CN1180782C - 磷酸结合性聚合物制剂 - Google Patents

磷酸结合性聚合物制剂 Download PDF

Info

Publication number
CN1180782C
CN1180782C CNB988046245A CN98804624A CN1180782C CN 1180782 C CN1180782 C CN 1180782C CN B988046245 A CNB988046245 A CN B988046245A CN 98804624 A CN98804624 A CN 98804624A CN 1180782 C CN1180782 C CN 1180782C
Authority
CN
China
Prior art keywords
tablet
phosphate
record
binding polymer
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB988046245A
Other languages
English (en)
Chinese (zh)
Other versions
CN1254287A (zh
Inventor
��ʤҲ
松田胜也
窪田隆二
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of CN1254287A publication Critical patent/CN1254287A/zh
Application granted granted Critical
Publication of CN1180782C publication Critical patent/CN1180782C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
CNB988046245A 1997-04-04 1998-04-03 磷酸结合性聚合物制剂 Expired - Lifetime CN1180782C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8658197 1997-04-04
JP86581/1997 1997-04-04

Publications (2)

Publication Number Publication Date
CN1254287A CN1254287A (zh) 2000-05-24
CN1180782C true CN1180782C (zh) 2004-12-22

Family

ID=13890981

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988046245A Expired - Lifetime CN1180782C (zh) 1997-04-04 1998-04-03 磷酸结合性聚合物制剂

Country Status (15)

