MA41449A - Polythérapies pour le traitement de cancers - Google Patents

Polythérapies pour le traitement de cancers

Info

Publication number
MA41449A
MA41449A MA041449A MA41449A MA41449A MA 41449 A MA41449 A MA 41449A MA 041449 A MA041449 A MA 041449A MA 41449 A MA41449 A MA 41449A MA 41449 A MA41449 A MA 41449A
Authority
MA
Morocco
Prior art keywords
polytherapies
cancers
treatment
Prior art date
Application number
MA041449A
Other languages
English (en)
Inventor
Paolo Julie A Di
Randall Mark Jones
Daniel B Tumas
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55398445&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA41449(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of MA41449A publication Critical patent/MA41449A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA041449A 2015-02-03 2016-01-28 Polythérapies pour le traitement de cancers MA41449A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562111604P 2015-02-03 2015-02-03

Publications (1)

Publication Number Publication Date
MA41449A true MA41449A (fr) 2017-12-12

Family

ID=55398445

Family Applications (1)

Application Number Title Priority Date Filing Date
MA041449A MA41449A (fr) 2015-02-03 2016-01-28 Polythérapies pour le traitement de cancers

Country Status (25)

Country Link
US (2) US20160220573A1 (fr)
EP (1) EP3253385A1 (fr)
JP (1) JP2018503653A (fr)
KR (1) KR20170104616A (fr)
CN (1) CN107205992A (fr)
AU (1) AU2016215643A1 (fr)
BR (1) BR112017016019A2 (fr)
CA (1) CA2974828A1 (fr)
CL (1) CL2017001943A1 (fr)
CO (1) CO2017007662A2 (fr)
CR (1) CR20170352A (fr)
CU (1) CU20170099A7 (fr)
EA (1) EA201791516A1 (fr)
EC (1) ECSP17048849A (fr)
GT (1) GT201700167A (fr)
IL (1) IL253573A0 (fr)
MA (1) MA41449A (fr)
MD (1) MD20170073A2 (fr)
MX (1) MX2017009724A (fr)
PE (1) PE20171241A1 (fr)
PH (1) PH12017550063A1 (fr)
SG (1) SG11201706107SA (fr)
SV (1) SV2017005489A (fr)
TW (1) TW201639573A (fr)
WO (1) WO2016126552A1 (fr)

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WO2010068258A1 (fr) 2008-12-08 2010-06-17 Cgi Pharmaceuticals, Inc. Inhibiteurs d'imidazopyrazine syk
KR101717809B1 (ko) 2010-03-11 2017-03-17 질레드 코네티컷 인코포레이티드 이미다조피리딘 ｓｙｋ 억제제
EP3027618B1 (fr) 2013-07-30 2020-07-08 Gilead Connecticut, Inc. Polymorphes d'inhibiteurs de syk
ES2656192T3 (es) 2013-07-31 2018-02-26 Gilead Sciences, Inc. Inhibidores de SKY
AU2014360537B2 (en) 2013-12-04 2017-09-07 Gilead Sciences, Inc. Methods for treating cancers
TWI735853B (zh) 2013-12-23 2021-08-11 美商克洛諾斯生技有限公司 脾酪胺酸激酶抑制劑
JP6310144B2 (ja) 2014-07-14 2018-04-18 ギリアード サイエンシーズ， インコーポレイテッド がんを処置するための組み合わせ
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
US10759798B2 (en) * 2016-09-14 2020-09-01 Hangzhou Solipharma Co., Ltd. ABT-199 addition salt and crystal form thereof, preparation method thereof, and pharmaceutical composition thereof
WO2018053190A1 (fr) 2016-09-14 2018-03-22 Gilead Sciences, Inc. Inhibiteurs de syk
US11364235B2 (en) * 2017-04-28 2022-06-21 Actinium Pharmaceuticals, Inc. Method for treating cancer using a BCL-2 inhibitor in conjunction with an alpha-emitting radioimmunotherapeutic
CN115028640A (zh) 2017-08-25 2022-09-09 吉利德科学公司 Syk抑制剂的多晶型物
BR112020014160A2 (pt) 2018-01-10 2020-12-08 Recurium Ip Holdings, Llc Compostos de benzamida
CN113950479A (zh) 2019-02-22 2022-01-18 克洛诺斯生物股份有限公司 作为syk抑制剂的缩合吡嗪的固体形式
JP2022537700A (ja) 2019-06-12 2022-08-29 ジュノー セラピューティクス インコーポレイテッド 細胞媒介細胞傷害性療法と生存促進性ｂｃｌ２ファミリータンパク質の阻害剤との併用療法
TWI777321B (zh) 2019-12-04 2022-09-11 大陸商蘇州亞盛藥業有限公司 藥物組合及其用途
WO2022133030A1 (fr) 2020-12-16 2022-06-23 Juno Therapeutics, Inc. Polythérapie de thérapie cellulaire et d'inhibiteur de bcl2
WO2022215995A1 (fr) * 2021-04-05 2022-10-13 주식회사 피노바이오 Polythérapie à basede 4'-thio-5-aza-2'-désoxycytidine et de vénétoclax
US20250381181A1 (en) * 2022-02-02 2025-12-18 Ono Pharmaceutical Co., Ltd. Cancer treatment agent including malt1 inhibiting drug as active ingredient
WO2023220655A1 (fr) 2022-05-11 2023-11-16 Celgene Corporation Méthodes pour surmonter la résistance aux médicaments par ré-sensibilisation de cellules cancéreuses à un traitement avec une thérapie antérieure par l'intermédiaire d'un traitement avec une thérapie par lymphocytes t

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US5059714A (en) 1988-02-25 1991-10-22 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
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US5120764A (en) 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US4997854A (en) 1989-08-25 1991-03-05 Trustees Of Boston University Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates
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EP2543389A3 (fr) 2007-08-02 2013-04-24 Gilead Biologics, Inc. Procédés et compositions de traitement et de diagnostic de fibrose, d'invasion tumorale, d'angiogenèse et de métastase
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EP3027618B1 (fr) 2013-07-30 2020-07-08 Gilead Connecticut, Inc. Polymorphes d'inhibiteurs de syk

Also Published As

Publication number Publication date
WO2016126552A1 (fr) 2016-08-11
KR20170104616A (ko) 2017-09-15
MX2017009724A (es) 2017-11-17
CA2974828A1 (fr) 2016-08-11
CR20170352A (es) 2017-09-29
AU2016215643A1 (en) 2017-08-10
CU20170099A7 (es) 2018-03-13
IL253573A0 (en) 2017-09-28
CN107205992A (zh) 2017-09-26
SG11201706107SA (en) 2017-08-30
PH12017550063A1 (en) 2018-02-05
GT201700167A (es) 2017-11-02
JP2018503653A (ja) 2018-02-08
CL2017001943A1 (es) 2018-03-02
PE20171241A1 (es) 2017-08-24
US20180117052A1 (en) 2018-05-03
ECSP17048849A (es) 2017-10-31
CO2017007662A2 (es) 2017-10-20
EA201791516A1 (ru) 2018-01-31
US20160220573A1 (en) 2016-08-04
MD20170073A2 (ro) 2018-02-28
SV2017005489A (es) 2017-10-17
EP3253385A1 (fr) 2017-12-13
TW201639573A (zh) 2016-11-16
BR112017016019A2 (pt) 2018-03-20

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