|
EP0996725A1
(en)
*
|
1997-06-27 |
2000-05-03 |
Human Genome Sciences, Inc. |
Human nk-3 related prostate specific gene-1
|
|
PE20020132A1
(es)
*
|
2000-06-29 |
2002-03-04 |
Abbott Lab |
Anticuerpos de especificidad doble y metodos para la elaboracion y el uso de los mismos
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
GB0115841D0
(en)
|
2001-06-28 |
2001-08-22 |
Medical Res Council |
Ligand
|
|
JP4303105B2
(ja)
*
|
2001-06-28 |
2009-07-29 |
ドマンティス リミテッド |
二重特異性リガンドとその利用
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
US20060002935A1
(en)
|
2002-06-28 |
2006-01-05 |
Domantis Limited |
Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor
|
|
US7696320B2
(en)
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
|
US9028822B2
(en)
|
2002-06-28 |
2015-05-12 |
Domantis Limited |
Antagonists against TNFR1 and methods of use therefor
|
|
US20070104710A1
(en)
*
|
2002-06-28 |
2007-05-10 |
Domants Limited |
Ligand that has binding specificity for IL-4 and/or IL-13
|
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
NZ537277A
(en)
|
2002-07-18 |
2008-04-30 |
Crucell Holland Bv |
Recombinant production of mixtures of antibodies
|
|
US20050271660A1
(en)
|
2002-09-06 |
2005-12-08 |
Alexion Pharmaceuticals, Inc. |
Nebulization of monoclonal antibodies for treating pulmonary diseases
|
|
GB0230201D0
(en)
*
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Retargeting
|
|
US20110223168A1
(en)
*
|
2002-12-27 |
2011-09-15 |
Greg Winter |
Ligand that has binding specificity for il-4 and/or il-13
|
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
US7981843B2
(en)
*
|
2004-01-20 |
2011-07-19 |
Kalobios Pharmaceuticals, Inc. |
Antibody specificity transfer using minimal essential binding determinants
|
|
EP1737971B1
(en)
|
2004-01-20 |
2017-08-16 |
Merus N.V. |
Mixtures of binding proteins
|
|
TWI439284B
(zh)
|
2004-04-09 |
2014-06-01 |
艾伯維生物技術有限責任公司 |
用於治療ＴＮＦα相關失調症之多重可變劑量療法
|
|
SI1747015T1
(sl)
*
|
2004-04-26 |
2012-11-30 |
Janssen Biotech Inc |
Postopek biopanninga raztopinske faze z uporabo genetsko proizvedenih vabnih proteinov
|
|
US7790405B2
(en)
|
2004-04-26 |
2010-09-07 |
Centocor, Inc. |
Solution phase biopanning method using engineered decoy proteins
|
|
US7514539B2
(en)
|
2004-04-26 |
2009-04-07 |
Centocor, Inc. |
Epitope directed selection of antibodies to murine tissue factor
|
|
US8921528B2
(en)
|
2004-06-01 |
2014-12-30 |
Domantis Limited |
Bispecific fusion antibodies with enhanced serum half-life
|
|
KR20070084069A
(ko)
|
2004-10-08 |
2007-08-24 |
도만티스 리미티드 |
Ｔｎｆｒ1에 대한 단일 도메인 항체 및 이의 사용 방법
|
|
EP2361933A3
(en)
|
2005-01-26 |
2012-05-02 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
KR100675791B1
(ko)
*
|
2005-02-04 |
2007-02-02 |
제주대학교 산학협력단 |
육상어류양식장용 자동먹이공급시스템
|
|
CA2608058C
(en)
|
2005-05-12 |
2013-09-10 |
Crucell Holland B.V. |
Host cell specific binding molecules capable of neutralizing viruses and uses thereof
|
|
WO2006136601A1
(en)
*
|
2005-06-23 |
2006-12-28 |
Crucell Holland B.V. |
Optimization of west nile virus antibodies
|
|
AU2006272555B2
(en)
|
2005-07-25 |
2012-03-08 |
Aptevo Research And Development Llc |
B-cell reduction using CD37-specific and CD20-specific binding molecules
