MA41202A - Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 - Google Patents

Copolymères polydiallymine réticulé pour le traitement du diabète de type 2

Info

Publication number
MA41202A
MA41202A MA041202A MA41202A MA41202A MA 41202 A MA41202 A MA 41202A MA 041202 A MA041202 A MA 041202A MA 41202 A MA41202 A MA 41202A MA 41202 A MA41202 A MA 41202A
Authority
MA
Morocco
Prior art keywords
polydiallymine
diabetes
copolymers
linked
treatment
Prior art date
Application number
MA041202A
Other languages
English (en)
Inventor
Chinyere Agbugba
Ian Davison
Pradeep K Dhal
Thomas Huebschle
Philip Just Larsen
Peter Mcdonnell
Robert J Miller
Steven C Polomoscanik
Thorsten Schmidt
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of MA41202A publication Critical patent/MA41202A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F299/00—Macromolecular compounds obtained by interreacting polymers involving only carbon-to-carbon unsaturated bond reactions, in the absence of non-macromolecular monomers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C08F226/04—Diallylamine
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/08—Epoxidation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0025—Crosslinking or vulcanising agents; including accelerators
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/15—Heterocyclic compounds having oxygen in the ring
    • C08K5/151—Heterocyclic compounds having oxygen in the ring having one oxygen atom in the ring
    • C08K5/1515—Three-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F26/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F26/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C08F26/04—Diallylamine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Resins (AREA)
MA041202A 2014-12-18 2015-12-15 Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 MA41202A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462093751P 2014-12-18 2014-12-18

Publications (1)

Publication Number Publication Date
MA41202A true MA41202A (fr) 2017-10-24

Family

ID=55221501

Family Applications (2)

Application Number Title Priority Date Filing Date
MA041202A MA41202A (fr) 2014-12-18 2015-12-15 Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
MA40697A MA40697A1 (fr) 2014-12-18 2015-12-16 Copolymères polydiallymine réticulé pour le traitement du diabète de type 2

Family Applications After (1)

Application Number Title Priority Date Filing Date
MA40697A MA40697A1 (fr) 2014-12-18 2015-12-16 Copolymères polydiallymine réticulé pour le traitement du diabète de type 2

Country Status (27)

Country Link
US (1) US11267924B2 (fr)
EP (1) EP3233090A2 (fr)
JP (2) JP6866293B2 (fr)
KR (1) KR20170096008A (fr)
CN (1) CN107250189A (fr)
AR (1) AR103175A1 (fr)
AU (1) AU2015362590A1 (fr)
BR (1) BR112017012794A2 (fr)
CA (1) CA2971204A1 (fr)
CL (1) CL2017001579A1 (fr)
CO (1) CO2017007119A2 (fr)
CR (1) CR20170323A (fr)
DO (1) DOP2017000140A (fr)
EA (1) EA201791380A1 (fr)
EC (1) ECSP17045972A (fr)
GT (1) GT201700133A (fr)
HK (1) HK1251449A1 (fr)
IL (1) IL252899A0 (fr)
MA (2) MA41202A (fr)
MX (1) MX2017007966A (fr)
PE (1) PE20171510A1 (fr)
PH (1) PH12017501120A1 (fr)
SG (1) SG11201704840RA (fr)
TN (1) TN2017000253A1 (fr)
TW (1) TW201636030A (fr)
UY (1) UY36457A (fr)
WO (1) WO2016100456A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI784968B (zh) 2016-09-09 2022-12-01 丹麥商西蘭製藥公司 澱粉素類似物
US10479865B2 (en) * 2017-11-01 2019-11-19 Strides Shasun Limited Process for the preparation of sevelamer carbonate
US12295369B2 (en) 2019-08-07 2025-05-13 Solventum Intellectual Properties Company Articles containing a crosslinked guanidinyl-containing polymer and uses thereof
EP4031553A4 (fr) * 2019-09-20 2023-11-01 Glyscend, Inc. Polymères contenant de l'acide phénylboronique substitué et procédés d'utilisation
JP2024512296A (ja) * 2021-03-01 2024-03-19 トリシダ・インコーポレイテッド 架橋ポリ（アリルアミン）ポリマー医薬組成物

