JP2011504501A5 - - Google Patents
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- Publication number
- JP2011504501A5 JP2011504501A5 JP2010534969A JP2010534969A JP2011504501A5 JP 2011504501 A5 JP2011504501 A5 JP 2011504501A5 JP 2010534969 A JP2010534969 A JP 2010534969A JP 2010534969 A JP2010534969 A JP 2010534969A JP 2011504501 A5 JP2011504501 A5 JP 2011504501A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nos
- cdr sequences
- cdr
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US403707P | 2007-11-21 | 2007-11-21 | |
| US61/004,037 | 2007-11-21 | ||
| PCT/US2008/012987 WO2009070243A2 (en) | 2007-11-21 | 2008-11-21 | Wise binding agents and epitopes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014061293A Division JP2014167002A (ja) | 2007-11-21 | 2014-03-25 | Wise結合抗体及びエピトープ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011504501A JP2011504501A (ja) | 2011-02-10 |
| JP2011504501A5 true JP2011504501A5 (enExample) | 2012-01-12 |
| JP5583591B2 JP5583591B2 (ja) | 2014-09-03 |
Family
ID=40524859
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010534969A Expired - Fee Related JP5583591B2 (ja) | 2007-11-21 | 2008-11-21 | Wise結合抗体及びエピトープ |
| JP2014061293A Withdrawn JP2014167002A (ja) | 2007-11-21 | 2014-03-25 | Wise結合抗体及びエピトープ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014061293A Withdrawn JP2014167002A (ja) | 2007-11-21 | 2014-03-25 | Wise結合抗体及びエピトープ |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8043620B2 (enExample) |
| EP (1) | EP2220118A2 (enExample) |
| JP (2) | JP5583591B2 (enExample) |
| KR (1) | KR20100099193A (enExample) |
| CN (1) | CN101925611A (enExample) |
| AU (1) | AU2008330125B2 (enExample) |
| BR (1) | BRPI0820387A2 (enExample) |
| CA (1) | CA2705879A1 (enExample) |
| CO (1) | CO6311002A2 (enExample) |
| CR (1) | CR11523A (enExample) |
| EA (1) | EA201000844A1 (enExample) |
| IL (1) | IL205569A0 (enExample) |
| MA (1) | MA31918B1 (enExample) |
| MX (1) | MX2010005656A (enExample) |
| TN (1) | TN2010000213A1 (enExample) |
| WO (1) | WO2009070243A2 (enExample) |
| ZA (1) | ZA201003578B (enExample) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008507288A (ja) | 2004-07-23 | 2008-03-13 | アクセルロン ファーマ インコーポレーテッド | ActRII受容体ポリペプチド、方法、および組成物 |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| BRPI0618947B1 (pt) | 2005-11-23 | 2022-07-19 | Acceleron Pharma Inc | Polipeptídeo actriia que se liga à ativina, polinucleotídeo isolado, polinucleotídeo recombinante, métodopara preparar um polipeptídeo actriia que se liga à ativina, preparação farmacêutica e uso de uma proteína de fusão actriia-fc para promover o crescimento ósseo e inibir a ressorção óssea |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| TWI584815B (zh) | 2007-02-01 | 2017-06-01 | 艾瑟勒朗法瑪公司 | 活化素-ActRIIa拮抗劑及其治療或預防乳癌之用途 |
| TW201627320A (zh) | 2007-02-02 | 2016-08-01 | 艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
| MX2009008510A (es) | 2007-02-09 | 2010-01-15 | Acceleron Pharma Inc | Antagonistas de activina-actriia y usos para promover el crecimiento de huesos en pacientes con cancer. |
| CA2699936A1 (en) | 2007-09-18 | 2009-03-26 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| DK3750552T5 (da) | 2008-08-14 | 2024-08-26 | Acceleron Pharma Inc | Gdf-fælder |
