AU2010288240B2 - Hybrid polypeptides including meningococcal fHBP sequences - Google Patents

Hybrid polypeptides including meningococcal fHBP sequences Download PDF

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Publication number
AU2010288240B2
AU2010288240B2 AU2010288240A AU2010288240A AU2010288240B2 AU 2010288240 B2 AU2010288240 B2 AU 2010288240B2 AU 2010288240 A AU2010288240 A AU 2010288240A AU 2010288240 A AU2010288240 A AU 2010288240A AU 2010288240 B2 AU2010288240 B2 AU 2010288240B2
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AU
Australia
Prior art keywords
amino acid
seq
acid sequence
polypeptide
immunogenic
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Ceased
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AU2010288240A
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AU2010288240A1 (en
Inventor
Maria Arico
Marzia Monica Giuliani
Mariagrazia Pizza
Rino Rappuoli
Maria Scarselli
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Novartis AG
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Novartis AG
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Priority to AU2013202472A priority Critical patent/AU2013202472A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2010288240A 2009-08-27 2010-08-27 Hybrid polypeptides including meningococcal fHBP sequences Ceased AU2010288240B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013202472A AU2013202472A1 (en) 2009-08-27 2013-04-04 Hybrid polypeptides including meningococcal fHBP sequences

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23757609P 2009-08-27 2009-08-27
US61/237,576 2009-08-27
PCT/IB2010/002260 WO2011024072A2 (en) 2009-08-27 2010-08-27 Hybrid polypeptides including meningococcal fhbp sequences

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013202472A Division AU2013202472A1 (en) 2009-08-27 2013-04-04 Hybrid polypeptides including meningococcal fHBP sequences

Publications (2)

Publication Number Publication Date
AU2010288240A1 AU2010288240A1 (en) 2012-03-22
AU2010288240B2 true AU2010288240B2 (en) 2014-03-27

Family

ID=43428588

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010288240A Ceased AU2010288240B2 (en) 2009-08-27 2010-08-27 Hybrid polypeptides including meningococcal fHBP sequences

Country Status (10)

Country Link
US (1) US20110076300A1 (enExample)
EP (2) EP3017828A1 (enExample)
JP (2) JP2013502918A (enExample)
CN (2) CN102596240B (enExample)
AU (1) AU2010288240B2 (enExample)
BR (1) BR112012004275A2 (enExample)
CA (1) CA2772104A1 (enExample)
ES (1) ES2562259T3 (enExample)
NZ (2) NZ622048A (enExample)
WO (1) WO2011024072A2 (enExample)

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DK2608805T4 (da) 2010-08-23 2025-06-30 Wyeth Llc STABILE FORMULERINGER AF NEISSERIA MENINGITIDIS rLP2086 ANTIGENER
CN105999275A (zh) 2010-09-01 2016-10-12 诺华有限公司 免疫增强剂吸附不溶性金属离子
RU2546873C2 (ru) 2010-09-10 2015-04-10 УАЙТ ЭлЭлСи Нелипидизированные варианты антигенов neisseria meningitidis orf2086
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US9320748B2 (en) 2012-03-07 2016-04-26 Novartis Ag Immunologically useful arginine salts
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SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
PE20190458A1 (es) * 2012-03-09 2019-04-01 Pfizer Composiciones de neisseria meningitidis y metodos de las mismas
CA2875391A1 (en) 2012-07-27 2014-01-30 Institut National De La Sante Et De La Recherche Medicale Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
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WO2014136064A2 (en) 2013-03-08 2014-09-12 Pfizer Inc. Immunogenic fusion polypeptides
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MX391027B (es) 2015-02-19 2025-03-21 Pfizer Composiciones de neisseria meningitidis y metodos de la misma.
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GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
RS65362B1 (sr) 2016-09-02 2024-04-30 Sanofi Pasteur Inc Vakcina protiv neisseria meningitidis
PE20191107A1 (es) 2017-01-31 2019-08-26 Pfizer Composiciones de neisseria meningitidis y metodos respectivos
CN107961370B (zh) * 2017-03-22 2020-08-11 武汉博沃生物科技有限公司 多价肺炎球菌缀合疫苗及其制备方法
GB201809622D0 (en) * 2018-06-12 2018-07-25 Evox Therapeutics Ltd Engineering extracellular vesicles for affinity purification
CN115605222A (zh) 2019-09-27 2023-01-13 辉瑞公司（Us） 脑膜炎奈瑟氏菌组合物及其方法
IN202321021121A (enExample) * 2023-03-24 2024-04-19

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