JP2011500562A5 - - Google Patents
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- Publication number
- JP2011500562A5 JP2011500562A5 JP2010528867A JP2010528867A JP2011500562A5 JP 2011500562 A5 JP2011500562 A5 JP 2011500562A5 JP 2010528867 A JP2010528867 A JP 2010528867A JP 2010528867 A JP2010528867 A JP 2010528867A JP 2011500562 A5 JP2011500562 A5 JP 2011500562A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkenyl
- compound according
- compound
- ring members
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*1C=C(*)C(C)(C)CC1 Chemical compound C*1C=C(*)C(C)(C)CC1 0.000 description 3
- ZRVYMRHQWZKLKY-UHFFFAOYSA-N CC1(COC)CCCC1 Chemical compound CC1(COC)CCCC1 ZRVYMRHQWZKLKY-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99878607P | 2007-10-10 | 2007-10-10 | |
| US60/998,786 | 2007-10-10 | ||
| US6872408P | 2008-03-06 | 2008-03-06 | |
| US61/068,724 | 2008-03-06 | ||
| PCT/US2008/011422 WO2009048527A1 (en) | 2007-10-10 | 2008-10-03 | Substituted biphenyl gpr40 modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500562A JP2011500562A (ja) | 2011-01-06 |
| JP2011500562A5 true JP2011500562A5 (https=) | 2011-11-17 |
| JP5591706B2 JP5591706B2 (ja) | 2014-09-17 |
Family
ID=40338063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528867A Expired - Fee Related JP5591706B2 (ja) | 2007-10-10 | 2008-10-03 | 置換ビフェニルｇｐｒ４０調節因子 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8030354B2 (https=) |
| EP (1) | EP2205548A1 (https=) |
| JP (1) | JP5591706B2 (https=) |
| KR (1) | KR20100090249A (https=) |
| CN (1) | CN102083783A (https=) |
| AR (1) | AR068840A1 (https=) |
| AU (1) | AU2008311355B2 (https=) |
| BR (1) | BRPI0818253A2 (https=) |
| CA (1) | CA2702047C (https=) |
| CL (1) | CL2008002997A1 (https=) |
| CO (1) | CO6270312A2 (https=) |
| CR (1) | CR11420A (https=) |
| IL (1) | IL204635A0 (https=) |
| MA (1) | MA31841B1 (https=) |
| MX (1) | MX2010003876A (https=) |
| PE (1) | PE20091222A1 (https=) |
| TN (1) | TN2010000125A1 (https=) |
| TW (1) | TW200927091A (https=) |
| WO (1) | WO2009048527A1 (https=) |
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| NZ601408A (en) | 2009-12-25 | 2013-12-20 | Mochida Pharm Co Ltd | Novel 3-hydroxy-5-arylisothiazole derivative |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8299117B2 (en) | 2010-06-16 | 2012-10-30 | Metabolex Inc. | GPR120 receptor agonists and uses thereof |
| JP5746334B2 (ja) * | 2010-06-16 | 2015-07-08 | シマベイ セラピューティクス， インコーポレーテッド | Ｇｐｒ１２０受容体作動薬及びその使用 |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
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| JP5809157B2 (ja) | 2010-10-08 | 2015-11-10 | 持田製薬株式会社 | 環状アミド誘導体 |
| CN102617501A (zh) * | 2011-01-31 | 2012-08-01 | 中国科学院上海药物研究所 | 取代正戊酰胺类化合物、其制备方法及用途 |
| BR112013027883A2 (pt) | 2011-04-27 | 2017-08-08 | Mochida Pharm Co Ltd | novo derivado de 1-óxido de 3-hidroxiisotiazol |
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| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
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| US9527875B2 (en) | 2012-08-02 | 2016-12-27 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| WO2014064215A1 (en) | 2012-10-24 | 2014-05-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING β-CELL SURVIVAL |
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| WO2014078610A1 (en) | 2012-11-16 | 2014-05-22 | Bristol-Myers Squibb Company | Dihydropyrazole gpr40 modulators |
| RU2015140066A (ru) | 2013-02-22 | 2017-03-30 | Мерк Шарп И Доум Корп. | Противодиабетические бициклические соединения |
| CN105189439B (zh) * | 2013-03-14 | 2017-12-29 | 百时美施贵宝公司 | 二环[2.2.1]酸gpr120调节剂 |
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| PT3031799T (pt) * | 2013-08-09 | 2018-07-04 | Takeda Pharmaceuticals Co | Composto aromático |
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| IN2013MU03577A (https=) | 2013-11-14 | 2015-07-31 | Cadila Healthcare Ltd | |
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| EP3076959B1 (en) | 2013-12-04 | 2018-07-04 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
