CN102083783A - 取代的联苯gpr40调节剂 - Google Patents

取代的联苯gpr40调节剂 Download PDF

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Publication number
CN102083783A
CN102083783A CN2008801199462A CN200880119946A CN102083783A CN 102083783 A CN102083783 A CN 102083783A CN 2008801199462 A CN2008801199462 A CN 2008801199462A CN 200880119946 A CN200880119946 A CN 200880119946A CN 102083783 A CN102083783 A CN 102083783A
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China
Prior art keywords
alkyl
compound
alkenyl
formula
methyl
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Pending
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CN2008801199462A
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Chinese (zh)
Inventor
S·P·布朗
Q·曹
P·J·德兰斯菲尔德
X·杜
J·霍泽
X·Y·焦
金龙在
T·J·科恩
S·赖
A·-R·李
D·林
J·罗
J·C·梅迪娜
J·D·里根
V·帕塔罗鹏
M·希瓦斯
W·沈
Y·苏
G·斯瓦米纳思
M·维莫尔拉塔纳
X·王
Y·熊
L·杨
M·于
J·张
L·朱
Z·付
J·刘
Y·王
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Amgen Inc
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Amgen Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40338063&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN102083783(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CN102083783A publication Critical patent/CN102083783A/zh
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN2008801199462A 2007-10-10 2008-10-03 取代的联苯gpr40调节剂 Pending CN102083783A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US99878607P 2007-10-10 2007-10-10
US60/998786 2007-10-10
US6872408P 2008-03-06 2008-03-06
US61/068724 2008-03-06
PCT/US2008/011422 WO2009048527A1 (en) 2007-10-10 2008-10-03 Substituted biphenyl gpr40 modulators

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CN102083783A true CN102083783A (zh) 2011-06-01

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CN2008801199462A Pending CN102083783A (zh) 2007-10-10 2008-10-03 取代的联苯gpr40调节剂

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US (1) US8030354B2 (https=)
EP (1) EP2205548A1 (https=)
JP (1) JP5591706B2 (https=)
KR (1) KR20100090249A (https=)
CN (1) CN102083783A (https=)
AR (1) AR068840A1 (https=)
AU (1) AU2008311355B2 (https=)
BR (1) BRPI0818253A2 (https=)
CA (1) CA2702047C (https=)
CL (1) CL2008002997A1 (https=)
CO (1) CO6270312A2 (https=)
CR (1) CR11420A (https=)
IL (1) IL204635A0 (https=)
MA (1) MA31841B1 (https=)
MX (1) MX2010003876A (https=)
PE (1) PE20091222A1 (https=)
TN (1) TN2010000125A1 (https=)
TW (1) TW200927091A (https=)
WO (1) WO2009048527A1 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104059039A (zh) * 2013-03-22 2014-09-24 正大天晴药业集团股份有限公司 具有gpr40受体功能调节作用的稠环化合物
CN105189439A (zh) * 2013-03-14 2015-12-23 百时美施贵宝公司 二环[2.2.1]酸gpr120调节剂
CN110719903A (zh) * 2017-03-31 2020-01-21 武田药品工业株式会社 芳族环化合物
WO2022028317A1 (en) * 2020-08-05 2022-02-10 Rezubio Pharmaceuticals Co., Ltd Antidiabetic compounds and compositions
WO2023134712A1 (en) * 2022-01-14 2023-07-20 Rezubio Pharmaceuticals Co., Ltd Antidiabetic compounds and compositions
CN117603029A (zh) * 2023-11-21 2024-02-27 江苏禾本生化有限公司 一种戊菌唑关键中间体的合成方法
WO2024164915A1 (en) * 2023-02-07 2024-08-15 Rezubio Pharmaceuticals Co., Ltd Conjugate compounds and compositions
WO2024188313A1 (zh) * 2023-03-14 2024-09-19 凯思凯迪（上海）医药科技有限公司 苯并杂环类化合物、其制备方法和其应用

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101868452B (zh) 2007-10-10 2014-08-06 诺华股份有限公司 螺环吡咯烷类与其对抗hcv和hiv感染的应用
WO2009111056A1 (en) * 2008-03-06 2009-09-11 Amgen Inc. Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders
AU2009303475B2 (en) * 2008-10-15 2012-09-13 Amgen Inc. Spirocyclic GPR40 modulators
AR074760A1 (es) 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
NZ601408A (en) 2009-12-25 2013-12-20 Mochida Pharm Co Ltd Novel 3-hydroxy-5-arylisothiazole derivative
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