JP2011500826A5 - - Google Patents
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- Publication number
- JP2011500826A5 JP2011500826A5 JP2010531215A JP2010531215A JP2011500826A5 JP 2011500826 A5 JP2011500826 A5 JP 2011500826A5 JP 2010531215 A JP2010531215 A JP 2010531215A JP 2010531215 A JP2010531215 A JP 2010531215A JP 2011500826 A5 JP2011500826 A5 JP 2011500826A5
- Authority
- JP
- Japan
- Prior art keywords
- fungicide
- alkyl
- independently
- pyrazol
- thiazolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000417 fungicide Substances 0.000 claims 93
- 230000000855 fungicidal effect Effects 0.000 claims 91
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims 40
- -1 cyano, hydroxy Chemical group 0.000 claims 32
- 229910052799 carbon Inorganic materials 0.000 claims 25
- 229910052736 halogen Inorganic materials 0.000 claims 20
- 150000002367 halogens Chemical class 0.000 claims 20
- 150000001875 compounds Chemical class 0.000 claims 17
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 16
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims 15
- 239000000203 mixture Substances 0.000 claims 14
- 125000004093 cyano group Chemical group *C#N 0.000 claims 13
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 claims 12
- 125000001424 substituent group Chemical group 0.000 claims 12
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 10
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 10
- 125000005120 alkyl cycloalkyl alkyl group Chemical group 0.000 claims 10
- 229910052739 hydrogen Inorganic materials 0.000 claims 10
- 150000003839 salts Chemical class 0.000 claims 10
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 10
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 9
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 9
- 125000004769 (C1-C4) alkylsulfonyl group Chemical group 0.000 claims 8
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 claims 8
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 claims 8
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 8
- 125000004122 cyclic group Chemical group 0.000 claims 8
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims 7
- 125000006643 (C2-C6) haloalkenyl group Chemical group 0.000 claims 7
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 7
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 7
- 125000005119 alkyl cycloalkyl group Chemical group 0.000 claims 7
- 230000003115 biocidal effect Effects 0.000 claims 7
- 229910052760 oxygen Inorganic materials 0.000 claims 7
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims 6
- 125000002619 bicyclic group Chemical group 0.000 claims 6
- 150000001721 carbon Chemical group 0.000 claims 6
- 125000004473 dialkylaminocarbonyl group Chemical group 0.000 claims 6
- 125000004768 (C1-C4) alkylsulfinyl group Chemical group 0.000 claims 5
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims 5
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 5
- 125000003545 alkoxy group Chemical group 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000004429 atom Chemical group 0.000 claims 5
- 125000004663 dialkyl amino group Chemical group 0.000 claims 5
- 125000004438 haloalkoxy group Chemical group 0.000 claims 5
- 125000005842 heteroatom Chemical group 0.000 claims 5
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 5
- 230000002401 inhibitory effect Effects 0.000 claims 5
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 5
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 claims 4
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims 4
- 125000006771 (C1-C6) haloalkylthio group Chemical group 0.000 claims 4
- 125000006650 (C2-C4) alkynyl group Chemical group 0.000 claims 4
- 125000006766 (C2-C6) alkynyloxy group Chemical group 0.000 claims 4
- 125000006765 (C2-C6) haloalkenyloxy group Chemical group 0.000 claims 4
- XTFIVUDBNACUBN-UHFFFAOYSA-N 1,3,5-trinitro-1,3,5-triazinane Chemical compound [O-][N+](=O)N1CN([N+]([O-])=O)CN([N+]([O-])=O)C1 XTFIVUDBNACUBN-UHFFFAOYSA-N 0.000 claims 4
- LUBJCRLGQSPQNN-UHFFFAOYSA-N 1-Phenylurea Chemical compound NC(=O)NC1=CC=CC=C1 LUBJCRLGQSPQNN-UHFFFAOYSA-N 0.000 claims 4
- 125000002853 C1-C4 hydroxyalkyl group Chemical group 0.000 claims 4
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 claims 4
- 125000003320 C2-C6 alkenyloxy group Chemical group 0.000 claims 4
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 claims 4
- 150000001204 N-oxides Chemical class 0.000 claims 4