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| EP3102198B1 (en) | 2014-02-06 | 2020-08-26 | Merck Sharp & Dohme Corp. | Antidiabetic compounds |
| WO2015176267A1 (en) | 2014-05-22 | 2015-11-26 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| US10662171B2 (en) | 2014-08-08 | 2020-05-26 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| WO2016022446A1 (en) | 2014-08-08 | 2016-02-11 | Merck Sharp & Dohme Corp. | [5,6]-fused bicyclic antidiabetic compounds |
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| US10968193B2 (en) | 2014-08-08 | 2021-04-06 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| US10426818B2 (en) | 2015-03-24 | 2019-10-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Method and pharmaceutical composition for use in the treatment of diabetes |
| WO2017172505A1 (en) | 2016-03-29 | 2017-10-05 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| US11072602B2 (en) | 2016-12-06 | 2021-07-27 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| WO2018118670A1 (en) | 2016-12-20 | 2018-06-28 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
| JPWO2018181847A1 (ja) | 2017-03-31 | 2020-03-05 | 武田薬品工業株式会社 | 芳香環化合物 |
| AR111199A1 (es) | 2017-03-31 | 2019-06-12 | Takeda Pharmaceuticals Co | Compuesto aromático agonista de gpr40 |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| EP3709995A4 (en) | 2017-11-16 | 2021-04-14 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| TWI707849B (zh) | 2018-02-13 | 2020-10-21 | 美商基利科學股份有限公司 | Pd‐1/pd‐l1抑制劑 |
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| EP3820572B1 (en) | 2018-07-13 | 2023-08-16 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| US20220152164A1 (en) * | 2019-03-22 | 2022-05-19 | Kallyope, Inc. | Gpcr combination therapies |
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| US20260109715A1 (en) | 2022-10-03 | 2026-04-23 | Public University Corporation Yokohama City University | Imidazopyridine derivatives with bicyclic structure |
| CN118829638A (zh) * | 2023-02-07 | 2024-10-22 | 宁康瑞珠生物制药(珠海)有限公司 | 偶联化合物和组合物 |
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| CN117603029B (zh) * | 2023-11-21 | 2025-12-19 | 江苏禾本生化有限公司 | 一种戊菌唑关键中间体的合成方法 |
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| EP2139843B1 (en) | 2007-04-16 | 2013-12-25 | Amgen, Inc | Substituted biphenyl phenoxy-, thiophenyl- and aminophenylpropanoic acid gpr40 modulators |
-
2008
- 2008-10-03 CN CN2008801199462A patent/CN102083783A/zh active Pending
- 2008-10-03 JP JP2010528867A patent/JP5591706B2/ja not_active Expired - Fee Related
- 2008-10-03 MX MX2010003876A patent/MX2010003876A/es active IP Right Grant
- 2008-10-03 CA CA2702047A patent/CA2702047C/en not_active Expired - Fee Related
- 2008-10-03 EP EP08837085A patent/EP2205548A1/en not_active Withdrawn
- 2008-10-03 AU AU2008311355A patent/AU2008311355B2/en not_active Ceased
- 2008-10-03 US US12/287,036 patent/US8030354B2/en active Active
- 2008-10-03 KR KR1020107010209A patent/KR20100090249A/ko not_active Withdrawn
- 2008-10-03 WO PCT/US2008/011422 patent/WO2009048527A1/en not_active Ceased
- 2008-10-03 BR BRPI0818253-1A patent/BRPI0818253A2/pt not_active Application Discontinuation
- 2008-10-09 CL CL2008002997A patent/CL2008002997A1/es unknown
- 2008-10-09 PE PE2008001746A patent/PE20091222A1/es not_active Application Discontinuation
- 2008-10-09 AR ARP080104409A patent/AR068840A1/es not_active Application Discontinuation
- 2008-10-09 TW TW097139006A patent/TW200927091A/zh unknown
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2010
- 2010-03-21 IL IL204635A patent/IL204635A0/en unknown
- 2010-03-22 TN TNP2010000125A patent/TN2010000125A1/fr unknown
- 2010-05-06 CO CO10054070A patent/CO6270312A2/es not_active Application Discontinuation
- 2010-05-10 MA MA32826A patent/MA31841B1/fr unknown
- 2010-05-10 CR CR11420A patent/CR11420A/es not_active Application Discontinuation
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