|
EP0996725A1
(en)
*
|
1997-06-27 |
2000-05-03 |
Human Genome Sciences, Inc. |
Human nk-3 related prostate specific gene-1
|
|
SK1152003A3
(en)
*
|
2000-06-29 |
2003-07-01 |
Abbott Lab |
Dual specificity antibodies and methods of making and using
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
DK1399484T3
(da)
*
|
2001-06-28 |
2010-11-08 |
Domantis Ltd |
Dobbelt-specifik ligand og anvendelse af denne
|
|
GB0115841D0
(en)
|
2001-06-28 |
2001-08-22 |
Medical Res Council |
Ligand
|
|
US20070104710A1
(en)
*
|
2002-06-28 |
2007-05-10 |
Domants Limited |
Ligand that has binding specificity for IL-4 and/or IL-13
|
|
US20060002935A1
(en)
|
2002-06-28 |
2006-01-05 |
Domantis Limited |
Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor
|
|
US7696320B2
(en)
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
US9028822B2
(en)
|
2002-06-28 |
2015-05-12 |
Domantis Limited |
Antagonists against TNFR1 and methods of use therefor
|
|
CN105884893A
(zh)
|
2002-07-18 |
2016-08-24 |
莫鲁斯有限公司 |
抗体混合物的重组生产
|
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
US20050271660A1
(en)
|
2002-09-06 |
2005-12-08 |
Alexion Pharmaceuticals, Inc. |
Nebulization of monoclonal antibodies for treating pulmonary diseases
|
|
US20110223168A1
(en)
*
|
2002-12-27 |
2011-09-15 |
Greg Winter |
Ligand that has binding specificity for il-4 and/or il-13
|
|
GB0230201D0
(en)
*
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Retargeting
|
|
EP2395017A3
(en)
|
2003-05-30 |
2012-12-19 |
Merus B.V. |
Design and use of paired variable regions of specific binding molecules
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
WO2005068622A2
(en)
*
|
2004-01-20 |
2005-07-28 |
Merus B.V. |
Mixtures of binding proteins
|
|
EP1761561B1
(en)
*
|
2004-01-20 |
2015-08-26 |
KaloBios Pharmaceuticals, Inc. |
Antibody specificity transfer using minimal essential binding determinants
|
|
TW201705980A
(zh)
*
|
2004-04-09 |
2017-02-16 |
艾伯維生物技術有限責任公司 |
用於治療ＴＮＦα相關失調症之多重可變劑量療法
|
|
JP5017097B2
(ja)
*
|
2004-04-26 |
2012-09-05 |
セントカー・インコーポレーテツド |
設計デコイタンパク質を用いる溶液相バイオパニング方法
|
|
US7790405B2
(en)
|
2004-04-26 |
2010-09-07 |
Centocor, Inc. |
Solution phase biopanning method using engineered decoy proteins
|
|
US7514539B2
(en)
|
2004-04-26 |
2009-04-07 |
Centocor, Inc. |
Epitope directed selection of antibodies to murine tissue factor
|
|
TW200607523A
(en)
|
2004-06-01 |
2006-03-01 |
Domantis Ltd |
Drug compositions, fusions and conjugates
|
|
AU2006208286A1
(en)
|
2005-01-26 |
2006-08-03 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
KR100675791B1
(ko)
*
|
2005-02-04 |
2007-02-02 |
제주대학교 산학협력단 |
육상어류양식장용 자동먹이공급시스템
|
|
US8052974B2
(en)
|
2005-05-12 |
2011-11-08 |
Crucell Holland B.V. |