| WO2011063127A1 (en) | 2009-11-18 | 2011-05-26 | University Of Medicine And Dentistry Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| AU2010204985A1 (en) | 2009-01-13 | 2011-08-04 | Acceleron Pharma Inc. | Methods for increasing adiponectin |
| MX355042B (es) | 2009-06-08 | 2018-04-02 | Acceleon Pharma Inc | Metodos para aumentar adipositos termogenicos. |
| CN107267520A (zh) | 2009-06-12 | 2017-10-20 | 阿塞勒隆制药公司 | 截短的actriib‑fc融合蛋白 |
| CA2771575A1 (en) | 2009-08-29 | 2011-03-03 | Abbott Laboratories | Therapeutic dll4 binding proteins |
| ES2658292T3 (es) | 2009-11-17 | 2018-03-09 | Acceleron Pharma, Inc. | Proteínas ActRIIB y variantes y usos de las mismas con respecto a la inducción de la utrofina para el tratamiento de la distrofia muscular |
| US9849192B2 (en) | 2009-11-18 | 2017-12-26 | Rutgers, The State University Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| CA2781682A1 (en) * | 2009-12-04 | 2011-06-09 | Genentech, Inc. | Multispecific antibodies, antibody analogs, compositions, and methods |
| US20120288507A1 (en) | 2009-12-18 | 2012-11-15 | Amgen Inc. | Wise binding agents and epitopes |
| WO2011109298A2 (en) | 2010-03-02 | 2011-09-09 | Abbott Laboratories | Therapeutic dll4 binding proteins |
| CA2817008A1 (en) | 2010-11-08 | 2012-05-18 | Acceleron Pharma Inc. | Actriia binding agents and uses thereof |
| AU2012327223A1 (en) | 2011-11-30 | 2013-06-20 | Wellstat Diagnostics, Llc. | Assays, antibodies, immunogens and compositions related to 5-FU |
| TW201333040A (zh) * | 2012-01-06 | 2013-08-16 | Bioalliance Cv | 抗-輸鐵蛋白受器之抗體及其使用方法 |
| FR2987293B1 (fr) * | 2012-02-27 | 2014-03-07 | Michelin & Cie | Procede et appareil pour realiser des objets tridimensionnels a proprietes ameliorees |
| EP2904015A4 (en) * | 2012-10-02 | 2016-10-05 | Univ Rutgers | TARGETED RELEASE OF ANTIBODIES TO ACTIVATED MATRIPTASE-CONJUGATED TOXINS |
| RU2678117C2 (ru) | 2012-11-02 | 2019-01-23 | Селджин Корпорейшн | Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений |
| KR102149206B1 (ko) | 2012-11-08 | 2020-08-31 | 세센 바이오, 아이엔씨. | 인터루킨-6의 길항제 및 이의 용도 |
| US20140171356A1 (en) * | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
| AU2014315081A1 (en) | 2013-09-05 | 2016-03-24 | Duke University | Nav1.7 antibodies and methods of using the same |
| US10035847B2 (en) | 2013-10-02 | 2018-07-31 | The Rockefeller University | Amyloid protofibril antibodies and methods of use thereof |
| CN114699529A (zh) | 2014-06-13 | 2022-07-05 | 阿塞勒隆制药公司 | 用于治疗溃疡的方法和组合物 |
| MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
| SI3215530T1 (sl) | 2014-11-07 | 2020-02-28 | Sesen Bio, Inc. | Izboljšana protitelesa IL-6 |
| EP3227675B1 (en) | 2014-12-03 | 2023-03-15 | Celgene Corporation | Activin-actrii antagonists and uses for treating myelodysplastic syndrome |
| BR112018017031A2 (pt) | 2016-02-23 | 2019-01-22 | Sesen Bio Inc | formulações de antagonista de il-6 e usos das mesmas |
| IL261757B2 (en) | 2016-03-18 | 2023-09-01 | Univ Rutgers | Treatment of stem cells with chemotherapeutic agents conjugated to anti-matriptase antibodies using connecting parts that can be broken down in the living body |
| WO2017189963A1 (en) * | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| CA3049967C (en) * | 2017-01-06 | 2024-10-01 | The Regents Of The University Of California | ANTI-IgE ANTIBODIES: THERAPIES AND ASSOCIATED METHODS AND COMPOSITIONS |
