CA2705879A1 - Wise binding agents and epitopes - Google Patents
Wise binding agents and epitopes Download PDFInfo
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- CA2705879A1 CA2705879A1 CA2705879A CA2705879A CA2705879A1 CA 2705879 A1 CA2705879 A1 CA 2705879A1 CA 2705879 A CA2705879 A CA 2705879A CA 2705879 A CA2705879 A CA 2705879A CA 2705879 A1 CA2705879 A1 CA 2705879A1
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- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US403707P | 2007-11-21 | 2007-11-21 | |
| US61/004,037 | 2007-11-21 | ||
| PCT/US2008/012987 WO2009070243A2 (en) | 2007-11-21 | 2008-11-21 | Wise binding agents and epitopes |
Publications (1)
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| CA2705879A1 true CA2705879A1 (en) | 2009-06-04 |
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|---|---|---|---|
| CA2705879A Abandoned CA2705879A1 (en) | 2007-11-21 | 2008-11-21 | Wise binding agents and epitopes |
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| JP (2) | JP5583591B2 (enExample) |
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| BR (1) | BRPI0820387A2 (enExample) |
| CA (1) | CA2705879A1 (enExample) |
| CO (1) | CO6311002A2 (enExample) |
| CR (1) | CR11523A (enExample) |
| EA (1) | EA201000844A1 (enExample) |
| IL (1) | IL205569A0 (enExample) |
| MA (1) | MA31918B1 (enExample) |
| MX (1) | MX2010005656A (enExample) |
| TN (1) | TN2010000213A1 (enExample) |
| WO (1) | WO2009070243A2 (enExample) |
| ZA (1) | ZA201003578B (enExample) |
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| EP1771470B1 (en) | 2004-07-23 | 2013-06-26 | Acceleron Pharma Inc. | Actrii receptor polypeptides, methods and compositions |
| RS58231B1 (sr) | 2005-11-23 | 2019-03-29 | Acceleron Pharma Inc | Antagonisti aktivin-actriia i primene za stimulaciju rasta kostiju |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| KR101526613B1 (ko) | 2007-02-01 | 2015-06-26 | 악셀레론 파마 인코포레이티드 | 액티빈-ａｃｔｒⅱａ 길항제 및 유방암을 치료 또는 예방하기 위한 이들의 용도 |
| TW201940502A (zh) | 2007-02-02 | 2019-10-16 | 美商艾瑟勒朗法瑪公司 | 衍生自ＡｃｔＲＩＩＢ的變體與其用途 |
| TW201808334A (zh) | 2007-02-09 | 2018-03-16 | 艾瑟勒朗法瑪公司 | 包含ＡｃｔＲＩＩａ-Ｆｃ融合蛋白的醫藥組合物；ＡｃｔＲＩＩａ-Ｆｃ融合蛋白於治療或預防與癌症相關的骨質流失之用途；ＡｃｔＲＩＩａ-Ｆｃ融合蛋白於治療或預防多發性骨髓瘤之用途 |
| EP2207562B1 (en) | 2007-09-18 | 2017-05-31 | Acceleron Pharma, Inc. | Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| HUE063136T2 (hu) | 2008-08-14 | 2023-12-28 | Acceleron Pharma Inc | GDF-Csapdák |
| CA2749544A1 (en) | 2009-01-13 | 2010-07-22 | Acceleron Pharma Inc. | Methods for increasing adiponectin |
| KR20120049214A (ko) | 2009-06-08 | 2012-05-16 | 악셀레론 파마 인코포레이티드 | 발열성 지방세포를 증가시키는 방법 |
| US8293881B2 (en) | 2009-06-12 | 2012-10-23 | Acceleron Pharma Inc. | Isolated nucleic acid encoding a truncated ActRIIB fusion protein |
| EP2470568A2 (en) | 2009-08-29 | 2012-07-04 | Abbott Laboratories | Therapeutic dll4 binding proteins |
| WO2011063018A1 (en) | 2009-11-17 | 2011-05-26 | Acceleron Pharma Inc. | Actriib proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy |
| US9849192B2 (en) | 2009-11-18 | 2017-12-26 | Rutgers, The State University Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| CA2818237C (en) | 2009-11-18 | 2021-05-18 | University Of Medicine And Dentistry Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| CN102770456B (zh) * | 2009-12-04 | 2018-04-06 | 弗·哈夫曼-拉罗切有限公司 | 多特异性抗体、抗体类似物、组合物和方法 |