Host cell specific binding molecules capable of neutralizing viruses and uses thereof
|
|
WO2006136601A1
(en)
*
|
2005-06-23 |
2006-12-28 |
Crucell Holland B.V. |
Optimization of west nile virus antibodies
|
|
HUE026303T2
(hu)
|
2005-07-25 |
2016-06-28 |
Emergent Product Dev Seattle |
B-sejt csökkentés CD37-specifikus és CD20-specifikus kapcsoló molekulák alkalmazásával
|
|
EP2500358A3
(en)
|
2005-08-19 |
2012-10-17 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
NZ597168A
(en)
|
2005-08-19 |
2013-07-26 |
Abbott Lab |
Dual variable domain immunoglobin and uses thereof
|
|
WO2007039256A2
(de)
|
2005-09-30 |
2007-04-12 |
Abbott Gmbh & Co. Kg |
Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung
|
|
WO2007042524A2
(en)
*
|
2005-10-14 |
2007-04-19 |
Novo Nordisk A/S |
Treating diabetes using inhibitors of il-1
|
|
AU2007238677B2
(en)
*
|
2006-04-14 |
2011-03-10 |
Novartis Ag |
Use of IL-I antibodies for treating ophthalmic disorders
|
|
DK2027155T3
(en)
|
2006-06-06 |
2016-05-09 |
Crucell Holland Bv |
HUMAN BINDING MOLECULES with killer activity against staphylococci and uses thereof
|
|
MX2008015524A
(es)
|
2006-06-12 |
2009-01-13 |
Trubion Pharmaceuticals Inc |
Proteinas de union multivalentes monocatenarias con funcion efectora.
|
|
US20090017455A1
(en)
*
|
2006-08-02 |
2009-01-15 |
Kwong Gabriel A |
Methods and systems for detecting and/or sorting targets
|
|
EP2059533B1
(en)
|
2006-08-30 |
2012-11-14 |
Genentech, Inc. |
Multispecific antibodies
|
|
CN103405768A
(zh)
*
|
2006-12-20 |
2013-11-27 |
爱克索马技术有限公司 |
用于治疗IL-1β相关疾病的方法
|
|
WO2008082651A2
(en)
*
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Dual-specific il-1a/ il-1b antibodies
|
|
US8092998B2
(en)
|
2007-05-31 |
2012-01-10 |
Abbott Laboratories |
Biomarkers predictive of the responsiveness to TNFα inhibitors in autoimmune disorders
|
|
CA2700714C
(en)
|
2007-09-26 |
2018-09-11 |
Ucb Pharma S.A. |
Dual specificity antibody fusions
|
|
AU2008338421A1
(en)
|
2007-12-17 |
2009-06-25 |
Dyax Corp. |
Compositions and methods for treating osteolytic disorders comprising MMP-14 binding proteins
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
JP2011517320A
(ja)
*
|
2008-03-03 |
2011-06-02 |
ダイアックス コーポレーション |
メタロプロテアーゼ９結合タンパク質およびメタロプロテアーゼ２結合タンパク質
|
|
AU2009222048A1
(en)
|
2008-03-03 |
2009-09-11 |
Dyax Corp. |
Metalloproteinase 9 binding proteins
|
|
AU2009234277B2
(en)
|
2008-04-11 |
2014-12-04 |
Aptevo Research And Development Llc |
CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
|
BRPI0910482A2
(pt)
|
2008-04-29 |
2019-09-24 |
Abbott Lab |
imunoglobinas de domínio variável duplo e usos das mesmas
|
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
EP2297209A4
(en)
*
|
2008-06-03 |
