|
AU2011223969B2
(en)
*
|
2010-03-04 |
2015-06-11 |
Merck Sharp & Dohme Llc |
Inhibitors of catechol O-methyl transferase and their use in the treatment of psychotic disorders
|
|
GB201111705D0
(en)
|
2011-07-07 |
2011-08-24 |
Takeda Pharmaceutical |
Compounds and their use
|
|
GB201111704D0
(en)
|
2011-07-07 |
2011-08-24 |
Takeda Pharmaceutical |
Novel compounds
|
|
JO3115B1
(ar)
|
2011-08-22 |
2017-09-20 |
Takeda Pharmaceuticals Co |
مركبات بيريدازينون واستخدامها كمثبطات daao
|
|
UA111861C2
(uk)
|
2011-11-15 |
2016-06-24 |
Такеда Фармасьютікал Компані Лімітед |
Ароматична гетероциклічна сполука дигідрокси
|
|
TWI638802B
(zh)
*
|
2012-05-24 |
2018-10-21 |
芬蘭商奧利安公司 |
兒茶酚ｏ－甲基轉移酶活性抑制化合物
|
|
CN103845317B
(zh)
*
|
2012-11-28 |
2018-05-08 |
北京生命科学研究所 |
恩他卡朋在预防或治疗肥胖等代谢综合征中的应用
|
|
GB201222711D0
(en)
|
2012-12-17 |
2013-01-30 |
Takeda Pharmaceutical |
Novel compounds
|
|
CA2886139A1
(en)
|
2012-12-27 |
2014-07-03 |
F. Hoffmann-La Roche Ag |
Comt inhibitors
|
|
US9682971B2
(en)
|
2013-03-15 |
2017-06-20 |
Janssen Pharmaceutica Nv |
1,2,5-Substituted benzimidazoles as flap modulators
|
|
US8952177B2
(en)
|
2013-03-15 |
2015-02-10 |
Janssen Pharmaceutica Nv |
1,2,6-substituted benzimidazoles as FLAP modulators
|
|
CN103588702B
(zh)
*
|
2013-10-26 |
2016-01-06 |
浙江大学 |
N-取代苯基吡啶-4-酮衍生物及其制备和应用
|
|
WO2015099107A1
(ja)
|
2013-12-26 |
2015-07-02 |
塩野義製薬株式会社 |
含窒素６員環誘導体およびそれらを含有する医薬組成物
|
|
WO2016123576A1
(en)
|
2015-01-30 |
2016-08-04 |
Lieber Institute For Brain Development |
Comt inhibiting methods and compositions
|
|
EP3957627B1
(en)
|
2015-04-24 |
2024-06-19 |
Shionogi & Co., Ltd |
6-membered heterocyclic derivative and pharmaceutical composition comprising same
|
|
EP3365340B1
(en)
|
2015-10-19 |
2022-08-10 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
US20170145025A1
(en)
|
2015-11-19 |
2017-05-25 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2017091818A1
(en)
|
2015-11-25 |
2017-06-01 |
Lieber Institute For Brain Development |
Comt inhibiting methods and compositions
|
|
CN105481812B
(zh)
*
|
2015-11-30 |
2020-04-21 |
重庆天奕恒化科技有限公司 |
一种5-苄氧基-4-氧代-4h-吡喃-2-羧酸的制备方法
|
|
ES2916874T3
(es)
|
2015-12-17 |
2022-07-06 |
Incyte Corp |
Derivados de N-fenil-piridina-2-carboxamida y su uso como moduladores de la interacción proteína/proteína PD-1/PD-L1
|
|
AU2016379372A1
(en)
|
2015-12-22 |
2018-08-02 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
ES2906460T3
(es)
|
2016-05-06 |
2022-04-18 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
ES2905980T3
(es)
|
2016-05-26 |
2022-04-12 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
BR112018076534A2
(pt)
|
2016-06-20 |
2019-04-02 |
Incyte Corporation |
compostos heterocíclicos como imunomoduladores
|
|
MA45669A
(fr)
|
2016-07-14 |
2019-05-22 |
Incyte Corp |
Composés hétérocycliques utilisés comme immunomodulateurs
|
|
ES2941716T3
(es)
|
2016-08-29 |
2023-05-25 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
KR102528627B1
(ko)
|
2016-10-17 |
2023-05-03 |
시오노기 앤드 컴파니, 리미티드 |
2환성 함질소 헤테로환 유도체 및 그를 함유하는 의약 조성물
|
|
ES2899402T3
(es)
|
2016-12-22 |
2022-03-11 |
Incyte Corp |
Derivados de piridina como inmunomoduladores
|
|
EP3558990B1
(en)
|
2016-12-22 |
2022-08-10 |
Incyte Corporation |
