FR2937863B1 - Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et un gel - Google Patents

Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et un gel

Info

Publication number
FR2937863B1
FR2937863B1 FR0857560A FR0857560A FR2937863B1 FR 2937863 B1 FR2937863 B1 FR 2937863B1 FR 0857560 A FR0857560 A FR 0857560A FR 0857560 A FR0857560 A FR 0857560A FR 2937863 B1 FR2937863 B1 FR 2937863B1
Authority
FR
France
Prior art keywords
gel
growth factor
cation salt
anionic polysaccharide
soluble cation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0857560A
Other languages
English (en)
Other versions
FR2937863A1 (fr
Inventor
Olivier Soula
Remi Soula
Gerard Soula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adocia SAS
Original Assignee
Adocia SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0857560A priority Critical patent/FR2937863B1/fr
Application filed by Adocia SAS filed Critical Adocia SAS
Priority to CA2720203A priority patent/CA2720203A1/fr
Priority to BRPI0906553-9A priority patent/BRPI0906553A2/pt
Priority to RU2010146243/15A priority patent/RU2010146243A/ru
Priority to PCT/IB2009/005235 priority patent/WO2009127940A1/fr
Priority to MX2010011267A priority patent/MX2010011267A/es
Priority to CN2009801132626A priority patent/CN102065882A/zh
Priority to US12/385,605 priority patent/US20090291114A1/en
Priority to JP2011504554A priority patent/JP2011519292A/ja
Priority to AU2009237414A priority patent/AU2009237414A1/en
Priority to EP09732932A priority patent/EP2288370A1/fr
Priority to KR1020107025338A priority patent/KR20110014588A/ko
Publication of FR2937863A1 publication Critical patent/FR2937863A1/fr
Priority to IL208139A priority patent/IL208139A0/en
Priority to ZA2010/06627A priority patent/ZA201006627B/en
Priority to US13/064,092 priority patent/US20110159068A1/en
Application granted granted Critical
Publication of FR2937863B1 publication Critical patent/FR2937863B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
FR0857560A 2008-04-14 2008-11-06 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et un gel Expired - Fee Related FR2937863B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR0857560A FR2937863B1 (fr) 2008-11-06 2008-11-06 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et un gel
EP09732932A EP2288370A1 (fr) 2008-04-14 2009-04-14 Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation e un support organique
RU2010146243/15A RU2010146243A (ru) 2008-04-14 2009-04-14 Остеогенная композиция, содержащая комплекс фактор роста/амфифильный полимер, растворимую соль катиона и органический носитель
PCT/IB2009/005235 WO2009127940A1 (fr) 2008-04-14 2009-04-14 Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation e un support organique
MX2010011267A MX2010011267A (es) 2008-04-14 2009-04-14 Composicion osteogenica que comprende un complejo del factor de crecimiento/polimero anfifilico, una sal de cation soluble y un soporte organico.
CN2009801132626A CN102065882A (zh) 2008-04-14 2009-04-14 包含生长因子/两亲性聚合物复合物、阳离子的可溶性盐和有机支持物的成骨组合物
US12/385,605 US20090291114A1 (en) 2008-04-14 2009-04-14 Osteogenic composition comprising a growth factor/amphiphilic polymer complex, a soluble cation salt and an organic support
JP2011504554A JP2011519292A (ja) 2008-04-14 2009-04-14 成長因子／両親媒性ポリマー複合体、可溶性のカチオン塩及び有機支持体を含有する骨形成組成物
CA2720203A CA2720203A1 (fr) 2008-04-14 2009-04-14 Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation et un support organique
BRPI0906553-9A BRPI0906553A2 (pt) 2008-04-14 2009-04-14 ''implante aberto constituído por uma composição osteogênica e método de preparação do implante''
KR1020107025338A KR20110014588A (ko) 2008-04-14 2009-04-14 성장인자/양친매성 중합체 복합체, 가용성 양이온 염 및 유기 지지체를 포함하는 골형성 조성물
AU2009237414A AU2009237414A1 (en) 2008-04-14 2009-04-14 Osteogenic composition including a complex growth factor/amphiphilic polymer, a soluble cation salt, and an organic substrate
IL208139A IL208139A0 (en) 2008-04-14 2010-09-14 Osteogenic composition including a complex growth factor/ amphiphilic polymer, a soluble cation salt, and an organic substrate
ZA2010/06627A ZA201006627B (en) 2008-04-14 2010-09-15 Osteogenic composition including a complex growth factor/amphiphilic polymer,a soluble cation salt,and an organic substrate
US13/064,092 US20110159068A1 (en) 2008-04-14 2011-03-04 Osteogenic composition comprising a growth factor/amphiphilic polymer complex, a soluble cation salt and an organic support

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0857560A FR2937863B1 (fr) 2008-11-06 2008-11-06 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et un gel

Publications (2)

Publication Number Publication Date
FR2937863A1 FR2937863A1 (fr) 2010-05-07
FR2937863B1 true FR2937863B1 (fr) 2012-05-18

Family

ID=40755852

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0857560A Expired - Fee Related FR2937863B1 (fr) 2008-04-14 2008-11-06 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et un gel

Country Status (2)

Country Link
FR (1) FR2937863B1 (fr)
RU (1) RU2010146243A (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1192700A (zh) * 1995-06-06 1998-09-09 基因科学再生实验室有限公司 改性成骨材料
US6030635A (en) * 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
FR2794649B1 (fr) * 1999-06-11 2003-04-11 Solutions Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
US7771741B2 (en) * 2006-05-01 2010-08-10 Warsaw Orthopedic, Inc Demineralized bone matrix devices

Also Published As

Publication number Publication date
FR2937863A1 (fr) 2010-05-07
RU2010146243A (ru) 2012-05-20

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Effective date: 20150731