JP2008530242A5 - - Google Patents

Download PDF

Info

Publication number
JP2008530242A5
JP2008530242A5 JP2007556366A JP2007556366A JP2008530242A5 JP 2008530242 A5 JP2008530242 A5 JP 2008530242A5 JP 2007556366 A JP2007556366 A JP 2007556366A JP 2007556366 A JP2007556366 A JP 2007556366A JP 2008530242 A5 JP2008530242 A5 JP 2008530242A5
Authority
JP
Japan
Prior art keywords
substituted
unsubstituted
group
alkyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007556366A
Other languages
English (en)
Japanese (ja)
Other versions
JP5134974B2 (ja
JP2008530242A (ja
Filing date
Publication date
Priority claimed from US11/096,718 external-priority patent/US7521465B2/en
Application filed filed Critical
Publication of JP2008530242A publication Critical patent/JP2008530242A/ja
Publication of JP2008530242A5 publication Critical patent/JP2008530242A5/ja
Application granted granted Critical
Publication of JP5134974B2 publication Critical patent/JP5134974B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2007556366A 2005-02-17 2006-02-17 血漿中のグルコースレベル、コレステロールレベル及びトリグリセリドレベルを低下させるための5−[4−(4−(2−アミノ−2−メトキシカルボニルエチル)フェノキシ)ベンジリデン]チアゾリジン−2,4−ジオン誘導体及び関連化合物 Expired - Fee Related JP5134974B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN347/DEL/2005 2005-02-17
IN347DE2005 2005-02-17
US11/096,718 US7521465B2 (en) 2003-01-17 2005-03-31 Diphenyl ether derivatives
US11/096,718 2005-03-31
PCT/US2006/005846 WO2006089225A1 (en) 2005-02-17 2006-02-17 5- [4- (4- (2 -amino- 2 -methoxycarbonylethyl) phenoxy) benzilidene] thiazolidin-2 , 4-dion e derivatives and related compounds for reducing glucose, cholesterol and triglyceride levels in plasma

Publications (3)

Publication Number Publication Date
JP2008530242A JP2008530242A (ja) 2008-08-07
JP2008530242A5 true JP2008530242A5 (https=) 2009-04-16
JP5134974B2 JP5134974B2 (ja) 2013-01-30

Family

ID=36570583

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007556366A Expired - Fee Related JP5134974B2 (ja) 2005-02-17 2006-02-17 血漿中のグルコースレベル、コレステロールレベル及びトリグリセリドレベルを低下させるための5−[4−(4−(2−アミノ−2−メトキシカルボニルエチル)フェノキシ)ベンジリデン]チアゾリジン−2,4−ジオン誘導体及び関連化合物

Country Status (9)

Country Link
US (1) US7521465B2 (https=)
EP (1) EP1848700B1 (https=)
JP (1) JP5134974B2 (https=)
KR (1) KR20070105364A (https=)
CA (1) CA2598087C (https=)
ES (1) ES2566337T3 (https=)
HU (1) HUE028882T2 (https=)
PL (1) PL1848700T3 (https=)
WO (1) WO2006089225A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9969980B2 (en) * 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
US9969977B2 (en) * 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
US7521465B2 (en) 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
US7781464B2 (en) * 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
KR100814109B1 (ko) 2006-01-09 2008-03-14 한국생명공학연구원 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물
EP2066800A2 (en) * 2006-08-04 2009-06-10 Decode Genetics EHF Aryl amino acid derivatives as inhibitors of lta4h (leukotriene a4 hydrolase) for treating inflammation
US20090069313A1 (en) * 2007-09-06 2009-03-12 Orchid Research Laboratories Ltd. Novel MAO-A inhibitors
WO2009143041A1 (en) 2008-05-20 2009-11-26 Merck & Co., Inc. Efficient production of heterologous proteins using mannosyl transferase inhibitors
CN103108634B (zh) * 2010-07-28 2015-08-12 幽兰化学医药有限公司 用于治疗肝病、肺病、糖尿病并发症和心血管疾病的二苯醚化合物
US9056862B2 (en) 2011-05-10 2015-06-16 National University Corporation Kobe University Thioxothiazolidine derivative having Ras function inhibitory effect
US11117877B2 (en) 2014-11-21 2021-09-14 Bsim Therapeutics, S.A. 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof
TW202019923A (zh) * 2018-07-16 2020-06-01 義大利商吉斯藥品公司 作為Rho-激酶抑制劑之酪胺酸醯胺衍生物

