JP2011511778A5 - - Google Patents
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- JP2011511778A5 JP2011511778A5 JP2010545058A JP2010545058A JP2011511778A5 JP 2011511778 A5 JP2011511778 A5 JP 2011511778A5 JP 2010545058 A JP2010545058 A JP 2010545058A JP 2010545058 A JP2010545058 A JP 2010545058A JP 2011511778 A5 JP2011511778 A5 JP 2011511778A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- amino acid
- chain
- acid
- insulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 0 CNC(**=I)=O Chemical compound CNC(**=I)=O 0.000 description 6
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2467208P | 2008-01-30 | 2008-01-30 | |
| PCT/US2009/031593 WO2009099763A1 (en) | 2008-01-30 | 2009-01-21 | Ester-based peptide prodrugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011511778A JP2011511778A (ja) | 2011-04-14 |
| JP2011511778A5 true JP2011511778A5 (enExample) | 2013-02-14 |
Family
ID=40952419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545058A Pending JP2011511778A (ja) | 2008-01-30 | 2009-01-21 | エステルに基づいたペプチドプロドラッグ |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20110065633A1 (enExample) |
| EP (1) | EP2249853A4 (enExample) |
| JP (1) | JP2011511778A (enExample) |
| CN (1) | CN101983066B (enExample) |
| AR (1) | AR073335A1 (enExample) |
| AU (1) | AU2009210570B2 (enExample) |
| CA (1) | CA2713348C (enExample) |
| CL (1) | CL2009000202A1 (enExample) |
| PA (1) | PA8814001A1 (enExample) |
| PE (1) | PE20091440A1 (enExample) |
| TW (1) | TW200938225A (enExample) |
| WO (1) | WO2009099763A1 (enExample) |
Families Citing this family (104)
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| JP6017754B2 (ja) | 2007-02-15 | 2016-11-02 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | グルカゴン/glp−1受容体コアゴニスト |
| EP2217701B9 (en) | 2007-10-30 | 2015-02-18 | Indiana University Research and Technology Corporation | Glucagon antagonists |
| CA2702289A1 (en) | 2007-10-30 | 2009-05-07 | Indiana University Research And Technology Corporation | Compounds exhibiting glucagon antagonist and glp-1 agonist activity |
| EP2249853A4 (en) | 2008-01-30 | 2012-12-26 | Univ Indiana Res & Tech Corp | ESTER BASED PEPTIDE PRODRUGS |
| JP5753779B2 (ja) | 2008-06-17 | 2015-07-22 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | 生理学的pHの緩衝液中で向上した溶解性及び安定性を示すグルカゴン類縁体 |
| BRPI0915282A2 (pt) | 2008-06-17 | 2017-02-07 | Univ Indiana Res & Tech Corp | agonistas mistos baseados no gip para o tratamento de distúrbios metabólicos e obesidade |
| AU2009260302B2 (en) | 2008-06-17 | 2014-10-23 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
| WO2010080606A1 (en) | 2008-12-19 | 2010-07-15 | Indiana University Research And Technology Corporation | Insulin analogs |
| CN102245624B (zh) | 2008-12-19 | 2016-08-10 | 印第安纳大学研究及科技有限公司 | 基于酰胺的胰岛素前药 |
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| US8946147B2 (en) | 2010-06-24 | 2015-02-03 | Indiana University Research And Technology Corporation | Amide-based insulin prodrugs |
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| EA031230B1 (ru) | 2011-06-22 | 2018-12-28 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Агонисты глюкагонового рецептора/glp-1-рецептора |
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| US9573987B2 (en) | 2011-12-20 | 2017-02-21 | Indiana University Research And Technology Corporation | CTP-based insulin analogs for treatment of diabetes |
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| CN108383902A (zh) | 2012-09-26 | 2018-08-10 | 印第安纳大学研究及科技有限公司 | 胰岛素类似物二聚体 |
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-
2009
- 2009-01-21 EP EP09708686A patent/EP2249853A4/en not_active Withdrawn
- 2009-01-21 WO PCT/US2009/031593 patent/WO2009099763A1/en not_active Ceased
- 2009-01-21 US US12/865,058 patent/US20110065633A1/en not_active Abandoned
- 2009-01-21 CN CN200980112047.4A patent/CN101983066B/zh not_active Expired - Fee Related
- 2009-01-21 AU AU2009210570A patent/AU2009210570B2/en not_active Ceased
- 2009-01-21 JP JP2010545058A patent/JP2011511778A/ja active Pending
- 2009-01-21 CA CA2713348A patent/CA2713348C/en not_active Expired - Fee Related
- 2009-01-23 TW TW098103051A patent/TW200938225A/zh unknown
- 2009-01-29 PA PA20098814001A patent/PA8814001A1/es unknown
- 2009-01-29 PE PE2009000119A patent/PE20091440A1/es not_active Application Discontinuation
- 2009-01-30 CL CL2009000202A patent/CL2009000202A1/es unknown
- 2009-01-30 AR ARP090100301A patent/AR073335A1/es unknown
-
2010
- 2010-07-28 US US12/845,455 patent/US8697838B2/en not_active Expired - Fee Related
-
2014
- 2014-02-18 US US14/182,706 patent/US9089539B2/en not_active Expired - Fee Related
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