JP2013010803A5 - - Google Patents
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- Publication number
- JP2013010803A5 JP2013010803A5 JP2012230662A JP2012230662A JP2013010803A5 JP 2013010803 A5 JP2013010803 A5 JP 2013010803A5 JP 2012230662 A JP2012230662 A JP 2012230662A JP 2012230662 A JP2012230662 A JP 2012230662A JP 2013010803 A5 JP2013010803 A5 JP 2013010803A5
- Authority
- JP
- Japan
- Prior art keywords
- tablet
- binding polymer
- phosphate
- low
- hardness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 claims 5
- 102000006335 Phosphate-Binding Proteins Human genes 0.000 claims 4
- 108010058514 Phosphate-Binding Proteins Proteins 0.000 claims 4
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 claims 4
- 229920002678 cellulose Polymers 0.000 claims 3
- 239000001913 cellulose Substances 0.000 claims 3
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 claims 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- 238000004132 cross linking Methods 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 229920000083 poly(allylamine) Polymers 0.000 claims 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
- -1 hydroxypropoxyl group Chemical group 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 239000007916 tablet composition Substances 0.000 claims 1
- 239000012085 test solution Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
- 239000013585 weight reducing agent Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012230662A JP5681156B2 (ja) | 1997-04-04 | 2012-10-18 | リン酸結合性ポリマー製剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8658197 | 1997-04-04 | ||
| JP1997086581 | 1997-04-04 | ||
| JP2012230662A JP5681156B2 (ja) | 1997-04-04 | 2012-10-18 | リン酸結合性ポリマー製剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009118371A Division JP2009173687A (ja) | 1997-04-04 | 2009-05-15 | リン酸結合性ポリマー製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013010803A JP2013010803A (ja) | 2013-01-17 |
| JP2013010803A5 true JP2013010803A5 (enExample) | 2013-03-07 |
| JP5681156B2 JP5681156B2 (ja) | 2015-03-04 |
Family
ID=13890981
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009118371A Withdrawn JP2009173687A (ja) | 1997-04-04 | 2009-05-15 | リン酸結合性ポリマー製剤 |
| JP2012230662A Expired - Fee Related JP5681156B2 (ja) | 1997-04-04 | 2012-10-18 | リン酸結合性ポリマー製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009118371A Withdrawn JP2009173687A (ja) | 1997-04-04 | 2009-05-15 | リン酸結合性ポリマー製剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6383518B1 (enExample) |
| EP (2) | EP1304104B1 (enExample) |
| JP (2) | JP2009173687A (enExample) |
| KR (1) | KR100456202B1 (enExample) |
| CN (1) | CN1180782C (enExample) |
| AT (2) | ATE364377T1 (enExample) |
| AU (1) | AU726142B2 (enExample) |
| CA (1) | CA2286003C (enExample) |
| CY (1) | CY1106823T1 (enExample) |
| DE (2) | DE69837945T2 (enExample) |
| DK (1) | DK1304104T3 (enExample) |
| ES (2) | ES2201463T3 (enExample) |
| PT (1) | PT1304104E (enExample) |
| TW (1) | TW592727B (enExample) |
| WO (1) | WO1998044933A1 (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9720061D0 (en) | 1997-09-19 | 1997-11-19 | Crosfield Joseph & Sons | Metal compounds as phosphate binders |