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 claims 4
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 4
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 4
- 125000005640 glucopyranosyl group Chemical group 0.000 claims 4
- 125000005347 halocycloalkyl group Chemical group 0.000 claims 4
- 230000008099 melanin synthesis Effects 0.000 claims 4
- 125000001624 naphthyl group Chemical group 0.000 claims 4
- 229920006395 saturated elastomer Polymers 0.000 claims 4
- 229910052717 sulfur Inorganic materials 0.000 claims 4
- 125000004665 trialkylsilyl group Chemical group 0.000 claims 4
- 125000006767 (C2-C6) haloalkynyloxy group Chemical group 0.000 claims 3
- 125000005081 alkoxyalkoxyalkyl group Chemical group 0.000 claims 3
- 125000004858 cycloalkoxyalkyl group Chemical group 0.000 claims 3
- 125000005112 cycloalkylalkoxy group Chemical group 0.000 claims 3
- 125000005201 cycloalkylcarbonyloxy group Chemical group 0.000 claims 3
- 125000005366 cycloalkylthio group Chemical group 0.000 claims 3
- 125000001188 haloalkyl group Chemical group 0.000 claims 3
- 125000000623 heterocyclic group Chemical group 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 3
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 claims 3
- 125000005389 trialkylsiloxy group Chemical group 0.000 claims 3
- YLZGKZDEFJIHIJ-UHFFFAOYSA-N (1-methylbenzimidazol-2-yl) carbamate Chemical compound C1=CC=C2N(C)C(OC(N)=O)=NC2=C1 YLZGKZDEFJIHIJ-UHFFFAOYSA-N 0.000 claims 2
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims 2
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 claims 2
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims 2
- 125000004845 (C1-C6) alkylsulfonylamino group Chemical group 0.000 claims 2
- 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 claims 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 2
- 125000006729 (C2-C5) alkenyl group Chemical group 0.000 claims 2
- 125000006730 (C2-C5) alkynyl group Chemical group 0.000 claims 2
- 125000004757 (C2-C5) haloalkoxycarbonylamino group Chemical group 0.000 claims 2
- GVTLFGJNTIRUEG-ZHACJKMWSA-N (e)-n-(3-methoxyphenyl)-3-phenylprop-2-enamide Chemical compound COC1=CC=CC(NC(=O)\C=C\C=2C=CC=CC=2)=C1 GVTLFGJNTIRUEG-ZHACJKMWSA-N 0.000 claims 2
- OWQPOVKKUWUEKE-UHFFFAOYSA-N 1,2,3-benzotriazine Chemical compound N1=NN=CC2=CC=CC=C21 OWQPOVKKUWUEKE-UHFFFAOYSA-N 0.000 claims 2
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical compound OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 claims 2
- IRTLROCMFSDSNF-UHFFFAOYSA-N 2-phenyl-1h-pyrrole Chemical compound C1=CNC(C=2C=CC=CC=2)=C1 IRTLROCMFSDSNF-UHFFFAOYSA-N 0.000 claims 2
- YNSCKPCDFIDINW-UHFFFAOYSA-N 3-[[2-[[1-[2-(dimethylamino)acetyl]-6-methoxy-4,4-dimethyl-2,3-dihydroquinolin-7-yl]amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino]thiophene-2-carboxamide Chemical compound COC1=CC(C(CCN2C(=O)CN(C)C)(C)C)=C2C=C1NC(N=C1NC=CC1=1)=NC=1NC=1C=CSC=1C(N)=O YNSCKPCDFIDINW-UHFFFAOYSA-N 0.000 claims 2
- 125000004399 C1-C4 alkenyl group Chemical group 0.000 claims 2
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims 2
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims 2
- WLLGXSLBOPFWQV-UHFFFAOYSA-N MGK 264 Chemical compound C1=CC2CC1C1C2C(=O)N(CC(CC)CCCC)C1=O WLLGXSLBOPFWQV-UHFFFAOYSA-N 0.000 claims 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims 2
- 229930182764 Polyoxin Natural products 0.000 claims 2
- 102000005782 Squalene Monooxygenase Human genes 0.000 claims 2
- 108020003891 Squalene monooxygenase Proteins 0.000 claims 2
- GNVMUORYQLCPJZ-UHFFFAOYSA-M Thiocarbamate Chemical compound NC([S-])=O GNVMUORYQLCPJZ-UHFFFAOYSA-M 0.000 claims 2
- 102100029677 Trehalase Human genes 0.000 claims 2
- 108010087472 Trehalase Proteins 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 150000001412 amines Chemical class 0.000 claims 2
- 230000000844 anti-bacterial effect Effects 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 150000003857 carboxamides Chemical class 0.000 claims 2
- 125000000392 cycloalkenyl group Chemical group 0.000 claims 2
- 125000005167 cycloalkylaminocarbonyl group Chemical group 0.000 claims 2
- 125000005149 cycloalkylsulfinyl group Chemical group 0.000 claims 2
- 230000007123 defense Effects 0.000 claims 2
- 230000017858 demethylation Effects 0.000 claims 2
- 238000010520 demethylation reaction Methods 0.000 claims 2
- 239000000645 desinfectant Substances 0.000 claims 2