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2456428A (en) 1944-10-11 1948-12-14 Shell Dev Polyallyl amine and related polymeric amines
BE580490A (fr) 1958-07-15 1960-01-08 Merck & Co Inc Compositions et procédés pour abaisser la teneur en cholestérol du sang
US3104205A (en) 1959-12-17 1963-09-17 Warner Lambert Pharmaceutical Deodorant composition comprising the copper complex of the copolymer of allylamine and methacrylic acid
US3308020A (en) 1961-09-22 1967-03-07 Merck & Co Inc Compositions and method for binding bile acids in vivo including hypocholesteremics
US3332841A (en) 1961-10-04 1967-07-25 Lilly Co Eli Method of treating hyperacidity
BE640616A (fr) 1962-12-19
US3293195A (en) 1963-11-29 1966-12-20 Ritter Pfaudler Corp Ion exchange resins prepared from a mixed resin of vinyl pyridine copolymers and epihalohydrins-polyalkylene polyamines and methods of making and using same
US3624209A (en) 1966-12-28 1971-11-30 Bristol Myers Co Composition for treatment of gastro-intestinal disorders
US3492397A (en) 1967-04-07 1970-01-27 Warner Lambert Pharmaceutical Sustained release dosage in the pellet form and process thereof
US4060598A (en) 1967-06-28 1977-11-29 Boehringer Mannheim G.M.B.H. Tablets coated with aqueous resin dispersions
DE1927336A1 (de) 1968-06-17 1969-12-18 Upjohn Co Orale Dosierungsform zur Bekaempfung von Hypercholesterinaemie
US3538214A (en) 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
US3980770A (en) 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
CH604722A5 (fr) 1973-02-09 1978-09-15 Sandoz Ag
US4205064A (en) 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
AR206115A1 (es) 1973-06-11 1976-06-30 Merck & Co Inc Procedimiento para preparar un polimero lineal no ramificado y no reticulado
US4016209A (en) 1975-04-23 1977-04-05 Merck & Co., Inc. 3-[N'-(3-Halopropyl)-N-'-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof
US4181718A (en) 1975-12-29 1980-01-01 Mason Norbert S Polyanion-stabilized aluminum hydrogels
US4071478A (en) 1976-06-07 1978-01-31 Merck & Co., Inc. Controlled partially cross-linked 3,3-ionenes
US4183918A (en) 1977-03-08 1980-01-15 Exxon Research & Engineering Co. Detoxifying-medicinal emulsions
GB1573487A (en) 1977-05-23 1980-08-28 Bristol Myers Co Bile acid binding composition
US4143130A (en) 1977-08-29 1979-03-06 Warren-Teed Laboratories, Inc. Method for treating kidney stones
US4368725A (en) 1977-11-11 1983-01-18 Mcclintock Michael Solar energy collector
US4173626A (en) 1978-12-11 1979-11-06 Merck & Co., Inc. Sustained release indomethacin
US4247393A (en) 1979-01-11 1981-01-27 Wallace Richard A Hemodialysis assist device
US4439419A (en) 1980-02-20 1984-03-27 The Upjohn Company Method of treating gastric hyperacidity in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance as epichlorhydrin
US4344993A (en) 1980-09-02 1982-08-17 The Dow Chemical Company Perfluorocarbon-polymeric coatings having low critical surface tensions
IE52006B1 (en) 1980-12-12 1987-05-13 Smith & Nephew Ass Polymers of diallyl ammonium monomers pharmaceutical compositions thereof
US4504640A (en) 1982-05-19 1985-03-12 Nitto Boseki Co., Ltd. Process for producing monoallylamine polymer
JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
DE3572985D1 (en) 1984-05-11 1989-10-19 Bristol Myers Co Novel bile sequestrant resin and uses
US4631305A (en) 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
DE3541511A1 (de) 1985-11-19 1987-05-21 Grace W R Ab Promoter fuer die papierleimung, verfahren zu dessen herstellung und dessen verwendung
AU628389B2 (en) 1988-08-26 1992-09-17 Pharmacia & Upjohn Company Fine-beaded colestipol hydrochloride
GB8829835D0 (en) 1988-12-21 1989-02-15 Smith Kline French Lab Compounds
DE3901527A1 (de) 1989-01-20 1990-07-26 Hoechst Ag Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate
US6274713B1 (en) 1989-04-07 2001-08-14 Salutar, Inc. Polychelants
US5236701A (en) 1989-07-19 1993-08-17 Lowchol Scientific Inc. Ingestible hydrophilic polymeric amines useful for lowering blood cholesterol
US5136032A (en) 1989-12-07 1992-08-04 Daicel Chemical Industries, Ltd. Method for separating phosphopolyol compounds using a separating agent
US5053423A (en) 1990-03-22 1991-10-01 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
JPH0687974B2 (ja) 1990-03-27 1994-11-09 忠一 平山 発熱物質の吸着材料
DE4010271A1 (de) 1990-03-30 1991-10-02 Basf Ag Verfahren zur herstellung von ethylenpolymerisaten bei druecken oberhalb von 500 bar in einem rohrreaktor mit einspritzfinger
IE914179A1 (en) 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
RU1808015C (ru) 1990-12-27 1993-04-07 Владимир Андреевич Шевченко Способ защиты млекопитающих от воздействи гамма-излучени
US5055197A (en) 1991-04-05 1991-10-08 Rohm And Haas Company Process for removing residual monomers and oligemers from amine-containing polymers
