JP2010514786A5 - - Google Patents
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- JP2010514786A5 JP2010514786A5 JP2009544215A JP2009544215A JP2010514786A5 JP 2010514786 A5 JP2010514786 A5 JP 2010514786A5 JP 2009544215 A JP2009544215 A JP 2009544215A JP 2009544215 A JP2009544215 A JP 2009544215A JP 2010514786 A5 JP2010514786 A5 JP 2010514786A5
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- JP
- Japan
- Prior art keywords
- group
- aryl
- alkyl
- heteroaryl
- nhr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- TUHOPGDFPMSKNY-VMDKLMDRSA-N C=C/C=C(\C=C/CCNC(N)=N)/OCCF Chemical compound C=C/C=C(\C=C/CCNC(N)=N)/OCCF TUHOPGDFPMSKNY-VMDKLMDRSA-N 0.000 description 1
- WGEYEADLUCMLOJ-FPLPWBNLSA-N NC(N/C=C(\C=C1)/C#CC(Cl)=C1OCCF)=N Chemical compound NC(N/C=C(\C=C1)/C#CC(Cl)=C1OCCF)=N WGEYEADLUCMLOJ-FPLPWBNLSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87721106P | 2006-12-26 | 2006-12-26 | |
| US60/877,211 | 2006-12-26 | ||
| PCT/US2007/088500 WO2008083056A2 (en) | 2006-12-26 | 2007-12-21 | Ligands for imaging cardiac innervation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014152244A Division JP6021860B2 (ja) | 2006-12-26 | 2014-07-25 | 心臓の神経支配を画像化するためのリガンド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010514786A JP2010514786A (ja) | 2010-05-06 |
| JP2010514786A5 true JP2010514786A5 (enExample) | 2011-02-24 |
| JP5656408B2 JP5656408B2 (ja) | 2015-01-21 |
Family
ID=39307501
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009544215A Active JP5656408B2 (ja) | 2006-12-26 | 2007-12-21 | 心臓の神経支配を画像化するためのリガンド |
| JP2014152244A Active JP6021860B2 (ja) | 2006-12-26 | 2014-07-25 | 心臓の神経支配を画像化するためのリガンド |
| JP2016085372A Pending JP2016183164A (ja) | 2006-12-26 | 2016-04-21 | 心臓の神経支配を画像化するためのリガンド |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014152244A Active JP6021860B2 (ja) | 2006-12-26 | 2014-07-25 | 心臓の神経支配を画像化するためのリガンド |
| JP2016085372A Pending JP2016183164A (ja) | 2006-12-26 | 2016-04-21 | 心臓の神経支配を画像化するためのリガンド |
Country Status (20)
| Country | Link |
|---|---|
| US (5) | US8491868B2 (enExample) |
| EP (5) | EP2114873B1 (enExample) |
| JP (3) | JP5656408B2 (enExample) |
| KR (4) | KR20170102580A (enExample) |
| CN (3) | CN101687780B (enExample) |
| AU (1) | AU2007339954B2 (enExample) |
| BR (1) | BRPI0722082A8 (enExample) |
| CA (2) | CA2984226C (enExample) |
| CO (1) | CO6231002A2 (enExample) |
| DK (3) | DK2474525T3 (enExample) |
| ES (3) | ES2805286T3 (enExample) |
| IL (3) | IL199563A (enExample) |
| MX (2) | MX2009007018A (enExample) |
| PL (1) | PL2114873T3 (enExample) |
| PT (1) | PT2114873E (enExample) |
| RU (1) | RU2506256C2 (enExample) |
| SG (1) | SG177918A1 (enExample) |
| TW (2) | TWI549692B (enExample) |
| WO (1) | WO2008083056A2 (enExample) |
| ZA (1) | ZA200904828B (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| EP2114873B1 (en) | 2006-12-26 | 2013-02-20 | Lantheus Medical Imaging, Inc. | N-[3-bromo-4-(3- [18f]fluoropropoxy)-benzyl]-guanidine for imaging cardiac innervation |
| US8936777B2 (en) | 2010-02-08 | 2015-01-20 | Lantheus Medical Imaging, Inc. | Methods and apparatus for synthesizing imaging agents, and intermediates thereof |
