JP2013513388A5 - - Google Patents
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- JP2013513388A5 JP2013513388A5 JP2012543304A JP2012543304A JP2013513388A5 JP 2013513388 A5 JP2013513388 A5 JP 2013513388A5 JP 2012543304 A JP2012543304 A JP 2012543304A JP 2012543304 A JP2012543304 A JP 2012543304A JP 2013513388 A5 JP2013513388 A5 JP 2013513388A5
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- human
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28525009P | 2009-12-10 | 2009-12-10 | |
| US61/285,250 | 2009-12-10 | ||
| PCT/US2010/059845 WO2011072204A1 (en) | 2009-12-10 | 2010-12-10 | Mice that make heavy chain antibodies |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015008099A Division JP6271450B2 (ja) | 2009-12-10 | 2015-01-19 | 重鎖抗体を作製するマウス |
| JP2015094069A Division JP6293702B2 (ja) | 2009-12-10 | 2015-05-01 | 重鎖抗体を作製するマウス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013513388A JP2013513388A (ja) | 2013-04-22 |
| JP2013513388A5 true JP2013513388A5 (enExample) | 2015-03-12 |
| JP5909449B2 JP5909449B2 (ja) | 2016-04-26 |
Family
ID=43534479
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543304A Active JP5909449B2 (ja) | 2009-12-10 | 2010-12-10 | 重鎖抗体を作製するマウス |
| JP2015008099A Active JP6271450B2 (ja) | 2009-12-10 | 2015-01-19 | 重鎖抗体を作製するマウス |
| JP2015094069A Active JP6293702B2 (ja) | 2009-12-10 | 2015-05-01 | 重鎖抗体を作製するマウス |
| JP2017106527A Active JP6615830B2 (ja) | 2009-12-10 | 2017-05-30 | 重鎖抗体を作製するマウス |
| JP2019088172A Withdrawn JP2019141095A (ja) | 2009-12-10 | 2019-05-08 | 重鎖抗体を作製するマウス |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015008099A Active JP6271450B2 (ja) | 2009-12-10 | 2015-01-19 | 重鎖抗体を作製するマウス |
| JP2015094069A Active JP6293702B2 (ja) | 2009-12-10 | 2015-05-01 | 重鎖抗体を作製するマウス |
| JP2017106527A Active JP6615830B2 (ja) | 2009-12-10 | 2017-05-30 | 重鎖抗体を作製するマウス |
| JP2019088172A Withdrawn JP2019141095A (ja) | 2009-12-10 | 2019-05-08 | 重鎖抗体を作製するマウス |
Country Status (24)
| Country | Link |
|---|---|
| US (9) | US8754287B2 (enExample) |
| EP (3) | EP2509409B1 (enExample) |
| JP (5) | JP5909449B2 (enExample) |
| KR (2) | KR101553244B1 (enExample) |
| CN (3) | CN104131035A (enExample) |
| AU (1) | AU2010328046C1 (enExample) |
| CA (1) | CA2782936C (enExample) |
| CY (2) | CY1118163T1 (enExample) |
| DK (2) | DK2509409T3 (enExample) |
| ES (2) | ES2595376T3 (enExample) |
| HR (1) | HRP20190820T1 (enExample) |
| HU (2) | HUE030208T2 (enExample) |
| IL (4) | IL220150A0 (enExample) |
| LT (2) | LT2509409T (enExample) |
| MY (2) | MY172472A (enExample) |
| PL (2) | PL2509409T3 (enExample) |
| PT (2) | PT2509409T (enExample) |
| RS (1) | RS58709B1 (enExample) |
| RU (1) | RU2603102C2 (enExample) |
| SG (2) | SG181477A1 (enExample) |
| SI (2) | SI2509409T1 (enExample) |
| SM (1) | SMT201900251T1 (enExample) |
| TR (1) | TR201906488T4 (enExample) |
| WO (1) | WO2011072204A1 (enExample) |
Families Citing this family (163)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1978032A3 (en) | 2004-07-22 | 2009-02-18 | Erasmus University Medical Center Rotterdam | Binding molecules |
| WO2010039900A2 (en) * | 2008-09-30 | 2010-04-08 | Aliva Biopharmaceuticals, Inc. | Non-human mammals for the production of chimeric antibodies |
| GB0905023D0 (en) | 2009-03-24 | 2009-05-06 | Univ Erasmus Medical Ct | Binding molecules |
| CN102638971B (zh) | 2009-07-08 | 2015-10-07 | 科马布有限公司 | 动物模型及治疗分子 |
| US9445581B2 (en) | 2012-03-28 | 2016-09-20 | Kymab Limited | Animal models and therapeutic molecules |
| DK2509409T3 (en) * | 2009-12-10 | 2016-11-14 | Regeneron Pharma | MICE, WHICH PRODUCES HEAVY CHAIN ANTIBODIES |
| US9796788B2 (en) | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| US20130045492A1 (en) | 2010-02-08 | 2013-02-21 | Regeneron Pharmaceuticals, Inc. | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain |
| HRP20151188T4 (hr) | 2010-02-08 | 2021-10-01 | Regeneron Pharmaceuticals, Inc. | Miš sa zajedničkim lakim lancem |
| PL3251503T3 (pl) | 2010-03-31 | 2024-07-08 | Ablexis, Llc | Modyfikacja myszy metodami inżynierii genetycznej w celu wytworzenia przeciwciał chimerycznych |
| US10793829B2 (en) | 2010-07-26 | 2020-10-06 | Trianni, Inc. | Transgenic mammals and methods of use thereof |
| RU2580017C2 (ru) | 2010-07-26 | 2016-04-10 | Трианни, Инк. | Трансгенные животные и способы применения |
| US10662256B2 (en) | 2010-07-26 | 2020-05-26 | Trianni, Inc. | Transgenic mammals and methods of use thereof |
| KR102306967B1 (ko) | 2010-08-02 | 2021-10-01 | 리제너론 파아마슈티컬스, 인크. | Ｖｌ 도메인을 포함하는 결합 단백질을 생성하는 마우스 |
| LT2738259T (lt) | 2011-02-25 | 2020-03-10 | Regeneron Pharmaceuticals, Inc. | Adam6 pelės |
| US20140056897A1 (en) * | 2011-03-10 | 2014-02-27 | Hco Antibody, Inc. | Bispecific three-chain antibody-like molecules |
| PT3865581T (pt) | 2011-08-05 | 2024-10-04 | Regeneron Pharma | Murganhos da cadeia leve universal humanizada |
| AU2012311286B2 (en) * | 2011-09-19 | 2018-07-26 | Kymab Limited | Antibodies, variable domains and chains tailored for human use |
| GB2501753A (en) * | 2012-05-04 | 2013-11-06 | Kymab Ltd | Human antibodies |
| WO2013045916A1 (en) * | 2011-09-26 | 2013-04-04 | Kymab Limited | Chimaeric surrogate light chains (slc) comprising human vpreb |
| KR20140082824A (ko) * | 2011-10-17 | 2014-07-02 | 리제너론 파아마슈티컬스, 인크. | 제한된 면역글로불린 중쇄 마우스 |
| CA2857645A1 (en) * | 2011-11-30 | 2013-06-06 | Wellstat Diagnostics, Llc | Assays, antibodies, immunogens and compositions related to 5-fu |
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