JP2011519292A5 - - Google Patents

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Publication number
JP2011519292A5
JP2011519292A5 JP2011504554A JP2011504554A JP2011519292A5 JP 2011519292 A5 JP2011519292 A5 JP 2011519292A5 JP 2011504554 A JP2011504554 A JP 2011504554A JP 2011504554 A JP2011504554 A JP 2011504554A JP 2011519292 A5 JP2011519292 A5 JP 2011519292A5
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JP
Japan
Prior art keywords
functional group
group
cation
acid
polysaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011504554A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011519292A (ja
Filing date
Publication date
Priority claimed from FR0854621A external-priority patent/FR2933306B1/fr
Priority claimed from FR0857560A external-priority patent/FR2937863B1/fr
Application filed filed Critical
Priority claimed from PCT/IB2009/005235 external-priority patent/WO2009127940A1/fr
Publication of JP2011519292A publication Critical patent/JP2011519292A/ja
Publication of JP2011519292A5 publication Critical patent/JP2011519292A5/ja
Pending legal-status Critical Current

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JP2011504554A 2008-04-14 2009-04-14 成長因子/両親媒性ポリマー複合体、可溶性のカチオン塩及び有機支持体を含有する骨形成組成物 Pending JP2011519292A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US7113108P 2008-04-14 2008-04-14
US61/071,131 2008-04-14
US12901208P 2008-05-30 2008-05-30
US61/129,012 2008-05-30
FR0854621A FR2933306B1 (fr) 2008-07-07 2008-07-07 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et une matrice organique
FR0854621 2008-07-07
US12961608P 2008-07-08 2008-07-08
US61/129,616 2008-07-08
US19321608P 2008-11-06 2008-11-06
FR0857560 2008-11-06
FR0857560A FR2937863B1 (fr) 2008-11-06 2008-11-06 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et un gel
US61/193,216 2008-11-06
PCT/IB2009/005235 WO2009127940A1 (fr) 2008-04-14 2009-04-14 Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation e un support organique

Publications (2)

Publication Number Publication Date
JP2011519292A JP2011519292A (ja) 2011-07-07
JP2011519292A5 true JP2011519292A5 (https=) 2012-06-07

Family

ID=40791051

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011504554A Pending JP2011519292A (ja) 2008-04-14 2009-04-14 成長因子/両親媒性ポリマー複合体、可溶性のカチオン塩及び有機支持体を含有する骨形成組成物

Country Status (12)

Country Link
US (2) US20090291114A1 (https=)
EP (1) EP2288370A1 (https=)
JP (1) JP2011519292A (https=)
KR (1) KR20110014588A (https=)
CN (1) CN102065882A (https=)
AU (1) AU2009237414A1 (https=)
BR (1) BRPI0906553A2 (https=)
CA (1) CA2720203A1 (https=)
IL (1) IL208139A0 (https=)
MX (1) MX2010011267A (https=)
WO (1) WO2009127940A1 (https=)
ZA (1) ZA201006627B (https=)

