JP2017531678A5 - - Google Patents
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- JP2017531678A5 JP2017531678A5 JP2017522086A JP2017522086A JP2017531678A5 JP 2017531678 A5 JP2017531678 A5 JP 2017531678A5 JP 2017522086 A JP2017522086 A JP 2017522086A JP 2017522086 A JP2017522086 A JP 2017522086A JP 2017531678 A5 JP2017531678 A5 JP 2017531678A5
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- JP
- Japan
- Prior art keywords
- group
- alkyl
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- groups
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14190073 | 2014-10-23 | ||
| EP14190073.8 | 2014-10-23 | ||
| PCT/EP2015/074431 WO2016062790A1 (en) | 2014-10-23 | 2015-10-22 | New pyrazolopyrimidine derivatives as nik inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531678A JP2017531678A (ja) | 2017-10-26 |
| JP2017531678A5 true JP2017531678A5 (enExample) | 2019-11-21 |
| JP6616412B2 JP6616412B2 (ja) | 2019-12-04 |
Family
ID=51846471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017522086A Expired - Fee Related JP6616412B2 (ja) | 2014-10-23 | 2015-10-22 | Ｎｉｋ阻害剤としての新規のピラゾロピリミジン誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10221180B2 (enExample) |
| EP (1) | EP3209663B1 (enExample) |
| JP (1) | JP6616412B2 (enExample) |
| KR (1) | KR102523405B1 (enExample) |
| CN (1) | CN107074882B (enExample) |
| AU (1) | AU2015334915B2 (enExample) |
| BR (1) | BR112017007704B1 (enExample) |
| CA (1) | CA2960574C (enExample) |
| EA (1) | EA033237B1 (enExample) |
| ES (1) | ES2715104T3 (enExample) |
| IL (1) | IL251778B (enExample) |
| MX (1) | MX371152B (enExample) |
| WO (1) | WO2016062790A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI663166B (zh) | 2013-04-24 | 2019-06-21 | 健生藥品公司 | 新化合物 |
| TWI627173B (zh) | 2013-09-26 | 2018-06-21 | 比利時商健生藥品公司 | 作為ＮＩＫ抑制劑的新穎３－（１Ｈ－吡唑－４－基）－１Ｈ－吡咯并［２，３－ｃ］吡啶衍生物 |
| TWI704146B (zh) | 2013-09-26 | 2020-09-11 | 比利時商健生藥品公司 | 用作ＮＩＫ抑制劑之新的1-(４-嘧啶基)-１Ｈ-吡唑並[３,２-ｃ]吡啶衍生物 |
| EA033238B1 (ru) | 2014-10-23 | 2019-09-30 | Янссен Фармацевтика Нв | Новые производные тиенопиримидина в качестве ингибиторов nik |
| CN107074855B (zh) | 2014-10-23 | 2019-11-05 | 詹森药业有限公司 | 作为nik抑制剂的新的化合物 |
| ES2704749T3 (es) | 2014-10-23 | 2019-03-19 | Janssen Pharmaceutica Nv | Nuevos derivados de pirazol en calidad de inhibidores de nik |
| KR102523405B1 (ko) | 2014-10-23 | 2023-04-18 | 얀센 파마슈티카 엔.브이. | Ｎｉｋ 억제제로서의 신규 피라졸로피리미딘 유도체 |
| CN112839648B (zh) | 2018-06-07 | 2025-04-04 | 达萨玛治疗公司 | Sarm1抑制剂 |
| ES2992431T3 (es) * | 2018-06-18 | 2024-12-12 | Janssen Pharmaceutica Nv | Derivados de pirazol como inhibidores de MALT1 |
| EP3897670A4 (en) | 2018-12-19 | 2022-09-07 | Disarm Therapeutics, Inc. | MRSA1 INHIBITORS IN COMBINATION WITH NEUROPROTECTIVE AGENTS |
| WO2020203950A1 (ja) * | 2019-03-29 | 2020-10-08 | 興和株式会社 | 新規アザインドール誘導体 |
| SMT202400418T1 (it) | 2019-05-31 | 2024-11-15 | Janssen Pharmaceutica Nv | Inibitori a piccola molecola di chinasi che induce nf-κb |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990007926A1 (en) * | 1989-01-20 | 1990-07-26 | Pfizer Inc. | 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines |
