JP2011522817A5 - - Google Patents
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- JP2011522817A5 JP2011522817A5 JP2011512418A JP2011512418A JP2011522817A5 JP 2011522817 A5 JP2011522817 A5 JP 2011522817A5 JP 2011512418 A JP2011512418 A JP 2011512418A JP 2011512418 A JP2011512418 A JP 2011512418A JP 2011522817 A5 JP2011522817 A5 JP 2011522817A5
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- Japan
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- 108010001336 Horseradish Peroxidase Proteins 0.000 claims description 86
- 239000000017 hydrogel Substances 0.000 claims description 44
- 229920000642 polymer Polymers 0.000 claims description 43
- DZGWFCGJZKJUFP-UHFFFAOYSA-N Tyramine Chemical compound NCCC1=CC=C(O)C=C1 DZGWFCGJZKJUFP-UHFFFAOYSA-N 0.000 claims description 22
- MHAJPDPJQMAIIY-UHFFFAOYSA-N hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 18
- 238000001879 gelation Methods 0.000 claims description 15
- 238000005259 measurement Methods 0.000 claims description 13
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 11
- 229960003732 tyramine Drugs 0.000 claims description 11
- 229920002674 hyaluronan Polymers 0.000 claims description 8
- 229960003160 hyaluronic acid Drugs 0.000 claims description 8
- MAKUBRYLFHZREJ-JWBQXVCJSA-M sodium;(2S,3S,4R,5R,6R)-3-[(2S,3R,5S,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylate Chemical compound [Na+].CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C([O-])=O)O[C@@H](O)[C@H](O)[C@H]1O MAKUBRYLFHZREJ-JWBQXVCJSA-M 0.000 claims description 8
- 239000000499 gel Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 238000004132 cross linking Methods 0.000 claims description 2
- 239000000243 solution Substances 0.000 description 87
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drugs Drugs 0.000 description 2
- 239000002953 phosphate buffered saline Substances 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000005755 formation reaction Methods 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/SG2008/000204 WO2009148405A1 (fr) | 2008-06-05 | 2008-06-05 | Formation d'hydrogel en présence de peroxydase et d'une faible concentration de peroxyde d'hydrogène |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011522817A JP2011522817A (ja) | 2011-08-04 |
| JP2011522817A5 true JP2011522817A5 (fr) | 2012-07-12 |
| JP5563563B2 JP5563563B2 (ja) | 2014-07-30 |
Family
ID=41398337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011512418A Expired - Fee Related JP5563563B2 (ja) | 2008-06-05 | 2008-06-05 | ペルオキシダーゼおよび低濃度の過酸化水素の存在下でのヒドロゲルの形成方法 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP5563563B2 (fr) |
| WO (1) | WO2009148405A1 (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5843758B2 (ja) | 2009-05-29 | 2016-01-13 | エージェンシー フォー サイエンス， テクノロジー アンド リサーチ | フラボノイドハイドロゲル |
| KR101091028B1 (ko) * | 2009-07-02 | 2011-12-09 | 아주대학교산학협력단 | 체내 주입형 하이드로젤 및 이의 생의학적 용도 |
| KR101103423B1 (ko) * | 2009-09-04 | 2012-01-06 | 아주대학교산학협력단 | 생체 주입형 조직 접착성 하이드로젤 및 이의 생의학적 용도 |
| CZ302503B6 (cs) | 2009-12-11 | 2011-06-22 | Contipro C A.S. | Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace |
| CZ2009836A3 (cs) | 2009-12-11 | 2011-06-22 | Contipro C A.S. | Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace |
| CN101864178A (zh) * | 2010-06-17 | 2010-10-20 | 复旦大学 | 一种可注射的化学交联蛋白质/多肽水凝胶及其制备方法 |
| CZ2012136A3 (cs) * | 2012-02-28 | 2013-06-05 | Contipro Biotech S.R.O. | Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití |
| CZ304512B6 (cs) | 2012-08-08 | 2014-06-11 | Contipro Biotech S.R.O. | Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití |
| CZ2012842A3 (cs) | 2012-11-27 | 2014-08-20 | Contipro Biotech S.R.O. | Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití |
