JP2010523079A5 - - Google Patents
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- JP2010523079A5 JP2010523079A5 JP2010500298A JP2010500298A JP2010523079A5 JP 2010523079 A5 JP2010523079 A5 JP 2010523079A5 JP 2010500298 A JP2010500298 A JP 2010500298A JP 2010500298 A JP2010500298 A JP 2010500298A JP 2010523079 A5 JP2010523079 A5 JP 2010523079A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- motif
- polynucleotide
- mature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920001184 polypeptide Polymers 0.000 claims 46
- 102000004196 processed proteins & peptides Human genes 0.000 claims 46
- 108090000765 processed proteins & peptides Proteins 0.000 claims 46
- 238000000034 method Methods 0.000 claims 10
- 108091033319 polynucleotide Proteins 0.000 claims 8
- 102000040430 polynucleotide Human genes 0.000 claims 8
- 239000002157 polynucleotide Substances 0.000 claims 8
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 7
- 108010023506 peroxygenase Proteins 0.000 claims 7
- 239000002773 nucleotide Substances 0.000 claims 6
- 125000003729 nucleotide group Chemical group 0.000 claims 6
- 108091026890 Coding region Proteins 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 239000007800 oxidant agent Substances 0.000 claims 3
- 241000588724 Escherichia coli Species 0.000 claims 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical group OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 239000003599 detergent Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 241000222501 Agaricaceae Species 0.000 claims 1
- 244000045069 Agrocybe aegerita Species 0.000 claims 1
- 235000008121 Agrocybe aegerita Nutrition 0.000 claims 1
- 241001660920 Agrocybe chaxingu Species 0.000 claims 1
- 241000222531 Bolbitiaceae Species 0.000 claims 1
- 241001236774 Coprinellus radians Species 0.000 claims 1
- 241000222511 Coprinus Species 0.000 claims 1
- 150000001204 N-oxides Chemical class 0.000 claims 1
- 241000222433 Tricholomataceae Species 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 230000003197 catalytic effect Effects 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 238000005580 one pot reaction Methods 0.000 claims 1
- 150000001451 organic peroxides Chemical class 0.000 claims 1
- 230000003647 oxidation Effects 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 230000001590 oxidative effect Effects 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 125000004585 polycyclic heterocycle group Chemical group 0.000 claims 1
- 150000003222 pyridines Chemical class 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
- 238000003259 recombinant expression Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007016139A DE102007016139A1 (de) | 2007-03-30 | 2007-03-30 | Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen |
| DE102007016139.7 | 2007-03-30 | ||
| PCT/EP2008/053798 WO2008119780A2 (en) | 2007-03-30 | 2008-03-31 | Fungal peroxygenases and methods of application |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013171739A Division JP2014000086A (ja) | 2007-03-30 | 2013-08-21 | 真菌ペルオキシゲナーゼ及び適用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010523079A JP2010523079A (ja) | 2010-07-15 |
| JP2010523079A5 true JP2010523079A5 (https=) | 2011-05-19 |
| JP5411121B2 JP5411121B2 (ja) | 2014-02-12 |
Family
ID=39591196
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500298A Expired - Fee Related JP5411121B2 (ja) | 2007-03-30 | 2008-03-31 | 真菌ペルオキシゲナーゼ及び適用方法 |