|
|
EP2500353A3
(en)
|
2005-08-19 |
2012-10-10 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
KR20140053410A
(ko)
|
2005-08-19 |
2014-05-07 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
CN101277974A
(zh)
|
2005-09-30 |
2008-10-01 |
阿伯特有限及两合公司 |
排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
|
|
EP1940880A2
(en)
*
|
2005-10-14 |
2008-07-09 |
Novo Nordisk A/S |
Treating diabetes using inhibitors of il-1
|
|
KR20110079922A
(ko)
*
|
2006-04-14 |
2011-07-11 |
노파르티스 아게 |
안과 장애 치료를 위한 ｉｌ－1 항체의 용도
|
|
DK2027155T3
(en)
*
|
2006-06-06 |
2016-05-09 |
Crucell Holland Bv |
HUMAN BINDING MOLECULES with killer activity against staphylococci and uses thereof
|
|
CN105837690A
(zh)
|
2006-06-12 |
2016-08-10 |
新兴产品开发西雅图有限公司 |
具有效应功能的单链多价结合蛋白
|
|
EP2069534A4
(en)
*
|
2006-08-02 |
2010-08-11 |
California Inst Of Techn |
METHOD AND SYSTEMS FOR DETECTING AND / OR SORTING TARGETS
|
|
EP2471816A1
(en)
*
|
2006-08-30 |
2012-07-04 |
Genentech, Inc. |
Multispecific antibodies
|
|
WO2008077145A2
(en)
*
|
2006-12-20 |
2008-06-26 |
Xoma Technology Ltd. |
Treatment of il-1-beta related diseases
|
|
WO2008082651A2
(en)
*
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Dual-specific il-1a/ il-1b antibodies
|
|
EP2165194A4
(en)
|
2007-05-31 |
2010-09-08 |
Abbott Lab |
BIOMARKERS FOR PREDICTING RESPONSABILITY TO TNF ALPHA INHIBITORS IN AUTOIMMUNE DISEASES
|
|
EP2535350B1
(en)
|
2007-09-26 |
2018-01-24 |
UCB Biopharma SPRL |
Dual specificity antibody fusions
|
|
CA2707637A1
(en)
|
2007-12-17 |
2009-06-25 |
Dyax Corp. |
Compositions and methods for treating osteolytic disorders comprising mmp-14 binding proteins
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
US8013125B2
(en)
*
|
2008-03-03 |
2011-09-06 |
Dyax Corp. |
Metalloproteinase 9 and metalloproteinase 2 binding proteins
|
|
JP2011517662A
(ja)
|
2008-03-03 |
2011-06-16 |
ダイアックス コーポレーション |
メタロプロテアーゼ９結合タンパク質
|
|
NZ603059A
(en)
|
2008-04-11 |
2014-07-25 |
Emergent Product Dev Seattle |
Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
|
EP2282769A4
(en)
*
|
2008-04-29 |
2012-04-25 |
Abbott Lab |
DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES
|
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
EP2297209A4
(en)
*
|
2008-06-03 |
2012-08-01 |
Abbott Lab |
IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF
|
|
KR20110016959A
(ko)
*
|
2008-06-03 |
2011-02-18 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
US8822645B2
(en)
*
|
2008-07-08 |
2014-09-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
|
AR073538A1
(es)
|
2008-09-03 |
2010-11-17 |
Genentech Inc |
Anticuerpos multiespecificos que se unen especificamente al receptor del factor de crecimiento epidermico humano 2 (her2) y al factor de crecimiento endotelial vascular (vegf)
|
|
AU2009289547A1
(en)
*
|
2008-09-05 |
2010-03-11 |
Xoma (Us) Llc |
Methods for treating or preventing IL-1beta related diseases
|
|
JP5976319B2
(ja)
*
|
2008-09-12 |
2016-08-23 |
エックスバイオテク, インコーポレイテッドXbiotech, Inc. |
病原性単球の標的化
|
|
US10407513B2
(en)
|
2008-09-26 |
2019-09-10 |
Ucb Biopharma Sprl |
Biological products
|
|
EP2196476A1
(en)
*
|
2008-12-10 |
2010-06-16 |
Novartis Ag |
Antibody formulation
