JP2012510458A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012510458A5 JP2012510458A5 JP2011538052A JP2011538052A JP2012510458A5 JP 2012510458 A5 JP2012510458 A5 JP 2012510458A5 JP 2011538052 A JP2011538052 A JP 2011538052A JP 2011538052 A JP2011538052 A JP 2011538052A JP 2012510458 A5 JP2012510458 A5 JP 2012510458A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- conr
- cor
- alkyl
- spp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 17
- 125000005843 halogen group Chemical group 0.000 claims 8
- 230000000844 anti-bacterial effect Effects 0.000 claims 6
- 230000003385 bacteriostatic effect Effects 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000001072 heteroaryl group Chemical group 0.000 claims 5
- 125000001424 substituent group Chemical group 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 229910052799 carbon Inorganic materials 0.000 claims 3
- 125000004122 cyclic group Chemical group 0.000 claims 3
- 230000000968 intestinal effect Effects 0.000 claims 3
- 241000193163 Clostridioides difficile Species 0.000 claims 2
- 150000001204 N-oxides Chemical class 0.000 claims 2
- 125000004452 carbocyclyl group Chemical group 0.000 claims 2
- 239000002207 metabolite Substances 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 229940002612 prodrug Drugs 0.000 claims 2
- 239000000651 prodrug Substances 0.000 claims 2
- 125000004076 pyridyl group Chemical group 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000012453 solvate Substances 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- UHQFBTAJFNVZIV-UHFFFAOYSA-N 2-pyridin-4-yl-6-(2-pyridin-4-yl-3h-benzimidazol-5-yl)-1h-benzimidazole Chemical compound C1=NC=CC(C=2NC3=CC=C(C=C3N=2)C=2C=C3N=C(NC3=CC=2)C=2C=CN=CC=2)=C1 UHQFBTAJFNVZIV-UHFFFAOYSA-N 0.000 claims 1
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 241000423333 Bacteroides fragilis NCTC 9343 Species 0.000 claims 1
- 241001148536 Bacteroides sp. Species 0.000 claims 1
- 241000186000 Bifidobacterium Species 0.000 claims 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 1
- 241000588722 Escherichia Species 0.000 claims 1
- 241001360526 Escherichia coli ATCC 25922 Species 0.000 claims 1
- 241000186394 Eubacterium Species 0.000 claims 1
- 241000605909 Fusobacterium Species 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 241000186660 Lactobacillus Species 0.000 claims 1
- 241000206591 Peptococcus Species 0.000 claims 1
- 241000191992 Peptostreptococcus Species 0.000 claims 1
- 241000192031 Ruminococcus Species 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229940039696 lactobacillus Drugs 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 125000003107 substituted aryl group Chemical group 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0821913.1 | 2008-12-02 | ||
| GBGB0821913.1A GB0821913D0 (en) | 2008-12-02 | 2008-12-02 | Antibacterial compounds |
| PCT/GB2009/002792 WO2010063996A2 (en) | 2008-12-02 | 2009-12-01 | Antibacterial compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014249071A Division JP2015078220A (ja) | 2008-12-02 | 2014-12-09 | 抗細菌化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012510458A JP2012510458A (ja) | 2012-05-10 |
| JP2012510458A5 true JP2012510458A5 (enExample) | 2013-01-24 |
| JP5665756B2 JP5665756B2 (ja) | 2015-02-04 |
Family
ID=40262471
