MA31918B1 - Agents et épitopes de liaison à wise - Google Patents
Agents et épitopes de liaison à wiseInfo
- Publication number
- MA31918B1 MA31918B1 MA32918A MA32918A MA31918B1 MA 31918 B1 MA31918 B1 MA 31918B1 MA 32918 A MA32918 A MA 32918A MA 32918 A MA32918 A MA 32918A MA 31918 B1 MA31918 B1 MA 31918B1
- Authority
- MA
- Morocco
- Prior art keywords
- wise
- agents
- epiopes
- connection
- manufacture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La présente invention concerne des agents de liaison pour wise, et comprend leur fabrication et leur utilisation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US403707P | 2007-11-21 | 2007-11-21 | |
PCT/US2008/012987 WO2009070243A2 (fr) | 2007-11-21 | 2008-11-21 | Agents et épitopes de liaison à wise |
Publications (1)
Publication Number | Publication Date |
---|---|
MA31918B1 true MA31918B1 (fr) | 2010-12-01 |
Family
ID=40524859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA32918A MA31918B1 (fr) | 2007-11-21 | 2010-06-15 | Agents et épitopes de liaison à wise |
Country Status (17)
Country | Link |
---|---|
US (2) | US8043620B2 (fr) |
EP (1) | EP2220118A2 (fr) |
JP (2) | JP5583591B2 (fr) |
KR (1) | KR20100099193A (fr) |
CN (1) | CN101925611A (fr) |
AU (1) | AU2008330125B2 (fr) |
BR (1) | BRPI0820387A2 (fr) |
CA (1) | CA2705879A1 (fr) |
CO (1) | CO6311002A2 (fr) |
CR (1) | CR11523A (fr) |
EA (1) | EA201000844A1 (fr) |
IL (1) | IL205569A0 (fr) |
MA (1) | MA31918B1 (fr) |
MX (1) | MX2010005656A (fr) |
TN (1) | TN2010000213A1 (fr) |
WO (1) | WO2009070243A2 (fr) |
ZA (1) | ZA201003578B (fr) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2332977T3 (en) | 2004-07-23 | 2016-02-29 | Acceleron Pharma Inc | ActRII receptor polypeptides |
EP3811965A1 (fr) | 2005-11-23 | 2021-04-28 | Acceleron Pharma, Inc. | Antagonistes de l'activine-actriia destinés à être utilisés pour la promotion de la croissance osseuse |
US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
ES2415666T3 (es) | 2007-02-01 | 2013-07-26 | Acceleron Pharma, Inc. | Composiciones farmacéuticas que comprenden antagonistas de Activina-ActRIIa para uso en la prevención o el tratamiento de metástasis de cáncer de mama o pérdida ósea relacionada con el cáncer de mama |
TW202104248A (zh) | 2007-02-02 | 2021-02-01 | 美商艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
TW201934141A (zh) | 2007-02-09 | 2019-09-01 | 美商艾瑟勒朗法瑪公司 | 包含ActRIIa-Fc融合蛋白的醫藥組合物;ActRIIa-Fc融合蛋白於治療或預防與癌症相關的骨質流失之用途;ActRIIa-Fc融合蛋白於治療或預防多發性骨髓瘤之用途 |
EP2207562B1 (fr) | 2007-09-18 | 2017-05-31 | Acceleron Pharma, Inc. | Antagonistes de l'activine-actriia et utilisations pour réduire ou empêcher la sécrétion de fsh |
US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
PL2340031T4 (pl) | 2008-08-14 | 2020-12-28 | Acceleron Pharma Inc. | Zastosowanie pułapek GDF do leczenia niedokrwistości |
WO2010083034A1 (fr) | 2009-01-13 | 2010-07-22 | Acceleron Pharma Inc. | Procédés permettant d'augmenter l'adiponectine |
MX355042B (es) | 2009-06-08 | 2018-04-02 | Acceleon Pharma Inc | Metodos para aumentar adipositos termogenicos. |
EP2440577A4 (fr) | 2009-06-12 | 2013-01-23 | Acceleron Pharma Inc | Protéines de fusion actriib-fc tronquées |
PE20121647A1 (es) | 2009-08-29 | 2012-12-31 | Abbvie Inc | Proteinas terapeuticas de union a dll4 |
CA2781152A1 (fr) | 2009-11-17 | 2011-05-26 | Acceleron Pharma Inc. | Proteines actriib et variants et utilisations de celles-ci se rapportant a l'induction de l'utrophine pour une therapie de la dystrophie musculaire |