|
|
NZ593905A
(en)
*
|
2009-01-29 |
2013-03-28 |
Abbott Lab |
Il-1 binding proteins
|
|
NZ594514A
(en)
|
2009-03-05 |
2013-06-28 |
Abbott Lab |
Interleukin-17 BINDING PROTEINS
|
|
BRPI1014089A2
(pt)
*
|
2009-04-02 |
2016-04-19 |
Roche Glycart Ag |
anticorpos multiespecíficos que compreendem anticorpos de comprimento completo e fragmentos fab de cadeia simples
|
|
CN101957365B
(zh)
*
|
2009-07-21 |
2013-08-07 |
卫生部北京医院 |
检测抗环瓜氨酸肽和抗免疫球蛋白g双特异性抗体的试剂盒
|
|
TW201109438A
(en)
*
|
2009-07-29 |
2011-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
CA2771575A1
(en)
|
2009-08-29 |
2011-03-03 |
Abbott Laboratories |
Therapeutic dll4 binding proteins
|
|
MX2012002651A
(es)
|
2009-09-01 |
2012-05-22 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
|
AR078651A1
(es)
*
|
2009-10-15 |
2011-11-23 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
AU2010306681A1
(en)
*
|
2009-10-15 |
2012-04-19 |
Abbvie Inc. |
IL-1 binding proteins
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
PH12012501070A1
(en)
|
2009-12-08 |
2017-08-23 |
Abbott Gmbh & Co Kg |
Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
|
|
EP2523974A4
(en)
*
|
2010-01-12 |
2013-11-06 |
Oncomed Pharm Inc |
WNT BINDER AND APPLICATIONS THEREOF
|
|
WO2011109298A2
(en)
|
2010-03-02 |
2011-09-09 |
Abbott Laboratories |
Therapeutic dll4 binding proteins
|
|
WO2011133886A2
(en)
|
2010-04-23 |
2011-10-27 |
Genentech, Inc. |
Production of heteromultimeric proteins
|
|
TWI500427B
(zh)
|
2010-05-14 |
2015-09-21 |
Abbvie Inc |
Ｉｌ－１結合蛋白
|
|
US20120009196A1
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
KR20130100118A
(ko)
|
2010-08-03 |
2013-09-09 |
아비에 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
CN104474546A
(zh)
*
|
2010-08-13 |
2015-04-01 |
弗·哈夫曼-拉罗切有限公司 |
用于疾病治疗的针对IL-1β和IL-18的抗体
|
|
US9046513B2
(en)
|
2010-08-26 |
2015-06-02 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
MX2013007332A
(es)
|
2010-12-21 |
2014-01-23 |
Abbvie Inc |
Inmunoglobulinas de dominio variable doble biespecificas de il-1 alfa y beta y su uso.
|
|
RU2563830C2
(ru)
|
2011-02-08 |
2015-09-20 |
Эббви Инк. |
Лечение остеоартрита и боли
|
|
US20140255405A1
(en)
|
2011-05-27 |
2014-09-11 |
Dutalys |
Removal of Monomeric Targets
|
|
SG195196A1
(en)
|
2011-05-27 |
2013-12-30 |
Dutalys |
Dual targeting
|
|
WO2012176779A1
(ja)
|
2011-06-20 |
2012-12-27 |
協和発酵キリン株式会社 |
抗ｅｒｂＢ３抗体
|
|
US10314909B2
(en)
|
2011-10-21 |
2019-06-11 |
Dyax Corp. |
Combination therapy comprising an MMP-14 binding protein
|
|
AR088513A1
(es)
|
2011-10-24 |
2014-06-18 |
Abbvie Inc |
Inmunoenlazantes dirigidos contra esclerostina
|
|
UY34410A
(es)
|
2011-10-24 |
2013-05-31 |
Abbvie Inc |
Inmunoligantes biespecificos dirigidos contra tnf
|
|
US20140348838A1
(en)
*
|
2011-11-21 |
2014-11-27 |
Abbvie Inc. |
Il-1 binding proteins
|
|
RU2482181C1
(ru)
*
|
2011-12-07 |
2013-05-20 |
Учреждение Российской академии медицинских наук Российский онкологический научный центр имени Н.Н. Блохина РАМН |
Клеточная линия d11 множественной миеломы человека, используемая для гибридомной технологии
|
|
MX357708B
(es)
|
2011-12-14 |
2018-07-20 |
Abbvie Deutschland |
Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro.