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011538052A Active JP5665756B2 (ja) | 2008-12-02 | 2009-12-01 | 抗細菌化合物 |
| JP2014249071A Pending JP2015078220A (ja) | 2008-12-02 | 2014-12-09 | 抗細菌化合物 |
| JP2016212160A Pending JP2017048217A (ja) | 2008-12-02 | 2016-10-28 | 抗細菌化合物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014249071A Pending JP2015078220A (ja) | 2008-12-02 | 2014-12-09 | 抗細菌化合物 |
| JP2016212160A Pending JP2017048217A (ja) | 2008-12-02 | 2016-10-28 | 抗細菌化合物 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US8975416B2 (enExample) |
| EP (3) | EP3095783A1 (enExample) |
| JP (3) | JP5665756B2 (enExample) |
| KR (1) | KR101643435B1 (enExample) |
| CN (1) | CN102227411B (enExample) |
| AU (1) | AU2009323854B2 (enExample) |
| BR (2) | BRPI0922220B8 (enExample) |
| CA (1) | CA2744962C (enExample) |
| CY (2) | CY1116383T1 (enExample) |
| DK (2) | DK2373631T3 (enExample) |
| ES (2) | ES2537059T3 (enExample) |
| GB (1) | GB0821913D0 (enExample) |
| HR (2) | HRP20150518T1 (enExample) |
| HU (1) | HUE029151T2 (enExample) |
| IL (1) | IL213325A (enExample) |
| LT (1) | LT2907813T (enExample) |
| MX (1) | MX2011005837A (enExample) |
| NZ (1) | NZ593111A (enExample) |
| PL (2) | PL2907813T3 (enExample) |
| PT (2) | PT2373631E (enExample) |
| RS (1) | RS54904B1 (enExample) |
| RU (1) | RU2525915C2 (enExample) |
| SG (1) | SG171939A1 (enExample) |
| SI (2) | SI2907813T1 (enExample) |
| SM (2) | SMT201500117B (enExample) |
| WO (1) | WO2010063996A2 (enExample) |
| ZA (1) | ZA201103751B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0821913D0 (en) * | 2008-12-02 | 2009-01-07 | Price & Co | Antibacterial compounds |
| WO2011151620A1 (en) * | 2010-06-01 | 2011-12-08 | Summit Corporation Plc | Compounds for the treatment of clostridium difficile associated disease |
| WO2011151619A1 (en) * | 2010-06-01 | 2011-12-08 | Summit Corporation Plc | Compounds for the treatment of clostridium difficile associated disease |
| GB2480816A (en) * | 2010-06-01 | 2011-12-07 | Summit Corp Plc | Compounds for the treatment of Clostridium difficile associated diseases |
| GB2480813A (en) * | 2010-06-01 | 2011-12-07 | Summit Corp Plc | Compounds for the treatment of clostridium difficile-associated disease |
| GB2480814A (en) * | 2010-06-01 | 2011-12-07 | Summit Corp Plc | Compounds for the treatment of clostridium difficile-associated disease |
| HRP20160397T1 (hr) * | 2010-06-01 | 2016-08-12 | Summit Therapeutics Plc | Spojevi za liječenje clostridium difficile povezanih bolesti |
| US9079935B2 (en) | 2012-08-13 | 2015-07-14 | The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las Vegas | Reducing risk of contracting Clostridium-difficile associated disease |
| US8906668B2 (en) | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| NZ709392A (en) | 2012-11-23 | 2016-10-28 | Seres Therapeutics Inc | Synergistic bacterial compositions and methods of production and use thereof |
| US11185562B2 (en) | 2013-02-04 | 2021-11-30 | Seres Therapeutics, Inc. | Compositions and methods for inhibition of pathogenic bacterial growth |
| EP3904502A3 (en) | 2013-02-04 | 2022-02-23 | Seres Therapeutics, Inc. | Compositions and methods |
| HK1220326A1 (zh) | 2013-03-15 | 2017-05-05 | Seres Therapeutics, Inc. | 基於网络微生物组成和方法 |
| MX367109B (es) | 2013-11-25 | 2019-08-05 | Seres Therapeutics Inc | Composiciones bacterianas sinergicas y sus metodos de produccion y usos. |