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 claims 2
- 125000004461 halocycloalkylalkyl group Chemical group 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 230000005764 inhibitory process Effects 0.000 claims 2
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 claims 2
- 229960000367 inositol Drugs 0.000 claims 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 2
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 claims 2
- XGXNTJHZPBRBHJ-UHFFFAOYSA-N n-phenylpyrimidin-2-amine Chemical compound N=1C=CC=NC=1NC1=CC=CC=C1 XGXNTJHZPBRBHJ-UHFFFAOYSA-N 0.000 claims 2
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 2
- 230000010627 oxidative phosphorylation Effects 0.000 claims 2
- PWXJULSLLONQHY-UHFFFAOYSA-N phenylcarbamic acid Chemical compound OC(=O)NC1=CC=CC=C1 PWXJULSLLONQHY-UHFFFAOYSA-N 0.000 claims 2
- 150000003904 phospholipids Chemical class 0.000 claims 2
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 claims 2
- YEBIHIICWDDQOL-YBHNRIQQSA-N polyoxin Polymers O[C@@H]1[C@H](O)[C@@H](C(C=O)N)O[C@H]1N1C(=O)NC(=O)C(C(O)=O)=C1 YEBIHIICWDDQOL-YBHNRIQQSA-N 0.000 claims 2
- FUXJMHXHGDAHPD-UHFFFAOYSA-N pyrimidine-2-carboxamide Chemical compound NC(=O)C1=NC=CC=N1 FUXJMHXHGDAHPD-UHFFFAOYSA-N 0.000 claims 2
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims 2
- 229940072172 tetracycline antibiotic Drugs 0.000 claims 2
- XLIWUFXALVTPLV-DEOSSOPVSA-N (5r)-3-[2-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-1,3-thiazol-4-yl]-5-phenyl-4h-1,2-oxazole-5-carbonitrile Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@](ON=2)(C#N)C=2C=CC=CC=2)CC1 XLIWUFXALVTPLV-DEOSSOPVSA-N 0.000 claims 1
- 125000004760 (C1-C4) alkylsulfonylamino group Chemical group 0.000 claims 1
- IAQLCKZJGNTRDO-LJQANCHMSA-N (R)-oxathiapiprolin Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@H](ON=2)C=2C(=CC=CC=2F)F)CC1 IAQLCKZJGNTRDO-LJQANCHMSA-N 0.000 claims 1
- UJOXDALUBPRYID-UHFFFAOYSA-N 1-[2-(2,5-dichlorophenyl)acetyl]piperidine-4-carbonitrile Chemical compound ClC1=CC=C(Cl)C(CC(=O)N2CCC(CC2)C#N)=C1 UJOXDALUBPRYID-UHFFFAOYSA-N 0.000 claims 1
- JCVMLKHXMOZGBT-UHFFFAOYSA-N 1-[2-(2,5-dichlorophenyl)acetyl]piperidine-4-carbothioamide Chemical compound C1CC(C(=S)N)CCN1C(=O)CC1=CC(Cl)=CC=C1Cl JCVMLKHXMOZGBT-UHFFFAOYSA-N 0.000 claims 1
- UBLNVKNVGUAFNS-UHFFFAOYSA-N 1-[2-(2,5-dimethylphenyl)acetyl]piperidine-4-carbonitrile Chemical compound CC1=CC=C(C)C(CC(=O)N2CCC(CC2)C#N)=C1 UBLNVKNVGUAFNS-UHFFFAOYSA-N 0.000 claims 1
- FZBUIMPGLLITLK-UHFFFAOYSA-N 1-[2-(2,5-dimethylphenyl)acetyl]piperidine-4-carbothioamide Chemical compound CC1=CC=C(C)C(CC(=O)N2CCC(CC2)C(N)=S)=C1 FZBUIMPGLLITLK-UHFFFAOYSA-N 0.000 claims 1
- JZWQUJDSZFLSGK-UHFFFAOYSA-N 1-[2-(2-chloro-5-methylphenyl)acetyl]piperidine-4-carbonitrile Chemical compound CC1=CC=C(Cl)C(CC(=O)N2CCC(CC2)C#N)=C1 JZWQUJDSZFLSGK-UHFFFAOYSA-N 0.000 claims 1
- DUWUGTGTLIICKB-UHFFFAOYSA-N 1-[2-(2-chloro-5-methylphenyl)acetyl]piperidine-4-carbothioamide Chemical compound CC1=CC=C(Cl)C(CC(=O)N2CCC(CC2)C(N)=S)=C1 DUWUGTGTLIICKB-UHFFFAOYSA-N 0.000 claims 1
- KLIGMAANCDCQBL-UHFFFAOYSA-N 1-[2-(3,5-dibromo-1,2,4-triazol-1-yl)acetyl]piperidine-4-carbonitrile Chemical compound N1=C(Br)N=C(Br)N1CC(=O)N1CCC(C#N)CC1 KLIGMAANCDCQBL-UHFFFAOYSA-N 0.000 claims 1
- JBCKNQPTGKBBQZ-UHFFFAOYSA-N 1-[2-(3,5-dibromo-1,2,4-triazol-1-yl)acetyl]piperidine-4-carbothioamide Chemical compound C1CC(C(=S)N)CCN1C(=O)CN1C(Br)=NC(Br)=N1 JBCKNQPTGKBBQZ-UHFFFAOYSA-N 0.000 claims 1
- UTWIPBLXZDPNHW-UHFFFAOYSA-N 1-[2-(3,5-dichloro-1,2,4-triazol-1-yl)acetyl]piperidine-4-carbonitrile Chemical compound N1=C(Cl)N=C(Cl)N1CC(=O)N1CCC(C#N)CC1 UTWIPBLXZDPNHW-UHFFFAOYSA-N 0.000 claims 1
- QLPICFWIQTVCSX-UHFFFAOYSA-N 1-[2-(3,5-dichloro-1,2,4-triazol-1-yl)acetyl]piperidine-4-carbothioamide Chemical compound C1CC(C(=S)N)CCN1C(=O)CN1C(Cl)=NC(Cl)=N1 QLPICFWIQTVCSX-UHFFFAOYSA-N 0.000 claims 1
- GGRMDSCNMJFSJF-UHFFFAOYSA-N 1-[2-(5-chloro-2-methylphenyl)acetyl]piperidine-4-carbonitrile Chemical compound CC1=CC=C(Cl)C=C1CC(=O)N1CCC(C#N)CC1 GGRMDSCNMJFSJF-UHFFFAOYSA-N 0.000 claims 1
- ISDKKTJZLBJJMK-UHFFFAOYSA-N 1-[2-(5-chloro-2-methylphenyl)acetyl]piperidine-4-carbothioamide Chemical compound CC1=CC=C(Cl)C=C1CC(=O)N1CCC(C(N)=S)CC1 ISDKKTJZLBJJMK-UHFFFAOYSA-N 0.000 claims 1
- QWZOUWNYDSVFLX-LJQANCHMSA-N 1-[4-[4-[(5r)-5-(2,6-dichlorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@H](ON=2)C=2C(=CC=CC=2Cl)Cl)CC1 QWZOUWNYDSVFLX-LJQANCHMSA-N 0.000 claims 1