2012-08-01 |
Abbott Lab |
IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF
|
|
AU2009256246B2
(en)
|
2008-06-03 |
2013-07-18 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
BRPI0915448A2
(pt)
*
|
2008-07-08 |
2015-11-10 |
Abbott Lab |
imunoglobulinas de domínio variável duplo para prostaglandina e2 e usos das mesmas
|
|
ES2628108T3
(es)
|
2008-09-03 |
2017-08-01 |
F. Hoffmann-La Roche Ag |
Anticuerpos multiespecíficos
|
|
JP2012502059A
(ja)
*
|
2008-09-05 |
2012-01-26 |
ゾーマ テクノロジー リミテッド |
ＩＬ−１β関連疾患を処置または予防するための方法
|
|
JP5976319B2
(ja)
*
|
2008-09-12 |
2016-08-23 |
エックスバイオテク, インコーポレイテッドXbiotech, Inc. |
病原性単球の標的化
|
|
CA2737241C
(en)
|
2008-09-26 |
2017-08-29 |
Ucb Pharma S.A. |
Multivalent antibody fusion proteins
|
|
EP2196476A1
(en)
|
2008-12-10 |
2010-06-16 |
Novartis Ag |
Antibody formulation
|
|
WO2010087972A2
(en)
*
|
2009-01-29 |
2010-08-05 |
Abbott Laboratories |
Il-1 binding proteins
|
|
PE20160651A1
(es)
|
2009-03-05 |
2016-07-24 |
Abbvie Inc |
Proteinas de union a il-17
|
|
PE20120591A1
(es)
*
|
2009-04-02 |
2012-05-23 |
Roche Glycart Ag |
Anticuerpos multiespecificos que comprenden anticuerpos de longitud completa y fragmentos fab de cadena sencilla
|
|
CN101957365B
(zh)
*
|
2009-07-21 |
2013-08-07 |
卫生部北京医院 |
检测抗环瓜氨酸肽和抗免疫球蛋白g双特异性抗体的试剂盒
|
|
UY32808A
(es)
*
|
2009-07-29 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas como dominio variable dual y usos de las mismas
|
|
CN102741288B
(zh)
|
2009-08-29 |
2015-08-19 |
Abbvie公司 |
治疗用dll4结合蛋白
|
|
JP2013503607A
(ja)
|
2009-09-01 |
2013-02-04 |
アボット・ラボラトリーズ |
二重可変ドメイン免疫グロブリンおよびその使用
|
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
|
MX2012004415A
(es)
|
2009-10-15 |
2012-05-08 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
|
IN2012DN02634A
(cg-RX-API-DMAC7.html)
*
|
2009-10-15 |
2015-09-04 |
Abbvie Inc |
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
EP2510001B1
(en)
|
2009-12-08 |
2015-12-02 |
AbbVie Deutschland GmbH & Co KG |
Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
|
|
EP2523974A4
(en)
*
|
2010-01-12 |
2013-11-06 |
Oncomed Pharm Inc |
WNT BINDING AGENTS AND USES THEREOF
|
|
KR101853278B1
(ko)
|
2010-03-02 |
2018-05-02 |
애브비 인코포레이티드 |
치료학적 ｄｌｌ４ 결합 단백질
|
|
CA2796633C
(en)
*
|
2010-04-23 |
2020-10-27 |
Genentech, Inc. |
Production of heteromultimeric proteins
|
|
UY33386A
(es)
|
2010-05-14 |
2011-12-30 |
Abbott Laboratoires |
Proteínas de unión a il-1
|
|
US20120009196A1
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
JP2013537415A
(ja)
|
2010-08-03 |
2013-10-03 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリンおよびその使用
|
|
MX2013001267A
(es)
*
|
2010-08-13 |
2013-04-10 |
Genentech Inc |
ANTICUERPOS A IL-1ß E EIL-18 PARA TRATAMIENTO DE ENFERMEDAD.