Tetrahydro imidazo[4,5-c]pyridine derivatives as pd-l1 internalization inducers
|
|
ES2874756T3
(es)
|
2016-12-22 |
2021-11-05 |
Incyte Corp |
Derivados de triazolo[1,5-A]piridina como inmunomoduladores
|
|
AU2017382870B2
(en)
|
2016-12-22 |
2022-03-24 |
Incyte Corporation |
Benzooxazole derivatives as immunomodulators
|
|
WO2018119286A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Bicyclic heteroaromatic compounds as immunomodulators
|
|
TW201841911A
(zh)
|
2017-03-31 |
2018-12-01 |
日商富士軟片股份有限公司 |
４－吡啶酮化合物或其鹽、包含４－吡啶酮化合物之藥物組成物及劑
|
|
CN108191746B
(zh)
*
|
2018-02-02 |
2020-06-16 |
暨南大学 |
一种羟基吡啶酮类化合物及其制备方法与应用
|
|
CR20200520A
(es)
|
2018-03-30 |
2021-03-09 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
WO2019217821A1
(en)
|
2018-05-11 |
2019-11-14 |
Incyte Corporation |
Tetrahydro-imidazo[4,5-c]pyridine derivatives as pd-l1 immunomodulators
|
|
WO2020097398A1
(en)
|
2018-11-07 |
2020-05-14 |
Dana-Farber Cancer Institute, Inc. |
Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof
|
|
WO2020097396A1
(en)
|
2018-11-07 |
2020-05-14 |
Dana-Farber Cancer Institute, Inc. |
Benzimidazole derivatives and aza-benzimidazole derivatives as janus kinase 2 inhibitors and uses thereof
|
|
EP3877371A4
(en)
|
2018-11-07 |
2022-07-27 |
Dana-Farber Cancer Institute, Inc. |
IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF
|
|
EP4010342A1
(en)
|
2019-08-09 |
2022-06-15 |
Incyte Corporation |
Salts of a pd-1/pd-l1 inhibitor
|
|
WO2021067217A1
(en)
|
2019-09-30 |
2021-04-08 |
Incyte Corporation |
Pyrido[3,2-d]pyrimidine compounds as immunomodulators
|
|
BR112022009031A2
(pt)
|
2019-11-11 |
2022-10-11 |
Incyte Corp |
Sais e formas cristalinas de um inibidor de pd-1/pd-l1
|
|
CN111170936B
(zh)
*
|
2020-01-19 |
2021-01-01 |
杭州泽德医药科技有限公司 |
3,4-二羟基-n-(1’-苄基-2’-羟乙基)-2-甲基吡啶氯化物及制备和应用
|
|
CA3181537A1
(en)
|
2020-05-06 |
2021-11-11 |
Ajax Therapeutics, Inc. |
6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors
|
|
KR102377058B1
(ko)
|
2020-11-04 |
2022-03-22 |
경북대학교 산학협력단 |
니아스텔라 코리엔시스에서 유래한 카테콜 o-메틸 트렌스퍼라제 및 이의 변이체
|
|
WO2022099075A1
(en)
|
2020-11-06 |
2022-05-12 |
Incyte Corporation |
Crystalline form of a pd-1/pd-l1 inhibitor
|
|
US11780836B2
(en)
|
2020-11-06 |
2023-10-10 |
Incyte Corporation |
Process of preparing a PD-1/PD-L1 inhibitor
|
|
US11866434B2
(en)
|
2020-11-06 |
2024-01-09 |
Incyte Corporation |
Process for making a PD-1/PD-L1 inhibitor and salts and crystalline forms thereof
|
|
EP4267574B1
(en)
|
2020-12-23 |
2025-04-23 |
Ajax Therapeutics, Inc. |
6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors
|
|
US20250276955A1
(en)
*
|
2021-07-19 |
2025-09-04 |
Baylor College Of Medicine |
Coronavirus main protease inhibitors and methods using same
|
|
TW202325289A
(zh)
|
2021-11-09 |
2023-07-01 |
美商雅捷可斯治療公司 |
Ｊａｋ２抑制劑之形式及組合物
|
|
JP7782035B2
(ja)
|
2021-11-09 |
2025-12-08 |
エイジャックス セラピューティクス， インコーポレイテッド |
Ｊａｋ２阻害剤としての６－ヘテロアリールオキシベンゾイミダゾール及びアザベンゾイミダゾール
|
|
CN114716366B
(zh)
*
|
2022-04-13 |
2023-12-26 |
浙江大学 |
3-羟基吡啶-4-酮类衍生物及在抑制肾细胞铁死亡中的应用
|
|
CN116947812B
(zh)
*
|
2023-06-30 |
2025-09-02 |
南京红太阳医药研究院有限公司 |
一种艾司奥美拉唑镁降解杂质的制备方法
|
|
WO2025257687A1
(en)
*
|
2024-06-11 |
2025-12-18 |
Universidade Do Porto |
Hydroxypyridinone compounds as inhibitors of catechol-o-methyltransferase
|