JP2013512889A5 - - Google Patents
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- Publication number
- JP2013512889A5 JP2013512889A5 JP2012541584A JP2012541584A JP2013512889A5 JP 2013512889 A5 JP2013512889 A5 JP 2013512889A5 JP 2012541584 A JP2012541584 A JP 2012541584A JP 2012541584 A JP2012541584 A JP 2012541584A JP 2013512889 A5 JP2013512889 A5 JP 2013512889A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- sheep
- difficile
- toxin
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0921288.7 | 2009-12-04 | ||
| GBGB0921288.7A GB0921288D0 (en) | 2009-12-04 | 2009-12-04 | Therapies for preventing or suppressing clostridium difficile infection |
| GBPCT/GB2010/050288 | 2010-02-19 | ||
| PCT/GB2010/050288 WO2010094970A1 (en) | 2009-02-20 | 2010-02-19 | Antibodies to clostridium difficile toxins |
| PCT/GB2010/052035 WO2011067616A1 (en) | 2009-12-04 | 2010-12-06 | Therapies for preventing or suppressing clostridium difficile infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013512889A JP2013512889A (ja) | 2013-04-18 |
| JP2013512889A5 true JP2013512889A5 (enExample) | 2014-01-30 |
| JP5877161B2 JP5877161B2 (ja) | 2016-03-02 |
Family
ID=41641956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012541584A Active JP5877161B2 (ja) | 2009-12-04 | 2010-12-06 | クロストリジウム・ディフィシル感染を予防または抑制するための治療法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8921529B2 (enExample) |
| EP (1) | EP2506877B1 (enExample) |
| JP (1) | JP5877161B2 (enExample) |
| CN (1) | CN102740889A (enExample) |
| BR (1) | BR112012013496A2 (enExample) |
| CA (1) | CA2782639C (enExample) |
| GB (1) | GB0921288D0 (enExample) |
| MY (1) | MY158712A (enExample) |
| SG (1) | SG181127A1 (enExample) |
| WO (1) | WO2011067616A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8709428B2 (en) | 2009-02-20 | 2014-04-29 | Health Protection Agency | Antibodies to Clostridium difficile toxins |
| GB0921288D0 (en) | 2009-12-04 | 2010-01-20 | Health Prot Agency | Therapies for preventing or suppressing clostridium difficile infection |
| CN103957931B (zh) | 2010-09-03 | 2017-10-24 | 瓦尔内瓦奥地利有限责任公司 | 艰难梭状芽胞杆菌毒素a和毒素b蛋白的分离多肽及其用途 |
| GB201016742D0 (en) * | 2010-10-05 | 2010-11-17 | Health Prot Agency | Clostridium difficile antigens |
| CN103619871B (zh) | 2011-04-22 | 2016-12-14 | 惠氏有限责任公司 | 涉及突变体难辨梭菌毒素的组合物及其方法 |
| SG11201400916XA (en) | 2011-08-22 | 2014-06-27 | Cangene Corp | Clostridium difficile antibodies |
| KR20140101835A (ko) | 2011-12-08 | 2014-08-20 | 노파르티스 아게 | 클로스트리듐 디피실레 톡신-기반 백신 |
| DE102011121237A1 (de) * | 2011-12-14 | 2013-06-20 | Universitätsklinikum Hamburg-Eppendorf | Einzeldomänen-Antikörper gegen Clostridium difficile Toxin CDTa |
| AR089797A1 (es) * | 2012-01-27 | 2014-09-17 | Merck Sharp & Dohme | Vacunas contra clostridum difficile que comprenden toxinas recombinantes |
| BR122016023101B1 (pt) | 2012-10-21 | 2022-03-22 | Pfizer Inc | Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile |
| WO2014135891A1 (en) | 2013-03-08 | 2014-09-12 | Cipla Limited | Pharmaceutical compositions for rectal administration |
| HK1213917A1 (zh) * | 2013-03-15 | 2016-07-15 | Sanofi Pasteur, Inc. | 類霉素、組合物及相關方法 |
| WO2014176276A1 (en) * | 2013-04-22 | 2014-10-30 | Board Of Regents Of The University Of Oklahoma | Clostridium difficile vaccine and methods of use |
| US9730994B2 (en) | 2013-06-14 | 2017-08-15 | Sanofi Pasteur, Inc. | Compositions and methods for immunizing against C. difficile |
| EP2957570B1 (en) * | 2014-06-20 | 2019-04-17 | Immunimed Inc. | Polyclonal antibodies against clostridium difficile and uses thereof |
| US10513552B2 (en) | 2014-06-20 | 2019-12-24 | Immunimed Inc. | Use of polyclonal antibodies against clostridium difficile for treatment of inflammatory bowel disease |
| CN106659799B (zh) * | 2014-07-25 | 2020-07-17 | 碧奥辛斯有限责任公司 | 用于制备针对因肠致病性细菌引起的感染的广谱疫苗的包含表达内置的多个表位的分子构建体的基本单元的糖缀合物疫苗 |
| EP3121272A1 (en) * | 2015-07-24 | 2017-01-25 | Zymetech ehf. | Novel fish trypsin isoforms and their use |
| US20190111001A1 (en) * | 2016-03-30 | 2019-04-18 | University Of Maryland, Baltimore | Microparticulate system for colonic drug delivery |
