CA2598087C - 5-[4-(4-(2-amino-2 methoxycarbonylethyl)phenoxy)benzilidene]thiazolidin-2,4-dione derivatives and related compounds for reducing glucose, cholesterol and triglyceride levels in plasma - Google Patents
5-[4-(4-(2-amino-2 methoxycarbonylethyl)phenoxy)benzilidene]thiazolidin-2,4-dione derivatives and related compounds for reducing glucose, cholesterol and triglyceride levels in plasma Download PDFInfo
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- CA2598087C CA2598087C CA2598087A CA2598087A CA2598087C CA 2598087 C CA2598087 C CA 2598087C CA 2598087 A CA2598087 A CA 2598087A CA 2598087 A CA2598087 A CA 2598087A CA 2598087 C CA2598087 C CA 2598087C
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- amino
- thiazolidin
- phenyl
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Classifications
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN347/DEL/2005 | 2005-02-17 | ||
| IN347DE2005 | 2005-02-17 | ||
| US11/096,718 US7521465B2 (en) | 2003-01-17 | 2005-03-31 | Diphenyl ether derivatives |
| US11/096,718 | 2005-03-31 | ||
| PCT/US2006/005846 WO2006089225A1 (en) | 2005-02-17 | 2006-02-17 | 5- [4- (4- (2 -amino- 2 -methoxycarbonylethyl) phenoxy) benzilidene] thiazolidin-2 , 4-dion e derivatives and related compounds for reducing glucose, cholesterol and triglyceride levels in plasma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2598087A1 CA2598087A1 (en) | 2006-08-24 |
| CA2598087C true CA2598087C (en) | 2014-05-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2598087A Expired - Fee Related CA2598087C (en) | 2005-02-17 | 2006-02-17 | 5-[4-(4-(2-amino-2 methoxycarbonylethyl)phenoxy)benzilidene]thiazolidin-2,4-dione derivatives and related compounds for reducing glucose, cholesterol and triglyceride levels in plasma |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7521465B2 (https=) |
| EP (1) | EP1848700B1 (https=) |
| JP (1) | JP5134974B2 (https=) |
| KR (1) | KR20070105364A (https=) |
| CA (1) | CA2598087C (https=) |
| ES (1) | ES2566337T3 (https=) |
| HU (1) | HUE028882T2 (https=) |
| PL (1) | PL1848700T3 (https=) |
| WO (1) | WO2006089225A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US9969980B2 (en) * | 2001-09-21 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| US9969977B2 (en) * | 2002-09-20 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| US7521465B2 (en) | 2003-01-17 | 2009-04-21 | Bexel Pharmaceuticals, Inc. | Diphenyl ether derivatives |
| US7781464B2 (en) * | 2003-01-17 | 2010-08-24 | Bexel Pharmaceuticals, Inc. | Heterocyclic diphenyl ethers |
| US7087576B2 (en) * | 2003-10-07 | 2006-08-08 | Bexel Pharmaceuticals, Inc. | Dipeptide phenyl ethers |
| KR100814109B1 (ko) | 2006-01-09 | 2008-03-14 | 한국생명공학연구원 | 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물 |
| EP2066800A2 (en) * | 2006-08-04 | 2009-06-10 | Decode Genetics EHF | Aryl amino acid derivatives as inhibitors of lta4h (leukotriene a4 hydrolase) for treating inflammation |
| US20090069313A1 (en) * | 2007-09-06 | 2009-03-12 | Orchid Research Laboratories Ltd. | Novel MAO-A inhibitors |
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-
2005
- 2005-03-31 US US11/096,718 patent/US7521465B2/en not_active Expired - Fee Related
-
2006
- 2006-02-17 CA CA2598087A patent/CA2598087C/en not_active Expired - Fee Related
- 2006-02-17 KR KR1020077021343A patent/KR20070105364A/ko not_active Ceased
- 2006-02-17 PL PL06735487T patent/PL1848700T3/pl unknown
- 2006-02-17 ES ES06735487.8T patent/ES2566337T3/es not_active Expired - Lifetime
- 2006-02-17 JP JP2007556366A patent/JP5134974B2/ja not_active Expired - Fee Related
- 2006-02-17 WO PCT/US2006/005846 patent/WO2006089225A1/en not_active Ceased
- 2006-02-17 HU HUE06735487A patent/HUE028882T2/en unknown
- 2006-02-17 EP EP06735487.8A patent/EP1848700B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP5134974B2 (ja) | 2013-01-30 |
| KR20070105364A (ko) | 2007-10-30 |
| ES2566337T3 (es) | 2016-04-12 |
| HUE028882T2 (en) | 2017-01-30 |
| JP2008530242A (ja) | 2008-08-07 |
| US20050288341A1 (en) | 2005-12-29 |
| US7521465B2 (en) | 2009-04-21 |
| WO2006089225A1 (en) | 2006-08-24 |
| EP1848700A1 (en) | 2007-10-31 |
| EP1848700B1 (en) | 2015-12-30 |
| CA2598087A1 (en) | 2006-08-24 |
| PL1848700T3 (pl) | 2016-08-31 |
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