| JP2013171739A Pending JP2014000086A (ja) | 2007-03-30 | 2013-08-21 | 真菌ペルオキシゲナーゼ及び適用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013171739A Pending JP2014000086A (ja) | 2007-03-30 | 2013-08-21 | 真菌ペルオキシゲナーゼ及び適用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8367387B2 (https=) |
| EP (3) | EP2158313B1 (https=) |
| JP (2) | JP5411121B2 (https=) |
| CN (1) | CN101802180B (https=) |
| AT (1) | ATE548449T1 (https=) |
| CA (1) | CA2682451C (https=) |
| DE (1) | DE102007016139A1 (https=) |
| DK (1) | DK2158313T3 (https=) |
| WO (1) | WO2008119780A2 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9222109B2 (en) | 2010-03-28 | 2015-12-29 | Novozymes A/S | Enzymatic hydroxylation of aliphatic hydrocarbon |
| WO2013004639A2 (en) | 2011-07-07 | 2013-01-10 | Novozymes A/S | Enzymatic preparation of diols |
| WO2013021060A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021065A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021062A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021059A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021064A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| CN103732740B (zh) | 2011-08-10 | 2018-07-31 | 诺维信公司 | 具有过氧化酶活性的多肽及编码该多肽的多核苷酸 |
| WO2013021061A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013079531A2 (en) | 2011-12-02 | 2013-06-06 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013079533A1 (en) | 2011-12-02 | 2013-06-06 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013144105A1 (en) | 2012-03-31 | 2013-10-03 | Novozymes A/S | Epoxidation using peroxygenase |
| EP2875179B1 (en) | 2012-07-18 | 2018-02-21 | Novozymes A/S | Method of treating polyester textile |
| CN104781412A (zh) | 2012-07-20 | 2015-07-15 | 诺维信公司 | 5-羟甲基糠醛及其衍生物的酶氧化 |
| EP2906688B1 (en) | 2012-10-12 | 2018-08-29 | Novozymes A/S | Polypeptides having peroxygenase activity |
| CN104704116B (zh) * | 2012-10-12 | 2018-09-28 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| WO2014056927A2 (en) | 2012-10-12 | 2014-04-17 | Novozymes A/S | Polypeptides having peroxygenase activity |
| US9453207B2 (en) | 2012-10-12 | 2016-09-27 | Novozymes A/S | Polypeptides having peroxygenase activity |
| US9458435B2 (en) | 2012-10-12 | 2016-10-04 | Novozymes A/S | Polypeptides having peroxygenase activity |
| CN104718288B (zh) * | 2012-10-12 | 2018-11-16 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| CN104704114A (zh) * | 2012-10-12 | 2015-06-10 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| US9534208B2 (en) | 2012-10-12 | 2017-01-03 | Novozymes A/S | Polypeptides having peroxygenase activity |
| WO2014090940A1 (en) * | 2012-12-14 | 2014-06-19 | Novozymes A/S | Removal of skin-derived body soils |
| EP2871233A1 (de) | 2013-11-12 | 2015-05-13 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur Herstellung von biogenen Stoffen |
| JP6291051B2 (ja) * | 2013-11-18 | 2018-03-14 | エンザイマティック デインキング テクノロジーズ， エルエルシー | 製紙用バージン繊維及び再生紙の残存鉱油濃度低減のための酵素処理 |
| WO2015079064A2 (en) | 2013-11-29 | 2015-06-04 | Novozymes A/S | Peroxygenase variants |
| WO2016207373A1 (en) | 2015-06-26 | 2016-12-29 | Novozymes A/S | Polypeptides having peroxygenase activity |
| DK3392341T3 (da) | 2017-04-20 | 2021-04-06 | Consejo Superior Investigacion | Fremgangsmåde til afkortning af carbonhydridkæden i en carboxylsyre ved hjælp af en peroxygenase |
| NL2021113B1 (en) * | 2018-06-13 | 2019-12-19 | Univ Delft Tech | Synthesis of aromatic epoxide derived compounds |
| US11866757B2 (en) | 2018-07-03 | 2024-01-09 | Ruhr-Universitaet Bochum | Plasma-driven biocatalysis |