- WYJLXVYJJNODRE-HXUWFJFHSA-N 1-[4-[4-[(5r)-5-(2-chlorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@H](ON=2)C=2C(=CC=CC=2)Cl)CC1 WYJLXVYJJNODRE-HXUWFJFHSA-N 0.000 claims 1
- HFSOCJMWHBUPMW-HXUWFJFHSA-N 1-[4-[4-[(5r)-5-(2-fluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@H](ON=2)C=2C(=CC=CC=2)F)CC1 HFSOCJMWHBUPMW-HXUWFJFHSA-N 0.000 claims 1
- FACIKTWBHFNWON-OAQYLSRUSA-N 1-[4-[4-[(5r)-5-(2-methylphenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@H](ON=2)C=2C(=CC=CC=2)C)CC1 FACIKTWBHFNWON-OAQYLSRUSA-N 0.000 claims 1
- HFGIAJCHFQMGKC-XMMPIXPASA-N 1-[4-[4-[(5r)-5-methyl-5-phenyl-4h-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@](C)(ON=2)C=2C=CC=CC=2)CC1 HFGIAJCHFQMGKC-XMMPIXPASA-N 0.000 claims 1
- CPRYNZKZNUYGMT-XMMPIXPASA-N 1-acetyl-3-[(5r)-3-[2-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl]benzimidazol-2-one Chemical compound C([C@@H](ON=1)N2C3=CC=CC=C3N(C2=O)C(=O)C)C=1C(N=1)=CSC=1C(CC1)CCN1C(=O)CN1N=C(C(F)(F)F)C=C1C CPRYNZKZNUYGMT-XMMPIXPASA-N 0.000 claims 1
- BISSWIGAZBBUHT-HSZRJFAPSA-N 1-methyl-3-[(5r)-3-[2-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl]benzimidazol-2-one Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@H](ON=2)N2C(N(C)C3=CC=CC=C32)=O)CC1 BISSWIGAZBBUHT-HSZRJFAPSA-N 0.000 claims 1
- 125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 claims 1
- KUEAZWHHFFDLNY-OAQYLSRUSA-N 2-[(5r)-3-[2-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl]benzonitrile Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@H](ON=2)C=2C(=CC=CC=2)C#N)CC1 KUEAZWHHFFDLNY-OAQYLSRUSA-N 0.000 claims 1
- YTRDDCWWIVWDDL-XMMPIXPASA-N 2-[3,5-bis(trifluoromethyl)pyrazol-1-yl]-1-[4-[4-[(3r)-spiro[1,2-dihydroindene-3,5'-4h-1,2-oxazole]-3'-yl]-1,3-thiazol-2-yl]piperidin-1-yl]ethanone Chemical compound N1=C(C(F)(F)F)C=C(C(F)(F)F)N1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@]3(C4=CC=CC=C4CC3)ON=2)CC1 YTRDDCWWIVWDDL-XMMPIXPASA-N 0.000 claims 1
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- SVPPIKFSUCOVHQ-UHFFFAOYSA-N 2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-1-[4-[4-(5-phenyl-1,2-oxazol-3-yl)-1,3-thiazol-2-yl]piperidin-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C2=NOC(=C2)C=2C=CC=CC=2)CC1 SVPPIKFSUCOVHQ-UHFFFAOYSA-N 0.000 claims 1
- VRFDJVDIZBADRD-JOCHJYFZSA-N 2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-1-[4-[4-[(5r)-5-(2,4,6-trimethoxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]ethanone Chemical compound COC1=CC(OC)=CC(OC)=C1[C@@H]1ON=C(C=2N=C(SC=2)C2CCN(CC2)C(=O)CN2C(=CC(=N2)C(F)(F)F)C)C1 VRFDJVDIZBADRD-JOCHJYFZSA-N 0.000 claims 1
- CLRPPJBUFODHQQ-JOCHJYFZSA-N 2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-1-[4-[4-[(5r)-5-(2,4,6-trimethylphenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2C[C@@H](ON=2)C=2C(=CC(C)=CC=2C)C)CC1 CLRPPJBUFODHQQ-JOCHJYFZSA-N 0.000 claims 1
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| US9090604B2 (en) | 2006-07-27 | 2015-07-28 | E I Du Pont De Nemours And Company | Fungicidal azocyclic amides |
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| MX2010008102A (es) | 2008-01-25 | 2010-08-04 | Du Pont | Compuestos fungicidas heterociclicos. |
| CN101925598B (zh) * | 2008-01-25 | 2014-03-05 | 杜邦公司 | 杀真菌酰胺 |
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| US9540322B2 (en) | 2008-08-18 | 2017-01-10 | Yale University | MIF modulators |
| US9643922B2 (en) | 2008-08-18 | 2017-05-09 | Yale University | MIF modulators |
| EP2326631A4 (en) * | 2008-08-18 | 2012-03-21 | Univ Yale | MIF MODULATORS |
| BRPI0920767B1 (pt) | 2008-10-01 | 2018-07-17 | Bayer Intellectual Property Gmbh | tiazóis substituídos por heterociclila como agentes protetores de cultura, seus usos e seus processos de preparação, composições e seu processo de preparação, e método para combate a fungos nocivos fitopatogênicos |
| ES2452299T3 (es) | 2008-12-02 | 2014-03-31 | E. I. Du Pont De Nemours And Company | Compuestos heterocíclicos fungicidas |
| CN102292334A (zh) * | 2008-12-11 | 2011-12-21 | 拜尔农作物科学股份公司 | 噻唑基肟醚和腙植物保护剂 |
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| US8927551B2 (en) | 2009-05-18 | 2015-01-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US8765735B2 (en) | 2009-05-18 | 2014-07-01 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| AR076697A1 (es) * | 2009-05-25 | 2011-06-29 | Sumitomo Chemical Co | Composicion y metodo para controlar enfermedades de plantas |
| BRPI1008143A2 (pt) * | 2009-06-05 | 2015-08-25 | Basf Se | Mistura composição agroquimica metodo para o combatre de fungos novicios fitopatogenicos e material de propagação de planta |
