|
EP2542076B1
(en)
*
|
2010-03-04 |
2021-01-13 |
Merck Sharp & Dohme Corp. |
Inhibitors of catechol o-methyl transferase and their use in the treatment of psychotic disorders
|
|
GB201111705D0
(en)
|
2011-07-07 |
2011-08-24 |
Takeda Pharmaceutical |
Compounds and their use
|
|
GB201111704D0
(en)
|
2011-07-07 |
2011-08-24 |
Takeda Pharmaceutical |
Novel compounds
|
|
JO3115B1
(ar)
|
2011-08-22 |
2017-09-20 |
Takeda Pharmaceuticals Co |
مركبات بيريدازينون واستخدامها كمثبطات daao
|
|
AU2012337781B2
(en)
|
2011-11-15 |
2017-07-06 |
Takeda Pharmaceutical Company Limited |
Dihydroxy aromatic heterocyclic compound
|
|
TWI638802B
(zh)
*
|
2012-05-24 |
2018-10-21 |
芬蘭商奧利安公司 |
兒茶酚ｏ－甲基轉移酶活性抑制化合物
|
|
CN103845317B
(zh)
*
|
2012-11-28 |
2018-05-08 |
北京生命科学研究所 |
恩他卡朋在预防或治疗肥胖等代谢综合征中的应用
|
|
GB201222711D0
(en)
|
2012-12-17 |
2013-01-30 |
Takeda Pharmaceutical |
Novel compounds
|
|
KR101685862B1
(ko)
*
|
2012-12-27 |
2016-12-20 |
에프. 호프만-라 로슈 아게 |
Comt 억제제
|
|
US8952177B2
(en)
|
2013-03-15 |
2015-02-10 |
Janssen Pharmaceutica Nv |
1,2,6-substituted benzimidazoles as FLAP modulators
|
|
US9682971B2
(en)
|
2013-03-15 |
2017-06-20 |
Janssen Pharmaceutica Nv |
1,2,5-Substituted benzimidazoles as flap modulators
|
|
CN103588702B
(zh)
*
|
2013-10-26 |
2016-01-06 |
浙江大学 |
N-取代苯基吡啶-4-酮衍生物及其制备和应用
|
|
WO2015099107A1
(ja)
|
2013-12-26 |
2015-07-02 |
塩野義製薬株式会社 |
含窒素６員環誘導体およびそれらを含有する医薬組成物
|
|
JP6858712B2
(ja)
|
2015-01-30 |
2021-04-14 |
リーバー インスティテュート フォー ブレイン ディベロップメントＬｉｅｂｅｒ Ｉｎｓｔｉｔｕｔｅ Ｆｏｒ Ｂｒａｉｎ Ｄｅｖｅｌｏｐｍｅｎｔ |
Ｃｏｍｔ阻害方法及び組成物
|
|
US10774051B2
(en)
|
2015-04-24 |
2020-09-15 |
Shionogi & Co., Ltd. |
6-membered heterocyclic derivatives and pharmaceutical composition comprising the same
|
|
WO2017070089A1
(en)
|
2015-10-19 |
2017-04-27 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
SG10202004618TA
(en)
|
2015-11-19 |
2020-06-29 |
Incyte Corp |
Heterocyclic compounds as immunomodulators
|
|
EP3380471B8
(en)
*
|
2015-11-25 |
2022-01-19 |
Lieber Institute Inc. DBA Lieber Institute For Brain Development |
Tetrahydro-8h-pyrido[1,2-a]pyrazine-8-ones as comt inhibitors for the treatment of neurodegenerative disorders
|
|
CN105481812B
(zh)
*
|
2015-11-30 |
2020-04-21 |
重庆天奕恒化科技有限公司 |
一种5-苄氧基-4-氧代-4h-吡喃-2-羧酸的制备方法
|
|
MA44075A
(fr)
|
2015-12-17 |
2021-05-19 |
Incyte Corp |
Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1
|
|
AU2016379372A1
(en)
|
2015-12-22 |
2018-08-02 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
AR108396A1
(es)
|
2016-05-06 |
2018-08-15 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
WO2017205464A1
(en)
|
2016-05-26 |
2017-11-30 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
HUE060256T2
(hu)
|
2016-06-20 |
2023-02-28 |
Incyte Corp |
Heterociklusos vegyületek mint immunmodulátorok
|
|
EP3484866B1
(en)
|
2016-07-14 |
2022-09-07 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2018044783A1
(en)
|
2016-08-29 |
2018-03-08 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2018074390A1
(ja)
|
2016-10-17 |
2018-04-26 |
塩野義製薬株式会社 |
二環性含窒素複素環誘導体およびそれらを含有する医薬組成物
|
|
JP7101678B2
(ja)
|
2016-12-22 |
2022-07-15 |
インサイト・コーポレイション |
免疫調節剤としての複素環式化合物
|
|
US20180179202A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2018119221A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Pyridine derivatives as immunomodulators
