JP2016507575A5 - - Google Patents

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JP2016507575A5
JP2016507575A5 JP2015557226A JP2015557226A JP2016507575A5 JP 2016507575 A5 JP2016507575 A5 JP 2016507575A5 JP 2015557226 A JP2015557226 A JP 2015557226A JP 2015557226 A JP2015557226 A JP 2015557226A JP 2016507575 A5 JP2016507575 A5 JP 2016507575A5
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compound
compound according
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alzheimer
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JP6471100B2 (ja
JP2016507575A (ja
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Priority claimed from PCT/US2014/016100 external-priority patent/WO2014127042A1/en
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JP2015557226A 2013-02-12 2014-02-12 Ｂａｃｅ仲介性ａｐｐプロセシングを調節するヒダントイン Active JP6471100B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361763830P 2013-02-12 2013-02-12
US61/763,830 2013-02-12
PCT/US2014/016100 WO2014127042A1 (en) 2013-02-12 2014-02-12 Hydantoins that modulate bace-mediated app processing

Related Child Applications (1)

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JP2019005905A Division JP6773820B2 (ja) 2013-02-12 2019-01-17 Ｂａｃｅ仲介性ａｐｐプロセシングを調節するヒダントイン

Publications (3)

Publication Number Publication Date
JP2016507575A JP2016507575A (ja) 2016-03-10
JP2016507575A5 true JP2016507575A5 (enExample) 2017-02-23
JP6471100B2 JP6471100B2 (ja) 2019-02-13

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JP2015557226A Active JP6471100B2 (ja) 2013-02-12 2014-02-12 Ｂａｃｅ仲介性ａｐｐプロセシングを調節するヒダントイン
JP2019005905A Active JP6773820B2 (ja) 2013-02-12 2019-01-17 Ｂａｃｅ仲介性ａｐｐプロセシングを調節するヒダントイン

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JP2019005905A Active JP6773820B2 (ja) 2013-02-12 2019-01-17 Ｂａｃｅ仲介性ａｐｐプロセシングを調節するヒダントイン

Country Status (11)

Country Link
US (6) US20140371283A1 (enExample)
EP (2) EP3653609B1 (enExample)
JP (2) JP6471100B2 (enExample)
KR (2) KR102220259B1 (enExample)
CN (1) CN104995176B (enExample)
AU (1) AU2014216390B2 (enExample)
CA (1) CA2899938C (enExample)
DK (1) DK2956443T3 (enExample)
ES (2) ES2975235T3 (enExample)
IL (1) IL240555B (enExample)
WO (1) WO2014127042A1 (enExample)

Families Citing this family (13)

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CA2899938C (en) 2013-02-12 2021-10-19 Buck Institute For Research On Aging Hydantoins that modulate bace-mediated app processing
AU2016220049C1 (en) 2015-02-18 2021-02-25 Buck Institute For Research On Aging Triazolopyridines and triazolopyrimidines that lower stress-induced p-tau
KR20180090778A (ko) 2015-08-27 2018-08-13 난트뉴로, 엘엘씨 App-선택적 bace 억제를 위한 조성물 및 그의 용도
WO2017096049A1 (en) 2015-12-03 2017-06-08 The University Of North Carolina At Pembroke Materials for cathepsin b enhancement and methods of use
US10532102B2 (en) 2016-08-19 2020-01-14 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical composition and methods of uses
CA3034032C (en) * 2016-08-19 2021-05-25 Foresee Pharmaceuticals Co., Ltd. Compositions comprising inhibitors of macrophage elastase and cyclodextrin
CN107353239B (zh) 2017-08-11 2019-06-18 北京卓凯生物技术有限公司 4-氧-烷基化特特拉姆酸类化合物及其制备方法
CN107468690B (zh) 2017-08-11 2020-01-31 北京卓凯生物技术有限公司 4-氧-烷基化特特拉姆酸类化合物及其制备方法与应用
US20210101879A1 (en) * 2018-03-01 2021-04-08 The Regents Of The University Of California AMYLOID PROTEIN-SELECTIVE BACE INHIBITORS (ASBIs) FOR ALZHEIMER?S DISEASE
CN110652516A (zh) * 2018-06-29 2020-01-07 上海绿谷制药有限公司 甘露糖醛二酸的组合物在治疗帕金森氏症中的应用
US12208027B2 (en) 2018-12-04 2025-01-28 The Brain Protection Company PTY LTD Combinatorial therapies including implantable damping devices and therapeutic agents for treating a condition and associated systems and methods of use
EP3890618A4 (en) * 2018-12-04 2023-01-11 The Brain Protection Company PTY Ltd COMBINATIONAL THERAPIES COMPRISING IMPLANTABLE DAMPING DEVICES AND THERAPEUTIC AGENTS FOR TREATING A CONDITION AND SYSTEMS AND METHODS OF USE THEREOF
US11926599B1 (en) 2023-10-23 2024-03-12 King Faisal University 1-(2-chlorobenzylideneamino)-5,5-diphenylimidazolidine-2,4-dione as an antimicrobial compound

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