US9849192B2 (en) | 2009-11-18 | 2017-12-26 | Rutgers, The State University Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
CA2818237C (fr) | 2009-11-18 | 2021-05-18 | University Of Medicine And Dentistry Of New Jersey | Ciblage de cellules tumorales par des agents chimiotherapeutiques conjugues a des anticorps diriges contre la matriptase |
RU2016105962A (ru) * | 2009-12-04 | 2018-11-23 | Дженентек, Инк. | Мультиспецифические антитела, аналоги антител, композиции и способы |
EP2512600A2 (fr) | 2009-12-18 | 2012-10-24 | Amgen Inc. | Épitopes et agents de liaison destinés à wise |
WO2011109298A2 (fr) * | 2010-03-02 | 2011-09-09 | Abbott Laboratories | Protéines thérapeutiques de liaison à dll4 |
WO2012064771A1 (fr) | 2010-11-08 | 2012-05-18 | Acceleron Pharma, Inc. | Agents de liaison à actriia et leurs utilisations |
CA2857645A1 (fr) | 2011-11-30 | 2013-06-06 | Wellstat Diagnostics, Llc | Dosages, anticorps, immunogenes et compositions se rapportant a 5-fu |
AU2013203422A1 (en) * | 2012-01-06 | 2013-07-18 | Bioalliance C.V. | Anti-transferrin receptor antibodies and methods using same |
FR2987293B1 (fr) * | 2012-02-27 | 2014-03-07 | Michelin & Cie | Procede et appareil pour realiser des objets tridimensionnels a proprietes ameliorees |
WO2014055663A1 (fr) * | 2012-10-02 | 2014-04-10 | Rutgers, The State University Of New Jersey | Administration spécifique de toxines conjuguées à des anticorps jusqu'à la matriptase activée |
ES2884095T3 (es) | 2012-11-02 | 2021-12-10 | Celgene Corp | Antagonistas de activina-actrii y usos para el tratamiento de trastornos óseos y otros trastornos |
MX2015005831A (es) * | 2012-11-08 | 2015-09-24 | Eleven Biotherapeutics Inc | Antagonistas de il-6 y usos de los mismos. |
US20140171356A1 (en) * | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
AU2014315081A1 (en) | 2013-09-05 | 2016-03-24 | Duke University | Nav1.7 antibodies and methods of using the same |
WO2015051159A1 (fr) * | 2013-10-02 | 2015-04-09 | The Rockefeller University | Anticorps de protofibrilles amyloïdes et leurs procédés d'utilisation |
CN114699529A (zh) | 2014-06-13 | 2022-07-05 | 阿塞勒隆制药公司 | 用于治疗溃疡的方法和组合物 |
MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
DK3215530T3 (da) | 2014-11-07 | 2019-11-25 | Sesen Bio Inc | Forbedrede il-6 antistoffer |
SI3227675T1 (sl) | 2014-12-03 | 2023-07-31 | Celgene Corporation | Antagonisti aktivin-actrii in uporaba za zdravljenje mielodisplastičnega sindroma |
CN108718522A (zh) | 2016-02-23 | 2018-10-30 | 赛森生物股份有限公司 | Il-6拮抗剂制剂及其用途 |
JP7145374B2 (ja) | 2016-03-18 | 2022-10-03 | ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー | インビボでの切断可能連結部分によって抗マトリプターゼ抗体にコンジュゲートされた化学療法剤を用いる腫瘍細胞の標的化 |
WO2017189963A1 (fr) * | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions pour le traitement de maladies |
CA3049967A1 (fr) * | 2017-01-06 | 2018-07-12 | The Regents Of The University Of California | Anticorps anti-ige therapeutiques et methodes et compositions associees |
JP2020532991A (ja) * | 2017-09-07 | 2020-11-19 | オーガスタ ユニバーシティ リサーチ インスティテュート,インコーポレーテッド | プログラム細胞死タンパク質1に対する抗体 |
CN114364694B (zh) * | 2019-07-12 | 2024-05-10 | 国立大学法人京都大学 | 靶向usag-1分子的用于牙齿再生治疗的中和抗体 |
CN112180099B (zh) * | 2020-09-15 | 2022-07-29 | 江南大学附属医院 | 子宫内膜异位症血清标志物的应用 |
CN115322258B (zh) * | 2022-05-31 | 2024-08-13 | 武汉真福医药股份有限公司 | 一种单克隆抗体qkma-1g41及其应用 |
CN115304677B (zh) * | 2022-06-19 | 2024-08-16 | 湖北真福医药有限公司 | 一种抗枯草芽孢杆菌纤溶酶的单克隆抗体qkma-9a10及应用 |
