JP2006524053A5 - - Google Patents
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- Publication number
- JP2006524053A5 JP2006524053A5 JP2006509391A JP2006509391A JP2006524053A5 JP 2006524053 A5 JP2006524053 A5 JP 2006524053A5 JP 2006509391 A JP2006509391 A JP 2006509391A JP 2006509391 A JP2006509391 A JP 2006509391A JP 2006524053 A5 JP2006524053 A5 JP 2006524053A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- seq
- polynucleotide sequence
- polynucleotide
- subsequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000039446 nucleic acids Human genes 0.000 claims 40
- 108020004707 nucleic acids Proteins 0.000 claims 40
- 150000007523 nucleic acids Chemical class 0.000 claims 40
- 102000040430 polynucleotide Human genes 0.000 claims 32
- 108091033319 polynucleotide Proteins 0.000 claims 32
- 239000002157 polynucleotide Substances 0.000 claims 32
- 239000002773 nucleotide Substances 0.000 claims 14
- 125000003729 nucleotide group Chemical group 0.000 claims 14
- 108700026244 Open Reading Frames Proteins 0.000 claims 11
- 125000000539 amino acid group Chemical group 0.000 claims 10
- 230000000295 complement effect Effects 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 9
- 102000004196 processed proteins & peptides Human genes 0.000 claims 9
- 108090000765 processed proteins & peptides Proteins 0.000 claims 9
- 241000725643 Respiratory syncytial virus Species 0.000 claims 7
- 241000700605 Viruses Species 0.000 claims 5
- 230000037430 deletion Effects 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 241000711920 Human orthopneumovirus Species 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 238000002741 site-directed mutagenesis Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45833103P | 2003-03-28 | 2003-03-28 | |
| US60/458,331 | 2003-03-28 | ||
| US50832003P | 2003-10-03 | 2003-10-03 | |
| US60/508,320 | 2003-10-03 | ||
| PCT/US2004/009438 WO2004087062A2 (en) | 2003-03-28 | 2004-03-26 | Compositions and methods involving respiratory syncytial virus subgroup b strain 9320 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006524053A JP2006524053A (ja) | 2006-10-26 |
| JP2006524053A5 true JP2006524053A5 (https=) | 2007-05-24 |
| JP4783726B2 JP4783726B2 (ja) | 2011-09-28 |
Family
ID=33135096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509391A Expired - Fee Related JP4783726B2 (ja) | 2003-03-28 | 2004-03-26 | 呼吸器合胞体ウイルスサブグループｂ株９３２０に関連する組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7572904B2 (https=) |
| EP (1) | EP1613345B1 (https=) |
| JP (1) | JP4783726B2 (https=) |
| AT (1) | ATE469170T1 (https=) |
| AU (1) | AU2004226369A1 (https=) |
| CA (1) | CA2520671C (https=) |
| DE (1) | DE602004027362D1 (https=) |
| WO (1) | WO2004087062A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007531491A (ja) * | 2002-09-27 | 2007-11-08 | メディミューン・ヴァクシンズ・インコーポレーテッド | 呼吸器合胞体ウイルスにおける機能的突然変異 |
| EP1613345B1 (en) * | 2003-03-28 | 2010-05-26 | MedImmune, LLC | Compositions and methods involving respiratory syncytial virus subgroup b strain 9320 |
| FR2885139B1 (fr) | 2005-04-29 | 2010-12-24 | Agronomique Inst Nat Rech | Preparation de complexes solubles proteine n-proteine p tronquee ou de proteine n soluble d'un virus de la famille des paramyxoviridae et leurs utilisations vaccinales |
| DK1991694T3 (da) * | 2006-02-13 | 2016-08-01 | Fluidigm Canada Inc | Genekspressionsanalyse med grundstoftagget oligonukleotid |
| WO2007101441A1 (en) * | 2006-03-06 | 2007-09-13 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| FR2899902B1 (fr) * | 2006-04-18 | 2012-01-27 | Agronomique Inst Nat Rech | Proteines de fusion proteine n d'un virus de la famille des paramyxoviridae-proteine d'interet et leurs utilisations pour la vaccination et la vectorisation intra-cellulaire. |
| JP2010534057A (ja) * | 2007-03-06 | 2010-11-04 | シムフォゲン・アクティーゼルスカブ | 呼吸器合胞体ウイルス感染症を治療するための組換え抗体 |
| US20090017517A1 (en) * | 2007-07-13 | 2009-01-15 | Medimmune, Llc | Preparation of Negative-Stranded RNA Viruses by Electroporation |
