FR2933306B1 - Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et une matrice organique - Google Patents

Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et une matrice organique

Info

Publication number
FR2933306B1
FR2933306B1 FR0854621A FR0854621A FR2933306B1 FR 2933306 B1 FR2933306 B1 FR 2933306B1 FR 0854621 A FR0854621 A FR 0854621A FR 0854621 A FR0854621 A FR 0854621A FR 2933306 B1 FR2933306 B1 FR 2933306B1
Authority
FR
France
Prior art keywords
growth factor
organic matrix
cation salt
anionic polysaccharide
soluble cation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0854621A
Other languages
English (en)
Other versions
FR2933306A1 (fr
Inventor
Olivier Soula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adocia SAS
Original Assignee
Adocia SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0854621A priority Critical patent/FR2933306B1/fr
Application filed by Adocia SAS filed Critical Adocia SAS
Priority to US12/385,605 priority patent/US20090291114A1/en
Priority to KR1020107025338A priority patent/KR20110014588A/ko
Priority to BRPI0906553-9A priority patent/BRPI0906553A2/pt
Priority to JP2011504554A priority patent/JP2011519292A/ja
Priority to AU2009237414A priority patent/AU2009237414A1/en
Priority to CA2720203A priority patent/CA2720203A1/fr
Priority to MX2010011267A priority patent/MX2010011267A/es
Priority to CN2009801132626A priority patent/CN102065882A/zh
Priority to PCT/IB2009/005235 priority patent/WO2009127940A1/fr
Priority to EP09732932A priority patent/EP2288370A1/fr
Publication of FR2933306A1 publication Critical patent/FR2933306A1/fr
Application granted granted Critical
Publication of FR2933306B1 publication Critical patent/FR2933306B1/fr
Priority to IL208139A priority patent/IL208139A0/en
Priority to ZA2010/06627A priority patent/ZA201006627B/en
Priority to US13/064,092 priority patent/US20110159068A1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/102—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0854621A 2008-04-14 2008-07-07 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et une matrice organique Expired - Fee Related FR2933306B1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR0854621A FR2933306B1 (fr) 2008-07-07 2008-07-07 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et une matrice organique
EP09732932A EP2288370A1 (fr) 2008-04-14 2009-04-14 Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation e un support organique
BRPI0906553-9A BRPI0906553A2 (pt) 2008-04-14 2009-04-14 ''implante aberto constituído por uma composição osteogênica e método de preparação do implante''
JP2011504554A JP2011519292A (ja) 2008-04-14 2009-04-14 成長因子／両親媒性ポリマー複合体、可溶性のカチオン塩及び有機支持体を含有する骨形成組成物
AU2009237414A AU2009237414A1 (en) 2008-04-14 2009-04-14 Osteogenic composition including a complex growth factor/amphiphilic polymer, a soluble cation salt, and an organic substrate
CA2720203A CA2720203A1 (fr) 2008-04-14 2009-04-14 Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation et un support organique
MX2010011267A MX2010011267A (es) 2008-04-14 2009-04-14 Composicion osteogenica que comprende un complejo del factor de crecimiento/polimero anfifilico, una sal de cation soluble y un soporte organico.
CN2009801132626A CN102065882A (zh) 2008-04-14 2009-04-14 包含生长因子/两亲性聚合物复合物、阳离子的可溶性盐和有机支持物的成骨组合物
US12/385,605 US20090291114A1 (en) 2008-04-14 2009-04-14 Osteogenic composition comprising a growth factor/amphiphilic polymer complex, a soluble cation salt and an organic support
KR1020107025338A KR20110014588A (ko) 2008-04-14 2009-04-14 성장인자/양친매성 중합체 복합체, 가용성 양이온 염 및 유기 지지체를 포함하는 골형성 조성물
PCT/IB2009/005235 WO2009127940A1 (fr) 2008-04-14 2009-04-14 Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation e un support organique
IL208139A IL208139A0 (en) 2008-04-14 2010-09-14 Osteogenic composition including a complex growth factor/ amphiphilic polymer, a soluble cation salt, and an organic substrate
ZA2010/06627A ZA201006627B (en) 2008-04-14 2010-09-15 Osteogenic composition including a complex growth factor/amphiphilic polymer,a soluble cation salt,and an organic substrate
US13/064,092 US20110159068A1 (en) 2008-04-14 2011-03-04 Osteogenic composition comprising a growth factor/amphiphilic polymer complex, a soluble cation salt and an organic support

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0854621A FR2933306B1 (fr) 2008-07-07 2008-07-07 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et une matrice organique

Publications (2)

Publication Number Publication Date
FR2933306A1 FR2933306A1 (fr) 2010-01-08
FR2933306B1 true FR2933306B1 (fr) 2010-09-10

Family

ID=40079627

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0854621A Expired - Fee Related FR2933306B1 (fr) 2008-04-14 2008-07-07 Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et une matrice organique

Country Status (1)

Country Link
FR (1) FR2933306B1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2948573B1 (fr) 2009-07-31 2011-11-18 Adocia Nouvelle forme d'administration de complexes de proteines osteogeniques
FR2958647B1 (fr) 2010-04-08 2013-08-23 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par un derive hydrophobe porte par un spacer au moins trivalent.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2222626A1 (fr) * 1995-06-06 1996-12-12 Biocoll Laboratories, Inc. Materiaux osteogeniques modifies
FR2794649B1 (fr) * 1999-06-11 2003-04-11 Solutions Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
US20070184087A1 (en) * 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US7771741B2 (en) * 2006-05-01 2010-08-10 Warsaw Orthopedic, Inc Demineralized bone matrix devices
US20080147197A1 (en) * 2006-12-14 2008-06-19 Mckay William F Biodegradable osteogenic porous biomedical implant with impermeable membrane

Also Published As

Publication number Publication date
FR2933306A1 (fr) 2010-01-08

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Effective date: 20150331