AU2010288240B2 - Hybrid polypeptides including meningococcal fHBP sequences - Google Patents

Hybrid polypeptides including meningococcal fHBP sequences Download PDF

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Publication number
AU2010288240B2
AU2010288240B2 AU2010288240A AU2010288240A AU2010288240B2 AU 2010288240 B2 AU2010288240 B2 AU 2010288240B2 AU 2010288240 A AU2010288240 A AU 2010288240A AU 2010288240 A AU2010288240 A AU 2010288240A AU 2010288240 B2 AU2010288240 B2 AU 2010288240B2
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AU
Australia
Prior art keywords
amino acid
seq
acid sequence
polypeptide
immunogenic
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Ceased
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AU2010288240A
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AU2010288240A1 (en
Inventor
Maria Arico
Marzia Monica Giuliani
Mariagrazia Pizza
Rino Rappuoli
Maria Scarselli
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Novartis AG
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Novartis AG
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Priority to AU2013202472A priority Critical patent/AU2013202472A1/en
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Ceased legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2010288240A 2009-08-27 2010-08-27 Hybrid polypeptides including meningococcal fHBP sequences Ceased AU2010288240B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013202472A AU2013202472A1 (en) 2009-08-27 2013-04-04 Hybrid polypeptides including meningococcal fHBP sequences

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23757609P 2009-08-27 2009-08-27
US61/237,576 2009-08-27
PCT/IB2010/002260 WO2011024072A2 (en) 2009-08-27 2010-08-27 Hybrid polypeptides including meningococcal fhbp sequences

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013202472A Division AU2013202472A1 (en) 2009-08-27 2013-04-04 Hybrid polypeptides including meningococcal fHBP sequences

Publications (2)

Publication Number Publication Date
AU2010288240A1 AU2010288240A1 (en) 2012-03-22
AU2010288240B2 true AU2010288240B2 (en) 2014-03-27

Family

ID=43428588

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010288240A Ceased AU2010288240B2 (en) 2009-08-27 2010-08-27 Hybrid polypeptides including meningococcal fHBP sequences

Country Status (10)

Country Link
US (1) US20110076300A1 (enExample)
EP (2) EP3017828A1 (enExample)
JP (2) JP2013502918A (enExample)
CN (2) CN104650241A (enExample)
AU (1) AU2010288240B2 (enExample)
BR (1) BR112012004275A2 (enExample)
CA (1) CA2772104A1 (enExample)
ES (1) ES2562259T3 (enExample)
NZ (2) NZ598458A (enExample)
WO (1) WO2011024072A2 (enExample)

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AU2011295853A1 (en) 2010-09-01 2013-04-04 Irm Llc Adsorption of immunopotentiators to insoluble metal salts
EP3056212B1 (en) 2010-09-10 2019-04-03 Wyeth LLC Non-lipidated variants of neisseria meningitidis orf2086 antigens
KR20140026392A (ko) 2011-03-02 2014-03-05 노파르티스 아게 저용량의 항원 및/또는 보조제를 갖는 조합 백신
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US9375471B2 (en) 2012-03-08 2016-06-28 Glaxosmithkline Biologicals Sa Adjuvanted formulations of booster vaccines
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
MY167723A (en) * 2012-03-09 2018-09-21 Pfizer Neisseria meningitidis compositions and methods thereof
HK1205138A1 (en) 2012-07-27 2015-12-11 Institut National De La Santé Et De La Recherche Médicale (Inserm) Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
CN104602705A (zh) 2012-09-06 2015-05-06 诺华股份有限公司 血清组b脑膜炎球菌和d/t/p的联合疫苗
JP6446377B2 (ja) 2013-03-08 2018-12-26 ファイザー・インク 免疫原性融合ポリペプチド
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AU2016262823A1 (en) * 2015-05-18 2017-12-07 Universita' Degli Studi Di Trento Immunogenic compositions containing bacterial outer membrane vesicles and therapeutic uses thereof
GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
PH12019500399B1 (en) 2016-09-02 2024-05-15 Sanofi Pasteur Inc Neisseria meningitidis vaccine
CN110234658B (zh) 2017-01-31 2024-03-12 辉瑞大药厂 脑膜炎奈瑟菌组合物及其使用方法
CN107961370B (zh) * 2017-03-22 2020-08-11 武汉博沃生物科技有限公司 多价肺炎球菌缀合疫苗及其制备方法
GB201809622D0 (en) * 2018-06-12 2018-07-25 Evox Therapeutics Ltd Engineering extracellular vesicles for affinity purification
AU2020355401B2 (en) 2019-09-27 2025-03-27 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
IN202321021121A (enExample) * 2023-03-24 2024-04-19

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