| WO2011143360A2 (en) * | 2010-05-11 | 2011-11-17 | Lantheus Medical Imaging, Inc. | Compositions, methods and systems for the synthesis and use of imaging agents |
| MX354217B (es) * | 2010-05-14 | 2018-02-19 | Dana Farber Cancer Inst Inc | Composiciones y metodos para el tratamiento de leucemia. |
| CA2799381A1 (en) | 2010-05-14 | 2011-11-17 | Dana-Farber Cancer Institute, Inc. | Male contraceptive compositions and methods of use |
| MX362384B (es) | 2010-05-14 | 2019-01-15 | Dana Farber Cancer Inst Inc | Composiciones y metodos para tratar neoplasias, enfermedades inflamatorias y otros trastornos. |
| AR086113A1 (es) | 2011-04-30 | 2013-11-20 | Abbott Lab | Isoxazolinas como agentes terapeuticos |
| EP2753605B1 (en) | 2011-09-09 | 2019-03-27 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| CA2869398C (en) | 2012-04-10 | 2019-10-22 | Lantheus Medical Imaging, Inc. | Radiopharmaceutical synthesis methods |
| AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| WO2014052454A1 (en) * | 2012-09-25 | 2014-04-03 | The Regents Of The University Of Michigan | Imaging agents |
| EP2948188B1 (en) * | 2013-01-24 | 2021-09-08 | Tylerton International Holdings Inc. | Neuronal imaging and treatment |
| WO2014115151A1 (en) * | 2013-01-24 | 2014-07-31 | Tylerton International Holdings Inc. | Body structure imaging |
| WO2014141247A1 (en) * | 2013-03-11 | 2014-09-18 | Tylerton International Holdings Inc. | Modeling the autonomous nervous system and uses thereof |
| KR20160034379A (ko) | 2013-07-25 | 2016-03-29 | 다나-파버 캔서 인스티튜트 인크. | 전사 인자의 억제제 및 그의 용도 |
| US10052495B2 (en) | 2013-09-08 | 2018-08-21 | Tylerton International Inc. | Detection of reduced-control cardiac zones |
| WO2015070020A2 (en) | 2013-11-08 | 2015-05-14 | Dana-Farber Cancer Institute, Inc. | Combination therapy for cancer using bromodomain and extra-terminal (bet) protein inhibitors |
| CN106102583B (zh) | 2014-01-10 | 2024-08-09 | 泰勒顿国际控股公司 | 瘢痕和纤维心脏区的检测 |
| WO2015117087A1 (en) | 2014-01-31 | 2015-08-06 | Dana-Farber Cancer Institute, Inc. | Uses of diazepane derivatives |
| RU2016134947A (ru) | 2014-01-31 | 2018-03-01 | Дана-Фарбер Кансер Институт, Инк. | Производные диаминопиримидин бензолсульфона и их применение |
| AU2015222805B2 (en) | 2014-02-28 | 2020-05-21 | Tensha Therapeutics, Inc. | Treatment of conditions associated with hyperinsulinaemia |
| EP3174466B1 (en) | 2014-07-30 | 2020-06-17 | Navix International Limited | Probe localization |
| BR112017002190A2 (pt) | 2014-08-08 | 2017-11-21 | Dana Farber Cancer Inst Inc | derivados de di-hidropteridinona e usos dos mesmos |
| EP3177626A4 (en) | 2014-08-08 | 2017-12-27 | Dana Farber Cancer Institute, Inc. | Diazepane derivatives and uses thereof |
| AU2016276963C1 (en) | 2015-06-12 | 2021-08-05 | Dana-Farber Cancer Institute, Inc. | Combination therapy of transcription inhibitors and kinase inhibitors |
| US10881668B2 (en) | 2015-09-11 | 2021-01-05 | Dana-Farber Cancer Institute, Inc. | Acetamide thienotriazolodiazepines and uses thereof |
| CN108472300A (zh) | 2015-09-11 | 2018-08-31 | 达纳-法伯癌症研究所股份有限公司 | 氰基噻吩并三唑并二氮杂环庚三烯及其用途 |
| MX2018006499A (es) | 2015-11-25 | 2018-08-01 | Dana Farber Cancer Inst Inc | Inhibidores de bromodominio bivalentes y usos de los mismos. |
