JP2010522212A5 - - Google Patents
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- JP2010522212A5 JP2010522212A5 JP2009554770A JP2009554770A JP2010522212A5 JP 2010522212 A5 JP2010522212 A5 JP 2010522212A5 JP 2009554770 A JP2009554770 A JP 2009554770A JP 2009554770 A JP2009554770 A JP 2009554770A JP 2010522212 A5 JP2010522212 A5 JP 2010522212A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- mesenchymal stem
- stem cells
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 20
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 11
- 241001465754 Metazoa Species 0.000 claims 9
- 208000019693 Lung disease Diseases 0.000 claims 7
- 210000004027 cell Anatomy 0.000 claims 4
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims 3
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 3
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 claims 3
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 claims 3
- 201000000028 adult respiratory distress syndrome Diseases 0.000 claims 3
- 208000006673 asthma Diseases 0.000 claims 3
- 208000036971 interstitial lung disease 2 Diseases 0.000 claims 3
- 208000002815 pulmonary hypertension Diseases 0.000 claims 3
- 230000037396 body weight Effects 0.000 claims 2
- 231100000241 scar Toxicity 0.000 claims 2
- 102000002274 Matrix Metalloproteinases Human genes 0.000 claims 1
- 108010000684 Matrix Metalloproteinases Proteins 0.000 claims 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 1
- 210000002950 fibroblast Anatomy 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 230000004199 lung function Effects 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 230000007115 recruitment Effects 0.000 claims 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/726,676 US20080095749A1 (en) | 2004-03-22 | 2007-03-22 | Mesenchymal stem cells and uses therefor |
| PCT/US2008/057828 WO2008116157A2 (en) | 2007-03-22 | 2008-03-21 | Mesenchymal stem cells and uses therefor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014124452A Division JP5961220B2 (ja) | 2007-03-22 | 2014-06-17 | 間充織幹細胞とその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522212A JP2010522212A (ja) | 2010-07-01 |
| JP2010522212A5 true JP2010522212A5 (cg-RX-API-DMAC7.html) | 2011-03-17 |
Family
ID=39735516
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009554770A Pending JP2010522212A (ja) | 2007-03-22 | 2008-03-21 | 間充織幹細胞とその使用 |
| JP2014124452A Active JP5961220B2 (ja) | 2007-03-22 | 2014-06-17 | 間充織幹細胞とその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014124452A Active JP5961220B2 (ja) | 2007-03-22 | 2014-06-17 | 間充織幹細胞とその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20080095749A1 (cg-RX-API-DMAC7.html) |
| EP (6) | EP4438721A3 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2010522212A (cg-RX-API-DMAC7.html) |
| KR (7) | KR20220166876A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101626772A (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0802241A2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA3134185A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2123747T3 (cg-RX-API-DMAC7.html) |
| ES (3) | ES2988291T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008116157A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005227295A1 (en) | 2004-03-22 | 2005-10-06 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
| EP1729788B1 (en) * | 2004-03-30 | 2009-11-25 | Boston Scientific Limited | Restenosis therapy using mesenchymal stem cells |
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| ES2589311T5 (es) | 2005-09-23 | 2020-02-14 | Tigenix S A U | Poblaciones de células que tienen actividad inmunorreguladora, método de aislamiento y usos |
| KR101378874B1 (ko) | 2005-10-13 | 2014-03-27 | 안트로제네시스 코포레이션 | 태반 줄기세포를 이용한 면역 조절 |
| PT2471907T (pt) | 2005-12-29 | 2019-01-28 | Celularity Inc | Populações de células estaminais placentárias |
| US20090169522A1 (en) | 2006-01-13 | 2009-07-02 | Alla Danilkovitch | Mesenchymal stem cells expressing tnf-a receptor |
| ME01562B (me) | 2007-02-12 | 2014-09-20 | Anthrogenesis Corp | Liječenje protuupalnih bolesti putem matičnih stanica posteljice |
| JP5541845B2 (ja) * | 2008-03-28 | 2014-07-09 | Ｊｃｒファーマ株式会社 | アトピー性皮膚炎治療剤 |
| EP2279246A4 (en) * | 2008-05-02 | 2012-03-28 | Massachusetts Inst Technology | METHOD AND COMPOSITIONS FOR MODULATING IMMUNOLOGICAL TOLERANCE |
| GB0814249D0 (en) * | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
| KR20240052847A (ko) | 2008-08-20 | 2024-04-23 | 셀룰래리티 인코포레이티드 | 개선된 세포 조성물 및 그의 제조 방법 |
| HRP20130812T1 (en) | 2008-08-22 | 2013-09-30 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
| BRPI0919804A8 (pt) * | 2008-10-05 | 2016-10-11 | Friedlander Hymie | Métodos e composição para o tratamento de problemas dermatológicos e/ou condições de cabelo |