Country Link
US (2) US6383518B1 (enExample)
EP (2) EP1304104B1 (enExample)
JP (2) JP2009173687A (enExample)
KR (1) KR100456202B1 (enExample)
CN (1) CN1180782C (enExample)
AT (2) ATE364377T1 (enExample)
AU (1) AU726142B2 (enExample)
CA (1) CA2286003C (enExample)
CY (1) CY1106823T1 (enExample)
DE (2) DE69837945T2 (enExample)
DK (1) DK1304104T3 (enExample)
ES (2) ES2201463T3 (enExample)
PT (1) PT1304104E (enExample)
TW (1) TW592727B (enExample)
WO (1) WO1998044933A1 (enExample)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
JP3718341B2 (ja) 1998-05-12 2005-11-24 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロースとその製造方法
TW568788B (en) 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
AU778262B2 (en) * 1999-10-19 2004-11-25 Genzyme Corporation Direct compression polymer tablet core
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US6680069B1 (en) 1999-11-09 2004-01-20 Shin-Etsu Chemical Co., Ltd. Low-substituted hydroxypropyl cellulose and process for manufacturing the same
JP3552160B2 (ja) 2000-01-14 2004-08-11 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース粒子の形成方法
WO2002066543A1 (en) 2001-02-16 2002-08-29 Genzyme Corporation Method of drying a material having a cohesive phase
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
BR0209020A (pt) 2001-04-18 2004-08-10 Genzyme Corp Composição farmacêutica de polialilamina
ES2637020T3 (es) 2001-04-18 2017-10-10 Genzyme Corporation Uso de polímero de amina para reducir la glucosa sérica
FR2827771B1 (fr) * 2001-07-25 2003-10-24 Apis Spheromont Formulation et procede de preparation de spheroides pouvant etre fortement titres et a dispersion rapide
US6600011B2 (en) 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
TWI231760B (en) * 2001-12-20 2005-05-01 Chugai Pharmaceutical Co Ltd Coated lozenge and manufacturing method thereof
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7385012B2 (en) * 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7459502B2 (en) 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7767768B2 (en) 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7449605B2 (en) 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
EP1869090A1 (en) * 2005-03-16 2007-12-26 Council Of Scientific And Industrial Research An improved process for the preparation of crosslinked polyallylamine polymer.
JP2009507019A (ja) * 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
KR101547925B1 (ko) 2005-09-15 2015-08-27 젠자임 코포레이션 아민 중합체에 대한 샤셋 제형
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
GB0601899D0 (en) * 2006-01-31 2006-03-08 Ineos Silicas Ltd Compositions
EP1818048B1 (en) * 2006-02-14 2009-01-07 Teva Pharmaceutical Industries, Inc. Pharmaceutical formulations of aliphatic amine polymers and methods for their manufacture
WO2007094779A1 (en) * 2006-02-14 2007-08-23 Teva Pharmaceutical Industries Ltd. Pharmaceutical formulations of aliphatic amine polymers and methods for their manufacture
JP2009536246A (ja) * 2006-05-05 2009-10-08 ゲンズイメ コーポレーション ホスフェート捕捉剤としてのアミン縮合重合体
CA2658338A1 (en) * 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
US7964182B2 (en) 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
BRPI0717008A2 (pt) * 2006-09-01 2014-01-21 Usv Ltd Processo para o preparo de cloridrato de sevelamer e formulação do mesmo
WO2008042222A2 (en) 2006-09-29 2008-04-10 Genzyme Corporation Amide dendrimer compositions
WO2008076242A1 (en) 2006-12-14 2008-06-26 Genzyme Corporation Amido-amine polymer compositions
EP2114376A1 (en) * 2007-02-23 2009-11-11 Genzyme Corporation Amine polymer compositions
WO2008109095A1 (en) * 2007-03-08 2008-09-12 Genzyme Corporation Sulfone polymer compositions
US20100166696A1 (en) * 2007-04-27 2010-07-01 Dhal Pradeep K Amido-amine dendrimer compositions
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
WO2009034540A1 (en) * 2007-09-11 2009-03-19 Ranbaxy Laboratories Limited Pharmaceutical composition of sevelamer
GB0720220D0 (en) 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
JP2011506449A (ja) * 2007-12-14 2011-03-03 ジェンザイム コーポレーション コーティング医薬組成物
WO2009154747A1 (en) * 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
DE102008030046A1 (de) 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
AU2010209293A1 (en) * 2009-01-22 2011-09-08 Usv Limited Pharmaceutical compositions comprising phosphate-binding polymer
US20100330175A1 (en) * 2009-06-24 2010-12-30 Jobdevairakkam Christopher N Cross-linked polyallylamine tablet core
WO2010149794A2 (en) 2009-06-26 2010-12-29 Combino Pharm, S.L. Novel pharmaceutical composition comprising poly (allylamin-co-n,n'-diallyl- 1,3-diamino-2-hydroxypropane)
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
DK2490675T3 (en) * 2009-10-22 2019-04-29 Synthon Bv Pharmaceutical compositions with sevelamer
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
EP2545907A1 (en) 2011-07-15 2013-01-16 Combino Pharm, S.L. Aqueous wet granulation process for cross-linked polyallylamine polymers
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
WO2016135065A1 (en) * 2015-02-23 2016-09-01 Amneal Pharmaceuticals Company Gmbh Process for granulating sevelamer carbonate
WO2018124264A1 (ja) 2016-12-28 2018-07-05 富士フイルム株式会社 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法
JP6992084B2 (ja) 2017-10-16 2022-01-13 富士フイルム株式会社 高リン血症治療剤
CA3079171C (en) * 2017-10-16 2023-09-12 Fujifilm Corporation Therapeutic agent for hyperphosphatemia and particles
JP2019182818A (ja) * 2018-04-17 2019-10-24 ライオン株式会社 舌苔除去用の口腔内崩壊錠及び舌苔除去方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4631305A (en) 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
DE3776116D1 (de) * 1986-12-30 1992-02-27 American Cyanamid Co Zusammensetzung die ein polycarbophil enthaelt.
US4956182A (en) * 1989-03-16 1990-09-11 Bristol-Myers Company Direct compression cholestyramine tablet and solvent-free coating therefor
JPH02286621A (ja) * 1989-04-26 1990-11-26 Mitsubishi Kasei Corp 経口コレステロール低下剤
JPH0413627A (ja) * 1990-04-27 1992-01-17 Mitsubishi Kasei Corp 経口コレステロール低下剤
JP2609022B2 (ja) * 1990-11-29 1997-05-14 北陸製薬株式会社 ポリカルボフィルカルシウム含有製剤
JPH06157325A (ja) * 1992-11-30 1994-06-03 Mitsubishi Kasei Corp 経口コレステロール低下剤
TW272942B (enExample) 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
WO1996021454A1 (en) 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
JP3836893B2 (ja) * 1995-01-24 2006-10-25 アボットジャパン株式会社 ポリカルボフィルカルシウム含有製剤
TW438608B (en) * 1995-08-02 2001-06-07 Hisamitsu Pharmaceutical Co A tablet containing anion exchange resin
JP3389493B2 (ja) * 1997-04-04 2003-03-24 中外製薬株式会社 リン酸結合性ポリマー製剤