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0228168A (ja) * 1988-04-14 1990-01-30 Sankyo Co Ltd チアゾール誘導体
US20020049240A1 (en) 1994-12-19 2002-04-25 Beecham Group P.1.C. Novel compounds
US5166137A (en) 1991-03-27 1992-11-24 Nobipols Forskningsstiftelse Guluronic acid polymers and use of same for inhibition of cytokine production
US5441971A (en) 1991-04-11 1995-08-15 The Upjohn Company Thiazolidinedione derivatives, production and use thereof
TW268952B (https=) 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
US5527546A (en) 1994-08-10 1996-06-18 Bayer Corporation Human interleukin 6 inhibitor
ATE271128T1 (de) 1995-05-11 2004-07-15 Applied Research Systems Inhibitoren der il-6 aktivitaet
TW577875B (en) 1997-01-31 2004-03-01 Shionogi & Co Pyrrolidine derivatives with inhibitory activity for phospholipase A2
US6331633B1 (en) 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
WO1999064417A2 (en) 1998-06-05 1999-12-16 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
WO2000000194A1 (en) 1998-06-27 2000-01-06 Photogenesis, Inc. Ophthalmic uses of ppargamma agonists and ppargamma antagonists
US6664281B1 (en) 1998-08-27 2003-12-16 Ono Pharmaceutical Co., Ltd. Carboxylic acid derivatives and drugs containing the same as the active ingredient
AU757729B2 (en) 1999-04-07 2003-03-06 Sankyo Company Limited Amine derivatives
YU72201A (sh) 1999-04-28 2005-07-19 Aventis Pharma Deutschland Gmbh. Derivati di-aril kiseline kao ppar receptorski ligandi
TWI284533B (en) 1999-05-24 2007-08-01 Sankyo Co Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant
KR20010099634A (ko) 1999-07-01 2001-11-09 할리 켈빈 비. 텔로머라제 저해제 및 그 사용 방법
CN1155586C (zh) 1999-08-23 2004-06-30 杏林制药株式会社 取代的苄基噻唑烷-2,4-二酮衍生物
JP2003508391A (ja) 1999-08-31 2003-03-04 マキシア・ファーマシューティカルズ・インコーポレイテッド ベンジリデン−チアゾリジンジオン類およびアナログ類ならびに糖尿病の治療におけるその使用
JP2001199888A (ja) 2000-01-24 2001-07-24 Fujimoto Brothers:Kk 糖尿病治療剤
JP2001308814A (ja) 2000-04-19 2001-11-02 Hitachi Ltd フレーム構成自動識別通信装置
EP1148054B1 (en) 2000-04-21 2005-11-23 Pfizer Products Inc. Thyroid receptor ligands
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6525202B2 (en) * 2000-07-17 2003-02-25 Wyeth Cyclic amine phenyl beta-3 adrenergic receptor agonists
CA2460541A1 (en) 2001-09-14 2003-04-03 Helle Birk Olsen Novel ligands for the hisb10 zn2+ sites of the r-state insulin hexamer
JP2005513026A (ja) * 2001-11-15 2005-05-12 インサイト サン ディエゴ インコーポレイテッド 高コレステロール血症、異脂肪血症および他の代謝障害;癌、および他の疾患を治療するn−置換複素環
US7521465B2 (en) 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
US6794401B2 (en) 2003-01-17 2004-09-21 Bexel Pharmaceuticals, Inc. Amino acid phenoxy ethers
JP2007523842A (ja) 2003-03-11 2007-08-23 ノボ ノルディスク アクティーゼルスカブ 酸安定化されたインスリンを含有する薬学的製剤
US7087576B2 (en) 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers

Similar Documents

Publication Publication Date Title
KR102084109B1 (ko) 캡 의존적 엔도뉴클레아제 저해제 및 항인플루엔자 약을 조합하는 것을 특징으로 하는 인플루엔자 치료용 의약
JP6553059B2 (ja) Hbv感染の治療のための併用療法
JP2019069941A (ja) スルファモイル−アリールアミド及びb型肝炎の治療のための薬剤としてのその使用
RU2006105717A (ru) Производные пиперазина и их применение в качестве терапевтических агентов
JP2008530242A5 (https=)
WO1993022298A1 (fr) Derive d'oxazolidine et son sel pharmaceutiquement acceptable
TW200522941A (en) Method for modulating calcium ion-release-activated calcium ion channels
JP2008513515A5 (https=)
JP2008513498A5 (https=)
JP2009528997A5 (https=)
JP5539978B2 (ja) チアゾピリミジノンおよびその使用
IL287159B2 (en) Small molecules agonists for FXR (farnesoid X receptor) and method for their preparation and use
JP2024515062A (ja) 重水素化dhodh阻害剤
JP2011516511A5 (https=)
CA2500977A1 (en) 2-thiohydantoine derivative compounds and use thereof in therapeutics
RU2007108863A (ru) Производные пиразола для лечения состояний, опосредованных активацией рецептора аденозина а2в или а3
RU2007108415A (ru) Новое циклическое производное аминобензойной кислоты
JP2004529145A5 (https=)
KR100718906B1 (ko) 디히드로나프탈렌 유도체 화합물 및 이 화합물을 유효성분으로 하는 약제
JP2004525183A5 (https=)
JP5890064B2 (ja) 4−((置換フェニル)ジフルオロメチル)フェノキシカルボン酸誘導体およびその調製方法およびその使用
CN1159305C (zh) 新的2-(n-氰基亚氨基)噻唑烷-4-酮衍生物
JP2020520949A5 (https=)
ES2642172T3 (es) Compuestos derivados de ciclohexeno sustituidos con biarilo o biarilo heterocíclico como inhibidores de CETP
WO2015102369A1 (ko) 1,2 나프토퀴논 유도체 및 이의 제조방법