| WO2011075636A2 (en) | 2009-12-18 | 2011-06-23 | Amgen Inc. | Wise binding agents and epitopes |
| NZ602734A (en) * | 2010-03-02 | 2014-10-31 | Abbvie Inc | Therapeutic dll4 binding proteins |
| CN103298832A (zh) | 2010-11-08 | 2013-09-11 | 阿塞勒隆制药公司 | Actriia结合剂及其用途 |
| WO2013082463A2 (en) * | 2011-11-30 | 2013-06-06 | Wellstat Diagnostics, Llc. | Assays, antibodies, immunogens and compositions related to 5-fu |
| TW201333040A (zh) * | 2012-01-06 | 2013-08-16 | Bioalliance Cv | 抗－輸鐵蛋白受器之抗體及其使用方法 |
| FR2987293B1 (fr) * | 2012-02-27 | 2014-03-07 | Michelin & Cie | Procede et appareil pour realiser des objets tridimensionnels a proprietes ameliorees |
| CA2887037A1 (en) * | 2012-10-02 | 2014-04-10 | Rutgers, The State University Of New Jersey | Specific delivery of toxins conjugated with antibodies to activated matriptase |
| MX366336B (es) | 2012-11-02 | 2019-07-05 | Celgene Corp | Antagonistas de activina - actrii y usos para el tratar trastornos oseos y otros. |
| RU2670943C9 (ru) * | 2012-11-08 | 2018-11-26 | Илэвэн Байотерапьютикс, Инк. | Антагонисты ил-6 и их применение |
| US20140171356A1 (en) * | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
| EP3041869A1 (en) | 2013-09-05 | 2016-07-13 | Duke University | Nav1.7 antibodies and methods of using the same |
| US10035847B2 (en) | 2013-10-02 | 2018-07-31 | The Rockefeller University | Amyloid protofibril antibodies and methods of use thereof |
| TN2016000553A1 (en) | 2014-06-13 | 2018-04-04 | Acceleron Pharma Inc | Methods and compositions for treating ulcers |
| MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
| SI3215530T1 (sl) | 2014-11-07 | 2020-02-28 | Sesen Bio, Inc. | Izboljšana protitelesa IL-6 |
| IL252631B2 (en) | 2014-12-03 | 2024-06-01 | Celgene Corp | ACTIVIN-ACTRII antagonists and uses for the treatment of anemia |
| AR107708A1 (es) | 2016-02-23 | 2018-05-23 | Eleven Biotherapeutics Inc | Formulaciones de antagonista de il-6 y sus usos |
| CA3017958C (en) | 2016-03-18 | 2024-03-12 | Rutgers, The State University Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to anti-matriptase antibodies by in vivo cleavable linking moieties |
| US20190224339A1 (en) * | 2016-04-29 | 2019-07-25 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| JP7128191B2 (ja) * | 2017-01-06 | 2022-08-30 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 治療抗ＩｇＥ抗体並びにその方法及び組成物 |
| WO2019051164A1 (en) | 2017-09-07 | 2019-03-14 | Augusta University Research Institute, Inc. | ANTIBODIES AGAINST PROTEIN 1 OF PROGRAMMED CELL DEATH |
| JP7572668B2 (ja) * | 2019-07-12 | 2024-10-24 | 国立大学法人京都大学 | 歯の再生治療のためのｕｓａｇ－１を標的分子とした中和抗体 |
| CN112180099B (zh) * | 2020-09-15 | 2022-07-29 | 江南大学附属医院 | 子宫内膜异位症血清标志物的应用 |
| EP4466291A4 (en) | 2022-01-28 | 2025-07-16 | Georgiamune Inc | ANTIBODIES DIRECTED AGAINST PROGRAMMED CELL DEATH PROTEIN 1, PD-1 AGONISTS |
| CN115322258B (zh) * | 2022-05-31 | 2024-08-13 | 武汉真福医药股份有限公司 | 一种单克隆抗体qkma-1g41及其应用 |
| CN115304677B (zh) * | 2022-06-19 | 2024-08-16 | 湖北真福医药有限公司 | 一种抗枯草芽孢杆菌纤溶酶的单克隆抗体qkma-9a10及应用 |
| CN116712533B (zh) * | 2023-07-03 | 2024-02-02 | 广东暨安特博生物科技有限公司 | 一种sostdc1蛋白在制备治疗皮肤病产品中的应用 |
Family Cites Families (8)
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|---|---|---|---|---|
