JPS649938A - Oral ingestive composition - Google Patents
Oral ingestive compositionInfo
- Publication number
- JPS649938A JPS649938A JP62163510A JP16351087A JPS649938A JP S649938 A JPS649938 A JP S649938A JP 62163510 A JP62163510 A JP 62163510A JP 16351087 A JP16351087 A JP 16351087A JP S649938 A JPS649938 A JP S649938A
- Authority
- JP
- Japan
- Prior art keywords
- oral
- ingestive
- oral administration
- peptide
- mentioned
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PURPOSE:To obtain an oral ingestive composition containing a compound peptide or acid addition salt thereof as an active ingredient, having high safety and effective in oral administration. CONSTITUTION:An oral ingestive composition containing a peptide expressed by the formula or acid addition salt thereof as an active ingredient. The above- mentioned peptide is a partial structural substance of bovine casein and obtained by hydrolyzing the above-mentioned protein with trypsin. An organic chemical synthetic technique can be more advantageously used. Although physiologically active peptides are difficult to exhibit effective physiological activity by oral administration because of hydrolysis and inactivation by digestive tract juice or malabsorption from digestive tracts, etc., the afore-mentioned peptides exhibit powerful hypotensive action by oral administration.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62163510A JPS649938A (en) | 1987-06-30 | 1987-06-30 | Oral ingestive composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62163510A JPS649938A (en) | 1987-06-30 | 1987-06-30 | Oral ingestive composition |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS649938A true JPS649938A (en) | 1989-01-13 |
Family
ID=15775236
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62163510A Pending JPS649938A (en) | 1987-06-30 | 1987-06-30 | Oral ingestive composition |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS649938A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999039730A1 (en) * | 1998-02-09 | 1999-08-12 | Kaken Pharmaceutical Co., Ltd. | Oral preparations containing peptides promoting the secretion of growth hormone |
US8748573B2 (en) | 2009-08-06 | 2014-06-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprising linaclotide |
US8802628B2 (en) | 2008-08-15 | 2014-08-12 | Ironwood Pharmaceuticals, Inc. | Stable solid formulation of a GC-C receptor agonist polypeptide suitable for oral administration |
US8933030B2 (en) | 2010-02-17 | 2015-01-13 | Ironwwod Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
US10675325B2 (en) | 2010-08-11 | 2020-06-09 | Ironwood Pharmaceuticals, Inc. | Stable formulations of linaclotide |
-
1987
- 1987-06-30 JP JP62163510A patent/JPS649938A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999039730A1 (en) * | 1998-02-09 | 1999-08-12 | Kaken Pharmaceutical Co., Ltd. | Oral preparations containing peptides promoting the secretion of growth hormone |
US8802628B2 (en) | 2008-08-15 | 2014-08-12 | Ironwood Pharmaceuticals, Inc. | Stable solid formulation of a GC-C receptor agonist polypeptide suitable for oral administration |
US8748573B2 (en) | 2009-08-06 | 2014-06-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprising linaclotide |
US8933030B2 (en) | 2010-02-17 | 2015-01-13 | Ironwwod Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
US10675325B2 (en) | 2010-08-11 | 2020-06-09 | Ironwood Pharmaceuticals, Inc. | Stable formulations of linaclotide |
US10702576B2 (en) | 2010-08-11 | 2020-07-07 | Ironwood Pharmaceuticals, Inc. | Stable formulations of linaclotide |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Du Vigneaud et al. | The synthesis of oxytocin1 | |
NO922232L (en) | PHYSIOLOGICALLY ACTIVE, POLYPEPTIDE-CONTAINING, PHARMACEUTICAL PREPARATIONS | |
BR9507811B1 (en) | polypeptides and pharmaceutical composition. | |
ATE124997T1 (en) | ENZYMATIC REMOVAL OF AN AMINOTERMINAL PROTEIN SEQUENCE. | |
SE9301172D0 (en) | PROCEDURES FOR PREPARING A PEPTIDAL ALCOHOL | |
NO882732L (en) | PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AMINO ACID DERIVATIVES. | |
MY132924A (en) | Hematopoietic stimulation | |
TR200101049T2 (en) | Cyclic tetrapeptide compound and its use | |
EP0130779A3 (en) | Pharmaceutical composition suitable for intestinal administration | |
DK193887D0 (en) | PHYSIOLOGICALLY ACTIVE PEPTID | |
NO871295D0 (en) | PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AMINO ACID DERIVATIVES. | |
NO870049D0 (en) | PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AMINO ACID DERIVATIVES. | |
DE69123278D1 (en) | Use of short chain fatty acids containing lipids to maintain the integrity and function of the gastrointestinal tract | |
EP0225020A3 (en) | Peptides comprising, in sequence, units selected from the amino-acid residues 17 to 24 of vip | |
HUT57204A (en) | Process for producing 4-fluoro-2-///4-methoxy-2-pyridinyl/-methyl/-sulfinyl/-1h-benzimidazol with gastric acid secration-diminishing activity and pharmaceutical compositions containing them | |
JPS649938A (en) | Oral ingestive composition | |
GR3002835T3 (en) | Pharmaceutical compositions containing pentamidine | |
FI93843C (en) | Process for producing an angiogenic factor | |
ATE72120T1 (en) | USE OF PETASITES EXTRACTS IN THE MANUFACTURE OF A MEDICATION FOR THE TREATMENT OF GASTROINTESTINAL DISEASES. | |
Gladner et al. | The biological properties of peptides derived from fibrinogen | |
EP0383481A3 (en) | Anesthetic oral compositions | |
Abel et al. | Some hitherto undescribed properties of the constituents of Witte's peptone | |
EP0261088A3 (en) | Process for the production of heparanlysopeptide sulphate, the product thus obtained and its therapeutic use | |
RU94037232A (en) | Peptides showing organ-protective activity, method of their synthesis and their use | |
JPS6423899A (en) | Novel physiologically active polypeptide |