|
US2802005A
(en)
|
|
1957-08-06 |
|
S-eluorourace |
|
US1973A
(en)
|
|
1841-02-10 |
|
Method oe cowstettctiitg clocks |
|
US2512572A
(en)
|
|
1950-06-20 |
|
Substituted pteridines and method |
|
US2917432A
(en)
|
1954-10-05 |
1959-12-15 |
Burroughs Wellcome Co |
Leukemia treatment
|
|
US2848455A
(en)
|
1955-07-18 |
1958-08-19 |
Ciba Pharm Prod Inc |
Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
|
|
US2891079A
(en)
|
1959-01-23 |
1959-06-16 |
Searle & Co |
6-methyl-4, 6-pregnadiene-3, 20-dione and 17alpha-acyloxy derivatives thereof
|
|
US3046301A
(en)
|
1959-10-29 |
1962-07-24 |
Burroughs Wellcome Co |
Method of making chlorambucil
|
|
US3116282A
(en)
|
1960-04-27 |
1963-12-31 |
Upjohn Co |
Pyrimidine nucleosides and process
|
|
BE637389A
(enExample)
|
1962-09-13 |
|
|
|
|
US3432549A
(en)
|
1965-04-22 |
1969-03-11 |
Egyt Gyogyszervegyeszeti Gyar |
Pharmacologically active new substituted benzamides
|
|
US3732340A
(en)
|
1966-07-11 |
1973-05-08 |
Asta Werke Ag Chem Fab |
N',o-propylene phosphoric acid ester diamides
|
|
US3803124A
(en)
|
1968-04-12 |
1974-04-09 |
Farmaceutici It Soc |
Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
|
|
CH527207A
(de)
|
1968-05-08 |
1972-08-31 |
Ceskoslovenska Akademie Ved |
Verfahren zur Herstellung von 1-Glycosyl-5-azacytosinen
|
|
GB1235022A
(en)
|
1969-06-04 |
1971-06-09 |
Laeaeke Ag |
A new method for the production of cyclophosphamide
|
|
CH526500A
(de)
|
1969-12-31 |
1972-08-15 |
Hoffmann La Roche |
Verfahren zur Herstellung von Polyenverbindungen
|
|
DE2124023C3
(de)
|
1970-05-27 |
1980-07-10 |
Richter Gedeon Vegyeszeti Gyar R.T., Budapest |
Verfahren zur selektiven Gewinnung von Vinblastin, Vinleurosin und Vincristin oder von deren Sulfaten
|
|
GB1354939A
(en)
|
1971-10-28 |
1974-06-05 |
Ici Ltd |
Process for the manufacture of 1,1,2-triphenylalk-1-enes
|
|
JPS4910506A
(enExample)
|
1972-05-31 |
1974-01-30 |
|
|
|
CH605550A5
(enExample)
|
1972-06-08 |
1978-09-29 |
Research Corp |
|
|
AR204004A1
(es)
|
1973-04-02 |
1975-11-12 |
Lilly Co Eli |
Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
|
|
US3914412A
(en)
|
1973-10-11 |
1975-10-21 |
Abbott Lab |
{8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity
|
|
US4005063A
(en)
|
1973-10-11 |
1977-01-25 |
Abbott Laboratories |
[Des-gly]10 -GnRH nonapeptide anide analogs in position 6 having ovulation-inducing activity
|
|
GB1457632A
(en)
|
1974-03-22 |
1976-12-08 |
Farmaceutici Italia |
Adriamycins
|
|
US4020270A
(en)
|
1974-05-02 |
1977-04-26 |
Societa' Farmaceutici Italia S.P.A. |
L-lyxohex-1-enopyranose derivative
|
|
GB1467383A
(en)
|
1974-06-12 |
1977-03-16 |
Farmaceutici Italia |
Daunomycin analogues
|
|
DE2438350C3
(de)
|
1974-08-09 |
1979-06-13 |
Hoechst Ag, 6000 Frankfurt |
Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
|
|
GB1524747A
(en)
|
1976-05-11 |
1978-09-13 |
Ici Ltd |
Polypeptide
|
|
JPS6041077B2
(ja)
|
1976-09-06 |
1985-09-13 |
喜徳 喜谷 |
1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体
|
|
US4197249A
(en)
|
1977-08-15 |
1980-04-08 |
American Cyanamid Company |
1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
|
|
US4307100A
(en)
|
1978-08-24 |
1981-12-22 |
Agence Nationale De Valorisation De La Recherche (Anvar) |
Nor bis-indole compounds usable as medicaments
|
|
DE2845574A1
(de)
|
1978-10-19 |
1980-04-24 |
Deutsches Krebsforsch |
Durch heterocyclische ringe oder alkylreste substituierte analoga von ccnu und verfahren zu deren herstellung
|
|
DE3046719C2
(de)
|
1980-12-11 |
1983-02-17 |
Klinge Pharma GmbH, 8000 München |
1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
|
|
US4357324A
(en)
|
1981-02-24 |
1982-11-02 |
The United States Of America As Represented By The Department Of Health And Human Services |
Prodrug derivatives of 9β-D-arabinofuranosyl-2-fluoroadenine
|
|
US4418068A
(en)
|
1981-04-03 |
1983-11-29 |
Eli Lilly And Company |
Antiestrogenic and antiandrugenic benzothiophenes
|
|
OA07174A
(fr)
|
1981-08-24 |
1984-04-30 |
May & Baker Ltd |
Nouvelles imidazotétrazionones, leur préparation et les médicaments qui les contiennent.