| EP3594332A1 (en) * | 2018-07-10 | 2020-01-15 | Consejo Superior de Investigaciones Cientificas | Method of heterologous expression of active fungal unspecific peroxygenase in bacterial host cells for fatty-acid epoxidation and other oxygenation reactions |
| EP3660147A1 (en) | 2018-11-30 | 2020-06-03 | Consejo Superior de Investigaciones Cientificas (CSIC) | Process for selective synthesis of 4-hydroxyisophorone and 4-ketoisophorone by fungal peroxygenases |
| WO2020142599A1 (en) * | 2019-01-03 | 2020-07-09 | Locus Oil Ip Company, Llc | Materials and methods for extended reduction of heavy crude oil viscosity |
| EP3994252A1 (en) | 2019-07-05 | 2022-05-11 | bisy GmbH | Recombinant heme thiolate oxygenases |
| US20240010996A1 (en) | 2020-09-23 | 2024-01-11 | Gecco Biotech B.V. | Bacterial unspecific peroxygenases (BUPO's) and methods and uses thereof |
| DE102021204094A1 (de) | 2021-04-25 | 2022-10-27 | Brandenburgische Technische Universität Cottbus-Senftenberg | In-vitro Arzneimittel aus Prodrugs und deren Verwendung |
| EP4396194A1 (de) | 2021-09-03 | 2024-07-10 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur zellfreien herstellung von unspezifischen peroxygenasen |
| DE102021209758A1 (de) | 2021-09-03 | 2023-03-09 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur zellfreien Herstellung von unspezifischen Peroxygenasen und deren Verwendung |
| DE102021214582A1 (de) | 2021-12-17 | 2023-06-22 | Brandenburgische Technische Universität Cottbus-Senftenberg | Verfahren zur zellfreien Herstellung von unspezifischen Peroxygenasen und deren Verwendung |
| CN116240246B (zh) * | 2021-12-20 | 2025-01-21 | 浙江金朗博药业有限公司 | 利用过氧化物酶合成骨化二醇的方法 |
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| CN1197965C (zh) | 1998-10-26 | 2005-04-20 | 诺维信公司 | 在丝状真菌细胞内构建和筛选目的dna文库 |
| CN100510096C (zh) | 1999-03-22 | 2009-07-08 | 诺沃奇梅兹有限公司 | 用于在真菌细胞中表达基因的启动子 |
| DE10332065A1 (de) | 2003-07-11 | 2005-01-27 | Friedrich-Schiller-Universität Jena | Verfahren zur enzymatischen Darstellung von Säuren aus Alkoholen über die intermediäre Bildung von Aldehyden |
| DE602004022967D1 (de) | 2003-10-30 | 2009-10-15 | Novozymes As | Kohlenhydratbindende module |
| DE102004047774A1 (de) | 2004-09-28 | 2006-03-30 | Jenabios Gmbh | Verfahren zur enzymatischen Hydroxylierung nicht-aktivierter Kohlenwasserstoffe |
| US8026085B2 (en) * | 2006-08-04 | 2011-09-27 | California Institute Of Technology | Methods and systems for selective fluorination of organic molecules |
-
2007
- 2007-03-30 DE DE102007016139A patent/DE102007016139A1/de not_active Withdrawn
-
2008
- 2008-03-31 EP EP08718350A patent/EP2158313B1/en not_active Not-in-force
- 2008-03-31 US US12/532,870 patent/US8367387B2/en not_active Expired - Fee Related
- 2008-03-31 CN CN200880017970.5A patent/CN101802180B/zh not_active Expired - Fee Related
- 2008-03-31 WO PCT/EP2008/053798 patent/WO2008119780A2/en not_active Ceased
- 2008-03-31 DK DK08718350.5T patent/DK2158313T3/da active
- 2008-03-31 JP JP2010500298A patent/JP5411121B2/ja not_active Expired - Fee Related
- 2008-03-31 AT AT08718350T patent/ATE548449T1/de active
- 2008-03-31 CA CA2682451A patent/CA2682451C/en not_active Expired - Fee Related
- 2008-03-31 EP EP12161074A patent/EP2471911A3/en not_active Withdrawn
- 2008-03-31 EP EP12158017.9A patent/EP2468852B1/en not_active Not-in-force
-
2012
- 2012-12-20 US US13/722,019 patent/US20130115662A1/en not_active Abandoned
-
2013
- 2013-08-21 JP JP2013171739A patent/JP2014000086A/ja active Pending
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