|
|
CN103260639A
(zh)
|
2010-08-26 |
2013-08-21 |
Abbvie公司 |
双重可变结构域免疫球蛋白及其用途
|
|
WO2012121775A2
(en)
|
2010-12-21 |
2012-09-13 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
|
BR112013020259A2
(pt)
*
|
2011-02-08 |
2018-05-15 |
Abbvie Inc |
tratamento de osteoartrite e dores
|
|
WO2012163521A1
(en)
|
2011-05-27 |
2012-12-06 |
Dutalys |
Removal of monomeric targets
|
|
FI2726510T3
(fi)
|
2011-05-27 |
2023-05-04 |
Hoffmann La Roche |
Kaksoiskohdennus
|
|
KR20140033152A
(ko)
|
2011-06-20 |
2014-03-17 |
교와 핫꼬 기린 가부시키가이샤 |
항erbB3 항체
|
|
WO2013059439A2
(en)
|
2011-10-21 |
2013-04-25 |
Dyax Corp. |
Combination therapy comprising an mmp-14 binding protein
|
|
US8999331B2
(en)
|
2011-10-24 |
2015-04-07 |
Abbvie Inc. |
Immunobinders directed against sclerostin
|
|
HK1200321A1
(en)
|
2011-10-24 |
2015-08-07 |
Abbvie Inc. |
Bispecific immunobinders directed against tnf and il-17
|
|
KR20140097430A
(ko)
*
|
2011-11-21 |
2014-08-06 |
애브비 인코포레이티드 |
Ｉｌ-1 결합 단백질
|
|
RU2482181C1
(ru)
*
|
2011-12-07 |
2013-05-20 |
Учреждение Российской академии медицинских наук Российский онкологический научный центр имени Н.Н. Блохина РАМН |
Клеточная линия d11 множественной миеломы человека, используемая для гибридомной технологии
|
|
AU2012352168C1
(en)
|
2011-12-14 |
2018-01-25 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
|
CN104136462B
(zh)
|
2011-12-14 |
2017-06-09 |
艾伯维德国有限责任两合公司 |
用于诊断和治疗铁相关病症的组合物和方法
|
|
KR101963230B1
(ko)
|
2011-12-26 |
2019-03-29 |
삼성전자주식회사 |
복수개의 단일 항체를 포함하는 단백질 복합체
|
|
UY34558A
(es)
|
2011-12-30 |
2013-07-31 |
Abbvie Inc |
Proteínas de unión específicas duales dirigidas contra il-13 y/o il-17
|
|
TW201333033A
(zh)
|
2011-12-30 |
2013-08-16 |
Abbvie Inc |
雙可變域免疫球蛋白及其用途
|
|
EP3369746A1
(en)
|
2012-01-27 |
2018-09-05 |
AbbVie Deutschland GmbH & Co KG |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
|
GB2502127A
(en)
|
2012-05-17 |
2013-11-20 |
Kymab Ltd |
Multivalent antibodies and in vivo methods for their production
|
|
MX360110B
(es)
|
2012-04-20 |
2018-10-23 |
Merus Nv |
Metodos y medios para la produccion de moleculas de tipo ig.
|
|
AR091755A1
(es)
|
2012-07-12 |
2015-02-25 |
Abbvie Inc |
Proteinas de union a il-1
|
|
KR101911438B1
(ko)
|
2012-10-31 |
2018-10-24 |
삼성전자주식회사 |
이중 특이 항원 결합 단백질 복합체 및 이중 특이 항체의 제조 방법
|
|
KR20210111353A
(ko)
|
2012-11-01 |
2021-09-10 |
애브비 인코포레이티드 |
항-ｖｅｇｆ／ｄｌｌ4 이원 가변 도메인 면역글로불린 및 이의 용도
|
|
CN105431453A
(zh)
*
|
2012-11-01 |
2016-03-23 |
艾伯维公司 |
稳定的双重可变结构域免疫球蛋白制剂
|
|
BR112015012014A2
(pt)
|
2012-12-04 |
2017-07-11 |
Abbvie Inc |
proteínas de ligação específicas duais penetrando a barreira hematoencefálica (bbb)
|
|
US9856319B2
(en)
|
2012-12-28 |
2018-01-02 |
Abbvie Inc. |
Monovalent binding proteins
|
|
EP2938634A2
(en)
*
|
2012-12-28 |
2015-11-04 |
AbbVie Inc. |
Dual specific binding proteins having a receptor sequence
|
|
JP2016510319A
(ja)
|
2012-12-28 |
2016-04-07 |
アッヴィ・インコーポレイテッド |
多価結合タンパク質組成物
|
|
WO2014116846A2
(en)
|
2013-01-23 |
2014-07-31 |
Abbvie, Inc. |