| JP3718341B2 (ja) | 1998-05-12 | 2005-11-24 | 信越化学工業株式会社 | 低置換度ヒドロキシプロピルセルロースとその製造方法 |
| TW568788B (en) | 1998-10-12 | 2004-01-01 | Chugai Pharmaceutical Co Ltd | Polymer combining with phosphoric acid and preparation containing the same |
| AU778262B2 (en) * | 1999-10-19 | 2004-11-25 | Genzyme Corporation | Direct compression polymer tablet core |
| US20020054903A1 (en) * | 1999-10-19 | 2002-05-09 | Joseph Tyler | Direct compression polymer tablet core |
| US6733780B1 (en) | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
| US6680069B1 (en) | 1999-11-09 | 2004-01-20 | Shin-Etsu Chemical Co., Ltd. | Low-substituted hydroxypropyl cellulose and process for manufacturing the same |
| JP3552160B2 (ja) | 2000-01-14 | 2004-08-11 | 信越化学工業株式会社 | 低置換度ヒドロキシプロピルセルロース粒子の形成方法 |
| WO2002066543A1 (en) | 2001-02-16 | 2002-08-29 | Genzyme Corporation | Method of drying a material having a cohesive phase |
| WO2002085379A1 (en) * | 2001-04-18 | 2002-10-31 | Geltex Pharmaceuticals, Inc. | Method for improving vascular access in patients with vascular shunts |
| BR0209020A (pt) | 2001-04-18 | 2004-08-10 | Genzyme Corp | Composição farmacêutica de polialilamina |
| ES2637020T3 (es) | 2001-04-18 | 2017-10-10 | Genzyme Corporation | Uso de polímero de amina para reducir la glucosa sérica |
| FR2827771B1 (fr) * | 2001-07-25 | 2003-10-24 | Apis Spheromont | Formulation et procede de preparation de spheroides pouvant etre fortement titres et a dispersion rapide |
| US6600011B2 (en) | 2001-10-09 | 2003-07-29 | Genzyme Corporation | Process for purification and drying of polymer hydrogels |
| TWI231760B (en) * | 2001-12-20 | 2005-05-01 | Chugai Pharmaceutical Co Ltd | Coated lozenge and manufacturing method thereof |
| US7608674B2 (en) | 2003-11-03 | 2009-10-27 | Ilypsa, Inc. | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
| US7335795B2 (en) | 2004-03-22 | 2008-02-26 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7385012B2 (en) * | 2003-11-03 | 2008-06-10 | Ilypsa, Inc. | Polyamine polymers |
| US7459502B2 (en) | 2003-11-03 | 2008-12-02 | Ilypsa, Inc. | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| US7767768B2 (en) | 2003-11-03 | 2010-08-03 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7449605B2 (en) | 2003-11-03 | 2008-11-11 | Ilypsa, Inc. | Crosslinked amine polymers |
| US20060177415A1 (en) * | 2004-11-01 | 2006-08-10 | Burke Steven K | Once a day formulation for phosphate binders |
| US7985418B2 (en) | 2004-11-01 | 2011-07-26 | Genzyme Corporation | Aliphatic amine polymer salts for tableting |
| EP1869090A1 (en) * | 2005-03-16 | 2007-12-26 | Council Of Scientific And Industrial Research | An improved process for the preparation of crosslinked polyallylamine polymer. |
| JP2009507019A (ja) * | 2005-09-02 | 2009-02-19 | ジェンザイム・コーポレーション | リン酸塩を除去する方法およびそれに使用される重合体 |
| KR101547925B1 (ko) | 2005-09-15 | 2015-08-27 | 젠자임 코포레이션 | 아민 중합체에 대한 샤셋 제형 |
| MY157620A (en) | 2006-01-31 | 2016-06-30 | Cytochroma Dev Inc | A granular material of a solid water-soluble mixed metal compound capable of binding phosphate |
| GB0601899D0 (en) * | 2006-01-31 | 2006-03-08 | Ineos Silicas Ltd | Compositions |
| EP1818048B1 (en) * | 2006-02-14 | 2009-01-07 | Teva Pharmaceutical Industries, Inc. | Pharmaceutical formulations of aliphatic amine polymers and methods for their manufacture |