|
|
CN104136462B
(zh)
|
2011-12-14 |
2017-06-09 |
艾伯维德国有限责任两合公司 |
用于诊断和治疗铁相关病症的组合物和方法
|
|
KR101963230B1
(ko)
|
2011-12-26 |
2019-03-29 |
삼성전자주식회사 |
복수개의 단일 항체를 포함하는 단백질 복합체
|
|
WO2013101972A2
(en)
|
2011-12-30 |
2013-07-04 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
AR089529A1
(es)
|
2011-12-30 |
2014-08-27 |
Abbvie Inc |
Proteinas de union especificas duales dirigidas contra il-13 y/o il-17
|
|
AU2013211939C1
(en)
|
2012-01-27 |
2018-06-07 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
|
GB2502127A
(en)
|
2012-05-17 |
2013-11-20 |
Kymab Ltd |
Multivalent antibodies and in vivo methods for their production
|
|
WO2013157953A1
(en)
|
2012-04-20 |
2013-10-24 |
Merus B.V. |
Methods and means for the production of ig-like molecules
|
|
AR091755A1
(es)
|
2012-07-12 |
2015-02-25 |
Abbvie Inc |
Proteinas de union a il-1
|
|
KR101911438B1
(ko)
|
2012-10-31 |
2018-10-24 |
삼성전자주식회사 |
이중 특이 항원 결합 단백질 복합체 및 이중 특이 항체의 제조 방법
|
|
TW201838651A
(zh)
*
|
2012-11-01 |
2018-11-01 |
美商艾伯維有限公司 |
穩定雙重可變區域免疫球蛋白蛋白質調配物
|
|
PE20151179A1
(es)
|
2012-11-01 |
2015-09-12 |
Abbvie Inc |
Inmunoglobulinas de dominio variable dual anti-vegf/dll4 y usos de las mismas
|
|
WO2014089209A2
(en)
|
2012-12-04 |
2014-06-12 |
Abbvie, Inc. |
Blood-brain barrier (bbb) penetrating dual specific binding proteins
|
|
US9856319B2
(en)
|
2012-12-28 |
2018-01-02 |
Abbvie Inc. |
Monovalent binding proteins
|
|
EP2938637A2
(en)
|
2012-12-28 |
2015-11-04 |
AbbVie Inc. |
Multivalent binding protein compositions
|
|
US20140219913A1
(en)
*
|
2012-12-28 |
2014-08-07 |
Abbvie, Inc. |
Dual Specific Binding Proteins Having a Receptor Sequence
|
|
EP2948475A2
(en)
|
2013-01-23 |
2015-12-02 |
AbbVie Inc. |
Methods and compositions for modulating an immune response
|
|
AU2014227732A1
(en)
|
2013-03-15 |
2015-09-17 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-1 beta and IL-17
|
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
|
CA2904407A1
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Inc. |
Dual specific binding proteins directed against tnf.alpha.