| CN107892651A (zh) * | 2017-11-29 | 2018-04-10 | 陕西慧康生物科技有限责任公司 | 一种合成dl‑盐酸麻黄碱的方法 |
| EP3866692B1 (en) * | 2018-10-15 | 2025-07-23 | Bristol-Myers Squibb Company | Radioligands for imaging the lpa1 receptor |
| EP3682906A1 (en) | 2019-01-17 | 2020-07-22 | Julius-Maximilians-Universität Würzburg | Compound targeting norepinephrine transporter |
| CN109748825B (zh) * | 2019-02-01 | 2022-02-18 | 原子高科股份有限公司 | 一种18f标记的胍甲基取代苯类似物及其应用 |
| KR102690858B1 (ko) | 2020-07-14 | 2024-08-02 | 한국과학기술원 | 이산화탄소와 개미산만으로 성장 가능한 재조합 미생물 및 상기 재조합 미생물을 이용하여 유용물질을 제조하는 방법 |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6012A (en) * | 1849-01-09 | Lithographing co | ||
| FR1010218A (fr) | 1949-02-10 | 1952-06-09 | American Cyanamid Co | Perfectionnements aux sels de guanidine |
| GB1215255A (en) | 1968-03-13 | 1970-12-09 | Pfizer & Co C | Halophenylalkylguanidine compounds |
| US4094881A (en) | 1976-03-10 | 1978-06-13 | Smithkline Corporation | Process for preparing triazolethiols |
| US4275074A (en) | 1979-03-09 | 1981-06-23 | Graham J. Dobbie | Catecholamine treatment of ocular hypertension |
| US4270537A (en) | 1979-11-19 | 1981-06-02 | Romaine Richard A | Automatic hypodermic syringe |
| US4258188A (en) * | 1980-02-04 | 1981-03-24 | American Home Products Corporation | 2-(1-Piperazinyl)-cycloheptimidazole derivatives |
| US4622217A (en) * | 1984-04-27 | 1986-11-11 | The Regents Of The University Of Michigan | I-4-amino-3-iodobenzylguanidine as imaging and therapeutic agent |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| US4886499A (en) | 1986-12-18 | 1989-12-12 | Hoffmann-La Roche Inc. | Portable injection appliance |
| GB8704027D0 (en) | 1987-02-20 | 1987-03-25 | Owen Mumford Ltd | Syringe needle combination |
| AU1503888A (en) * | 1987-04-24 | 1988-10-27 | King Faisal Specialist Hospital & Research Centre | Method of producing iodine124 and meta-iodobenzlyguanidine containing iodine124 |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| US4940460A (en) | 1987-06-19 | 1990-07-10 | Bioject, Inc. | Patient-fillable and non-invasive hypodermic injection device assembly |
| US5339163A (en) | 1988-03-16 | 1994-08-16 | Canon Kabushiki Kaisha | Automatic exposure control device using plural image plane detection areas |
| FR2638359A1 (fr) | 1988-11-03 | 1990-05-04 | Tino Dalto | Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5190521A (en) | 1990-08-22 | 1993-03-02 | Tecnol Medical Products, Inc. | Apparatus and method for raising a skin wheal and anesthetizing skin |
| US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
| GB9118204D0 (en) | 1991-08-23 | 1991-10-09 | Weston Terence E | Needle-less injector |
| SE9102652D0 (sv) | 1991-09-13 | 1991-09-13 | Kabi Pharmacia Ab | Injection needle arrangement |
| US5663166A (en) * | 1991-10-18 | 1997-09-02 | Genentech, Inc. | Nonpeptidyl integrin inhibitors having specificity for the GPIIb IIIa receptor |
| US5328483A (en) | 1992-02-27 | 1994-07-12 | Jacoby Richard M | Intradermal injection device with medication and needle guard |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| US5334144A (en) | 1992-10-30 | 1994-08-02 | Becton, Dickinson And Company | Single use disposable needleless injector |