Methods and compositions for modulating an immune response
|
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
|
TW201446800A
(zh)
|
2013-03-15 |
2014-12-16 |
Abbvie Inc |
針對ＴＮＦα之雙特異性結合蛋白
|
|
AU2014227732A1
(en)
|
2013-03-15 |
2015-09-17 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-1 beta and IL-17
|
|
JP6581572B2
(ja)
|
2013-06-07 |
2019-09-25 |
デューク ユニバーシティ |
補体因子ｈ阻害薬
|
|
CN103308697B
(zh)
*
|
2013-06-09 |
2014-11-26 |
卫生部北京医院 |
检测抗丙型肝炎病毒编码的非结构蛋白ns3和ns5的天然双特异性抗体的试剂盒
|
|
US9879081B2
(en)
|
2013-06-25 |
2018-01-30 |
Samsung Electronics Co., Ltd. |
Protein complex, bispecific antibody including the protein complex, and method of preparation thereof
|
|
US20160271230A1
(en)
|
2013-09-17 |
2016-09-22 |
University Health Network (Uhn): Technology Development And Commercialization |
Agents directed against a cis rgma/neogenin interaction or lipid rafts and use of the same in methods of treatment
|
|
CA2922950A1
(en)
*
|
2013-09-30 |
2015-04-02 |
Shinya Ishii |
Method for producing antigen-binding molecule using modified helper phage
|
|
MX380937B
(es)
*
|
2013-12-20 |
2025-03-12 |
Genentech Inc |
Anticuerpos dobles especificos.
|
|
CA2943707A1
(en)
|
2014-05-06 |
2015-11-12 |
Genentech, Inc. |
Production of heteromultimeric proteins using mammalian cells
|
|
US20160000936A1
(en)
|
2014-06-10 |
2016-01-07 |
Abbvie Inc. |
Biomarkers for inflammatory disease and methods of using same
|
|
US20160002343A1
(en)
|
2014-06-11 |
2016-01-07 |
Abbvie Inc. |
Blood-brain barrier (bbb) penetrating dual specific binding proteins for treating brain and neurological diseases
|
|
EP2985294A1
(en)
|
2014-08-14 |
2016-02-17 |
Deutsches Krebsforschungszentrum |
Recombinant antibody molecule and its use for target cell restricted T cell activation
|
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
|
JP6655302B2
(ja)
*
|
2015-05-29 |
2020-02-26 |
デンカ生研株式会社 |
被検対象の検出方法並びにそのための免疫測定器具及びモノクローナル抗体
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
EP3347378A1
(en)
|
2015-09-11 |
2018-07-18 |
AbbVie Inc. |
Methods for treating relapsing forms of multiple sclerosis
|
|
BR112018005573A2
(pt)
|
2015-09-21 |
2019-01-22 |
Aptevo Research And Development Llc |
?polipeptídeos de ligação a cd3?
|
|
EP3954709A1
(en)
|
2015-10-02 |
2022-02-16 |
F. Hoffmann-La Roche AG |
Bispecific antibodies specific for pd1 and tim3
|
|
WO2017055399A1
(en)
*
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Cellular based fret assay for the determination of simultaneous binding
|
|
CN109068658A
(zh)
|
2015-11-18 |
2018-12-21 |
杜克大学 |
用于治疗癌症的肿瘤浸润淋巴细胞
|
|
DK3365368T3
(da)
|
2016-03-11 |
2023-06-26 |
Scholar Rock Inc |
Tgfbeta1-bindende immunoglobuliner og anvendelse deraf
|
|
TW202523689A
(zh)
|
2016-06-01 |
2025-06-16 |
美商艾伯維有限公司 |
治療脊髓損傷及疼痛之方法
|
|
WO2018058111A1
(en)
|
2016-09-26 |
2018-03-29 |
The Brigham And Women's Hospital, Inc. |
Regulators of b cell-mediated immunosuppression
|
|
ES3001985T3
(en)
|
2016-10-03 |
2025-03-06 |
Abbott Lab |