|
|
EP3003372B1
(en)
|
2013-06-07 |
2019-10-09 |
Duke University |
Inhibitors of complement factor h
|
|
CN103308697B
(zh)
*
|
2013-06-09 |
2014-11-26 |
卫生部北京医院 |
检测抗丙型肝炎病毒编码的非结构蛋白ns3和ns5的天然双特异性抗体的试剂盒
|
|
US9879081B2
(en)
|
2013-06-25 |
2018-01-30 |
Samsung Electronics Co., Ltd. |
Protein complex, bispecific antibody including the protein complex, and method of preparation thereof
|
|
US20160271230A1
(en)
|
2013-09-17 |
2016-09-22 |
University Health Network (Uhn): Technology Development And Commercialization |
Agents directed against a cis rgma/neogenin interaction or lipid rafts and use of the same in methods of treatment
|
|
MX2016003617A
(es)
*
|
2013-09-30 |
2016-07-21 |
Chugai Pharmaceutical Co Ltd |
Metodo para producir molecula de enlace al antigeno usando fago auxiliar modificado.
|
|
BR112016011027A2
(pt)
*
|
2013-12-20 |
2017-12-05 |
Genentech Inc |
método de produção de um anticorpo, anticorpos, composição farmacêutica, polinucleotídeo, vetor, célula hospedeira, método de tratamento de asma e método de tratamento de um distúrbio
|
|
PL3140392T3
(pl)
|
2014-05-06 |
2023-11-27 |
F. Hoffmann-La Roche Ag |
Produkcja białek heteromultimerycznych z wykorzystaniem komórek ssaków
|
|
WO2015191783A2
(en)
|
2014-06-10 |
2015-12-17 |
Abbvie Inc. |
Biomarkers for inflammatory disease and methods of using same
|
|
WO2015191934A2
(en)
|
2014-06-11 |
2015-12-17 |
Abbvie Inc. |
Blood-brain barrier (bbb) penetrating dual specific binding proteins for treating brain and neurological diseases
|
|
EP2985294A1
(en)
|
2014-08-14 |
2016-02-17 |
Deutsches Krebsforschungszentrum |
Recombinant antibody molecule and its use for target cell restricted T cell activation
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
JP6655302B2
(ja)
*
|
2015-05-29 |
2020-02-26 |
デンカ生研株式会社 |
被検対象の検出方法並びにそのための免疫測定器具及びモノクローナル抗体
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
CA2998183A1
(en)
|
2015-09-11 |
2017-03-16 |
AbbVie Deutschland GmbH & Co. KG |
Methods for treating relapsing forms of multiple sclerosis
|
|
HK1251480A1
(zh)
|
2015-09-21 |
2019-02-01 |
Aptevo Research And Development Llc |
Cd3结合多肽
|
|
CN108139394B
(zh)
*
|
2015-10-02 |
2020-10-30 |
豪夫迈·罗氏有限公司 |
用于确定同时结合的基于细胞的fret测定法
|
|
MA43028B1
(fr)
|
2015-10-02 |
2021-09-30 |
Hoffmann La Roche |
Anticorps bispécifiques pour pd1 et tim3
|
|
WO2017087784A1
(en)
|
2015-11-18 |
2017-05-26 |
Duke University |
Tumor infiltrating lymphocytes for treatment of cancer
|
|
ES2951648T3
(es)
|
2016-03-11 |
2023-10-24 |
Scholar Rock Inc |
Inmunoglobulinas de unión a Tgfbeta1 y uso de las mismas
|
|
TW202523689A
(zh)
|
2016-06-01 |
2025-06-16 |
美商艾伯維有限公司 |
治療脊髓損傷及疼痛之方法
|
|
EP3515494B1
(en)
|
2016-09-26 |
2026-02-25 |
The Brigham and Women's Hospital, Inc. |
Regulators of b cell-mediated immunosuppression
|
|
CA3036714A1
(en)
|
2016-10-03 |
2018-04-12 |
Abbott Laboratories |
Improved methods of assessing uch-l1 status in patient samples
|
|
CN110382530A
(zh)
|
2017-01-06 |
2019-10-25 |
供石公司 |
亚型特异性、背景许可性TGFβ1抑制剂及其用途
|
|
JP7346300B2
(ja)
|
2017-03-23 |
2023-09-19 |
アボット・ラボラトリーズ |