| BRPI0510319A (pt) | 2004-04-26 | 2007-10-16 | Pfizer | inibidores da enzima integrase de hiv |
| AR056786A1 (es) | 2005-11-10 | 2007-10-24 | Smithkline Beecham Corp | Compuesto de 1h- imidazo ( 4,5-c) piridin-2-ilo, composicion farmaceutica que lo comprende, procedimiento para preparar dicha composicion, su uso para preparar unmedicamento, uso de una combinacion que omprende al compuesto y al menos un agente antineoplasico para preparar un medicamento y dicha com |
| DE102008005493A1 (de) | 2008-01-22 | 2009-07-23 | Merck Patent Gmbh | 4-(Pyrrolo[2,3-c] pyridine-3-yl)-pyrimidin-2-yl-amin-derivate |
| WO2009158011A1 (en) | 2008-06-26 | 2009-12-30 | Amgen Inc. | Alkynyl alcohols as kinase inhibitors |
| JP2011526931A (ja) | 2008-07-03 | 2011-10-20 | エグゼリクシス， インコーポレイテッド | Ｃｄｋモジュレーター |
| WO2010042337A1 (en) | 2008-10-07 | 2010-04-15 | Merck Sharp & Dohme Corp. | Novel 6-azaindole aminopyrimidine derivatives having nik inhibitory activity |
| CN101723936B (zh) | 2008-10-27 | 2014-01-15 | 上海睿星基因技术有限公司 | 激酶抑制剂及其在药学中的用途 |
| WO2011050245A1 (en) | 2009-10-23 | 2011-04-28 | Yangbo Feng | Bicyclic heteroaryls as kinase inhibitors |
| CA2827161A1 (en) | 2011-03-16 | 2012-09-20 | F. Hoffmann-La Roche Ag | 6,5-heterocyclic propargylic alcohol compounds and uses therefor |
| TWI663166B (zh) | 2013-04-24 | 2019-06-21 | 健生藥品公司 | 新化合物 |
| TWI627173B (zh) | 2013-09-26 | 2018-06-21 | 比利時商健生藥品公司 | 作為ＮＩＫ抑制劑的新穎３－（１Ｈ－吡唑－４－基）－１Ｈ－吡咯并［２，３－ｃ］吡啶衍生物 |
| TWI704146B (zh) | 2013-09-26 | 2020-09-11 | 比利時商健生藥品公司 | 用作ＮＩＫ抑制劑之新的1-(４-嘧啶基)-１Ｈ-吡唑並[３,２-ｃ]吡啶衍生物 |
| EA033238B1 (ru) | 2014-10-23 | 2019-09-30 | Янссен Фармацевтика Нв | Новые производные тиенопиримидина в качестве ингибиторов nik |
| CN107074855B (zh) | 2014-10-23 | 2019-11-05 | 詹森药业有限公司 | 作为nik抑制剂的新的化合物 |
| ES2704749T3 (es) | 2014-10-23 | 2019-03-19 | Janssen Pharmaceutica Nv | Nuevos derivados de pirazol en calidad de inhibidores de nik |
| KR102523405B1 (ko) | 2014-10-23 | 2023-04-18 | 얀센 파마슈티카 엔.브이. | Ｎｉｋ 억제제로서의 신규 피라졸로피리미딘 유도체 |
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2015
- 2015-10-22 KR KR1020177010805A patent/KR102523405B1/ko active Active
- 2015-10-22 MX MX2017005284A patent/MX371152B/es active IP Right Grant
- 2015-10-22 EP EP15784050.5A patent/EP3209663B1/en active Active
- 2015-10-22 WO PCT/EP2015/074431 patent/WO2016062790A1/en not_active Ceased
- 2015-10-22 BR BR112017007704-3A patent/BR112017007704B1/pt not_active IP Right Cessation
- 2015-10-22 CN CN201580057545.9A patent/CN107074882B/zh not_active Expired - Fee Related
- 2015-10-22 JP JP2017522086A patent/JP6616412B2/ja not_active Expired - Fee Related
- 2015-10-22 AU AU2015334915A patent/AU2015334915B2/en not_active Ceased
- 2015-10-22 CA CA2960574A patent/CA2960574C/en active Active
- 2015-10-22 EA EA201790907A patent/EA033237B1/ru not_active IP Right Cessation
- 2015-10-22 ES ES15784050T patent/ES2715104T3/es active Active
- 2015-10-22 US US15/520,346 patent/US10221180B2/en active Active
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2017
- 2017-04-19 IL IL251778A patent/IL251778B/en active IP Right Grant
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2019
- 2019-02-01 US US16/265,679 patent/US10822342B2/en active Active