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FR2948573B1 (fr) * 2009-07-31 2011-11-18 Adocia Nouvelle forme d'administration de complexes de proteines osteogeniques
FR2943538B1 (fr) 2009-03-27 2011-05-20 Adocia Formulation a action rapide d'insuline recombinante humaine
FR2975099A1 (fr) * 2011-05-10 2012-11-16 Adocia Polysaccharides a degre de fonctionnalisation modulable
US9018190B2 (en) 2009-03-27 2015-04-28 Adocia Functionalized oligosaccharides
FR2980796B1 (fr) * 2011-09-30 2014-07-04 Adocia Oligosaccharides fonctionnalises
FR2952375A1 (fr) * 2009-11-10 2011-05-13 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par esterification par un derive d'alcool hydrophobe
FR2956116A1 (fr) * 2010-02-09 2011-08-12 Adocia Complexes polysaccharide/bmp-7 solubles a ph physiologique
FR2958646B1 (fr) 2010-04-07 2012-05-18 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par un derive d'acide hydrophobe.
FR2958647B1 (fr) * 2010-04-08 2013-08-23 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par un derive hydrophobe porte par un spacer au moins trivalent.
BR112012019580A2 (pt) * 2010-02-09 2020-08-18 Adocia "polissacarídeos antônicos funcionalizados por pelo menos dois grupos hidrofóbicos carreados por pelo menos um espaçador trivalente
EP2828297A1 (fr) * 2011-05-10 2015-01-28 Adocia Oligosaccharides fonctionnalisés
US20120295833A1 (en) * 2011-05-10 2012-11-22 Adocia Polysaccharides having an adjustable degree of functionalization
FR2984749A1 (fr) * 2011-12-23 2013-06-28 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 en combinaison avec une hormone gastro-intestinale a visee therapeutique
US20130231281A1 (en) 2011-11-02 2013-09-05 Adocia Rapid acting insulin formulation comprising an oligosaccharide
KR102000041B1 (ko) 2011-12-29 2019-07-16 엘지디스플레이 주식회사 발광표시장치 및 그 구동방법
KR101364704B1 (ko) * 2012-06-12 2014-02-20 순천향대학교 산학협력단 골 재생을 위한 다공성 하이드로젤 지지체의 제조방법
CN104902922B (zh) 2012-11-13 2017-12-12 阿道恰公司 包含经取代阴离子化合物的速效胰岛素制剂
US8945872B2 (en) 2013-01-25 2015-02-03 Warsaw Orthopedic, Inc. Methods of purifying human recombinant growth and differentiation factor-5 (rhGDF-5) protein
US8956829B2 (en) 2013-01-25 2015-02-17 Warsaw Orthopedic, Inc. Human recombinant growth and differentiaton factor-5 (rhGDF-5)
US9359417B2 (en) 2013-01-25 2016-06-07 Warsaw Orthopedic, Inc. Cell cultures and methods of human recombinant growth and differentiaton factor-5 (rhGDF-5)
US9169308B2 (en) 2013-01-25 2015-10-27 Warsaw Orthopedic, Inc. Methods and compositions of human recombinant growth and differentiation factor-5 (rhGDF-5) isolated from inclusion bodies
US9051389B2 (en) 2013-01-25 2015-06-09 Warsaw Orthopedic, Inc. Expression conditions and methods of human recombinant growth and differentiation factor-5 (rhGDF-5)
KR101429857B1 (ko) * 2013-06-19 2014-08-13 순천향대학교 산학협력단 골 지혈작용을 위한 복합이중층 섬유매트의 제조방법
ES2806026T3 (es) * 2013-12-24 2021-02-16 Ares Trading Sa Formulación de FGF-18 en hidrogeles de alginato/colágeno
FR3020947B1 (fr) 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
WO2016127253A1 (en) * 2015-02-09 2016-08-18 Spatafora Michael Method and system for enhancing the activity of bone morphogenetic proteins
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
CN108690205A (zh) * 2018-05-28 2018-10-23 深圳市第二人民医院 一种ⅱ型胶原和聚丙烯酰胺复合水凝胶及其制备和应用
CN110368519B (zh) * 2019-08-26 2021-09-21 浙江瑞谷生物科技有限公司 一种基于贻贝粘蛋白的骨科粘合剂
US12343426B2 (en) 2021-04-06 2025-07-01 Boston Scientific Scimed, Inc. Therapeutic hydrogels
CN113563493B (zh) * 2021-07-01 2022-06-24 蚌埠医学院 疏水化多糖及其制备方法与应用
CN113662961B (zh) * 2021-07-19 2023-05-12 上海市第十人民医院 一种可捕获镁离子的微流控水凝胶微球及制备方法与应用
CN117757705B (zh) * 2023-04-28 2024-12-20 元素驱动(杭州)生物科技有限公司 可实现支链氨基酸联产的基因工程菌株的构建及其应用

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FR2781485B1 (fr) * 1998-07-21 2003-08-08 Denis Barritault Polymeres biocompatibles leur procede de preparation et les compositions les contenant
JP4548623B2 (ja) * 1999-02-24 2010-09-22 多木化学株式会社 生体材料
JP2002539172A (ja) * 1999-03-17 2002-11-19 ノバルティス アクチエンゲゼルシャフト Tgf−ベータを含む医薬組成物
CA2372994C (en) * 1999-06-04 2010-03-23 Alza Corporation Implantable gel compositions and method of manufacture
FR2794649B1 (fr) * 1999-06-11 2003-04-11 Solutions Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
US7033603B2 (en) * 1999-08-06 2006-04-25 Board Of Regents The University Of Texas Drug releasing biodegradable fiber for delivery of therapeutics
US20050244393A1 (en) * 1999-12-22 2005-11-03 Henogen S.A. Sealant or tissue generating product
TWI282283B (en) * 2002-05-17 2007-06-11 Wyeth Corp Injectable solid hyaluronic acid carriers for delivery of osteogenic proteins
FR2840614B1 (fr) * 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
US8895540B2 (en) * 2003-11-26 2014-11-25 DePuy Synthes Products, LLC Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
US7544661B2 (en) * 2003-12-05 2009-06-09 Northwestern University Self-assembling peptide amphiphiles and related methods for growth factor delivery
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JP2007037378A (ja) * 2005-07-29 2007-02-08 Pioneer Electronic Corp スイッチング電源の停電検出回路
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FR2891149B1 (fr) * 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
US20070178159A1 (en) * 2006-01-30 2007-08-02 Alza Corporation In-Situ Forming Porous Scaffold
US20070184087A1 (en) * 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
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US20080147197A1 (en) * 2006-12-14 2008-06-19 Mckay William F Biodegradable osteogenic porous biomedical implant with impermeable membrane
FR2919188B1 (fr) * 2007-07-27 2010-02-26 Proteins & Peptides Man Complexes entre un polymere amphiphile et une proteine osteogenique appartenant a la famille des bmps

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