| EP2272846A1 (de) | 2009-06-23 | 2011-01-12 | Bayer CropScience AG | Thiazolylpiperidin Derivate als Fungizide |
| JP5584532B2 (ja) * | 2009-07-06 | 2014-09-03 | 石原産業株式会社 | 農園芸用殺菌剤組成物及び植物病害の防除方法 |
| UA107938C2 (en) | 2009-08-12 | 2015-03-10 | Syngenta Participations Ag | Heterocycles with microbicidal properties |
| US8557821B2 (en) | 2009-08-12 | 2013-10-15 | Syngenta Crop Protection, Llc | Microbiocidal heterocycles |
| KR20120101019A (ko) | 2009-10-30 | 2012-09-12 | 바이엘 크롭사이언스 아게 | 헤테로아릴피페리딘 및 -피페라진 유도체 |
| WO2011076699A1 (de) | 2009-12-21 | 2011-06-30 | Bayer Cropscience Ag | Bis(difluormethyl)pyrazole als fungizide |
| US8629286B2 (en) | 2009-12-22 | 2014-01-14 | Syngenta Crop Protection, Llc | Pyrazole derivatives |
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| KR20130100903A (ko) | 2010-04-28 | 2013-09-12 | 바이엘 크롭사이언스 아게 | 살진균제로서의 케토헤테로아릴피페리딘 및 케토헤테로아릴피페라진 유도체 |
| US8815775B2 (en) | 2010-05-18 | 2014-08-26 | Bayer Cropscience Ag | Bis(difluoromethyl)pyrazoles as fungicides |
| US8722678B2 (en) * | 2010-05-20 | 2014-05-13 | E I Du Pont De Nemours And Company | Fungicidal oximes and hydrazones |
| ES2660611T3 (es) | 2010-05-27 | 2018-03-23 | Bayer Cropscience Ag | Derivados de ácido piridinilcarboxílico como fungicidas |
| AU2015205864B2 (en) * | 2010-08-11 | 2016-04-21 | Bayer Intellectual Property Gmbh | Heteroarylpiperidine and -piperazine derivatives as fungicides |
| US20120122928A1 (en) * | 2010-08-11 | 2012-05-17 | Bayer Cropscience Ag | Heteroarylpiperidine and -Piperazine Derivatives as Fungicides |
| US8759527B2 (en) * | 2010-08-25 | 2014-06-24 | Bayer Cropscience Ag | Heteroarylpiperidine and -piperazine derivatives as fungicides |
| EP2423210A1 (de) | 2010-08-25 | 2012-02-29 | Bayer CropScience AG | Heteroarylpiperidin- und -piperazinderivate als Fungizide |
| CN103338638B (zh) * | 2010-10-07 | 2016-04-06 | 拜尔农科股份公司 | 包含四唑基肟衍生物和噻唑基哌啶衍生物的杀真菌剂组合物 |
| CN103492379B (zh) * | 2010-10-27 | 2018-06-15 | 拜耳知识产权有限责任公司 | 作为杀真菌剂的杂芳基哌啶和杂芳基哌嗪衍生物 |
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| JP2013545804A (ja) * | 2010-12-16 | 2013-12-26 | ダウ アグロサイエンシィズ エルエルシー | アミノピリミジンとその他の殺真菌剤との相乗的殺真菌性相互作用 |
| BR112013015166A2 (pt) * | 2010-12-17 | 2016-07-12 | Du Pont | composto selecionado a partir de fórmula 1, composição fungicida e método para controlar doenças de plantas |
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| KR101848116B1 (ko) * | 2011-02-01 | 2018-04-11 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 살진균제로서의 헤테로아릴 피페리딘 및 헤테로아릴 피페라진 유도체 |
| US8748432B2 (en) | 2011-02-10 | 2014-06-10 | Syngenta Participations Ag | Microbiocidal pyrazole derivatives |
| US20130317064A1 (en) | 2011-02-10 | 2013-11-28 | Syngenta Participations Ag | Microbiocidal pyrazole derivatives |
| UA112539C2 (uk) | 2011-03-03 | 2016-09-26 | Новартіс Аг | Спосіб одержання похідних 2-карбоксамідциклоаміносечовини |
| EP2532233A1 (en) | 2011-06-07 | 2012-12-12 | Bayer CropScience AG | Active compound combinations |
| CN102318627A (zh) * | 2011-06-26 | 2012-01-18 | 青岛奥迪斯生物科技有限公司 | 一种创新型的高效杀菌组合物 |
| CN102308832A (zh) * | 2011-06-26 | 2012-01-11 | 青岛奥迪斯生物科技有限公司 | 一种新型环保的杀菌组合物 |
| US10004232B2 (en) | 2011-09-15 | 2018-06-26 | Bayer Intellectual Property Gmbh | Piperidine pyrazoles as fungicides |
| CN102993100B (zh) * | 2011-09-19 | 2014-10-22 | 中国中化股份有限公司 | 取代吡唑(硫)酮类化合物及其用途 |
| CN103889980A (zh) | 2011-10-18 | 2014-06-25 | 先正达参股股份有限公司 | 杀微生物的吡唑衍生物 |
| CN103889982A (zh) | 2011-10-18 | 2014-06-25 | 先正达参股股份有限公司 | 杀微生物的吡唑衍生物 |
| EP2921491B1 (de) * | 2011-12-27 | 2017-08-16 | Bayer Intellectual Property GmbH | Zwischenverbindungen zur herstellung von heteroarylpiperidinen und -piperazinderivaten als fungizide |
| AU2013216354B2 (en) * | 2012-02-02 | 2017-08-31 | Idorsia Pharmaceuticals Ltd | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives |
| PE20190342A1 (es) * | 2012-02-27 | 2019-03-07 | Bayer Ip Gmbh | Combinaciones de compuestos activos |
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| EP2820015A1 (en) | 2012-03-02 | 2015-01-07 | Syngenta Participations AG | Microbiocidal pyrazole derivatives |
| ES2588386T3 (es) | 2012-08-30 | 2016-11-02 | Bayer Cropscience Ag | Procedimiento de descarboxilación de derivados de ácido 3,5-bis(haloalquil)-pirazol-4-carboxílico |
| WO2014060176A1 (en) | 2012-10-16 | 2014-04-24 | Syngenta Participations Ag | Microbiocidal pyrazole derivatives |