US5108767A (en) 1991-06-10 1992-04-28 Abbott Laboratories Liquid nutritional product for persons receiving renal dialysis
SK281920B6 (sk) 1991-07-03 2001-09-11 Pharmacia And Upjohn Company Farmaceutická tableta na báze ionexových živíc a spôsob jej výroby
EP0534304A1 (fr) 1991-09-21 1993-03-31 Hoechst Aktiengesellschaft Polyéthelèneimines à substitution cycloalcoylée et leurs utilisations comme agents hypolipémiants
SE470006B (sv) 1991-09-26 1993-10-25 Corline Systems Ab Nytt konjugat, dess framställning och användning samt substrat preparerat med konjugatet
ATE159262T1 (de) 1992-07-22 1997-11-15 Hoechst Ag Hydrophile zentren aufweisende polyvinylamin- derivate, verfahren zu ihrer herstellung sowie die verwendung der verbindungen als arzneimittel, wirkstoffträger und nahrungsmittelhilfsstoff
DE59304725D1 (de) 1992-07-22 1997-01-23 Hoechst Ag Vernetzte, stickstoffhaltige Vinylcopolymere, Verfahren zu ihrer Herstellung sowie die Verwendung dieser Verbindungen
DE69319914T2 (de) 1992-08-20 1999-01-21 E.I. Du Pont De Nemours And Co., Wilmington, Del. Vernetzte polymerische ammoniumsalze
US5302531A (en) 1992-10-22 1994-04-12 Miles Inc. Composition for the semiquantitative determination of specific gravity of a test sample
DE69330595T2 (de) 1992-11-25 2002-05-23 Ajinomoto Co., Inc. Zubereitungen und Nahrungsmittel enthaltend Mineralien und Poly-gamma-Glutaminsäure
GB2276170B (en) 1993-02-17 1997-04-16 British Tech Group Polymers containing guanidine groups for use in therapy
US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
JPH09500368A (ja) 1993-06-02 1997-01-14 ジェルテックス ファーマシューティカルズ，インコーポレイテッド 胆汁酸塩を除去するための組成物および方法
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
JPH0788181A (ja) * 1993-09-21 1995-04-04 Mitsubishi Rayon Co Ltd エンドトキシン吸着材及び製法
US5414068A (en) 1994-01-24 1995-05-09 Rohm And Haas Company Crosslinked anion exchange particles and method for producing the particles
WO1996021454A1 (fr) 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Polymeres fixant les phosphates destines a etre administres par voie orale
GB9503061D0 (en) 1995-02-16 1995-04-05 British Tech Group Polymeric compounds
JP2936129B2 (ja) 1995-04-12 1999-08-23 セイコー精機株式会社 防食構造
FI104823B (fi) 1996-06-24 2000-04-14 Borealis Polymers Oy Likaantumista estävä päällyste
JP3389493B2 (ja) 1997-04-04 2003-03-24 中外製薬株式会社 リン酸結合性ポリマー製剤
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
US6083497A (en) * 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US5985938A (en) 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6566407B2 (en) 1997-11-05 2003-05-20 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
DE19835467A1 (de) 1998-08-06 2000-02-17 Elenac Gmbh Feststoffreaktor mit antistatischer Beschichtung zur Durchführung von Reaktionen in der Gasphase
TW568788B (en) 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US6500527B2 (en) 2001-02-01 2002-12-31 3M Innovative Properties Company Image receptor sheet
NZ528831A (en) * 2001-04-18 2005-07-29 Genzyme Corp Method for lowering serum glucose
ITMI20021718A1 (it) 2002-07-31 2004-02-01 Sematic Italia Spa Interruttore di sicurezza con sistema elettronico programmabile.
EP1699442A2 (fr) 2003-12-31 2006-09-13 Genzyme Corporation Agents sequestrants des acides biliaires a base de polymeres d'amine aliphatique a revetement gastro-resistant
EP1559419A1 (fr) * 2004-01-23 2005-08-03 Fournier Laboratories Ireland Limited Composition pharmaceutique contenant une combinaison de mefformine et d'un fibrate et les procédés pour les obtenir
US20060024368A1 (en) 2004-07-30 2006-02-02 Reza Fassihi Compressed composite delivery system for release-rate modulation of bioactives
WO2006041150A1 (fr) * 2004-10-15 2006-04-20 Mitsubishi Pharma Corporation Agent prophylactique et/ou thérapeutique pour le traitement de diabètes
US20060177415A1 (en) 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
EP2016947A1 (fr) * 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Nouveau processus à une étape pour préparer des polymères poly(allylamine) réticulés
PA8807201A1 (es) * 2007-12-14 2009-07-23 Genzyme Corp Composiciones farmaceuticas
CA2790999C (fr) 2010-02-24 2019-05-14 Relypsa, Inc. Polyvinylamine, polyallylamine et polyethyleneimine reticulees pour l'utilisation comme sequestrants de l'acide biliaire
ES2661079T3 (es) * 2010-02-24 2018-03-27 Relypsa, Inc. Polímeros de amina para su uso como secuestrantes de ácidos biliares
CN106478948B (zh) 2010-02-24 2019-05-07 瑞立普萨公司 用作胆汁酸螯合剂的聚咪唑
US20130156720A1 (en) * 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
EP2968403A1 (fr) * 2013-03-15 2016-01-20 Genzyme Corporation Agents séquestrants de précurseurs de produits terminaux de glycation avancée (age)