Improved methods of assessing uch-l1 in patient samples
|
|
CN117398457A
(zh)
|
2017-01-06 |
2024-01-16 |
供石公司 |
亚型特异性、背景许可性TGFβ1抑制剂及其用途
|
|
US11016092B2
(en)
|
2017-03-23 |
2021-05-25 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase L1
|
|
UA125700C2
(uk)
|
2017-04-03 |
2022-05-18 |
Ф. Хоффманн-Ля Рош Аг |
Імунокон'югати антитіла до pd-1 з мутантом il-2
|
|
MA49038B1
(fr)
|
2017-04-05 |
2025-01-31 |
F. Hoffmann-La Roche Ag |
Anticorps bispécifiques se liant particulièrement à pd1 et lag3
|
|
BR112019021612A2
(pt)
|
2017-04-15 |
2020-05-12 |
Abbott Laboratories |
Métodos para auxiliar o diagnóstico hiperagudo e determinação de traumatismo crânioencefálico em um indivíduo humano com o uso de biomarcadores precoces
|
|
EP3635407B1
(en)
|
2017-04-28 |
2025-09-10 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
|
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
|
US10866251B2
(en)
|
2017-05-25 |
2020-12-15 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
|
CN110709704B
(zh)
|
2017-05-30 |
2024-06-21 |
雅培实验室 |
利用心肌肌钙蛋白i辅助诊断和评估人类受试者的轻度创伤性脑损伤的方法
|
|
CA3068041C
(en)
|
2017-07-03 |
2024-06-25 |
Abbott Laboratories |
Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood
|
|
GB201711208D0
(en)
|
2017-07-12 |
2017-08-23 |
Iontas Ltd |
Ion channel inhibitors
|
|
CA3081854A1
(en)
|
2017-11-08 |
2019-05-16 |
Kyowa Kirin Co., Ltd. |
Bispecific antibody which binds to cd40 and epcam
|
|
CA3067057A1
(en)
|
2017-12-09 |
2019-06-13 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
|
|
US11016105B2
(en)
|
2017-12-09 |
2021-05-25 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of GFAP and UCH-L1
|
|
EP3732489B1
(en)
|
2017-12-29 |
2025-10-22 |
Abbott Laboratories |
Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury
|
|
RS62914B1
(sr)
|
2018-07-11 |
2022-03-31 |
Scholar Rock Inc |
Izoform selektivni inhibitori tgfbeta1 i njihova upotreba
|
|
US20210340238A1
(en)
|
2018-07-11 |
2021-11-04 |
Scholar Rock, Inc. |
TGFß1 INHIBITORS AND USE THEREOF
|
|
MA53125A
(fr)
|
2018-07-11 |
2021-05-19 |
Scholar Rock Inc |
Inhibiteurs de tgf?1 sélectifs selon l'isoforme à affinité élevée
|
|
TWI873112B
(zh)
|
2018-12-28 |
2025-02-21 |
日商協和麒麟股份有限公司 |
與TfR結合之雙專一性抗體
|
|
WO2020180695A1
(en)
|
2019-03-01 |
2020-09-10 |
Abbott Laboratories |
Methods for predicting major adverse cardiovascular events in subjects with coronary artery disease
|
|
JP7502281B2
(ja)
|
2019-05-15 |
2024-06-18 |
協和キリン株式会社 |
Ｃｄ４０とｇｐｃ３に結合するバイスペシフィック抗体
|
|
WO2020230899A1
(ja)
|
2019-05-15 |
2020-11-19 |
協和キリン株式会社 |
Ｃｄ４０とｆａｐに結合するバイスペシフィック抗体
|
|
CA3166328A1
(en)
|
2020-01-11 |
2021-07-15 |
Scholar Rock, Inc. |
Tgf-beta inhibitors and use thereof
|
|
CN115190812A
(zh)
|
2020-01-11 |
2022-10-14 |
供石公司 |
TGFβ抑制剂及其用途
|
|
EP4136459A1
(en)
|
2020-04-13 |
2023-02-22 |
Abbott Laboratories |
Methods, complexes and kits for detecting or determining an amount of a ss-coronavirus antibody in a sample
|
|
CN111793131A
(zh)
*
|
2020-05-11 |
2020-10-20 |
廊坊天光生物技术有限公司 |