| TW279864B (enExample) * | 1993-02-19 | 1996-07-01 | Janssen Pharmaceutica Nv | |
| US5879657A (en) * | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
| EP0639573A1 (de) * | 1993-08-03 | 1995-02-22 | Hoechst Aktiengesellschaft | Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament |
| WO1995024176A1 (en) | 1994-03-07 | 1995-09-14 | Bioject, Inc. | Ampule filling device |
| US5466220A (en) | 1994-03-08 | 1995-11-14 | Bioject, Inc. | Drug vial mixing and transfer device |
| US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
| US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
| AU703340B2 (en) | 1995-06-26 | 1999-03-25 | Chelator Llc | Compounds with chelation affinity and selectivity for first transition series elements, and their use in medical therapy and diagnosis |
| US5893397A (en) | 1996-01-12 | 1999-04-13 | Bioject Inc. | Medication vial/syringe liquid-transfer apparatus |
| GB9607549D0 (en) | 1996-04-11 | 1996-06-12 | Weston Medical Ltd | Spring-powered dispensing device |
| TW499412B (en) | 1996-11-26 | 2002-08-21 | Dimensional Pharm Inc | Aminoguanidines and alkoxyguanidines as protease inhibitors |
| JP2001527527A (ja) | 1996-11-27 | 2001-12-25 | デュポン ファーマシューティカルズ カンパニー | 新規インテグリン受容体拮抗薬 |
| US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
| WO1999018053A1 (en) | 1997-10-02 | 1999-04-15 | The University Of Western Ontario | Preparation of radiolabelled haloaromatics via polymer-bound intermediates |
| IT1298087B1 (it) | 1998-01-08 | 1999-12-20 | Fiderm S R L | Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni |
| AU3406599A (en) | 1998-04-09 | 1999-11-01 | Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat Berlin | Novel benzyl guanidine derivatives for therapy and (in-vivo) and (in-vitro) diagnosis |
| WO2000009115A1 (en) | 1998-08-14 | 2000-02-24 | Smithkline Beecham Corporation | Grp receptor ligands |
| EP1140204A2 (en) | 1998-12-18 | 2001-10-10 | Du Pont Pharmaceuticals Company | Vitronectin receptor antagonist pharmaceuticals |
| US6656448B1 (en) | 2000-02-15 | 2003-12-02 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| GB0019357D0 (en) | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel phenyl guanidines |
| DE10114561A1 (de) | 2001-03-24 | 2002-09-26 | Wella Ag | Verwendung von Mitteln enthaltend Kreatin, Kreatin und/oder deren Derivaten zur Verstärkung und Strukturverbesserung von keratinischen Fasern |
| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| WO2004018465A2 (en) | 2002-08-17 | 2004-03-04 | Altana Pharma Ag | Benzonaphthyridines with pde 3/4 inhibiting activity |
| WO2004037166A2 (en) | 2002-09-17 | 2004-05-06 | Isis Pharmaceuticals, Inc. | Therapeutic guanidines |
| US7754188B2 (en) * | 2003-06-30 | 2010-07-13 | Merck Sharp & Dohme Corp. | Radiolabeled cannabinoid-1 receptor modulators |
| EP1691777A4 (en) * | 2003-12-01 | 2010-10-13 | Medi Physics Inc | NEW DIFFERENTIAL IMAGING METHOD |
| WO2005095345A2 (en) * | 2004-03-23 | 2005-10-13 | Achillion Pharmaceuticals, Inc. | Heteroaryl guanidines as inhibitors of viral replication |