| US8354230B2 (en) | 2007-12-21 | 2013-01-15 | Quest Diagnostics Investments Inc. | Multiplex detection assay for influenza and RSV viruses |
| US9011876B2 (en) * | 2008-11-05 | 2015-04-21 | Merck Sharp & Dohme Corp. | Live, attenuated respiratory syncytial virus |
| GB201019240D0 (en) | 2010-11-15 | 2010-12-29 | Vib Vzw | Respiratory syncytical virus vaccine |
| US10227569B2 (en) | 2011-04-12 | 2019-03-12 | Emory University | Respiratory syncytial virus expression vectors |
| EP3798310A1 (en) | 2013-03-14 | 2021-03-31 | Emory University | Recombinant rsv with silent mutations, vaccines, and methods related thereto |
| MX2018005462A (es) | 2015-10-29 | 2018-08-01 | Univ Emory | Composiciones inmunogénicas de rsv quimérico y métodos de uso. |
| EP3370767A1 (en) | 2015-11-04 | 2018-09-12 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Method of vaccination with an attenuated rsv vaccine formulation |
| AU2023349013A1 (en) * | 2022-09-29 | 2025-04-17 | Beijing Benewill Technology Development Co., Ltd. | Respiratory syncytial virus recombinant fusion protein with prefusion conformation, and preparation method therefor and use thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4800078A (en) | 1987-05-28 | 1989-01-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Immunotherapeutic method of treating respiratory disease by intranasal administration of Igb |
| US5840520A (en) * | 1989-08-28 | 1998-11-24 | Aviron | Recombinant negative strand RNA virus expression systems |
| GB9200117D0 (en) | 1992-01-06 | 1992-02-26 | Connaught Lab | Production of recombinant chimeric proteins for vaccine use |
| IL105456A (en) | 1992-04-21 | 1996-12-05 | American Home Prod | Vaccines of attenuated respiratory syncytial virus |
| US20030054505A1 (en) * | 1997-09-26 | 2003-03-20 | Hong Jin | Recombinant rsv expression systems and vaccines |
| US6713066B1 (en) | 1996-07-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Production of attenuated respiratory syncytial virus vaccines involving modification of M2 ORF2 |
| CA2265554A1 (en) * | 1996-09-27 | 1998-04-02 | American Cyanamid Company | 3' genomic promoter region and polymerase gene mutations responsible for attenuation in viruses of the order designated mononegavirales |
| US6017694A (en) | 1997-12-19 | 2000-01-25 | American Cyanamid Company | Methods of screening for modulators of respiratory syncytial virus matrix protein interaction |
| CA2323927A1 (en) * | 1998-03-26 | 1999-09-30 | American Cyanamid Company | Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup b |
| JP4268407B2 (ja) | 2000-11-28 | 2009-05-27 | アヴィロン，インコーポレーテッド | 組換えｒｓｖウイルス発現系およびワクチン |
| KR20040002853A (ko) * | 2001-01-19 | 2004-01-07 | 비로노바티브 비.브이. | 감응성 포유류에서 호흡계 질환을 유발하는 바이러스 |
| JP2007531491A (ja) | 2002-09-27 | 2007-11-08 | メディミューン・ヴァクシンズ・インコーポレーテッド | 呼吸器合胞体ウイルスにおける機能的突然変異 |
| EP1613345B1 (en) * | 2003-03-28 | 2010-05-26 | MedImmune, LLC | Compositions and methods involving respiratory syncytial virus subgroup b strain 9320 |
-
2004
- 2004-03-26 EP EP04749465A patent/EP1613345B1/en not_active Expired - Lifetime
- 2004-03-26 WO PCT/US2004/009438 patent/WO2004087062A2/en not_active Ceased
- 2004-03-26 AT AT04749465T patent/ATE469170T1/de not_active IP Right Cessation
- 2004-03-26 AU AU2004226369A patent/AU2004226369A1/en not_active Abandoned
- 2004-03-26 US US10/811,508 patent/US7572904B2/en not_active Expired - Lifetime
- 2004-03-26 CA CA2520671A patent/CA2520671C/en not_active Expired - Fee Related
- 2004-03-26 JP JP2006509391A patent/JP4783726B2/ja not_active Expired - Fee Related
- 2004-03-26 DE DE602004027362T patent/DE602004027362D1/de not_active Expired - Lifetime
-
2009
- 2009-07-23 US US12/508,075 patent/US8163530B2/en not_active Expired - Lifetime
-
2012
- 2012-04-17 US US13/449,087 patent/US20120263744A1/en not_active Abandoned
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