| CN102977052B (zh) * | 2012-12-19 | 2014-08-13 | 河南省新乡市农业科学院 | 2-巯基苯并噻唑锰锌及其制备方法、应用 |
| WO2014095994A1 (en) | 2012-12-20 | 2014-06-26 | Basf Se | Compositions comprising a triazole compound |
| DK3219707T3 (da) | 2013-01-09 | 2019-09-23 | Basf Agro Bv | Fremgangsmåde til fremstilling af substituerede oxiraner og triazoler |
| WO2014118142A1 (en) | 2013-02-01 | 2014-08-07 | Syngenta Participations Ag | Microbiocidal pyrazole derivatives |
| WO2014118143A1 (en) | 2013-02-04 | 2014-08-07 | Syngenta Participations Ag | Microbiocidal pyrazole derivatives |
| CN105143214B (zh) * | 2013-02-15 | 2018-04-03 | 孟山都技术公司 | 用于控制线虫害虫的3,5‑二取代的‑4,5‑二氢‑1,2,4‑噁二唑 |
| WO2014154530A1 (en) | 2013-03-25 | 2014-10-02 | Syngenta Participations Ag | Microbiocidal pyrazole derivatives |
| EP2801575A1 (en) | 2013-05-07 | 2014-11-12 | Bayer CropScience AG | Heteroaryldihydropyridine derivatives as fungicides |
| TWI632142B (zh) * | 2013-06-24 | 2018-08-11 | 德商拜耳作物科學股份有限公司 | 作為殺真菌劑之六氫吡啶羧酸衍生物 |
| RU2669997C2 (ru) | 2013-07-08 | 2018-10-17 | Басф Агро Б.В. | Композиции, содержащие триазольное соединение и биопестицид |
| US9771357B2 (en) | 2013-07-09 | 2017-09-26 | Ono Pharmaceutical Co., Ltd. | ALXR agonist compound |
| CN105658649B (zh) | 2013-07-22 | 2019-03-22 | 爱杜西亚药品有限公司 | 1-(哌嗪-1-基)-2-([1,2,4]三唑-1-基)-乙酮衍生物 |
| CN104336040A (zh) * | 2013-07-31 | 2015-02-11 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮的高效杀菌组合物 |
| CN104336033A (zh) * | 2013-08-01 | 2015-02-11 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮与硫代氨基甲酸酯类的杀菌组合物 |
| CN104336079A (zh) * | 2013-08-01 | 2015-02-11 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮的复配杀菌组合物 |
| CN104336024A (zh) * | 2013-08-08 | 2015-02-11 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮与酰胺类的杀菌组合物 |
| CN104336048A (zh) * | 2013-08-08 | 2015-02-11 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮与三唑类的杀菌组合物 |
| CN104336023A (zh) * | 2013-08-08 | 2015-02-11 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮的杀菌组合物 |
| CN104336038A (zh) * | 2013-08-08 | 2015-02-11 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮的复配杀菌组合物 |
| CN104336027B (zh) * | 2013-08-09 | 2018-07-10 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮的农药组合物 |
| WO2015028457A1 (en) * | 2013-08-28 | 2015-03-05 | Bayer Cropscience Ag | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides |
| MX361771B (es) * | 2013-10-17 | 2018-12-17 | Bayer Cropscience Ag | Forma cristalina novedosa de 2-{3-[2-(1-{[3,5-bis(difluorometil)-1 h-pirazol-1-il]acetil}piperidin-4-il)-1,3-tiazol-4-il]-4,5-dihidr o-1,2-oxazol-5-il}-3-clorofenilmetanosulfonato. |
| CN107125248A (zh) * | 2013-11-19 | 2017-09-05 | 陕西汤普森生物科技有限公司 | 一种含氟噻唑吡乙酮的高效杀菌组合物 |
| CN104642360A (zh) * | 2013-11-19 | 2015-05-27 | 陕西汤普森生物科技有限公司 | 一种含氟噻唑吡乙酮和甲氧基丙烯酸酯类的杀菌组合物 |
| WO2015140071A1 (en) * | 2014-03-18 | 2015-09-24 | Bayer Cropscience Ag | Active compound combinations |
| ES2681286T3 (es) | 2014-03-24 | 2018-09-12 | Bayer Cropscience Aktiengesellschaft | Derivados de fenilpiperidincarboxamida como fungicidas |
| AR099789A1 (es) | 2014-03-24 | 2016-08-17 | Actelion Pharmaceuticals Ltd | Derivados de 8-(piperazin-1-il)-1,2,3,4-tetrahidro-isoquinolina |
| MX382659B (es) * | 2014-05-28 | 2025-03-11 | Bayer Cropscience Ag | Proceso para la preparación de derivados de tiazol. |
| WO2015189114A1 (en) | 2014-06-11 | 2015-12-17 | Bayer Cropscience Ag | Process for preparing 3-chloro-2-vinylphenol |
| KR102430612B1 (ko) | 2014-06-11 | 2022-08-08 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 피페리딘-4-카보티오아미드의 제조 |
| BR112016030116B1 (pt) | 2014-06-25 | 2021-07-06 | BASF Agro B.V. | composições, uso de uma composição, método para o combate dos fungos e material de propagação dos vegetais |
| WO2016024350A1 (ja) | 2014-08-13 | 2016-02-18 | 株式会社エス・ディー・エス バイオテック | 縮合１１員環化合物及びそれらを含有する農園芸用殺菌剤 |
| AU2015342067B2 (en) | 2014-11-07 | 2019-10-31 | Basf Se | Pesticidal mixtures |
| AR103399A1 (es) | 2015-01-15 | 2017-05-10 | Actelion Pharmaceuticals Ltd | Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3 |
| MY187614A (en) | 2015-01-15 | 2021-10-04 | Idorsia Pharmaceuticals Ltd | Hydroxyalkyl-piperazine derivatives as cxcr3 receptor modulators |
| EP3265444B1 (en) | 2015-03-05 | 2018-12-26 | Bayer CropScience Aktiengesellschaft | Process for preparing piperidine-4-carbothioamide hydrochloride |
| JPWO2016194971A1 (ja) * | 2015-06-01 | 2018-03-15 | 石原産業株式会社 | 殺菌剤組成物及び植物病害の防除方法 |
| WO2016202761A1 (en) | 2015-06-17 | 2016-12-22 | Bayer Cropscience Aktiengesellschaft | Active compound combinations |