| US9388122B2 (en) | 2004-05-28 | 2016-07-12 | Hamamatsu Photonics K.K. | Radioactive tyrosine derivative, method for producing same, labeling agent for positron imaging and medical agent for assessing grade of malignancy of tumor respectively composed of radioactive tyrosine derivative, and method for detecting tumor |
| ATE493152T1 (de) | 2004-09-23 | 2011-01-15 | Guerbet Sa | Liposomale kontrastmittel für die cest-bildgebung |
| US20060083681A1 (en) * | 2004-10-18 | 2006-04-20 | Ajay Purohit | Compounds for myocardial perfusion imaging |
| US7534418B2 (en) * | 2004-12-10 | 2009-05-19 | The Regents Of The University Of Michigan | Imaging agents |
| GB0512770D0 (en) | 2005-06-23 | 2005-07-27 | Hammersmith Imanet Ltd | Imaging compounds |
| MX2009005920A (es) | 2006-12-13 | 2009-06-16 | Hoffmann La Roche | Nuevos 2-imidazoles como ligandos para receptores asociados con trazas de amina. |
| GB0625523D0 (en) | 2006-12-21 | 2007-01-31 | Ge Healthcare Ltd | In vivo imaging agents |
| EP2114873B1 (en) * | 2006-12-26 | 2013-02-20 | Lantheus Medical Imaging, Inc. | N-[3-bromo-4-(3- [18f]fluoropropoxy)-benzyl]-guanidine for imaging cardiac innervation |
| WO2008082305A1 (en) | 2006-12-28 | 2008-07-10 | Raufoss Technology As | Control arm |
| WO2008115593A1 (en) | 2007-03-21 | 2008-09-25 | The University Of Montana | 1-[(2'-substituted)-piperazin-1'-yl]-isoquinolines as norepinephrine transporter inhibitor therapeutics and positron emission tomography imaging agents |
| KR20100095528A (ko) | 2007-10-18 | 2010-08-31 | 베링거 인겔하임 인터내셔날 게엠베하 | 디하이드로티에노[3,2-ｄ]피리미딘의 제조방법 및 상기 제조방법에서 사용된 중간체 |
| WO2010015340A1 (en) | 2008-08-06 | 2010-02-11 | Bayer Schering Pharma Aktiengesellschaft | Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment |
| GB0906274D0 (en) | 2009-04-09 | 2009-05-20 | Ge Healthcare Ltd | Imaging the central nervous system |
| CA2758883C (en) | 2009-04-15 | 2020-03-10 | Lantheus Medical Imaging, Inc. | Stabilization of radiopharmaceutical compositions using ascorbic acid |
| CN101555232B (zh) | 2009-05-21 | 2011-01-05 | 北京师范大学 | 氟-18标记哒嗪酮类化合物及制备方法和应用 |
| JP5676600B2 (ja) | 2009-07-08 | 2015-02-25 | ランセウス メディカル イメージング， インコーポレイテッド | 造影剤としてのｎ−アルコキシアミド抱合体 |
| US8936777B2 (en) | 2010-02-08 | 2015-01-20 | Lantheus Medical Imaging, Inc. | Methods and apparatus for synthesizing imaging agents, and intermediates thereof |
| WO2011143360A2 (en) | 2010-05-11 | 2011-11-17 | Lantheus Medical Imaging, Inc. | Compositions, methods and systems for the synthesis and use of imaging agents |
| EP2753605B1 (en) | 2011-09-09 | 2019-03-27 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| EP2671575A1 (en) | 2012-06-04 | 2013-12-11 | Universität Regensburg | Ras inhibitors |
| JP2017131851A (ja) | 2016-01-29 | 2017-08-03 | 日本特殊陶業株式会社 | マイクロ波加熱用触媒材料、マイクロ波加熱用触媒体、及び、その製造方法 |
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2007
- 2007-12-21 EP EP07869717A patent/EP2114873B1/en active Active
- 2007-12-21 MX MX2009007018A patent/MX2009007018A/es active IP Right Grant
- 2007-12-21 TW TW096149600A patent/TWI549692B/zh not_active IP Right Cessation
- 2007-12-21 EP EP12152817.8A patent/EP2474525B1/en active Active
- 2007-12-21 EP EP12152816A patent/EP2474524A3/en active Pending