| US10052389B2 (en) * | 2013-02-13 | 2018-08-21 | Agency For Science, Technology And Research | Polymeric system for release of an active agent |
| WO2014204406A1 (fr) * | 2013-06-18 | 2014-12-24 | Agency For Science, Technology And Research | Procédé de culture de cellules souches cancéreuses |
| GB2518405A (en) * | 2013-09-20 | 2015-03-25 | Zeiss Carl Meditec Ag | Composition comprising at least one viscoelastic polymer |
| CZ305153B6 (cs) | 2014-03-11 | 2015-05-20 | Contipro Biotech S.R.O. | Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití |
| CN104004231A (zh) * | 2014-06-12 | 2014-08-27 | 东南大学 | 一种生物大分子互穿网络水凝胶及其制备方法 |
| CZ2014451A3 (cs) | 2014-06-30 | 2016-01-13 | Contipro Pharma A.S. | Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití |
| CZ309295B6 (cs) | 2015-03-09 | 2022-08-10 | Contipro A.S. | Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití |
| CZ306479B6 (cs) | 2015-06-15 | 2017-02-08 | Contipro A.S. | Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin |
| CZ306662B6 (cs) | 2015-06-26 | 2017-04-26 | Contipro A.S. | Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití |
| AU2016353345B2 (en) | 2015-11-12 | 2021-12-23 | University Of Virginia Patent Foundation | Compositions and methods for vas-occlusive contraception and reversal thereof |
| CA3021092A1 (fr) * | 2016-05-12 | 2017-11-16 | Insitu Biologics, Llc | Vehicule d'administration biologique a base d'hydrogel comprenant des biopolymeres avec des substitutions de tyramine |
| CZ308106B6 (cs) | 2016-06-27 | 2020-01-08 | Contipro A.S. | Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití |
| JP6834545B2 (ja) * | 2017-02-01 | 2021-02-24 | Jsr株式会社 | 変性多糖およびその用途 |
| JP6939607B2 (ja) * | 2017-03-27 | 2021-09-22 | Jsr株式会社 | 組成物およびその用途 |
| CN107312193A (zh) * | 2017-06-27 | 2017-11-03 | 吉林大学 | 一种仿生的可注射黏附性水凝胶、制备方法及其在生物方面的应用 |
| CN108478852A (zh) * | 2018-04-08 | 2018-09-04 | 湖北工程学院 | 一种药学制品、用于负载医药制品的载体、水凝胶及其方法 |
| EP3880273A4 (fr) | 2018-11-13 | 2022-08-24 | Contraline, Inc. | Systèmes et méthodes d'administration de biomatériaux |
| CZ2019360A3 (cs) * | 2019-06-10 | 2020-12-23 | Contipro A.S. | Sada pro přípravu hydrogelu na bázi hydroxyfenylového derivátu hyaluronanu, způsob přípravy hydrogelu a jeho použití |
| WO2021035217A1 (fr) * | 2019-08-22 | 2021-02-25 | Contraline, Inc. | Compositions et méthode de libération prolongée de médicaments contenus dans un hydrogel injectable |
| WO2021077116A1 (fr) * | 2019-10-18 | 2021-04-22 | Trustees Of Tufts College | Modification chimique de fibroïne de soie pour la fabrication d'hydrogels réticulés par voie enzymatique ayant une cinétique de gélification et une bioactivité ajustables |
| CZ2020263A3 (cs) * | 2020-05-12 | 2021-10-27 | Contipro A.S. | Sada gelotvorných roztoků určená pro přípravu hydrogelu na bázi kovalentně zesítěného hydroxyfenylového derivátu hyaluronanu k prevenci pooperačních komplikací souvisejících s vytvořením kolorektální anastomózy a její použití |
| AU2021273196A1 (en) * | 2020-05-14 | 2022-12-15 | Contraline, Inc. | Biomaterial compositions and methods of delivery |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7465766B2 (en) * | 2004-01-08 | 2008-12-16 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| EP1888651B1 (fr) * | 2005-05-20 | 2014-07-30 | Agency for Science, Technology and Research | Preparations de flavonoides conjugues a des aldehydes |
| US20090186077A1 (en) * | 2006-02-15 | 2009-07-23 | Ying Jackie Y | Thermo-responsive materials |
| CN101405037A (zh) * | 2006-02-27 | 2009-04-08 | 新加坡科技研究局 | 可固化骨粘固剂 |
-
2008
- 2008-06-05 WO PCT/SG2008/000204 patent/WO2009148405A1/fr active Application Filing
- 2008-06-05 JP JP2011512418A patent/JP5563563B2/ja not_active Expired - Fee Related
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