BRPI0808696A2 - Complexos de hiluronanas, outros componentes de matriz, hormônios e fatores de crescimento para manutenção, expansão e/ou diferenciação de células - Google Patents

Complexos de hiluronanas, outros componentes de matriz, hormônios e fatores de crescimento para manutenção, expansão e/ou diferenciação de células

Info

Publication number
BRPI0808696A2
BRPI0808696A2 BRPI0808696-6A BRPI0808696A BRPI0808696A2 BR PI0808696 A2 BRPI0808696 A2 BR PI0808696A2 BR PI0808696 A BRPI0808696 A BR PI0808696A BR PI0808696 A2 BRPI0808696 A2 BR PI0808696A2
Authority
BR
Brazil
Prior art keywords
hyuronan
hormones
differentiation
complexes
expansion
Prior art date
Application number
BRPI0808696-6A
Other languages
English (en)
Inventor
Lola M Reid
William S Turner
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Publication of BRPI0808696A2 publication Critical patent/BRPI0808696A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
BRPI0808696-6A 2007-03-06 2008-03-05 Complexos de hiluronanas, outros componentes de matriz, hormônios e fatores de crescimento para manutenção, expansão e/ou diferenciação de células BRPI0808696A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89327707P 2007-03-06 2007-03-06
PCT/US2008/055881 WO2008109659A2 (en) 2007-03-06 2008-03-05 Complexes of hyaluronans, other matrix components, hormones and growth factors for maintenance, expansion and/or differentiation of cells

Publications (1)

Publication Number Publication Date
BRPI0808696A2 true BRPI0808696A2 (pt) 2015-06-23

Family

ID=39671615

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0808696-6A BRPI0808696A2 (pt) 2007-03-06 2008-03-05 Complexos de hiluronanas, outros componentes de matriz, hormônios e fatores de crescimento para manutenção, expansão e/ou diferenciação de células

Country Status (9)

Country Link
US (1) US20080248570A1 (pt)
EP (1) EP2132303A2 (pt)
JP (1) JP2010519934A (pt)
CN (1) CN101855340A (pt)
BR (1) BRPI0808696A2 (pt)
CA (1) CA2680254A1 (pt)
MX (1) MX2009009582A (pt)
TW (1) TW200902716A (pt)
WO (1) WO2008109659A2 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2630355A1 (en) * 2005-11-16 2007-05-24 University Of North Carolina At Chapel Hill Extracellular matrix components for expansion or differentiation of hepatic progenitors
TW200916581A (en) * 2007-06-15 2009-04-16 Univ North Carolina Paracrine signals from mesenchymal feeder cells and regulating expansion and differentiation of hepatic progenitors using same
US8426196B2 (en) * 2008-06-05 2013-04-23 Lynn L. H. Huang Method for regulating proliferation of cells
SG10201407102QA (en) * 2009-10-30 2014-11-27 Univ North Carolina Multipotent stem cells from the extrahepatic billary tree and methods of isolating same
TW201202424A (en) * 2010-05-07 2012-01-16 Univ North Carolina Method of engrafting cells from solid tissues
JP5937070B2 (ja) * 2010-06-22 2016-06-22 ウニヴェルシテ ド ルアンＵｎｉｖｅｒｓｉｔｅ Ｄｅ Ｒｏｕｅｎ ３ｄ細胞培養に用いる改良された架橋ヒアルロナンヒドロゲル
WO2012133156A1 (ja) * 2011-03-25 2012-10-04 国立大学法人京都大学 上皮系体性幹細胞の製造方法
WO2014074859A1 (en) * 2012-11-08 2014-05-15 Ingeneron Inc. Media for culturing, preserving, and administering regenerative cells
CN103113627B (zh) * 2013-01-17 2015-03-25 黑龙江省重生生物科技有限公司 一种用于细胞培养的多糖/Matrigel复合凝胶膜及其制备方法和应用
WO2014127232A2 (en) * 2013-02-15 2014-08-21 Dcb-Usa Llc Methods for maintaining population of therapeutic cells in treatment site of subject in need of cell therapy
US9533013B2 (en) 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
US20160257937A1 (en) * 2015-03-06 2016-09-08 University Of North Carolina At Chapel Hill HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)
CN106434532A (zh) * 2016-12-22 2017-02-22 叶宗耀 一种培养肝细胞的培养基及其制备方法
CN106754659B (zh) * 2016-12-31 2020-10-30 浙江领蔚生物技术有限公司 一种维持细胞表型的肝干细胞体外高活性三维扩增方法
CA3066710A1 (en) 2017-06-12 2018-12-20 The University Of North Carolina At Chapel Hill Patch graft compositions for cell engraftment
WO2024020067A1 (en) * 2022-07-22 2024-01-25 Board Of Trustees Of Michigan State University Maturation medium compositions and methods for human heart organoid maturation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7456017B2 (en) * 1999-10-01 2008-11-25 University Of North Carolina At Chapel Hill Processes for clonal growth of hepatic progenitor cells
US20040063206A1 (en) * 2002-09-30 2004-04-01 Rowley Jon A. Programmable scaffold and method for making and using the same
WO2006033103A2 (en) * 2004-09-21 2006-03-30 Nvr Labs. Ltd. Compositions and methods for stem cell expansion and differentiation
CA2630355A1 (en) * 2005-11-16 2007-05-24 University Of North Carolina At Chapel Hill Extracellular matrix components for expansion or differentiation of hepatic progenitors

Also Published As

Publication number Publication date
MX2009009582A (es) 2009-10-26
CA2680254A1 (en) 2008-09-12
JP2010519934A (ja) 2010-06-10
EP2132303A2 (en) 2009-12-16
US20080248570A1 (en) 2008-10-09
CN101855340A (zh) 2010-10-06
WO2008109659A3 (en) 2008-10-30
WO2008109659A2 (en) 2008-09-12
TW200902716A (en) 2009-01-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.