JP2013126996A5 - - Google Patents
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- JP2013126996A5 JP2013126996A5 JP2013027633A JP2013027633A JP2013126996A5 JP 2013126996 A5 JP2013126996 A5 JP 2013126996A5 JP 2013027633 A JP2013027633 A JP 2013027633A JP 2013027633 A JP2013027633 A JP 2013027633A JP 2013126996 A5 JP2013126996 A5 JP 2013126996A5
- Authority
- JP
- Japan
- Prior art keywords
- mir
- usa
- cells
- dilution
- differentiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74954405P | 2005-12-12 | 2005-12-12 | |
| US60/749,544 | 2005-12-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545718A Division JP2009519339A (ja) | 2005-12-12 | 2006-12-12 | 筋細胞増殖及び分化を調節するマイクロrna |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013126996A JP2013126996A (ja) | 2013-06-27 |
| JP2013126996A5 true JP2013126996A5 (enExample) | 2014-01-30 |
| JP5796027B2 JP5796027B2 (ja) | 2015-10-21 |
Family
ID=38163464
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545718A Pending JP2009519339A (ja) | 2005-12-12 | 2006-12-12 | 筋細胞増殖及び分化を調節するマイクロrna |
| JP2013027633A Expired - Fee Related JP5796027B2 (ja) | 2005-12-12 | 2013-02-15 | 筋細胞増殖及び分化を調節するマイクロrna |
| JP2013253829A Expired - Fee Related JP5740460B2 (ja) | 2005-12-12 | 2013-12-09 | 筋細胞増殖及び分化を調節するマイクロrna |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545718A Pending JP2009519339A (ja) | 2005-12-12 | 2006-12-12 | 筋細胞増殖及び分化を調節するマイクロrna |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013253829A Expired - Fee Related JP5740460B2 (ja) | 2005-12-12 | 2013-12-09 | 筋細胞増殖及び分化を調節するマイクロrna |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8431542B2 (enExample) |
| EP (3) | EP2497827A1 (enExample) |
| JP (3) | JP2009519339A (enExample) |
| KR (2) | KR20140130562A (enExample) |
| CN (2) | CN104027818A (enExample) |
| AU (1) | AU2006326517B2 (enExample) |
| BR (1) | BRPI0619755A2 (enExample) |
| CA (2) | CA2634046A1 (enExample) |
| DK (1) | DK1969125T3 (enExample) |
| ES (1) | ES2387250T3 (enExample) |
| NZ (3) | NZ569738A (enExample) |
| PL (1) | PL1969125T3 (enExample) |
| PT (1) | PT1969125E (enExample) |
| WO (1) | WO2007070483A2 (enExample) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2603881A1 (en) | 2005-04-04 | 2006-10-12 | The Board Of Regents Of The University Of Texas System | Micro-rna's that regulate muscle cells |
| EP2497827A1 (en) | 2005-12-12 | 2012-09-12 | University Of North Carolina At Chapel Hill | Micro-RNAs that regulate muscle cell proliferation and differentiation |
| AU2007281261B2 (en) | 2006-08-01 | 2013-03-21 | Board Of Regents Of The University Of Texas System | Identification of a micro-RNA that activates expression of beta-myosin heavy chain |
| GB2440782A (en) | 2006-08-04 | 2008-02-13 | Cesare Peschle | Uses and compositions comprising miRNAs |
| WO2008017473A2 (en) | 2006-08-08 | 2008-02-14 | Gunther Hartmann | Structure and use of 5' phosphate oligonucleotides |
| WO2009006450A1 (en) * | 2007-06-29 | 2009-01-08 | Boston Biomedical, Inc. | Bacteria-mediated gene modulation via microrna machinery |
| AU2008283794B2 (en) | 2007-07-31 | 2014-03-20 | Board Of Regents, The University Of Texas System | Micro-RNAs that control myosin expression and myofiber identity |
| NZ583024A (en) | 2007-07-31 | 2012-04-27 | Regents The Univeristy Of Texas System Board Of | An agonist of miR-29a, miR-29b or miR-29c that prevents tissue fibrosis and uses thereof |