| JP7795860B2 (ja) | 2017-09-07 | 2026-01-08 | オーガスタ ユニバーシティ リサーチ インスティテュート,インコーポレーテッド | プログラム細胞死タンパク質1に対する抗体 |
| JP7572668B2 (ja) * | 2019-07-12 | 2024-10-24 | 国立大学法人京都大学 | 歯の再生治療のためのusag-1を標的分子とした中和抗体 |
| CN112180099B (zh) * | 2020-09-15 | 2022-07-29 | 江南大学附属医院 | 子宫内膜异位症血清标志物的应用 |
| WO2023147470A2 (en) | 2022-01-28 | 2023-08-03 | Georgiamune Inc. | Antibodies to programmed cell death protein 1 that are pd-1 agonists |
| CN115322258B (zh) * | 2022-05-31 | 2024-08-13 | 武汉真福医药股份有限公司 | 一种单克隆抗体qkma-1g41及其应用 |
| CN115304677B (zh) * | 2022-06-19 | 2024-08-16 | 湖北真福医药有限公司 | 一种抗枯草芽孢杆菌纤溶酶的单克隆抗体qkma-9a10及应用 |
| CN116712533B (zh) * | 2023-07-03 | 2024-02-02 | 广东暨安特博生物科技有限公司 | 一种sostdc1蛋白在制备治疗皮肤病产品中的应用 |
| US20260184784A1 (en) * | 2024-09-26 | 2026-07-02 | The Trustees Of Indiana University | Antibodies for multiple myeloma treatment |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2220912A1 (en) * | 1995-06-05 | 1996-12-12 | Gregg A. Hastings | Human ccn-like growth factor |
| CA2416538A1 (en) * | 2000-07-20 | 2002-01-31 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| US20040023356A1 (en) * | 2002-06-14 | 2004-02-05 | Robb Krumlauf | Wise/Sost nucleic acid sequences and amino acid sequences |
| CA2560889A1 (en) * | 2004-03-23 | 2005-10-13 | Sanjay D. Khare | Monoclonal antibodies specific for human ox40l (cd 134l) |
| SI3345607T1 (sl) * | 2006-12-29 | 2023-03-31 | Ossifi-Mab Llc | Postopki spreminjanja rasti kosti z dajanjem antagonista ali agonista SOST ali WISE |
| PT2170959E (pt) * | 2007-06-18 | 2014-01-07 | Merck Sharp & Dohme | Anticorpos para o receptor humano de morte programada pd-1 |
| JO3382B1 (ar) * | 2008-12-23 | 2019-03-13 | Amgen Inc | أجسام مضادة ترتبط مع مستقبل cgrp بشري |
| AR076668A1 (es) * | 2009-05-12 | 2011-06-29 | Pfizer | Anticuerpos especificos para dkk-1 y sus usos |
-
2008
- 2008-11-21 CN CN2008801252375A patent/CN101925611A/zh active Pending
- 2008-11-21 JP JP2010534969A patent/JP5583591B2/ja not_active Expired - Fee Related
- 2008-11-21 AU AU2008330125A patent/AU2008330125B2/en not_active Ceased
- 2008-11-21 BR BRPI0820387-3A patent/BRPI0820387A2/pt not_active IP Right Cessation
- 2008-11-21 WO PCT/US2008/012987 patent/WO2009070243A2/en not_active Ceased
- 2008-11-21 KR KR1020107013609A patent/KR20100099193A/ko not_active Withdrawn
- 2008-11-21 EA EA201000844A patent/EA201000844A1/ru unknown
- 2008-11-21 US US12/275,850 patent/US8043620B2/en not_active Expired - Fee Related
- 2008-11-21 EP EP08855691A patent/EP2220118A2/en not_active Withdrawn
- 2008-11-21 CA CA2705879A patent/CA2705879A1/en not_active Abandoned
- 2008-11-21 MX MX2010005656A patent/MX2010005656A/es active IP Right Grant
-
2010
- 2010-05-05 IL IL205569A patent/IL205569A0/en unknown
- 2010-05-14 TN TN2010000213A patent/TN2010000213A1/fr unknown
- 2010-05-20 ZA ZA2010/03578A patent/ZA201003578B/en unknown
- 2010-06-15 MA MA32918A patent/MA31918B1/fr unknown
- 2010-06-21 CR CR11523A patent/CR11523A/es not_active Application Discontinuation
- 2010-06-23 CO CO10075718A patent/CO6311002A2/es not_active Application Discontinuation
-
2011
- 2011-09-15 US US13/233,983 patent/US8309092B2/en active Active
-
2014
- 2014-03-25 JP JP2014061293A patent/JP2014167002A/ja not_active Withdrawn
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