Also Published As

Publication number Publication date
AU2015362590A1 (en) 2017-08-03
JP6866293B2 (ja) 2021-05-12
CA2971204A1 (fr) 2016-06-23
WO2016100456A2 (fr) 2016-06-23
CO2017007119A2 (es) 2017-08-18
CR20170323A (es) 2017-08-22
TN2017000253A1 (en) 2018-10-19
TW201636030A (zh) 2016-10-16
MX2017007966A (es) 2018-03-15
BR112017012794A2 (pt) 2018-01-02
CL2017001579A1 (es) 2018-03-23
GT201700133A (es) 2019-09-17
MA40697A1 (fr) 2018-01-31
EP3233090A2 (fr) 2017-10-25
HK1251449A1 (zh) 2019-02-01
US11267924B2 (en) 2022-03-08
PH12017501120A1 (en) 2018-01-08
CN107250189A (zh) 2017-10-13
JP2021063229A (ja) 2021-04-22
US20160177019A1 (en) 2016-06-23
KR20170096008A (ko) 2017-08-23
UY36457A (es) 2016-07-29
EA201791380A1 (ru) 2018-03-30
PE20171510A1 (es) 2017-10-20
WO2016100456A3 (fr) 2016-08-18
AR103175A1 (es) 2017-04-19
DOP2017000140A (es) 2017-07-31
SG11201704840RA (en) 2017-07-28
JP2018501358A (ja) 2018-01-18
ECSP17045972A (es) 2017-11-30
IL252899A0 (en) 2017-08-31

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