| EP2257625A2 (en) * | 2008-02-21 | 2010-12-08 | The Board of Regents of The University of Texas System | Micro-rnas that modulate smooth muscle proliferation and differentiation and uses thereof |
| WO2009117418A2 (en) | 2008-03-17 | 2009-09-24 | The Board Of Regents Of The University Of Texas System | Identification of micro-rnas involved in neuromuscular synapse maintenance and regeneration |
| US9738680B2 (en) | 2008-05-21 | 2017-08-22 | Rheinische Friedrich-Wilhelms-Universität Bonn | 5′ triphosphate oligonucleotide with blunt end and uses thereof |
| AU2009257663B2 (en) | 2008-06-09 | 2014-06-26 | New York Medical College | Compositions comprising cardiac stem cells overexpressing specific microRNA and methods of their use in repairing damaged myocardium |
| GB0811715D0 (en) * | 2008-06-26 | 2008-07-30 | Angeletti P Ist Richerche Bio | Therapeutic agents |
| CA2751489A1 (en) | 2009-02-04 | 2010-08-12 | Board Of Regents, The University Of Texas System | Dual targeting of mir-208 and mir-499 in the treatment of cardiac disorders |
| CA2761106C (en) | 2009-05-05 | 2019-01-15 | Miragen Therapeutics | Lipophilic polynucleotide conjugates |
| EP2435570A1 (en) * | 2009-05-25 | 2012-04-04 | Carola Ponzetto | Differentiation therapy for sarcomas |
| WO2011105556A1 (ja) * | 2010-02-26 | 2011-09-01 | 独立行政法人国立精神・神経医療研究センター | 筋原性疾患検出用マーカー及びそれを用いた検出方法 |
| CN103108953B (zh) * | 2010-04-08 | 2015-04-08 | 京都府公立大学法人 | 使用来自体液的样本检测横纹肌肉瘤的方法 |
| WO2012006577A2 (en) | 2010-07-08 | 2012-01-12 | Duke University | Direct reprogramming of cells to cardiac myocyte fate |
| KR101235256B1 (ko) * | 2010-09-13 | 2013-02-21 | 서울대학교산학협력단 | miRNA를 타겟으로 한 신경퇴행성 질환 치료 |
| EP2635681B8 (en) | 2010-11-05 | 2017-10-04 | Miragen Therapeutics, Inc. | Base modified oligonucleotides |
| WO2012065024A1 (en) * | 2010-11-11 | 2012-05-18 | University Of Miami | Compositions, cells, kits and methods for autologous stem cell therapy |
| AR084319A1 (es) | 2010-12-15 | 2013-05-08 | Miragen Therapeutics | INHIBIDORES DE microARN (miARN O miR) QUE COMPRENDEN NUCLEOTIDOS BLOQUEADOS |
| EP2508530A1 (en) | 2011-03-28 | 2012-10-10 | Rheinische Friedrich-Wilhelms-Universität Bonn | Purification of triphosphorylated oligonucleotides using capture tags |
| EP2707485B1 (en) * | 2011-05-09 | 2016-12-14 | The University Court of The University Of Glasgow | Methods of modulating micrornas in the treatment of pulmonary arterial hypertension |
| CA2840222A1 (en) * | 2011-07-01 | 2013-01-10 | Board Of Regents, The University Of Texas System | Compositions and methods for treating skeletal myopathy |
| WO2013007874A1 (en) * | 2011-07-12 | 2013-01-17 | Mart Saarma | A transgenic animal comprising a deletion or functional deletion of the 3'utr of an endogenous gene. |
| US9018188B2 (en) | 2011-09-13 | 2015-04-28 | Ottawa Hospital Research Institute | MicroRNA inhibitors |
| CA2850223A1 (en) * | 2011-10-06 | 2013-04-11 | Eva Van Rooij | Control of whole body energy homeostasis by microrna regulation |
| CN104685056A (zh) | 2012-06-21 | 2015-06-03 | 米拉根医疗股份有限公司 | 包含锁核酸基序的基于寡核苷酸的抑制剂 |
| EP2712870A1 (en) | 2012-09-27 | 2014-04-02 | Rheinische Friedrich-Wilhelms-Universität Bonn | Novel RIG-I ligands and methods for producing them |
| CA2902623A1 (en) | 2013-03-15 | 2014-09-25 | MiRagen Therapeutics, Inc. | Locked nucleic acid inhibitor of mir-145 and uses thereof |