Also Published As

Publication number Publication date
ES2287215T3 (es) 2007-12-16
JP2009173687A (ja) 2009-08-06
DK1304104T3 (da) 2007-07-16
EP1304104A2 (en) 2003-04-23
DE69837945D1 (de) 2007-07-26
TW592727B (en) 2004-06-21
DE69837945T2 (de) 2008-02-21
US20020122786A1 (en) 2002-09-05
DE69816082D1 (de) 2003-08-07
PT1304104E (pt) 2007-07-27
CA2286003A1 (en) 1998-10-15
ATE364377T1 (de) 2007-07-15
CY1106823T1 (el) 2012-05-23
ATE244013T1 (de) 2003-07-15
JP5681156B2 (ja) 2015-03-04
EP0997148B1 (en) 2003-07-02
EP0997148A4 (en) 2000-05-03
CN1254287A (zh) 2000-05-24
AU6522398A (en) 1998-10-30
JP2013010803A (ja) 2013-01-17
EP1304104A3 (en) 2003-11-12
EP0997148A1 (en) 2000-05-03
EP1304104B1 (en) 2007-06-13
HK1055387A1 (en) 2004-01-09
CA2286003C (en) 2007-06-05
US6696087B2 (en) 2004-02-24
AU726142B2 (en) 2000-11-02
KR20010005980A (ko) 2001-01-15
HK1027506A1 (en) 2001-01-19
KR100456202B1 (ko) 2004-11-09
DE69816082T2 (de) 2004-04-15
US6383518B1 (en) 2002-05-07
WO1998044933A1 (en) 1998-10-15
ES2201463T3 (es) 2004-03-16

Similar Documents

Publication Publication Date Title
CN1180782C (zh) 磷酸结合性聚合物制剂
CN1147509C (zh) 磷酸结合性聚合物以及其制剂
JPWO2000022008A1 (ja) リン酸結合性ポリマー及びそれを使用した製剤
CN111840239B (zh) 一种普瑞巴林缓释制剂
Pradhan et al. Formulation of once a day controlled release tablet of indomethacin based on HPMC-mannitol
JP4562797B1 (ja) 沈降炭酸カルシウムを有効成分とする口腔内崩壊錠
WO2007025182A2 (en) Drug compositions containing controlled release hypromellose matrices
RU2367438C2 (ru) Матриксная таблетка с регулируемым высвобождением триметазидина
CN1241568C (zh) 复方氨酚那敏缓释片和制备方法
CN103191432A (zh) 一种水溶性药物骨架缓释片及其制备方法
JP2002234912A (ja) リン酸結合性ポリマー及びそれを使用した製剤
KR102897443B1 (ko) 제어 방출형 미라베그론 제제 및 이의 제조방법
Sørensen Formulation and evaluation of sustained-release matrix tablets of metformin hydrochloride using natural polymers
CN1739575A (zh) 用于消化道疾病的凹凸棒石固体及液体制剂
CN1795846A (zh) 盐酸二甲双胍口服固体制剂及其制备方法
CN115590831A (zh) 一种富马酸二甲酯缓释微片及其制备方法
JP2003183168A (ja) リン酸結合性ポリマー含有製剤
WO2020249500A1 (en) Stable tablet formulation of nifurtimox and process for producing the same
KR20210001710A (ko) 제어 방출형 미라베그론 제제 및 이의 제조방법
CN1557306A (zh) 苦参素分散片
US20130303632A1 (en) Controlled release solid dose form
JP2002265371A (ja) リン酸結合性ポリマー製剤
HK1055387B (en) Tablet comprising a phosphate-binding polymer
CN1634012A (zh) 阿魏酸钠胶囊及其制备方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20041222