早期バイオマーカーであるユビキチンカルボキシ末端ヒドロラーゼｌ１を使用する、ヒト対象における外傷性脳損傷の程度の診断及び決定の一助となるための方法
|
|
KR102461885B1
(ko)
|
2017-04-03 |
2022-11-03 |
에프. 호프만-라 로슈 아게 |
항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체
|
|
CA3052532A1
(en)
|
2017-04-05 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specifically binding to pd1 and lag3
|
|
EP3610268B1
(en)
|
2017-04-15 |
2025-09-24 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
|
|
JP7080899B2
(ja)
|
2017-04-28 |
2022-06-06 |
アボット・ラボラトリーズ |
同じヒト対象に由来する少なくとも２つの試料に対して早期バイオマーカーを使用する、外傷性脳損傷の超急性の診断及び決定の一助となるための方法
|
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
|
US10866251B2
(en)
|
2017-05-25 |
2020-12-15 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
|
WO2018222783A1
(en)
|
2017-05-30 |
2018-12-06 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a mild traumatic brain injury in a human subject using cardiac troponin i and early biomarkers
|
|
EP3649474A1
(en)
|
2017-07-03 |
2020-05-13 |
Abbott Laboratories |
Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood
|
|
GB201711208D0
(en)
|
2017-07-12 |
2017-08-23 |
Iontas Ltd |
Ion channel inhibitors
|
|
AU2018363922B2
(en)
|
2017-11-08 |
2025-06-12 |
Kyowa Kirin Co., Ltd. |
Bispecific antibody which binds to CD40 and EpCAM
|
|
WO2019113525A2
(en)
|
2017-12-09 |
2019-06-13 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
|
|
WO2019112860A1
(en)
|
2017-12-09 |
2019-06-13 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of gfap and uch-l1
|
|
WO2019133717A1
(en)
|
2017-12-29 |
2019-07-04 |
Abbott Laboratories |
Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury
|
|
KR102891320B1
(ko)
|
2018-07-11 |
2025-11-28 |
스칼러 락, 인크. |
고친화도, 이소형-선택적 TGFβ1 억제제 및 그의 용도
|
|
EP3820896A1
(en)
|
2018-07-11 |
2021-05-19 |
Scholar Rock, Inc. |
TGFbeta1 INHIBITORS AND USE THEREOF
|
|
PT3677278T
(pt)
|
2018-07-11 |
2022-02-03 |
Scholar Rock Inc |
Inibidores seletivos da isoforma tgfbeta1 e sua utilização
|
|
KR102991359B1
(ko)
|
2018-12-28 |
2026-07-16 |
쿄와 기린 가부시키가이샤 |
TfR에 결합하는 이중 특이적 항체
|
|
WO2020180695A1
(en)
|
2019-03-01 |
2020-09-10 |
Abbott Laboratories |
Methods for predicting major adverse cardiovascular events in subjects with coronary artery disease
|
|
WO2020230901A1
(ja)
|
2019-05-15 |
2020-11-19 |
協和キリン株式会社 |
Ｃｄ４０とｇｐｃ３に結合するバイスペシフィック抗体
|
|
CA3140385A1
(en)
|
2019-05-15 |
2020-11-19 |
Kyowa Kirin Co., Ltd. |
Bispecific antibody binding to cd40 and fap
|
|
CA3166328A1
(en)
|
2020-01-11 |
2021-07-15 |
Scholar Rock, Inc. |
Tgf-beta inhibitors and use thereof
|
|
CA3167427A1
(en)
|
2020-01-11 |
2021-07-15 |
Scholar Rock, Inc. |
Tgfb inhibitors and use thereof
|
|
CA3175523A1
(en)
|
2020-04-13 |
2021-10-21 |
Antti Virtanen |
Methods, complexes and kits for detecting or determining an amount of a .beta.-coronavirus antibody in a sample
|
|
CN111793131A
(zh)
*
|
2020-05-11 |
2020-10-20 |
廊坊天光生物技术有限公司 |
一种用于检测血清中pf4含量的抗体对及其用途
|
|
AU2021273014A1
(en)
|
2020-05-13 |
2022-11-17 |
AbbVie Deutschland GmbH & Co. KG |
Anti-hemojuvelin (HJV) antibodies for treating anemia of chronic disease
|
|
ES3075793T3
(en)