| CA2902571A1 (en) | 2013-03-15 | 2014-09-18 | MiRagen Therapeutics, Inc. | Bridged bicyclic nucleosides |
| US9624471B2 (en) | 2013-06-12 | 2017-04-18 | University Of Washington Through Its Center For Commercialization | Methods for maturing cardiomyocytes and uses thereof |
| CN103710387B (zh) * | 2013-12-25 | 2015-10-14 | 天津农学院 | 一种促进牛骨骼肌卫星细胞体外增殖的方法 |
| JP6566536B2 (ja) * | 2014-06-16 | 2019-08-28 | 国立大学法人山口大学 | フォワードプライマー |
| CN104498497A (zh) * | 2014-12-10 | 2015-04-08 | 山东农业大学 | 一种与奶山羊乳腺上皮细胞凋亡相关的miRNA及其在奶山羊育种中的应用 |
| WO2016114354A1 (ja) | 2015-01-14 | 2016-07-21 | 国立大学法人京都大学 | 骨格筋前駆細胞の選択方法 |
| JP2018503646A (ja) | 2015-01-20 | 2018-02-08 | ミラゲン セラピューティクス, インコーポレイテッド | miR−92阻害剤およびその使用 |
| CN104877960B (zh) * | 2015-06-01 | 2017-09-19 | 东北农业大学 | miR‑2400显著促进牛骨骼肌卫星细胞增殖的生物功能 |
| ES2986046T3 (es) | 2016-03-07 | 2024-11-08 | Us Health | MicroARN y métodos de su uso |
| CN105713972A (zh) * | 2016-03-16 | 2016-06-29 | 上海中医药大学 | miRNA在制备药物性心脏病生物标志物中的用途 |
| CN106399473B (zh) * | 2016-08-23 | 2019-12-06 | 南京大学 | 检测和评价力量训练效果的miRNA标志物或其组合及其应用 |
| US10934543B2 (en) | 2016-10-13 | 2021-03-02 | National Center Of Neurology And Psychiatry | Inducer of muscle differentiation |
| US10626395B2 (en) | 2016-10-27 | 2020-04-21 | The General Hospital Corporation | Therapeutic targeting of a microRNA to treat Duchenne muscular dystrophy |
| CN108324946B (zh) * | 2017-01-20 | 2022-02-18 | 上海市东方医院 | miRNA708、和/或301簇的微小RNA在改善心脏功能方面的应用 |
| CN107096030A (zh) * | 2017-03-20 | 2017-08-29 | 天津农学院 | 一种利用miR‑143抑制剂延缓小鼠失神经后肌肉萎缩的方法 |
| WO2018187523A2 (en) * | 2017-04-05 | 2018-10-11 | University Of Cincinnati | Promotion of cardiomyocyte proliferation and regenerative treatment of the heart by inhibition of microrna-128 |
| WO2019035690A1 (ko) * | 2017-08-18 | 2019-02-21 | 서울대학교병원 | 근육 질환 및 신경근육 질환 예방, 치료 또는 진단을 위한 miR-18b의 용도 |
| KR102177130B1 (ko) | 2017-08-18 | 2020-11-10 | (주)큐라미스 | 근육 질환 및 신경근육 질환 예방, 치료 또는 진단을 위한 miR-18b의 용도 |
| CN111629738A (zh) * | 2017-12-08 | 2020-09-04 | 华盛顿大学 | 检测和促进心磷脂重塑和心肌细胞成熟的方法和组合物以及治疗线粒体功能障碍的相关方法 |
| EP3765619B1 (en) * | 2018-03-14 | 2024-10-09 | Beth Israel Deaconess Medical Center | Inhibitors of micro-rna 22 |
| CN108690846A (zh) * | 2018-04-17 | 2018-10-23 | 上海大学 | 抑制MiR-29b基因表达的应用 |
| CN108823209B (zh) * | 2018-07-18 | 2021-04-09 | 华中农业大学 | 骨骼肌特异性启动子及应用 |
| CA3111076A1 (en) | 2018-08-30 | 2020-03-05 | Tenaya Therapeutics, Inc. | Cardiac cell reprogramming with myocardin and ascl1 |
| CN111041052B (zh) * | 2019-12-30 | 2021-05-28 | 嘉兴学院 | mir-206在抑制猪脂肪细胞内的甘油三酯生成以及瘦肉猪育种中的应用 |
| KR20220149590A (ko) * | 2020-03-02 | 2022-11-08 | 테나야 테라퓨틱스, 인코포레이티드 | 심근세포-발현 마이크로rna에 의한 유전자 벡터 제어 |
| BR112022019889A2 (pt) | 2020-04-02 | 2023-03-07 | Mirecule Inc | Inibição direcionada com o uso de oligonucleotídeos modificados geneticamente |
| CN112266912A (zh) * | 2020-10-22 | 2021-01-26 | 上海大学 | 靶向miR-29b的gRNA、AAV8-CRISPR/Cas9系统及其应用 |
| WO2023034966A1 (en) * | 2021-09-03 | 2023-03-09 | The University Of North Carolina At Chapel Hill | Compositions and methods of using the same for treating disorders associated with thymosin βeta 4 |
| CN114480672B (zh) * | 2022-02-22 | 2023-08-15 | 青岛农业大学 | 一种通过miR-145筛选高产肉率碱地黑牛的方法 |
| CN114748497B (zh) * | 2022-04-27 | 2024-10-18 | 广州市妇女儿童医疗中心 | 一种调控子宫肌收缩的miRNA分子miR-206及其应用 |
| CN115181722B (zh) * | 2022-08-30 | 2024-06-11 | 江苏农牧科技职业学院 | 一种鹅骨骼肌卫星细胞的体外分离和培养方法 |
