JP2017524732A5 - - Google Patents
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- Publication number
- JP2017524732A5 JP2017524732A5 JP2017519463A JP2017519463A JP2017524732A5 JP 2017524732 A5 JP2017524732 A5 JP 2017524732A5 JP 2017519463 A JP2017519463 A JP 2017519463A JP 2017519463 A JP2017519463 A JP 2017519463A JP 2017524732 A5 JP2017524732 A5 JP 2017524732A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- disease
- administered
- leukotoxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 30
- FBUKMFOXMZRGRB-UHFFFAOYSA-N Coronaric acid Natural products CCCCCC=CCC1OC1CCCCCCCC(O)=O FBUKMFOXMZRGRB-UHFFFAOYSA-N 0.000 claims 6
- 108090000695 Cytokines Proteins 0.000 claims 6
- 102000004127 Cytokines Human genes 0.000 claims 6
- 101710170970 Leukotoxin Proteins 0.000 claims 6
- 208000035473 Communicable disease Diseases 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 210000000265 leukocyte Anatomy 0.000 claims 4
- 206010061218 Inflammation Diseases 0.000 claims 3
- 206010035664 Pneumonia Diseases 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 230000004054 inflammatory process Effects 0.000 claims 3
- 210000004072 lung Anatomy 0.000 claims 3
- 208000017667 Chronic Disease Diseases 0.000 claims 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 2
- 201000003883 Cystic fibrosis Diseases 0.000 claims 2
- 101000998151 Homo sapiens Interleukin-17F Proteins 0.000 claims 2
- 102100033454 Interleukin-17F Human genes 0.000 claims 2
- 108090000978 Interleukin-4 Proteins 0.000 claims 2
- 108010002616 Interleukin-5 Proteins 0.000 claims 2
- 108010002335 Interleukin-9 Proteins 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 229940112141 dry powder inhaler Drugs 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 239000006199 nebulizer Substances 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 241000606749 Aggregatibacter actinomycetemcomitans Species 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 102100022339 Integrin alpha-L Human genes 0.000 claims 1
- 108010064548 Lymphocyte Function-Associated Antigen-1 Proteins 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 239000013566 allergen Substances 0.000 claims 1
- 230000007815 allergy Effects 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 229940071648 metered dose inhaler Drugs 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 230000001629 suppression Effects 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462014967P | 2014-06-20 | 2014-06-20 | |
| US62/014,967 | 2014-06-20 | ||
| PCT/US2015/036814 WO2015196159A1 (en) | 2014-06-20 | 2015-06-19 | Methods to treat inflammation of the lung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017524732A JP2017524732A (ja) | 2017-08-31 |
| JP2017524732A5 true JP2017524732A5 (cg-RX-API-DMAC7.html) | 2018-07-26 |
| JP6649376B2 JP6649376B2 (ja) | 2020-02-19 |
Family
ID=54868677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017519463A Active JP6649376B2 (ja) | 2014-06-20 | 2015-06-19 | 肺の炎症を治療する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9724384B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3157542B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6649376B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2952875C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015196159A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4054662B1 (en) * | 2019-11-08 | 2024-07-10 | Hollister Incorporated | Hydrophilic medical products and hydration mediums for hydrating the same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7199125B2 (en) * | 2003-10-02 | 2007-04-03 | Bristol-Myers Squibb Company | Spiro-cyclic compounds useful as anti-inflammatory agents |
| US8926990B2 (en) * | 2009-10-13 | 2015-01-06 | Rutgers, The State University Of New Jersey | Treatment and diagnosis of inflammatory disorders and HIV |
| WO2011047011A2 (en) * | 2009-10-13 | 2011-04-21 | University Of Medicine And Dentistry Of New Jersey | Treatment and diagnosis of inflammatory disorders |
| WO2007062150A2 (en) | 2005-11-25 | 2007-05-31 | University Of Medicine And Dentistry Of New Jersey | Leukotoxin compositions and therapeutic methods |
| US8053406B2 (en) | 2005-11-25 | 2011-11-08 | University Of Medicine And Dentistry Of New Jersey | Compositions for the treatment of cancer, and methods for testing and using the same |
| WO2012125942A1 (en) | 2011-03-16 | 2012-09-20 | University Of Medicine And Dentistry Of New Jersey | Combination therapy with leukotoxin |
| EP2265124A4 (en) * | 2008-04-15 | 2011-12-28 | Sarcode Bioscience Inc | AEROSOLISED LFA-1 ANTAGONISTS FOR THE USE IN THE LOCAL TREATMENT OF IMMUNE DISEASES |
| EP3013425B1 (en) * | 2013-06-27 | 2020-09-09 | Rutgers, the State University of New Jersey | Leukotoxin for use in the treatment of ocular disease |
-
2015
- 2015-06-19 EP EP15810310.1A patent/EP3157542B1/en active Active
- 2015-06-19 CA CA2952875A patent/CA2952875C/en active Active
- 2015-06-19 US US14/745,297 patent/US9724384B2/en active Active
- 2015-06-19 JP JP2017519463A patent/JP6649376B2/ja active Active
- 2015-06-19 WO PCT/US2015/036814 patent/WO2015196159A1/en not_active Ceased