- 2007-12-21 ES ES12152817T patent/ES2805286T3/es active Active
- 2007-12-21 KR KR1020177024416A patent/KR20170102580A/ko not_active Ceased
- 2007-12-21 MX MX2014010520A patent/MX367292B/es unknown
- 2007-12-21 KR KR1020097015613A patent/KR101718160B1/ko not_active Expired - Fee Related
- 2007-12-21 EP EP12152815.2A patent/EP2474523B1/en active Active
- 2007-12-21 PT PT78697174T patent/PT2114873E/pt unknown
- 2007-12-21 ES ES07869717T patent/ES2405655T3/es active Active
- 2007-12-21 JP JP2009544215A patent/JP5656408B2/ja active Active
- 2007-12-21 KR KR1020167010430A patent/KR101810348B1/ko not_active Expired - Fee Related
- 2007-12-21 RU RU2009128591/04A patent/RU2506256C2/ru active
- 2007-12-21 EP EP12152818A patent/EP2474526A3/en not_active Withdrawn
- 2007-12-21 ES ES12152815T patent/ES2804801T3/es active Active
- 2007-12-21 AU AU2007339954A patent/AU2007339954B2/en active Active
- 2007-12-21 US US12/448,575 patent/US8491868B2/en active Active
- 2007-12-21 CA CA2984226A patent/CA2984226C/en active Active
- 2007-12-21 KR KR1020147032350A patent/KR20140140134A/ko not_active Ceased
- 2007-12-21 BR BRPI0722082A patent/BRPI0722082A8/pt not_active Application Discontinuation
- 2007-12-21 CN CN200780051773.0A patent/CN101687780B/zh not_active Expired - Fee Related
- 2007-12-21 TW TW105113601A patent/TWI618544B/zh not_active IP Right Cessation
- 2007-12-21 DK DK12152817.8T patent/DK2474525T3/da active
- 2007-12-21 DK DK12152815.2T patent/DK2474523T3/da active
- 2007-12-21 WO PCT/US2007/088500 patent/WO2008083056A2/en not_active Ceased
- 2007-12-21 CN CN201510856954.7A patent/CN105622463B/zh not_active Expired - Fee Related
- 2007-12-21 CN CN201910053427.0A patent/CN110003079A/zh active Pending
- 2007-12-21 CA CA2673853A patent/CA2673853C/en active Active
- 2007-12-21 DK DK07869717.4T patent/DK2114873T3/da active
- 2007-12-21 SG SG2011095601A patent/SG177918A1/en unknown
- 2007-12-21 PL PL07869717T patent/PL2114873T3/pl unknown
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2009
- 2009-06-25 IL IL199563A patent/IL199563A/en active IP Right Grant
- 2009-07-09 ZA ZA2009/04828A patent/ZA200904828B/en unknown
- 2009-07-22 CO CO09076173A patent/CO6231002A2/es active IP Right Grant
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2013
- 2013-01-24 IL IL224396A patent/IL224396B/en active IP Right Grant
- 2013-06-12 US US13/916,205 patent/US10010631B2/en active Active
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2014
- 2014-07-25 JP JP2014152244A patent/JP6021860B2/ja active Active
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2016
- 2016-04-21 JP JP2016085372A patent/JP2016183164A/ja active Pending
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2017
- 2017-08-07 IL IL253885A patent/IL253885A0/en unknown
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2018
- 2018-05-22 US US15/986,680 patent/US11241509B2/en active Active
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2022
- 2022-01-28 US US17/587,454 patent/US12324845B2/en active Active
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2025
- 2025-01-17 US US19/027,961 patent/US20250161500A1/en active Pending