| JP5869342B2 (ja) | 2008-11-19 | 2016-02-24 | アンスロジェネシス コーポレーション | 羊膜由来接着細胞 |
| JP6243119B2 (ja) * | 2009-07-21 | 2017-12-06 | エイビーティー ホールディング カンパニー | 白血球溢出を低下させる幹細胞の使用 |
| WO2011070974A1 (ja) * | 2009-12-07 | 2011-06-16 | 国立大学法人名古屋大学 | 脂肪組織由来間葉系幹細胞を含有する、前立腺癌治療用細胞製剤 |
| EP2512516B1 (en) * | 2009-12-18 | 2016-02-17 | The Governing Council Of The University Of Toronto | Injectable polymer composition for use as a cell delivery vehicle |
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| DK2568991T6 (en) | 2010-05-12 | 2019-03-18 | Abt Holding Co | MODULATION OF SPLENOCYTES IN CELL THERAPY |
| EP4663241A2 (en) | 2010-10-08 | 2025-12-17 | Mesoblast International Sàrl | Enhanced msc preparations |
| CN101991880A (zh) * | 2010-11-08 | 2011-03-30 | 中国人民解放军军事医学科学院基础医学研究所 | 由复合msc的plga/tcp和msc组成的制剂及其应用 |
| CN101991878A (zh) * | 2010-11-08 | 2011-03-30 | 中国人民解放军军事医学科学院基础医学研究所 | 由复合msc的plga和msc组成的制剂及其应用 |
| EP2658557A1 (en) | 2010-12-31 | 2013-11-06 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory rna molecules |
| KR102063069B1 (ko) * | 2011-03-11 | 2020-01-08 | 칠드런'즈 메디컬 센터 코포레이션 | 중간엽 줄기 세포 엑소솜에 관련된 방법 및 조성물 |
| DK2714059T3 (en) | 2011-06-01 | 2019-01-21 | Celularity Inc | TREATMENT OF PAIN WHEN USING PLACENT STAM CELLS |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| CA2857545A1 (en) * | 2011-11-30 | 2013-06-06 | Advanced Cell Technology, Inc. | Mesenchymal stromal cells and uses related thereto |
| CN103191154B (zh) * | 2012-01-06 | 2015-09-09 | 上海交通大学医学院 | 充质干细胞及其提取方法在制备银屑病的药物中的应用 |
| WO2014098960A2 (en) * | 2012-05-16 | 2014-06-26 | The Johns Hopkins University | Stem cells as an individualized maternal therapy for prevention of prematurity |
| WO2014011407A2 (en) | 2012-07-12 | 2014-01-16 | Imstem Biotechnology, Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| CN115919901A (zh) * | 2012-12-12 | 2023-04-07 | 麦瑟布莱斯特公司 | 治疗或预防呼吸病症的方法 |
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| CN105769911A (zh) * | 2016-03-23 | 2016-07-20 | 中国人民解放军第二军医大学 | 间充质干细胞诱导斑秃处毛发再生的方法及应用 |
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| JP7105195B2 (ja) | 2016-11-15 | 2022-07-22 | 株式会社カネカ | 胎児付属物に由来する間葉系幹細胞を含む細胞集団とその製造方法、及び医薬組成物 |
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| US20210315937A1 (en) * | 2020-04-08 | 2021-10-14 | University Of South Florida | Methods of treating inflammation |
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| CN111568930A (zh) * | 2020-05-23 | 2020-08-25 | 湖南源品细胞生物科技有限公司 | 一种msc用于调节nk细胞数量的应用 |
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2007
- 2007-03-22 US US11/726,676 patent/US20080095749A1/en not_active Abandoned
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2008
- 2008-03-21 KR KR1020227042287A patent/KR20220166876A/ko not_active Ceased
- 2008-03-21 EP EP24190629.6A patent/EP4438721A3/en active Pending
- 2008-03-21 KR KR1020087025381A patent/KR20090122415A/ko not_active Ceased
- 2008-03-21 WO PCT/US2008/057828 patent/WO2008116157A2/en not_active Ceased
- 2008-03-21 US US12/091,370 patent/US20090220464A1/en not_active Abandoned
- 2008-03-21 JP JP2009554770A patent/JP2010522212A/ja active Pending
- 2008-03-21 KR KR1020197007767A patent/KR102357942B1/ko active Active
- 2008-03-21 CA CA3134185A patent/CA3134185A1/en active Pending
- 2008-03-21 CA CA2637157A patent/CA2637157C/en active Active
- 2008-03-21 ES ES21195085T patent/ES2988291T3/es active Active
- 2008-03-21 EP EP19204349.5A patent/EP3653217B1/en active Active
- 2008-03-21 KR KR1020247000248A patent/KR20240008404A/ko not_active Ceased
- 2008-03-21 CN CN200880000168A patent/CN101626772A/zh active Pending
- 2008-03-21 KR KR1020227002865A patent/KR102519603B1/ko active Active
- 2008-03-21 DK DK09009947.4T patent/DK2123747T3/en active
- 2008-03-21 BR BRPI0802241-0A patent/BRPI0802241A2/pt not_active Application Discontinuation
- 2008-03-21 EP EP08744188A patent/EP2051718A2/en not_active Withdrawn
- 2008-03-21 EP EP16171424.1A patent/EP3095450B1/en active Active
- 2008-03-21 ES ES19204349T patent/ES2891574T3/es active Active
- 2008-03-21 KR KR1020167004407A patent/KR20160027230A/ko not_active Ceased
- 2008-03-21 EP EP21195085.2A patent/EP3973970B1/en active Active
- 2008-03-21 ES ES16171424T patent/ES2765650T3/es active Active
- 2008-03-21 EP EP09009947.4A patent/EP2123747B1/en active Active
- 2008-03-21 KR KR1020257010916A patent/KR20250052468A/ko active Pending
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2010
- 2010-08-25 US US12/868,415 patent/US20100330048A1/en not_active Abandoned
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2014
- 2014-06-17 JP JP2014124452A patent/JP5961220B2/ja active Active