| CN117511884B (zh) * | 2023-12-06 | 2024-06-11 | 中国农业科学院兰州畜牧与兽药研究所 | Rtl1在抑制牦牛成肌细胞分化中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7803782B2 (en) * | 2003-05-28 | 2010-09-28 | Roche Madison Inc. | Intravenous delivery of polynucleotides to cells in mammalian limb |
| US20050124566A1 (en) * | 2001-05-18 | 2005-06-09 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA) |
| EP2428568B1 (en) * | 2001-09-28 | 2018-04-25 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Microrna molecules |
| US7781415B2 (en) * | 2003-02-07 | 2010-08-24 | Roche Madison Inc. | Process for delivering sirna to cardiac muscle tissue |
| KR20050115231A (ko) * | 2003-02-10 | 2005-12-07 | 내셔날 인스티튜트 오브 어드밴스드 인더스트리얼 사이언스 앤드 테크놀로지 | 포유동물 세포의 조절 |
| SE0300500L (sv) * | 2003-02-26 | 2003-11-18 | Scania Cv Publ | Kraftöverföring med från en huvudväxel skild rangeväxel |
| EP2808389A1 (en) * | 2004-11-12 | 2014-12-03 | Asuragen, Inc. | Methods and compositions involving MIRNA and MIRNA inhibitor molecules |
| CA2603881A1 (en) | 2005-04-04 | 2006-10-12 | The Board Of Regents Of The University Of Texas System | Micro-rna's that regulate muscle cells |
| US7338670B2 (en) | 2005-04-14 | 2008-03-04 | Duke University | Use of an agent that restores tissue perfusion and oxygenation |
| EP2497827A1 (en) | 2005-12-12 | 2012-09-12 | University Of North Carolina At Chapel Hill | Micro-RNAs that regulate muscle cell proliferation and differentiation |
-
2006
- 2006-12-12 EP EP12166173A patent/EP2497827A1/en not_active Withdrawn
- 2006-12-12 CA CA002634046A patent/CA2634046A1/en not_active Abandoned
- 2006-12-12 WO PCT/US2006/047255 patent/WO2007070483A2/en not_active Ceased
- 2006-12-12 US US12/086,109 patent/US8431542B2/en not_active Expired - Fee Related
- 2006-12-12 PT PT06845222T patent/PT1969125E/pt unknown
- 2006-12-12 CA CA2903764A patent/CA2903764A1/en not_active Abandoned
- 2006-12-12 NZ NZ569738A patent/NZ569738A/en not_active IP Right Cessation
- 2006-12-12 BR BRPI0619755-8A patent/BRPI0619755A2/pt not_active IP Right Cessation
- 2006-12-12 EP EP13177425.9A patent/EP2671949A1/en not_active Withdrawn
- 2006-12-12 DK DK06845222.6T patent/DK1969125T3/da active
- 2006-12-12 KR KR1020147028814A patent/KR20140130562A/ko not_active Ceased
- 2006-12-12 AU AU2006326517A patent/AU2006326517B2/en not_active Ceased
- 2006-12-12 NZ NZ602571A patent/NZ602571A/en not_active IP Right Cessation
- 2006-12-12 KR KR1020087017004A patent/KR101485071B1/ko not_active Expired - Fee Related
- 2006-12-12 JP JP2008545718A patent/JP2009519339A/ja active Pending
- 2006-12-12 ES ES06845222T patent/ES2387250T3/es active Active
- 2006-12-12 CN CN201410112733.4A patent/CN104027818A/zh active Pending
- 2006-12-12 NZ NZ593688A patent/NZ593688A/xx not_active IP Right Cessation
- 2006-12-12 PL PL06845222T patent/PL1969125T3/pl unknown
- 2006-12-12 CN CN200680052681.XA patent/CN101448942B/zh not_active Expired - Fee Related
- 2006-12-12 EP EP06845222A patent/EP1969125B1/en active Active
-
2013
- 2013-02-15 JP JP2013027633A patent/JP5796027B2/ja not_active Expired - Fee Related
- 2013-03-08 US US13/791,736 patent/US20130225658A1/en not_active Abandoned
- 2013-03-08 US US13/791,309 patent/US9072764B2/en not_active Expired - Fee Related
- 2013-12-09 JP JP2013253829A patent/JP5740460B2/ja not_active Expired - Fee Related
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