| GB201701404D0 (en) * | 2017-01-27 | 2017-03-15 | Micropharm Ltd | Therapies for treating inflammatory disorders |
| WO2021255690A2 (en) | 2020-06-19 | 2021-12-23 | Pfizer Inc. | Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof |
| GB202019817D0 (en) * | 2020-12-15 | 2021-01-27 | Univ Oxford Innovation Ltd | Ligand-binding polypeptides and uses thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS608225A (ja) | 1983-06-29 | 1985-01-17 | Kowa Co | 腸管吸収医薬組成物 |
| US5601823A (en) * | 1989-10-31 | 1997-02-11 | Ophidian Pharmaceuticals, Inc. | Avian antitoxins to clostridium difficle toxin A |
| EP0779819A1 (en) | 1994-09-06 | 1997-06-25 | Galagen Inc. | Therapeutic treatment of clostridium difficile associated diseases |
| AU709586B2 (en) * | 1994-10-24 | 1999-09-02 | Ophidian Pharmaceuticals, Inc. | Vaccine and antitoxin for treatment and prevention of C. difficile disease |
| US6096310A (en) | 1997-04-15 | 2000-08-01 | Bier; Milan | Oral immunotherapy of bacterial overgrowth |
| WO1998059053A1 (en) | 1997-06-20 | 1998-12-30 | Queen Mary & Westfield College | Immonogenic fragments of toxin a of clostridium difficile |
| EP2305303A3 (en) | 1997-10-20 | 2013-11-13 | Sanofi Pasteur Biologics Co. | Immunization against Clostridium difficile disease |
| US6969520B2 (en) | 1997-10-20 | 2005-11-29 | Acambis Inc. | Active immunization against clostridium difficile disease |
| US6074689A (en) | 1998-03-10 | 2000-06-13 | Immucell Corporation | Colonic delivery of protein or peptide compositions |
| US20020009429A1 (en) | 1999-01-29 | 2002-01-24 | Galagen, Inc. | Pharmaceutical composition comprising a selected antigen and candida species antigen and methods |
| US6673574B2 (en) * | 2000-11-30 | 2004-01-06 | Unigene Laboratories Inc. | Oral delivery of peptides using enzyme-cleavable membrane translocators |
| GB0205206D0 (en) | 2002-03-06 | 2002-04-17 | Oxoid Ltd | Synthetic peptides |
| US7226597B2 (en) | 2002-06-17 | 2007-06-05 | The Board Of Regents Of The University Of Oklahoma | Mutants of Clostridium difficile toxin B and methods of use |
| WO2004003145A2 (en) * | 2002-06-28 | 2004-01-08 | Nastech Pharmaceutical Company Inc. | Compositions and methods for modulating physiology of epithelial junctional adhesion molecules for enhanced mucosal delivery of therapeutic compounds |
| GB0309126D0 (en) | 2003-04-17 | 2003-05-28 | Neutec Pharma Plc | Clostridium difficile focussed antibodies |
| NZ548821A (en) * | 2004-02-06 | 2009-12-24 | Univ Massachusetts | Antibodies against clostridium difficile toxins and uses thereof |
| CN101001641A (zh) * | 2004-04-29 | 2007-07-18 | 葛兰素伊斯特拉齐瓦基森塔萨格勒布公司 | 用于治疗代谢性骨病的包含骨形态发生蛋白的口服制剂 |
| US20090087478A1 (en) | 2004-12-27 | 2009-04-02 | Progenics Pharmaceuticals (Nevada), Inc. | Orally Deliverable and Anti-Toxin Antibodies and Methods for Making and Using Them |
| US7794721B2 (en) | 2006-12-13 | 2010-09-14 | Simon Michael R | Synthesis of human secretory IgM and the treatment of clostridium difficile associated diseases herewith |
| CN101363867B (zh) | 2008-05-26 | 2012-12-19 | 北京庄笛浩禾生物医学科技有限公司 | 一种艰难梭菌a、b毒素胶体金检测试纸条及其制备方法 |
| US8709428B2 (en) | 2009-02-20 | 2014-04-29 | Health Protection Agency | Antibodies to Clostridium difficile toxins |
| GB0921288D0 (en) | 2009-12-04 | 2010-01-20 | Health Prot Agency | Therapies for preventing or suppressing clostridium difficile infection |
-
2009
- 2009-12-04 GB GBGB0921288.7A patent/GB0921288D0/en not_active Ceased
-
2010
- 2010-12-06 MY MYPI2012002466A patent/MY158712A/en unknown
- 2010-12-06 CN CN2010800537789A patent/CN102740889A/zh active Pending
- 2010-12-06 JP JP2012541584A patent/JP5877161B2/ja active Active
- 2010-12-06 WO PCT/GB2010/052035 patent/WO2011067616A1/en not_active Ceased
- 2010-12-06 SG SG2012039616A patent/SG181127A1/en unknown
- 2010-12-06 EP EP10787170.9A patent/EP2506877B1/en active Active
- 2010-12-06 CA CA2782639A patent/CA2782639C/en active Active
- 2010-12-06 US US13/513,555 patent/US8921529B2/en active Active
- 2010-12-06 BR BR112012013496A patent/BR112012013496A2/pt not_active IP Right Cessation
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