| WO2015095241A2 (en) | 2013-12-16 | 2015-06-25 | Seres Health, Inc. | Bacterial compositions and methods of use thereof for treatment of immune system disorders |
| JP6526956B2 (ja) * | 2013-12-19 | 2019-06-05 | 花王株式会社 | 固形状組成物 |
| US9717711B2 (en) | 2014-06-16 | 2017-08-01 | The Lauridsen Group | Methods and compositions for treating Clostridium difficile associated disease |
| WO2016127102A2 (en) | 2015-02-06 | 2016-08-11 | Ernesto Abel-Santos | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis |
| AU2018318132B2 (en) | 2017-08-14 | 2025-06-26 | Seres Therapeutics, Inc. | Compositions and methods for treating cholestatic disease |
| CN111315736B (zh) * | 2017-10-05 | 2023-07-07 | 桑多斯股份公司 | 使用酸加成盐制备雷地尼唑的方法 |
| EP3703720A1 (en) | 2017-10-30 | 2020-09-09 | Seres Therapeutics, Inc. | Compositions and methods for treating antibiotic resistance |
| MX2022000598A (es) | 2019-07-17 | 2022-03-04 | Summit Oxford Ltd | Preparacion de compuestos antibacterianos. |
| MX2022006865A (es) | 2019-12-06 | 2022-07-11 | Vertex Pharma | Tetrahidrofuranos sustituidos como moduladores de canales de sodio. |
| US20210324009A1 (en) * | 2020-04-17 | 2021-10-21 | The University Of Hong Kong | Anti-bacterial calcium-dependent antibiotic (cda) analogs and methods of treating bacterial infections |
| GB202100471D0 (en) | 2021-01-14 | 2021-03-03 | Summit Oxford Ltd | Preparation of antibacterial compounds |
| GB202100470D0 (en) | 2021-01-14 | 2021-03-03 | Summit Oxford Ltd | Solid tablet dosage for of ridinilazole |
| KR20240011728A (ko) * | 2021-05-24 | 2024-01-26 | 에임맥스 테라퓨틱스, 인코포레이티드 | 세균 감염의 치료 또는 예방을 위한 프리스티나마이신 ia 및 플로프리스틴 조합 |
| CN117794920A (zh) | 2021-06-04 | 2024-03-29 | 沃泰克斯药物股份有限公司 | N-(羟烷基(杂)芳基)四氢呋喃甲酰胺作为钠通道调节剂 |
| CR20230576A (es) | 2021-06-14 | 2024-04-05 | Scorpion Therapeutics Inc | Derivados de la urea que pueden ser utilizados para tratar el cáncer |
| US12220421B2 (en) | 2021-09-09 | 2025-02-11 | The Boards Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las | Inhibitors of C. difficile spore germination |
| WO2024112631A1 (en) * | 2022-11-22 | 2024-05-30 | Aimmax Therapeutics, Inc. | Streptogramin a monotherapy for treating or preventing bacterial infections |
| EP4418810A1 (de) | 2023-02-15 | 2024-08-21 | Siemens Aktiengesellschaft | Verfahren zur rechnergestützten überwachung einer industriellen anlage mittels eines funknetzes |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3661849A (en) * | 1965-10-06 | 1972-05-09 | Ashland Oil Inc | Heterocyclic polyimides prepared from heterocyclic diamines |
| US3503929A (en) * | 1965-10-21 | 1970-03-31 | Minnesota Mining & Mfg | Polyimidazoquinazolines and polyamidobenzimidazoles |
| DE1670684A1 (de) | 1966-04-01 | 1970-12-03 | Hoechst Ag | Verfahren zur Herstellung von basisch substituierten Bis-benzimidazol-derivaten |
| US4087409A (en) | 1966-11-07 | 1978-05-02 | Monsanto Company | Ordered heterocyclic copolymers |
| JPS50140445A (enExample) * | 1974-04-30 | 1975-11-11 | ||
| JPS50154250A (enExample) * | 1974-05-31 | 1975-12-12 | ||
| US5089592A (en) | 1988-06-09 | 1992-02-18 | The Dow Chemical Company | Biscyclobutarene monomer comprising two cyclobutarene moieties bridged by a divalent radical comprising at least one benzothiazole or benzimidazole linkage |
