JP2013502918A - 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド - Google Patents
髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド Download PDFInfo
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- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 description 1
- 229960001661 ursodiol Drugs 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000010698 whale oil Substances 0.000 description 1
- 241000228158 x Triticosecale Species 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
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- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US23757609P | 2009-08-27 | 2009-08-27 | |
| US61/237,576 | 2009-08-27 | ||
| PCT/IB2010/002260 WO2011024072A2 (en) | 2009-08-27 | 2010-08-27 | Hybrid polypeptides including meningococcal fhbp sequences |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2015036548A Division JP2015110653A (ja) | 2009-08-27 | 2015-02-26 | 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド |
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| JP2013502918A5 JP2013502918A5 (enExample) | 2013-09-19 |
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| US (1) | US20110076300A1 (enExample) |
| EP (2) | EP3017828A1 (enExample) |
| JP (2) | JP2013502918A (enExample) |
| CN (2) | CN104650241A (enExample) |
| AU (1) | AU2010288240B2 (enExample) |
| BR (1) | BR112012004275A2 (enExample) |
| CA (1) | CA2772104A1 (enExample) |
| ES (1) | ES2562259T3 (enExample) |
| NZ (2) | NZ622048A (enExample) |
| WO (1) | WO2011024072A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0819633D0 (en) * | 2008-10-25 | 2008-12-03 | Isis Innovation | Composition |
| EA026401B1 (ru) | 2009-09-02 | 2017-04-28 | Новартис Аг | Иммуногенные композиции, содержащие модуляторы активности tlr |
| CA2784580A1 (en) | 2009-12-15 | 2011-07-14 | Novartis Ag | Homogeneous suspension of immunopotentiating compounds and uses thereof |
| SI3246044T2 (sl) | 2010-08-23 | 2024-06-28 | Wyeth Llc | Stabilne formulacije antigenov neisseria meningitidis RLP2086 |
| ES2458355T3 (es) | 2010-09-01 | 2014-05-05 | Novartis Ag | Adsorción de inmunopotenciadores sobre sales metálicas insolubles |
| PE20140173A1 (es) | 2010-09-10 | 2014-02-20 | Wyeth Llc | Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis |
| BR112013022397A2 (pt) | 2011-03-02 | 2017-09-26 | Derek OHagan | vacinas combinadas com doses menores de antígeno e/ou adjuvante |
| RU2014140336A (ru) | 2012-03-07 | 2016-04-27 | Новартис Аг | Иммунологически полезные соли аргинина |
| RU2014140521A (ru) | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| KR101716557B1 (ko) | 2012-03-09 | 2017-03-14 | 화이자 인코포레이티드 | 수막염균 조성물 및 이의 사용 방법 |
| CA2875391A1 (en) | 2012-07-27 | 2014-01-30 | Institut National De La Sante Et De La Recherche Medicale | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| RU2015106930A (ru) | 2012-09-06 | 2016-10-20 | Новартис Аг | Комбинированные вакцины с менингококком серогруппы в и к/д/с |
| JP6446377B2 (ja) | 2013-03-08 | 2018-12-26 | ファイザー・インク | 免疫原性融合ポリペプチド |
| MX369534B (es) | 2013-09-08 | 2019-11-11 | Pfizer | Composiciones de neisseria meningitidis y sus metodos. |
| KR20190049940A (ko) | 2015-02-19 | 2019-05-09 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
| WO2016184860A1 (en) * | 2015-05-18 | 2016-11-24 | Universita' Degli Studi Di Trento | Immunogenic compositions containing bacterial outer membrane vesicles and therapeutic uses thereof |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| MX2019002489A (es) | 2016-09-02 | 2019-10-21 | Sanofi Pasteur Inc | Vacuna contra neisseria meningitidis. |
| BR112019014397A2 (pt) | 2017-01-31 | 2020-02-11 | Pfizer Inc. | Composições de neisseria meningitidis e métodos das mesmas |
| CN107961369B (zh) * | 2017-03-22 | 2020-08-11 | 武汉博沃生物科技有限公司 | 多价脑膜炎球菌缀合疫苗及其制备方法 |
| GB201809622D0 (en) * | 2018-06-12 | 2018-07-25 | Evox Therapeutics Ltd | Engineering extracellular vesicles for affinity purification |
| MX2022003682A (es) | 2019-09-27 | 2022-04-25 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas. |
| IN202321021121A (enExample) * | 2023-03-24 | 2024-04-19 |
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2010
- 2010-08-27 JP JP2012526142A patent/JP2013502918A/ja not_active Ceased
- 2010-08-27 US US12/870,718 patent/US20110076300A1/en not_active Abandoned
- 2010-08-27 BR BR112012004275A patent/BR112012004275A2/pt not_active IP Right Cessation
- 2010-08-27 ES ES10765842.9T patent/ES2562259T3/es active Active
- 2010-08-27 WO PCT/IB2010/002260 patent/WO2011024072A2/en not_active Ceased
- 2010-08-27 EP EP15193267.0A patent/EP3017828A1/en not_active Withdrawn
- 2010-08-27 NZ NZ622048A patent/NZ622048A/en not_active IP Right Cessation
- 2010-08-27 CN CN201510008912.8A patent/CN104650241A/zh active Pending
- 2010-08-27 AU AU2010288240A patent/AU2010288240B2/en not_active Ceased
- 2010-08-27 CN CN201080047951.4A patent/CN102596240B/zh not_active Expired - Fee Related
- 2010-08-27 NZ NZ598458A patent/NZ598458A/en not_active IP Right Cessation
- 2010-08-27 EP EP10765842.9A patent/EP2470204B1/en not_active Not-in-force
- 2010-08-27 CA CA2772104A patent/CA2772104A1/en not_active Abandoned
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| JP2006512402A (ja) * | 2002-10-11 | 2006-04-13 | カイロン ソチエタ ア レスポンサビリタ リミタータ | 高毒性髄膜炎菌系統に対する広範な防御のためのポリペプチド−ワクチン |
| JP2006521782A (ja) * | 2002-11-22 | 2006-09-28 | カイロン ソチエタ ア レスポンサビリタ リミタータ | 髄膜炎菌タンパク質ｎｍｂ１８７０の複数の改変体 |
| WO2007060548A2 (en) * | 2005-11-25 | 2007-05-31 | Novartis Vaccines And Diagnostics Srl | Chimeric, hybrid and tandem polypeptides of meningococcal nmb1870 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010288240B2 (en) | 2014-03-27 |
| WO2011024072A3 (en) | 2011-06-09 |
| NZ598458A (en) | 2014-03-28 |
| EP2470204B1 (en) | 2015-12-16 |
| WO2011024072A2 (en) | 2011-03-03 |
| EP2470204A2 (en) | 2012-07-04 |
| AU2010288240A1 (en) | 2012-03-22 |
| JP2015110653A (ja) | 2015-06-18 |
| US20110076300A1 (en) | 2011-03-31 |
| BR112012004275A2 (pt) | 2016-11-16 |
| CN104650241A (zh) | 2015-05-27 |
| ES2562259T3 (es) | 2016-03-03 |
| CN102596240B (zh) | 2015-02-04 |
| EP3017828A1 (en) | 2016-05-11 |
| CN102596240A (zh) | 2012-07-18 |
| CA2772104A1 (en) | 2011-03-03 |
| NZ622048A (en) | 2015-10-30 |
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