| WO2007094779A1 (en) * | 2006-02-14 | 2007-08-23 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical formulations of aliphatic amine polymers and methods for their manufacture |
| JP2009536246A (ja) * | 2006-05-05 | 2009-10-08 | ゲンズイメ コーポレーション | ホスフェート捕捉剤としてのアミン縮合重合体 |
| CA2658338A1 (en) * | 2006-07-18 | 2008-01-24 | Genzyme Corporation | Amine dendrimers |
| US7964182B2 (en) | 2006-09-01 | 2011-06-21 | USV, Ltd | Pharmaceutical compositions comprising phosphate-binding polymer |
| BRPI0717008A2 (pt) * | 2006-09-01 | 2014-01-21 | Usv Ltd | Processo para o preparo de cloridrato de sevelamer e formulação do mesmo |
| WO2008042222A2 (en) | 2006-09-29 | 2008-04-10 | Genzyme Corporation | Amide dendrimer compositions |
| WO2008076242A1 (en) | 2006-12-14 | 2008-06-26 | Genzyme Corporation | Amido-amine polymer compositions |
| EP2114376A1 (en) * | 2007-02-23 | 2009-11-11 | Genzyme Corporation | Amine polymer compositions |
| WO2008109095A1 (en) * | 2007-03-08 | 2008-09-12 | Genzyme Corporation | Sulfone polymer compositions |
| US20100166696A1 (en) * | 2007-04-27 | 2010-07-01 | Dhal Pradeep K | Amido-amine dendrimer compositions |
| GB0714670D0 (en) | 2007-07-27 | 2007-09-05 | Ineos Healthcare Ltd | Use |
| WO2009034540A1 (en) * | 2007-09-11 | 2009-03-19 | Ranbaxy Laboratories Limited | Pharmaceutical composition of sevelamer |
| GB0720220D0 (en) | 2007-10-16 | 2007-11-28 | Ineos Healthcare Ltd | Compound |
| JP2011506449A (ja) * | 2007-12-14 | 2011-03-03 | ジェンザイム コーポレーション | コーティング医薬組成物 |
| WO2009154747A1 (en) * | 2008-06-20 | 2009-12-23 | Genzyme Corporation | Pharmaceutical compositions |
| DE102008030046A1 (de) | 2008-06-25 | 2009-12-31 | Ratiopharm Gmbh | Kompaktiertes Polyallylamin-Polymer |
| AU2010209293A1 (en) * | 2009-01-22 | 2011-09-08 | Usv Limited | Pharmaceutical compositions comprising phosphate-binding polymer |
| US20100330175A1 (en) * | 2009-06-24 | 2010-12-30 | Jobdevairakkam Christopher N | Cross-linked polyallylamine tablet core |
| WO2010149794A2 (en) | 2009-06-26 | 2010-12-29 | Combino Pharm, S.L. | Novel pharmaceutical composition comprising poly (allylamin-co-n,n'-diallyl- 1,3-diamino-2-hydroxypropane) |
| GB0913525D0 (en) | 2009-08-03 | 2009-09-16 | Ineos Healthcare Ltd | Method |
| DK2490675T3 (en) * | 2009-10-22 | 2019-04-29 | Synthon Bv | Pharmaceutical compositions with sevelamer |
| GB201001779D0 (en) | 2010-02-04 | 2010-03-24 | Ineos Healthcare Ltd | Composition |
| EP2545907A1 (en) | 2011-07-15 | 2013-01-16 | Combino Pharm, S.L. | Aqueous wet granulation process for cross-linked polyallylamine polymers |
| MA41202A (fr) | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
| WO2016135065A1 (en) * | 2015-02-23 | 2016-09-01 | Amneal Pharmaceuticals Company Gmbh | Process for granulating sevelamer carbonate |
| WO2018124264A1 (ja) | 2016-12-28 | 2018-07-05 | 富士フイルム株式会社 | 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法 |
| JP6992084B2 (ja) | 2017-10-16 | 2022-01-13 | 富士フイルム株式会社 | 高リン血症治療剤 |
| CA3079171C (en) * | 2017-10-16 | 2023-09-12 | Fujifilm Corporation | Therapeutic agent for hyperphosphatemia and particles |