| JPH03500661A (ja) * | 1988-06-09 | 1991-02-14 | ザ・ダウ・ケミカル・カンパニー | ベンゾキサゾール，ベンゾチアゾールまたはベンズイミダゾールの少なくとも１つの結合によって架橋したビスシクロブタレンのモノマー，オリゴマー及びポリマー |
| GB9108279D0 (en) * | 1991-04-18 | 1991-06-05 | Ucb Sa | A method of preparing 1h-benzimidazoles |
| US5317078A (en) * | 1991-10-30 | 1994-05-31 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Polybenzimidazole via aromatic nucleophilic displacement |
| CN1164227A (zh) * | 1994-11-17 | 1997-11-05 | 弗·哈夫曼-拉罗切有限公司 | 联苯并咪唑衍生物 |
| BR9509671C1 (pt) | 1994-11-17 | 2000-04-18 | Hoffmann La Roche | Derivados de dibenzimidazol |
| US5770617A (en) | 1996-03-20 | 1998-06-23 | Rutgers, The State University Of New Jersey | Terbenzimidazoles useful as antifungal agents |
| JPH11158156A (ja) | 1997-12-03 | 1999-06-15 | Earth Chem Corp Ltd | 新規な１−（４−アルキルオキシフェニル）イミダゾール化合物 |
| JPH11158158A (ja) * | 1997-12-03 | 1999-06-15 | Snow Brand Milk Prod Co Ltd | 新規ベンゾイミダゾール誘導体 |
| US6358930B1 (en) | 1998-05-28 | 2002-03-19 | Synsorb Biotech Inc. | Treatment of C. difficile toxin B associated conditions |
| JP2000095767A (ja) * | 1998-09-28 | 2000-04-04 | Takeda Chem Ind Ltd | 性腺刺激ホルモン放出ホルモン拮抗剤 |
| GB9908828D0 (en) | 1999-04-16 | 1999-06-16 | Univ Reading The | Compounds |
| MXPA03004655A (es) | 2000-11-27 | 2003-09-04 | Ciba Sc Holding Ag | Derivados 5-aril y 5-heteroaril-2-(2-hidroxifenil)-2h-benzotriazol substituidos como absorbentes de uv. |
| MY138797A (en) | 2000-12-15 | 2009-07-31 | Vertex Pharma | Bacterial gyrase inhibitors and uses thereof |
| FR2819180B1 (fr) | 2001-01-11 | 2003-02-21 | Oreal | Composition photoprotectrices a base de polymeres amphiphiles d'au moins un monomere a insaturation ethylique a groupement sulfonique et comportant une partie hydrophobe |
| WO2002060374A2 (en) * | 2001-01-29 | 2002-08-08 | Insight Strategy And Marketing Ltd | Benz-1,3-azole derivatives and their uses as heparanase inhibitors |
| AU2002367953C1 (en) | 2001-05-04 | 2009-02-19 | Paratek Pharmaceuticals, Inc | Transcription factor modulating compounds and methods of use thereof |
| AU2002317377A1 (en) * | 2001-07-20 | 2003-03-03 | Cancer Research Technology Limited | Biphenyl apurinic/apyrimidinic site endonuclease inhibitors to treat cancer |
| JP5039268B2 (ja) | 2001-10-26 | 2012-10-03 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | ベンゾイミダゾールおよび類縁体および蛋白キナーゼ阻害剤としてのその使用 |
| MXPA04012628A (es) | 2002-06-13 | 2005-03-23 | Patricia Olivershaffer | DERIVADOS Y COMPUESTOS RELACIONADOS DEL áCIDO 2-UREIDO-6-HETEROARIL-3H-BENZOIMIDAZOL-4-CARBOXILICO COMO INHIBIDORES DE GIRASA Y/O TOPOISOMERASA IV PARA EL TRATAMIENTO DE INFECCIONES BACTERIALES. |
| US20050260126A1 (en) * | 2002-08-30 | 2005-11-24 | Yukitsuka Kudo | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein |
| CA2504448C (en) | 2002-11-01 | 2012-06-19 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| JP2008504233A (ja) | 2004-04-23 | 2008-02-14 | パラテック ファーマシューティカルズ インコーポレイテッド | 転写因子調節化合物およびその使用法 |
| KR100629060B1 (ko) | 2004-08-11 | 2006-09-26 | 주식회사 엘지화학 | 새로운 벤즈이미다졸계 화합물 |
| ES2354824T3 (es) | 2004-11-04 | 2011-03-18 | Vertex Pharmaceuticals, Inc. | Pirazolo[1,5-a]pirimidinas útiles como inhibidores de proteínas cinasas. |
| CA2594665A1 (en) | 2005-01-19 | 2006-07-27 | Biolipox Ab | Thienopyrroles useful in the treatment of inflammation |