|
2020-05-13 |
2026-08-07 |
Disc Medicine Inc |
Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
|
|
US20220043000A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Laboratories |
Methods and kits for detecting sars-cov-2 protein in a sample
|
|
WO2022119841A1
(en)
|
2020-12-01 |
2022-06-09 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2022147147A1
(en)
|
2020-12-30 |
2022-07-07 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
|
WO2022204581A2
(en)
|
2021-03-26 |
2022-09-29 |
Scholar Rock, Inc. |
Tgf-beta inhibitors and use thereof
|
|
AU2022279156A1
(en)
|
2021-05-18 |
2023-11-02 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
|
EP4348260A2
(en)
|
2021-06-03 |
2024-04-10 |
Scholar Rock, Inc. |
Tgf-beta inhibitors and therapeutic use thereof
|
|
WO2022266034A1
(en)
|
2021-06-14 |
2022-12-22 |
Abbott Laboratories |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
|
EP4370148A1
(en)
|
2021-07-14 |
2024-05-22 |
Scholar Rock, Inc. |
Ltbp complex-specific inhibitors of tgf beta1 and uses thereof
|
|
WO2023019019A2
(en)
*
|
2021-08-13 |
2023-02-16 |
Abwiz Bio, Inc. |
Humanization, affinity maturation, and optimization methods for proteins and antibodies
|
|
CN118715440A
(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
|
CA3230038A1
(en)
|
2021-08-31 |
2023-03-09 |
Hongwei Zhang |
Methods and systems of diagnosing brain injury
|
|
WO2023056268A1
(en)
|
2021-09-30 |
2023-04-06 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
JP2025503439A
(ja)
|
2021-12-17 |
2025-02-04 |
アボット・ラボラトリーズ |
血液試料におけるｕｃｈ－ｌ１、ｇｆａｐ及び他のバイオマーカーを決定するためのシステム及び方法
|
|
JP2025507303A
(ja)
|
2022-02-04 |
2025-03-18 |
アボット・ラボラトリーズ |
試料におけるユビキチンカルボキシ末端ヒドロラーゼｌ１及び／又はグリア原線維性酸性タンパク質の存在を検出する又はその量を測定するためのラテラルフロー方法、アッセイ及びデバイス
|
|
WO2024006876A1
(en)
|
2022-06-29 |
2024-01-04 |
Abbott Laboratories |
Magnetic point-of-care systems and assays for determining gfap in biological samples
|
|
AU2023342055A1
(en)
|
2022-09-15 |
2025-03-13 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
|
EP4676954A1
(en)
|
2023-03-07 |
2026-01-14 |
Scholar Rock, Inc. |
Tgf-beta inhibitors for use for treating resistant or unresponsive cancer in patients
|
|
JP2026517628A
(ja)
|
2023-04-04 |
2026-06-02 |
アボット・ラボラトリーズ |
対象が亜急性後天性脳損傷（ａｂｉ）を負った、負った可能性がある、又は負っていると推測されるかどうかを決定するためのバイオマーカーの使用
|
|
WO2024226971A1
(en)
|
2023-04-28 |
2024-10-31 |
Abbott Point Of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|
|
AU2024386429A1
(en)
|
2023-11-22 |
2026-05-21 |
Mabylon Ag |
Multispecific anti-allergen antibodies and uses thereof
|
|
AU2023474055A1
(en)
|
2023-11-23 |
2026-06-04 |
Mabylon Ag |
Multispecific anti-allergen antibodies and uses thereof
|
|
WO2025230857A1
(en)
|
2024-05-01 |
2025-11-06 |
Abbott Laboratories |
Improved methods for determining cardiac myosin binding protein c in biological samples
|
|
WO2026112563A1
(en)
|
2024-11-25 |
2026-05-28 |
Abbott Laboratories |
Systems and methods for tbi adjudication
|
|
WO2026152042A1
(en)
|
2025-01-10 |
2026-07-16 |
Scholar Rock, Inc. |
A novel class of musk agonists and uses thereof
|