| JP2019182818A (ja) * | 2018-04-17 | 2019-10-24 | ライオン株式会社 | 舌苔除去用の口腔内崩壊錠及び舌苔除去方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6090243A (ja) | 1983-10-25 | 1985-05-21 | Nitto Boseki Co Ltd | 小球状モノアリルアミン橋かけ重合体の製造方法 |
| US4631305A (en) | 1985-03-22 | 1986-12-23 | The Upjohn Company | Polymeric material as a disintegrant in a compressed tablet |
| DE3776116D1 (de) * | 1986-12-30 | 1992-02-27 | American Cyanamid Co | Zusammensetzung die ein polycarbophil enthaelt. |
| US4956182A (en) * | 1989-03-16 | 1990-09-11 | Bristol-Myers Company | Direct compression cholestyramine tablet and solvent-free coating therefor |
| JPH02286621A (ja) * | 1989-04-26 | 1990-11-26 | Mitsubishi Kasei Corp | 経口コレステロール低下剤 |
| JPH0413627A (ja) * | 1990-04-27 | 1992-01-17 | Mitsubishi Kasei Corp | 経口コレステロール低下剤 |
| JP2609022B2 (ja) * | 1990-11-29 | 1997-05-14 | 北陸製薬株式会社 | ポリカルボフィルカルシウム含有製剤 |
| JPH06157325A (ja) * | 1992-11-30 | 1994-06-03 | Mitsubishi Kasei Corp | 経口コレステロール低下剤 |
| TW272942B (enExample) | 1993-02-10 | 1996-03-21 | Takeda Pharm Industry Co Ltd | |
| US5667775A (en) * | 1993-08-11 | 1997-09-16 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
| US5496545A (en) * | 1993-08-11 | 1996-03-05 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
| WO1996021454A1 (en) | 1995-01-12 | 1996-07-18 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
| JP3836893B2 (ja) * | 1995-01-24 | 2006-10-25 | アボットジャパン株式会社 | ポリカルボフィルカルシウム含有製剤 |
| TW438608B (en) * | 1995-08-02 | 2001-06-07 | Hisamitsu Pharmaceutical Co | A tablet containing anion exchange resin |
| JP3389493B2 (ja) * | 1997-04-04 | 2003-03-24 | 中外製薬株式会社 | リン酸結合性ポリマー製剤 |
-
1998
- 1998-03-19 TW TW087104092A patent/TW592727B/zh not_active IP Right Cessation
- 1998-04-03 CA CA002286003A patent/CA2286003C/en not_active Expired - Lifetime
- 1998-04-03 ES ES98911187T patent/ES2201463T3/es not_active Expired - Lifetime
- 1998-04-03 DE DE69837945T patent/DE69837945T2/de not_active Expired - Lifetime
- 1998-04-03 EP EP02025683A patent/EP1304104B1/en not_active Expired - Lifetime
- 1998-04-03 AT AT02025683T patent/ATE364377T1/de active
- 1998-04-03 AT AT98911187T patent/ATE244013T1/de active
- 1998-04-03 WO PCT/JP1998/001536 patent/WO1998044933A1/ja not_active Ceased
- 1998-04-03 PT PT02025683T patent/PT1304104E/pt unknown
- 1998-04-03 CN CNB988046245A patent/CN1180782C/zh not_active Expired - Lifetime
- 1998-04-03 DE DE69816082T patent/DE69816082T2/de not_active Expired - Lifetime
- 1998-04-03 DK DK02025683T patent/DK1304104T3/da active
- 1998-04-03 ES ES02025683T patent/ES2287215T3/es not_active Expired - Lifetime
- 1998-04-03 KR KR10-1999-7009058A patent/KR100456202B1/ko not_active Expired - Lifetime
- 1998-04-03 US US09/381,506 patent/US6383518B1/en not_active Expired - Lifetime
- 1998-04-03 AU AU65223/98A patent/AU726142B2/en not_active Expired
- 1998-04-03 EP EP98911187A patent/EP0997148B1/en not_active Expired - Lifetime
-
2002
- 2002-03-06 US US10/090,622 patent/US6696087B2/en not_active Expired - Lifetime
-
2007
- 2007-08-23 CY CY20071101107T patent/CY1106823T1/el unknown
-
2009
- 2009-05-15 JP JP2009118371A patent/JP2009173687A/ja not_active Withdrawn
-
2012
- 2012-10-18 JP JP2012230662A patent/JP5681156B2/ja not_active Expired - Fee Related
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