012-07-17 |
Douglas Rehder |
Stable polypeptide formulations
|
|
WO2008078189A2
(en)
|
2006-12-20 |
2008-07-03 |
Bayer Healthcare Llc |
Factor vii and viia compositions
|
|
JPWO2008096804A1
(ja)
*
|
2007-02-07 |
2010-05-27 |
テイカ製薬株式会社 |
ラタノプロスト含有点眼剤
|
|
US8779090B2
(en)
|
2007-02-26 |
2014-07-15 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of heart failure and other disorders
|
|
JP4906546B2
(ja)
*
|
2007-03-15 |
2012-03-28 |
株式会社ヤクルト本社 |
レボホリナート含有水溶液製剤
|
|
MX354786B
(es)
|
2007-06-04 |
2018-03-21 |
Synergy Pharmaceuticals Inc |
Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
|
|
JP2009256281A
(ja)
*
|
2008-04-21 |
2009-11-05 |
Teika Seiyaku Kk |
イソプロピルウノプロストン含有点眼剤組成物
|
|
MX385591B
(es)
|
2008-08-15 |
2025-03-18 |
Ironwood Pharmaceuticals Inc |
Formulaciones que contienen linaclotida para administracion oral.
|
|
US20120039949A1
(en)
|
2008-09-04 |
2012-02-16 |
Ironwood Pharmaceuticals, Inc. |
Stable Solid Formulations of GC-C Receptor Agonist Polypeptides Suitable for Oral Administration
|
|
EP2331077A2
(en)
|
2008-09-04 |
2011-06-15 |
Ironwood Pharmaceuticals, Inc. |
Stable forlulation comprising therapeutic polypeptides for oral administration
|
|
EP2373296B1
(en)
|
2008-12-03 |
2016-08-03 |
Synergy Pharmaceuticals Inc. |
Formulations of guanylate cyclase c agonists and methods of use
|
|
WO2011019819A1
(en)
|
2009-08-12 |
2011-02-17 |
Forest Laboratories Holdings Limited |
Orally disintegrating compositions of linaclotide
|
|
WO2011017502A2
(en)
*
|
2009-08-06 |
2011-02-10 |
Ironwood Pharmaceuticals, Inc. |
Linaclotide-containing formulations for oral administration
|
|
CA2808091C
(en)
|
2010-08-11 |
2019-05-21 |
Ironwood Pharmaceuticals, Inc. |
Stable formulations of linaclotide
|
|
CA2835624A1
(en)
|
2011-05-11 |
2012-11-15 |
Ironwood Pharmaceuticals, Inc. |
Treatments for gastrointestinal disorders
|
|
US9617305B2
(en)
|
2011-06-08 |
2017-04-11 |
Ironwood Pharmaceuticals, Inc. |
Treatments for gastrointestinal disorders
|
|
US9527887B2
(en)
|
2011-06-08 |
2016-12-27 |
Ironwood Pharmaceutical, Inc. |
Treatments for gastrointestinal disorders
|
|
JP6312592B2
(ja)
|
2011-08-17 |
2018-04-18 |
アイアンウッド ファーマシューティカルズ インコーポレイテッド |
消化器疾患の治療
|