|
|
ES2874756T3
(es)
|
2016-12-22 |
2021-11-05 |
Incyte Corp |
Derivados de triazolo[1,5-A]piridina como inmunomoduladores
|
|
LT3558990T
(lt)
|
2016-12-22 |
2022-12-27 |
Incyte Corporation |
Tetrahidroimidazo[4,5-c]piridino dariniai kaip pd-l1 internalizavimo induktoriai
|
|
BR112019020401A2
(pt)
*
|
2017-03-31 |
2020-04-22 |
Fujifilm Corp |
composto 4-piridona ou seu sal, e composição farmacêutica e formulação que inclui o mesmo
|
|
CN108191746B
(zh)
*
|
2018-02-02 |
2020-06-16 |
暨南大学 |
一种羟基吡啶酮类化合物及其制备方法与应用
|
|
SMT202500157T1
(it)
|
2018-03-30 |
2025-05-12 |
Incyte Corp |
Composti eterociclici come immunomodulatori
|
|
HUE061503T2
(hu)
|
2018-05-11 |
2023-07-28 |
Incyte Corp |
Tetrahidro-imidazo[4,5-C]piridin-származékok mint PD-L1 immunmodulátorok
|
|
EP3876939A4
(en)
|
2018-11-07 |
2022-08-10 |
Dana-Farber Cancer Institute, Inc. |
Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof
|
|
US12522583B2
(en)
|
2018-11-07 |
2026-01-13 |
Dana-Farber Cancer Institute, Inc. |
Benzimidazole derivatives and aza-benzimidazole derivatives as Janus kinase 2 inhibitors and uses thereof
|
|
EP3877371A4
(en)
|
2018-11-07 |
2022-07-27 |
Dana-Farber Cancer Institute, Inc. |
IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF
|
|
JP7665593B2
(ja)
|
2019-08-09 |
2025-04-21 |
インサイト・コーポレイション |
Ｐｄ－１／ｐｄ－ｌ１阻害剤の塩
|
|
PE20221038A1
(es)
|
2019-09-30 |
2022-06-17 |
Incyte Corp |
Compuestos de pirido[3,2-d] pirimidina como inmunomoduladores
|
|
CA3160131A1
(en)
|
2019-11-11 |
2021-05-20 |
Incyte Corporation |
Salts and crystalline forms of a pd-1/pd-l1 inhibitor
|
|
CN111170936B
(zh)
*
|
2020-01-19 |
2021-01-01 |
杭州泽德医药科技有限公司 |
3,4-二羟基-n-(1’-苄基-2’-羟乙基)-2-甲基吡啶氯化物及制备和应用
|
|
US11691963B2
(en)
|
2020-05-06 |
2023-07-04 |
Ajax Therapeutics, Inc. |
6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors
|
|
KR102377058B1
(ko)
|
2020-11-04 |
2022-03-22 |
경북대학교 산학협력단 |
니아스텔라 코리엔시스에서 유래한 카테콜 o-메틸 트렌스퍼라제 및 이의 변이체
|
|
TW202233615A
(zh)
|
2020-11-06 |
2022-09-01 |
美商英塞特公司 |
Ｐｄ—１／ｐｄ—ｌ１抑制劑之結晶形式
|
|
WO2022099018A1
(en)
|
2020-11-06 |
2022-05-12 |
Incyte Corporation |
Process of preparing a pd-1/pd-l1 inhibitor
|
|
CR20230230A
(es)
|
2020-11-06 |
2023-07-27 |
Incyte Corp |
Proceso para hacer un inhibidor de pd-1/pdl1 y sales y formas cristalinas del mismo
|
|
US12043632B2
(en)
|
2020-12-23 |
2024-07-23 |
Ajax Therapeutics, Inc. |
6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors
|
|
US20250276955A1
(en)
*
|
2021-07-19 |
2025-09-04 |
Baylor College Of Medicine |
Coronavirus main protease inhibitors and methods using same
|
|
WO2023086319A1
(en)
|
2021-11-09 |
2023-05-19 |
Ajax Therapeutics, Inc. |
6-he tero aryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors
|
|
US12162881B2
(en)
|
2021-11-09 |
2024-12-10 |
Ajax Therapeutics, Inc. |
Forms and compositions of inhibitors of JAK2
|
|
CN114716366B
(zh)
*
|
2022-04-13 |
2023-12-26 |
浙江大学 |
3-羟基吡啶-4-酮类衍生物及在抑制肾细胞铁死亡中的应用
|
|
CN116947812B
(zh)
*
|
2023-06-30 |
2025-09-02 |
南京红太阳医药研究院有限公司 |
一种艾司奥美拉唑镁降解杂质的制备方法
|
|
WO2025257687A1
(en)
*
|
2024-06-11 |
2025-12-18 |
Universidade Do Porto |
Hydroxypyridinone compounds as inhibitors of catechol-o-methyltransferase
|