| EP1945209B1 (en) | 2005-08-12 | 2018-05-30 | United States Government As Represented By The Secretary of The United States Army And The U.S. Army Medical Research & Materiel Command | Broad spectrum antibacterial compounds |
| US8394803B2 (en) | 2005-11-07 | 2013-03-12 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| KR100744827B1 (ko) * | 2006-04-05 | 2007-08-01 | 한국화학연구원 | 트리플루오로비닐옥시기를 포함하는 불소계 벤즈이미다졸 단량체 및 이의 제조방법 |
| GB0612428D0 (en) | 2006-06-22 | 2006-08-02 | Prolysis Ltd | Antibacterial agents |
| ES2549862T3 (es) | 2006-08-30 | 2015-11-02 | Cellzome Limited | Derivados de triazol como inhibidores de quinasa |
| PE20080888A1 (es) | 2006-10-18 | 2008-08-26 | Novartis Ag | COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE LA ACIL-TRANSFERASA DE ACIL-CoA-DIACIL-GLICEROL 1 (DGAT1) |
| WO2008073451A2 (en) | 2006-12-11 | 2008-06-19 | Sirtris Pharmaceuticals, Inc. | Benzoimidazole derivatives as sirtuin (sir) modulating compounds |
| US20100029615A1 (en) | 2006-12-15 | 2010-02-04 | Michael John Munchhof | Benzimidazole derivatives |
| EP2280705B1 (en) | 2008-06-05 | 2014-10-08 | Glaxo Group Limited | Novel compounds |
| US7906655B2 (en) | 2008-08-07 | 2011-03-15 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| KR101022649B1 (ko) | 2008-08-07 | 2011-03-22 | 삼성모바일디스플레이주식회사 | 헤테로고리 화합물 및 이를 이용한 유기 전계 발광 장치 |
| GB0821913D0 (en) | 2008-12-02 | 2009-01-07 | Price & Co | Antibacterial compounds |
| ES2606717T3 (es) | 2009-02-27 | 2017-03-27 | Enanta Pharmaceuticals, Inc. | Inhibidores del virus de la hepatitis C |
| KR101219487B1 (ko) | 2009-03-03 | 2013-01-15 | 덕산하이메탈(주) | 비스벤조이미다졸 화합물 및 이를 이용한 유기전기소자, 그단말 |
| ES2548571T3 (es) | 2009-04-02 | 2015-10-19 | Fundación Centro Nacional De Investigaciones Oncológicas Carlos Iii | Derivados de imidazo[2,1-b][1,3,4]tiadiazol |
| EP2435435B1 (en) | 2009-05-27 | 2014-01-29 | AbbVie Inc. | Pyrimidine inhibitors of kinase activity |
| CA2763140A1 (en) | 2009-05-29 | 2010-12-02 | Schering Corporation | Antiviral compounds composed of three linked aryl moieties to treat diseases such as hepatitis c |
| ES2632220T3 (es) | 2009-06-15 | 2017-09-11 | Rigel Pharmaceuticals, Inc. | Inhibidores de moléculas pequeñas de tirosina cinasa del bazo (SYK) |
| JP5819305B2 (ja) | 2009-10-13 | 2015-11-24 | リガンド・ファーマシューティカルズ・インコーポレイテッド | 造血成長因子模倣小分子化合物およびそれらの使用 |
| HRP20160397T1 (hr) | 2010-06-01 | 2016-08-12 | Summit Therapeutics Plc | Spojevi za liječenje clostridium difficile povezanih bolesti |
-
2008
- 2008-12-02 GB GBGB0821913.1A patent/GB0821913D0/en not_active Ceased
-
2009
- 2009-12-01 LT LTEP14197877.5T patent/LT2907813T/lt unknown
- 2009-12-01 DK DK09795514.0T patent/DK2373631T3/en active
- 2009-12-01 WO PCT/GB2009/002792 patent/WO2010063996A2/en not_active Ceased
- 2009-12-01 ES ES09795514.0T patent/ES2537059T3/es active Active
- 2009-12-01 MX MX2011005837A patent/MX2011005837A/es active IP Right Grant
- 2009-12-01 JP JP2011538052A patent/JP5665756B2/ja active Active
- 2009-12-01 BR BRPI0922220A patent/BRPI0922220B8/pt active IP Right Grant
- 2009-12-01 AU AU2009323854A patent/AU2009323854B2/en active Active
- 2009-12-01 HU HUE14197877A patent/HUE029151T2/hu unknown
- 2009-12-01 PL PL14197877.5T patent/PL2907813T3/pl unknown
- 2009-12-01 PT PT97955140T patent/PT2373631E/pt unknown
- 2009-12-01 EP EP16155561.0A patent/EP3095783A1/en not_active Withdrawn
- 2009-12-01 DK DK14197877.5T patent/DK2907813T3/en active