| CN105154102A (zh) * | 2015-09-07 | 2015-12-16 | 龚灿锋 | 一种农林土壤修复杀虫剂 |
| CN105052945A (zh) * | 2015-09-09 | 2015-11-18 | 江苏省绿盾植保农药实验有限公司 | 一种含有氟吡菌胺和氟噻唑吡乙酮的杀菌剂组合物 |
| BR112018011061B1 (pt) * | 2015-12-01 | 2022-06-14 | Sumitomo Chemical Company, Limited | Composição para controle de doenças em plantas e método para controle de doenças em plantas |
| CN105541830B (zh) * | 2015-12-14 | 2018-04-27 | 北京迪尔乐农业高新技术研发中心 | 一种杀菌化合物、制备方法及其应用 |
| CN108602765B (zh) | 2016-02-08 | 2022-05-03 | 高文有限公司 | 1,2-苯二甲醇化合物的制造方法 |
| CN108601353B (zh) | 2016-02-08 | 2024-04-05 | 高文作物保护公司 | 杀菌性组合物 |
| WO2017157916A1 (en) | 2016-03-16 | 2017-09-21 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on soybean |
| WO2017157910A1 (en) | 2016-03-16 | 2017-09-21 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on cereals |
| EP3429358A1 (en) | 2016-03-16 | 2019-01-23 | Basf Se | Use of tetrazolinones for combating resistant phytopathogenic fungi on fruits |
| CN106070241A (zh) * | 2016-06-21 | 2016-11-09 | 广东中迅农科股份有限公司 | 一种含有二氯恶菌唑和氟噻唑吡乙酮的杀菌组合物 |
| CN106212477A (zh) * | 2016-07-22 | 2016-12-14 | 深圳诺普信农化股份有限公司 | 杀菌组合物及其应用 |
| CN105941426B (zh) * | 2016-07-25 | 2018-11-02 | 泉州市诗展文化发展有限公司 | 一种含氟噻唑吡乙酮和琥胶肥酸铜的农药组合物 |
| CN106172433A (zh) * | 2016-07-25 | 2016-12-07 | 李祥英 | 一种含氟噻唑吡乙酮和氨基寡糖素的农药组合物 |
| CN106035346A (zh) * | 2016-08-02 | 2016-10-26 | 李祥英 | 一种含氟噻唑吡乙酮和乙蒜素的杀菌组合物 |
| CN106234377B (zh) * | 2016-08-03 | 2018-10-09 | 陈军明 | 一种含氟噻唑吡乙酮和丁子香酚的复配组合物 |
| CN106212476A (zh) * | 2016-08-03 | 2016-12-14 | 田文华 | 一种含氟噻唑吡乙酮和松脂酸铜的杀菌组合物 |
| CN106234389B (zh) * | 2016-08-03 | 2018-10-12 | 陈军明 | 一种含氟噻唑吡乙酮和小檗碱的农药组合物 |
| CN106305741A (zh) * | 2016-08-15 | 2017-01-11 | 青岛瀚生生物科技股份有限公司 | 农用复配杀菌剂及其应用 |
| CN107751213A (zh) * | 2016-08-17 | 2018-03-06 | 浙江中山化工集团股份有限公司 | 一种杀菌农药组合物 |
| CN108522519A (zh) * | 2017-03-02 | 2018-09-14 | 江苏龙灯化学有限公司 | 一种杀菌组合物 |
| CN106937637A (zh) * | 2017-04-22 | 2017-07-11 | 北京科发伟业农药技术中心 | 含氟烯线砜的组合物 |
| CN111362933A (zh) * | 2017-05-16 | 2020-07-03 | 南开大学 | 一种α-氨基丙烯酸类杀微生物剂及其制备方法和用途 |
| CN109221163A (zh) * | 2017-07-10 | 2019-01-18 | 江苏龙灯化学有限公司 | 一种杀菌组合物 |
| US11304380B2 (en) | 2017-07-20 | 2022-04-19 | Brett Evan Patrick | Method and apparatus for airborne dissemination and implantation of seeds |
| CN109380240B (zh) * | 2017-08-03 | 2020-12-08 | 沈阳中化农药化工研发有限公司 | 一种含有氟噻唑吡乙酮的农药组合物及其应用 |
| CN109380241A (zh) * | 2017-08-07 | 2019-02-26 | 江苏龙灯化学有限公司 | 一种杀菌组合物 |
| WO2019048989A1 (en) * | 2017-09-08 | 2019-03-14 | Pi Industries Ltd. | NOVEL FUNGICIDE HETEROCYCLIC COMPOUNDS |
| CN109691453A (zh) * | 2017-10-24 | 2019-04-30 | 佛山市盈辉作物科学有限公司 | 含有丙硫菌唑、异噻菌胺、氟噻唑吡乙酮的复配悬浮种衣剂 |
| CN109691455A (zh) * | 2017-10-24 | 2019-04-30 | 佛山市盈辉作物科学有限公司 | 含有噻菌灵、咯菌腈、氟噻唑吡乙酮的复配种子处理剂 |
| CN109699655A (zh) * | 2017-10-26 | 2019-05-03 | 佛山市盈辉作物科学有限公司 | 一种含氟噻唑吡乙酮和噻霉酮的农药组合物 |
| CN109699654A (zh) * | 2017-10-26 | 2019-05-03 | 佛山市盈辉作物科学有限公司 | 一种含氟噻唑吡乙酮和申嗪霉素的农药组合物 |
| CN109717194A (zh) * | 2017-10-31 | 2019-05-07 | 江苏龙灯化学有限公司 | 一种杀菌组合物 |
| CN107950543A (zh) * | 2017-12-10 | 2018-04-24 | 广东中迅农科股份有限公司 | 一种含有噻霉酮和氟噻唑吡乙酮的杀菌组合物 |
| CN108184866A (zh) * | 2018-01-16 | 2018-06-22 | 安徽省农业科学院植物保护与农产品质量安全研究所 | 一种含氟噻唑吡乙酮和粉唑醇的杀菌组合物 |
| CN108174857A (zh) * | 2018-02-02 | 2018-06-19 | 深圳诺普信农化股份有限公司 | 一种杀菌组合物及其应用 |
| CN108294017A (zh) * | 2018-02-08 | 2018-07-20 | 河北赛丰生物科技有限公司 | 一种含氟噻唑吡乙酮的杀菌剂组合物及其应用 |
| CN108402055A (zh) * | 2018-02-08 | 2018-08-17 | 河北赛丰生物科技有限公司 | 一种杀菌组合物及其应用 |
| CN108207969A (zh) * | 2018-02-08 | 2018-06-29 | 河北赛丰生物科技有限公司 | 一种杀菌剂组合物及其应用 |
| CN108142424A (zh) * | 2018-02-11 | 2018-06-12 | 河北省农林科学院植物保护研究所 | 一种氟噻唑吡乙酮和咯菌腈的杀菌组合物与制剂及其应用 |
| CN110818708B (zh) * | 2018-08-14 | 2022-04-01 | 华中师范大学 | 含稠杂环结构的化合物及其制备方法和应用以及杀菌剂 |
| CN111848612B (zh) * | 2019-07-31 | 2021-09-14 | 华中师范大学 | 含稠杂环结构的化合物及其制备方法和应用以及杀菌剂 |
| CN110879209A (zh) * | 2019-12-09 | 2020-03-13 | 济南大学 | 一种γ-氨基丁酸的快速检测方法 |
| CN111357751A (zh) * | 2020-04-24 | 2020-07-03 | 青岛科技大学 | 一种含氟噻唑吡乙酮和丙氧喹啉的杀菌组合物 |
| CN111357746A (zh) * | 2020-04-24 | 2020-07-03 | 青岛科技大学 | 一种含氟噻唑吡乙酮和苯氧喹啉的杀菌组合物 |
| CN111387185A (zh) * | 2020-05-08 | 2020-07-10 | 兰州大学 | 一种萘替芬类似物在防治农业植物病害中的用途 |
| CN111587889A (zh) * | 2020-07-01 | 2020-08-28 | 安徽省农业科学院植物保护与农产品质量安全研究所 | 一种含氟噻唑吡乙酮和萎锈灵的杀菌组合物 |
| TW202236965A (zh) | 2020-12-15 | 2022-10-01 | 印度商皮埃企業有限公司 | 包含哌啶噻唑化合物之新穎農業化學組成物 |
| UY39763A (es) | 2021-05-15 | 2022-11-30 | Pi Industries Ltd | Composición agroquímica novedosa que comprende compuestos de piperidin-tiazol |
| CN115594670B (zh) * | 2021-06-28 | 2025-07-04 | 浙江省化工研究院有限公司 | 一类含三氟甲基噁二唑类衍生物、其制备方法及应用 |