一种用于检测血清中pf4含量的抗体对及其用途
|
|
EP4149548A4
(en)
|
2020-05-13 |
2024-05-08 |
Disc Medicine, Inc. |
ANTI-HEMOJUVELIN ANTIBODIES (HJV) FOR THE TREATMENT OF MYELOFIBROSIS
|
|
EP4193149A1
(en)
|
2020-08-04 |
2023-06-14 |
Abbott Laboratories |
Improved methods and kits for detecting sars-cov-2 protein in a sample
|
|
CA3198161A1
(en)
|
2020-12-01 |
2022-06-09 |
Beth MCQUISTON |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
EP4271998A1
(en)
|
2020-12-30 |
2023-11-08 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
|
WO2022204581A2
(en)
|
2021-03-26 |
2022-09-29 |
Scholar Rock, Inc. |
Tgf-beta inhibitors and use thereof
|
|
BR112023024169A2
(pt)
|
2021-05-18 |
2024-02-06 |
Abbott Lab |
Métodos para avaliar lesão cerebral em um indivíduo pediátrico
|
|
WO2022256723A2
(en)
|
2021-06-03 |
2022-12-08 |
Scholar Rock, Inc. |
Tgf-beta inhibitors and therapeutic use thereof
|
|
CA3222291A1
(en)
|
2021-06-14 |
2022-12-22 |
Jaime MARINO |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
|
US20240301073A1
(en)
|
2021-07-14 |
2024-09-12 |
Scholar Rock, Inc. |
LTBP COMPLEX-SPECIFIC INHIBITORS OF TGFb1 AND USES THEREOF
|
|
JP2024530527A
(ja)
*
|
2021-08-13 |
2024-08-21 |
アブウィズ バイオ，インコーポレイテッド |
タンパク質及び抗体のヒト化、親和性成熟、及び最適化のための方法
|
|
CN118715440A
(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
|
AU2022339759A1
(en)
|
2021-08-31 |
2024-03-07 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
AU2022354059A1
(en)
|
2021-09-30 |
2024-03-28 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
EP4448179A1
(en)
|
2021-12-17 |
2024-10-23 |
Abbott Laboratories |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
|
WO2023150652A1
(en)
|
2022-02-04 |
2023-08-10 |
Abbott Laboratories |
Lateral flow methods, assays, and devices for detecting the presence or measuring the amount of ubiquitin carboxy-terminal hydrolase l1 and/or glial fibrillary acidic protein in a sample
|
|
EP4548100A1
(en)
|
2022-06-29 |
2025-05-07 |
Abbott Laboratories |
Magnetic point-of-care systems and assays for determining gfap in biological samples
|
|
WO2024059708A1
(en)
|
2022-09-15 |
2024-03-21 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
|
WO2024187051A1
(en)
|
2023-03-07 |
2024-09-12 |
Scholar Rock, Inc. |
Tgf-beta inhibitors for use for treating resistant or unresponsive cancer in patients
|
|
WO2024211475A1
(en)
|
2023-04-04 |
2024-10-10 |
Abbott Laboratories |
Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
|
|
WO2024226971A1
(en)
|
2023-04-28 |
2024-10-31 |
Abbott Point Of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|
|
WO2025108551A1
(en)
|
2023-11-23 |
2025-05-30 |
Mabylon Ag |
Multispecific anti-allergen antibodies and uses thereof
|
|
WO2025109206A1
(en)
|
2023-11-22 |
2025-05-30 |
Mabylon Ag |
Multispecific anti-allergen antibodies and uses thereof
|
|
WO2025230857A1
(en)
|
2024-05-01 |
2025-11-06 |
Abbott Laboratories |
Improved methods for determining cardiac myosin binding protein c in biological samples
|