| CA2220912A1 (en) * | 1995-06-05 | 1996-12-12 | Gregg A. Hastings | Human ccn-like growth factor |
| JP2004516013A (ja) * | 2000-07-20 | 2004-06-03 | ジェネンテック・インコーポレーテッド | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| US20040023356A1 (en) * | 2002-06-14 | 2004-02-05 | Robb Krumlauf | Wise/Sost nucleic acid sequences and amino acid sequences |
| AU2005229009A1 (en) * | 2004-03-23 | 2005-10-13 | Amgen, Inc. | Monoclonal antibodies specific for human OX40L (CD 134L) |
| EP2144613B1 (en) * | 2006-12-29 | 2018-03-21 | OstéoQC Inc. | Methods of altering bone growth by administration of sost or wise antagonist or agonist |
| CN104945508B (zh) * | 2007-06-18 | 2019-02-22 | 默沙东有限责任公司 | 针对人程序性死亡受体pd-1的抗体 |
| JO3382B1 (ar) * | 2008-12-23 | 2019-03-13 | Amgen Inc | أجسام مضادة ترتبط مع مستقبل cgrp بشري |
| KR101471239B1 (ko) * | 2009-05-12 | 2014-12-09 | 화이자 인코포레이티드 | 항-ｄｋｋ-1 항체의 차단 및 그의 용도 |
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2008
- 2008-11-21 JP JP2010534969A patent/JP5583591B2/ja not_active Expired - Fee Related
- 2008-11-21 MX MX2010005656A patent/MX2010005656A/es active IP Right Grant
- 2008-11-21 EP EP08855691A patent/EP2220118A2/en not_active Withdrawn
- 2008-11-21 BR BRPI0820387-3A patent/BRPI0820387A2/pt not_active IP Right Cessation
- 2008-11-21 US US12/275,850 patent/US8043620B2/en not_active Expired - Fee Related
- 2008-11-21 WO PCT/US2008/012987 patent/WO2009070243A2/en not_active Ceased
- 2008-11-21 CN CN2008801252375A patent/CN101925611A/zh active Pending
- 2008-11-21 CA CA2705879A patent/CA2705879A1/en not_active Abandoned
- 2008-11-21 KR KR1020107013609A patent/KR20100099193A/ko not_active Withdrawn
- 2008-11-21 AU AU2008330125A patent/AU2008330125B2/en not_active Ceased
- 2008-11-21 EA EA201000844A patent/EA201000844A1/ru unknown
-
2010
- 2010-05-05 IL IL205569A patent/IL205569A0/en unknown
- 2010-05-14 TN TN2010000213A patent/TN2010000213A1/fr unknown
- 2010-05-20 ZA ZA2010/03578A patent/ZA201003578B/en unknown
- 2010-06-15 MA MA32918A patent/MA31918B1/fr unknown
- 2010-06-21 CR CR11523A patent/CR11523A/es not_active Application Discontinuation
- 2010-06-23 CO CO10075718A patent/CO6311002A2/es not_active Application Discontinuation
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2011
- 2011-09-15 US US13/233,983 patent/US8309092B2/en active Active
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2014
- 2014-03-25 JP JP2014061293A patent/JP2014167002A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CR11523A (es) | 2010-12-16 |
| MA31918B1 (fr) | 2010-12-01 |
| EP2220118A2 (en) | 2010-08-25 |
| AU2008330125B2 (en) | 2012-11-22 |
| BRPI0820387A2 (pt) | 2015-05-26 |
| CN101925611A (zh) | 2010-12-22 |
| TN2010000213A1 (en) | 2011-11-11 |
| US8043620B2 (en) | 2011-10-25 |
| WO2009070243A3 (en) | 2009-10-29 |
| JP2011504501A (ja) | 2011-02-10 |
| US8309092B2 (en) | 2012-11-13 |
| MX2010005656A (es) | 2010-11-12 |
| JP2014167002A (ja) | 2014-09-11 |
| US20120003237A1 (en) | 2012-01-05 |
| ZA201003578B (en) | 2011-04-28 |
| WO2009070243A2 (en) | 2009-06-04 |
| EA201000844A1 (ru) | 2011-10-31 |
| CO6311002A2 (es) | 2011-08-22 |
| US20090130114A1 (en) | 2009-05-21 |
| AU2008330125A1 (en) | 2009-06-04 |
| KR20100099193A (ko) | 2010-09-10 |
| IL205569A0 (en) | 2010-12-30 |
| JP5583591B2 (ja) | 2014-09-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20151123 |