| US20240368187A1 (en) * | 2021-07-12 | 2024-11-07 | Toyobo Co., Ltd. | Method for producing aromatic dihalogen compound |
| CN113444108B (zh) * | 2021-07-19 | 2022-03-25 | 成都大学 | 含二氢苯并呋喃结构的1,4-硫桥多环化合物、其制备方法及用途 |
| CN116199683A (zh) * | 2021-11-30 | 2023-06-02 | 江苏中旗科技股份有限公司 | 一种含有噁二唑结构的化合物及其制备方法和应用以及一种杀菌剂 |
| CN114213352B (zh) * | 2021-12-09 | 2023-05-05 | 苏州汉德创宏生化科技有限公司 | 一种1-氧代-1-(2-氧代恶唑烷-3-基)丙-2-基4-甲基苯磺酸酯的制备方法 |
| CN114651825A (zh) * | 2022-03-01 | 2022-06-24 | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | 一种基于分子抗病途径的澳洲坚果茎溃疡病抑制剂 |
| CN117624158A (zh) * | 2022-08-26 | 2024-03-01 | 江苏中旗科技股份有限公司 | 含链状羧酸酰胺结构的化合物及其制备方法和应用、杀菌剂 |
| CN118235770B (zh) * | 2022-09-30 | 2025-08-29 | 青岛海利尔生物科技有限公司 | 一种含fluoxapiprolin的杀菌组合物及其应用 |
| EP4611544A2 (en) * | 2022-11-02 | 2025-09-10 | Syngenta Crop Protection AG | Method of controlling, limiting or preventing oomycetes |
| CN116195591B (zh) * | 2023-02-07 | 2024-04-30 | 广西壮族自治区农业科学院 | 一种防治瓜类蔓枯病的杀菌剂组合物 |
| CN119453223B (zh) * | 2023-03-06 | 2025-09-30 | 青岛滕润翔检测评价有限公司 | 一种杀菌组合物及其应用 |
| CN120660706A (zh) * | 2023-07-13 | 2025-09-19 | 北京辉胜农业科技有限公司 | 一种防治马铃薯晚疫病的农药组合物 |
| EP4509511A1 (en) | 2023-08-17 | 2025-02-19 | Bayer Aktiengesellschaft | Substituted spiro-isoxazolinyl lactams, salts thereof and their use as herbicidally active substances |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5001115A (en) * | 1989-05-17 | 1991-03-19 | University Of Florida | Prodrugs of biologically active hydroxyaromatic compounds |
| GB9000130D0 (en) * | 1990-01-04 | 1990-03-07 | Ici Plc | Fungicides |
| DE4309272A1 (de) * | 1993-03-23 | 1994-09-29 | Basf Ag | Fungizide Mischung |
| AU1596101A (en) | 1999-11-12 | 2001-06-06 | Merck & Co., Inc. | Aliphatic amine substituted piperidyl diaryl pyrrole derivatives as antiprotozoal agents |
| ES2294172T3 (es) * | 2001-10-22 | 2008-04-01 | Daiichi Sankyo Company, Limited | Procedimiento para cribar un medicamento que actua sobre la pared celular. |
| GB0230162D0 (en) | 2002-12-24 | 2003-02-05 | Metris Therapeutics Ltd | Compounds useful in inhibiting angiogenesis |
| FR2856685B1 (fr) | 2003-06-25 | 2005-09-23 | Merck Sante Sas | Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2865733B1 (fr) | 2004-02-04 | 2007-10-12 | Merck Sante Sas | Derives de thiazolylimidazole, leurs procedes de preparation, les compositions pharmaceutiques qui les contiennent et leurs applications en medecine |
| US20080004263A1 (en) | 2004-03-04 | 2008-01-03 | Santora Vincent J | Ligands of Follicle Stimulating Hormone Receptor and Methods of Use Thereof |
| CA2564139A1 (en) | 2004-04-13 | 2005-12-08 | Arena Pharmaceuticals, Inc. | Modulators of human g protein-coupled receptors for the treatment of hyperglycemia and related disorders |
| WO2005115336A2 (en) * | 2004-05-15 | 2005-12-08 | Collegium Pharmaceutical, Inc. | Sprayable formulations for the treatment of acute inflammatory skin conditions |
| CN101084211A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为治疗剂的用途 |
| WO2006032322A1 (en) | 2004-09-20 | 2006-03-30 | 4Sc Ag | NOVEL HETEROCYCLIC NF-κB INHIBITORS |
| TW200633990A (en) | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
| US7754724B2 (en) * | 2005-06-30 | 2010-07-13 | Dow Agrosciences Llc | N-substituted piperazines |
| TW200738701A (en) * | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
| CN1331855C (zh) * | 2005-11-03 | 2007-08-15 | 上海人类基因组研究中心 | 一种抗真菌化合物在制药中的应用 |
| WO2007064553A2 (en) | 2005-11-29 | 2007-06-07 | Merck & Co., Inc. | Thiazole derivatives as cxcr3 receptor modulators |
| WO2007070433A2 (en) | 2005-12-12 | 2007-06-21 | Merck & Co., Inc. | 2-arylthiazole derivatives as cxcr3 receptor modulators |
| WO2008013622A2 (en) * | 2006-07-27 | 2008-01-31 | E. I. Du Pont De Nemours And Company | Fungicidal azocyclic amides |
| WO2008091594A2 (en) | 2007-01-24 | 2008-07-31 | E. I. Du Pont De Nemours And Company | Fungicidal mixtures |
| JP5337711B2 (ja) * | 2007-01-25 | 2013-11-06 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 殺菌性アミド |
| CN101925598B (zh) * | 2008-01-25 | 2014-03-05 | 杜邦公司 | 杀真菌酰胺 |
| BRPI0920767B1 (pt) * | 2008-10-01 | 2018-07-17 | Bayer Intellectual Property Gmbh | tiazóis substituídos por heterociclila como agentes protetores de cultura, seus usos e seus processos de preparação, composições e seu processo de preparação, e método para combate a fungos nocivos fitopatogênicos |
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