CN116712533B (zh) * | 2023-07-03 | 2024-02-02 | 广东暨安特博生物科技有限公司 | 一种sostdc1蛋白在制备治疗皮肤病产品中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0871705A4 (fr) * | 1995-06-05 | 2000-01-26 | Human Genome Sciences Inc | Facteur de croissance humain du type ccn |
AU2001271973A1 (en) * | 2000-07-20 | 2002-02-05 | Kevin P. Baker | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
WO2003106657A2 (fr) * | 2002-06-14 | 2003-12-24 | Stowers Institute For Medical Research | Sequences nucleotidiques et sequences d'acides amines wise/sost |
MXPA06010887A (es) * | 2004-03-23 | 2007-03-08 | Amgen Inc | Anticuerpos monoclonales especificos para ox4ol (cd 134l) humano. |
ES2666650T3 (es) * | 2006-12-29 | 2018-05-07 | OstéoQC Inc. | Métodos para alterar el crecimiento óseo mediante la administración de antagonista o agonista de sost o wise |
ES2437327T3 (es) * | 2007-06-18 | 2014-01-10 | Merck Sharp & Dohme B.V. | Anticuerpos para el receptor PD-1 humano de muerte programada |
JO3382B1 (ar) * | 2008-12-23 | 2019-03-13 | Amgen Inc | أجسام مضادة ترتبط مع مستقبل cgrp بشري |
JP2012526542A (ja) * | 2009-05-12 | 2012-11-01 | ファイザー・インク | 遮断抗dkk−1抗体およびその使用 |
-
2008
- 2008-11-21 KR KR1020107013609A patent/KR20100099193A/ko not_active Application Discontinuation
- 2008-11-21 BR BRPI0820387-3A patent/BRPI0820387A2/pt not_active IP Right Cessation
- 2008-11-21 CN CN2008801252375A patent/CN101925611A/zh active Pending
- 2008-11-21 EP EP08855691A patent/EP2220118A2/fr not_active Withdrawn
- 2008-11-21 JP JP2010534969A patent/JP5583591B2/ja not_active Expired - Fee Related
- 2008-11-21 WO PCT/US2008/012987 patent/WO2009070243A2/fr active Application Filing
- 2008-11-21 AU AU2008330125A patent/AU2008330125B2/en not_active Ceased
- 2008-11-21 MX MX2010005656A patent/MX2010005656A/es active IP Right Grant
- 2008-11-21 US US12/275,850 patent/US8043620B2/en not_active Expired - Fee Related
- 2008-11-21 CA CA2705879A patent/CA2705879A1/fr not_active Abandoned
- 2008-11-21 EA EA201000844A patent/EA201000844A1/ru unknown
-
2010
- 2010-05-05 IL IL205569A patent/IL205569A0/en unknown
- 2010-05-14 TN TN2010000213A patent/TN2010000213A1/fr unknown
- 2010-05-20 ZA ZA2010/03578A patent/ZA201003578B/en unknown
- 2010-06-15 MA MA32918A patent/MA31918B1/fr unknown
- 2010-06-21 CR CR11523A patent/CR11523A/es not_active Application Discontinuation
- 2010-06-23 CO CO10075718A patent/CO6311002A2/es not_active Application Discontinuation
-
2011
- 2011-09-15 US US13/233,983 patent/US8309092B2/en active Active
-
2014
- 2014-03-25 JP JP2014061293A patent/JP2014167002A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US8309092B2 (en) | 2012-11-13 |
TN2010000213A1 (en) | 2011-11-11 |
US20120003237A1 (en) | 2012-01-05 |
AU2008330125A1 (en) | 2009-06-04 |
EP2220118A2 (fr) | 2010-08-25 |
WO2009070243A3 (fr) | 2009-10-29 |
US8043620B2 (en) | 2011-10-25 |
JP2011504501A (ja) | 2011-02-10 |
IL205569A0 (en) | 2010-12-30 |
EA201000844A1 (ru) | 2011-10-31 |
CR11523A (es) | 2010-12-16 |
CO6311002A2 (es) | 2011-08-22 |
KR20100099193A (ko) | 2010-09-10 |
AU2008330125B2 (en) | 2012-11-22 |
CA2705879A1 (fr) | 2009-06-04 |
ZA201003578B (en) | 2011-04-28 |
US20090130114A1 (en) | 2009-05-21 |
MX2010005656A (es) | 2010-11-12 |
JP5583591B2 (ja) | 2014-09-03 |
WO2009070243A2 (fr) | 2009-06-04 |
JP2014167002A (ja) | 2014-09-11 |
CN101925611A (zh) | 2010-12-22 |
BRPI0820387A2 (pt) | 2015-05-26 |
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