- 2009-12-01 CN CN200980148065.8A patent/CN102227411B/zh active Active
- 2009-12-01 ES ES14197877.5T patent/ES2575908T3/es active Active
- 2009-12-01 SI SI200931456A patent/SI2907813T1/sl unknown
- 2009-12-01 KR KR1020117015273A patent/KR101643435B1/ko active Active
- 2009-12-01 EP EP14197877.5A patent/EP2907813B1/en active Active
- 2009-12-01 BR BR122020013025-3A patent/BR122020013025B1/pt active IP Right Grant
- 2009-12-01 RS RS20160458A patent/RS54904B1/sr unknown
- 2009-12-01 PT PT141978775T patent/PT2907813T/pt unknown
- 2009-12-01 CA CA2744962A patent/CA2744962C/en active Active
- 2009-12-01 SI SI200931191T patent/SI2373631T1/sl unknown
- 2009-12-01 US US13/131,469 patent/US8975416B2/en active Active
- 2009-12-01 SG SG2011040458A patent/SG171939A1/en unknown
- 2009-12-01 HR HRP20150518TT patent/HRP20150518T1/hr unknown
- 2009-12-01 RU RU2011127165/04A patent/RU2525915C2/ru active
- 2009-12-01 PL PL09795514T patent/PL2373631T3/pl unknown
- 2009-12-01 EP EP09795514.0A patent/EP2373631B1/en active Active
- 2009-12-01 NZ NZ593111A patent/NZ593111A/xx unknown
-
2011
- 2011-05-23 ZA ZA2011/03751A patent/ZA201103751B/en unknown
- 2011-06-02 IL IL213325A patent/IL213325A/en active IP Right Grant
-
2014
- 2014-12-09 JP JP2014249071A patent/JP2015078220A/ja active Pending
-
2015
- 2015-02-06 US US14/616,006 patent/US9314456B2/en active Active
- 2015-05-15 CY CY20151100440T patent/CY1116383T1/el unknown
- 2015-05-18 SM SM201500117T patent/SMT201500117B/xx unknown
-
2016
- 2016-03-08 US US15/064,137 patent/US9763925B2/en active Active
- 2016-06-03 HR HRP20160597TT patent/HRP20160597T1/hr unknown
- 2016-06-24 CY CY20161100572T patent/CY1117934T1/el unknown
- 2016-08-03 SM SM201600259T patent/SMT201600259B/it unknown
- 2016-10-28 JP JP2016212160A patent/JP2017048217A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2742007C (en) | Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities | |
| RU2011127165A (ru) | Антибактериальные соединения | |
| JP2014504622A5 (enExample) | ||
| JP2016516043A5 (enExample) | ||
| KR101671761B1 (ko) | 이미다조옥사진 화합물에 의한 항종양 효과 증강제 | |
| MX2010009163A (es) | Derivados heterociclicos de urea y metodos de uso de los mismos-211. | |
| JP2014525420A5 (enExample) | ||
| JP2013533879A5 (enExample) | ||
| JP2010513448A5 (enExample) | ||
| EP3048099A3 (en) | Inhibitors of kinase activity | |
| MX2014015158A (es) | Derivados de piridinona y piridazinona. | |
| JP2016513696A5 (enExample) | ||
| MX2010004244A (es) | Derivados de imidazo [i,2-a]-piridina utiles como inhibidores de cinasa tipo activina (alk). | |
| PH12012501800A1 (en) | 2,3 dihydro- 1h - inden- 1 - yl -2,7 -diazaspirol [ 3.5 ] nonane derivatives and their use as antagonists or inverse agonists of the ghrelin receptor | |
| JP2011500545A5 (enExample) | ||
| JP2017533968A5 (enExample) | ||
| NZ600801A (en) | Substituted imidazopyridinyl-aminopyridine compounds | |
| TNSN07164A1 (en) | Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists | |
| JP2015078220A5 (enExample) | ||
| JP2019512535A5 (enExample) | ||
| JP2016190843A5 (enExample) | ||
| ZA202200660B (en) | Process for the preparation of ridinilazole and crystalline forms thereof | |
| JP2014500296A5 (enExample) | ||
| JP2011517697A5 (enExample) | ||
| MY206359A (en) | Heteroaryl-substituted pyrazole compound and medicinal use thereof |