|
|
GB2126576B
(en)
|
1982-06-25 |
1985-06-19 |
Farmos Group Limited |
Alkane and alkene derivatives
|
|
DE3372965D1
(en)
|
1982-07-23 |
1987-09-17 |
Ici Plc |
Amide derivatives
|
|
EP0111058B1
(en)
|
1982-11-26 |
1987-11-04 |
Nippon Kayaku Kabushiki Kaisha |
Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
|
|
US4526988A
(en)
|
1983-03-10 |
1985-07-02 |
Eli Lilly And Company |
Difluoro antivirals and intermediate therefor
|
|
JPS6019790A
(ja)
|
1983-07-14 |
1985-01-31 |
Yakult Honsha Co Ltd |
新規なカンプトテシン誘導体
|
|
GB8327256D0
(en)
|
1983-10-12 |
1983-11-16 |
Ici Plc |
Steroid derivatives
|
|
US4582909A
(en)
*
|
1984-02-02 |
1986-04-15 |
Warner-Lambert Company |
Benzobicyclic lactam acids and derivatives as cognition activators
|
|
US4666828A
(en)
|
1984-08-15 |
1987-05-19 |
The General Hospital Corporation |
Test for Huntington's disease
|
|
US4760064A
(en)
|
1984-12-18 |
1988-07-26 |
Otsuka Pharmaceutical Co., Ltd. |
Carbostyril compounds, compositions containing same and processes for preparing same
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US5003011A
(en)
|
1985-04-09 |
1991-03-26 |
The Administrators Of The Tulane Educational Fund |
Therapeutic decapeptides
|
|
US4801531A
(en)
|
1985-04-17 |
1989-01-31 |
Biotechnology Research Partners, Ltd. |
Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
|
|
US4691918A
(en)
|
1985-10-08 |
1987-09-08 |
Diversified Products Corporation |
Multiple exercise device
|
|
US4978672A
(en)
|
1986-03-07 |
1990-12-18 |
Ciba-Geigy Corporation |
Alpha-heterocyclc substituted tolunitriles
|
|
JPS62220196A
(ja)
|
1986-03-20 |
1987-09-28 |
Kyowa Hakko Kogyo Co Ltd |
新規物質ucn―01
|
|
IN164232B
(enExample)
|
1986-04-11 |
1989-02-04 |
Hoechst India |
|
|
FR2601676B1
(fr)
|
1986-07-17 |
1988-09-23 |
Rhone Poulenc Sante |
Procede de preparation du taxol et du desacetyl-10 taxol
|
|
FR2601675B1
(fr)
|
1986-07-17 |
1988-09-23 |
Rhone Poulenc Sante |
Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
NZ224714A
(en)
|
1987-06-01 |
1990-03-27 |
Janssen Pharmaceutica Nv |
Substituted benzotriazole derivatives and pharmaceutical compositions
|
|
GB8714013D0
(en)
|
1987-06-16 |
1987-07-22 |
Ici Plc |
(substituted-aralkyl)heterocyclic compounds
|
|
US5004758A
(en)
|
1987-12-01 |
1991-04-02 |
Smithkline Beecham Corporation |
Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
|
|
CA1340191C
(en)
|
1988-06-13 |
1998-12-15 |
Katsuhiro Imaki |
Derivatives of p-substituted phenyl ester of pivalic acid
|
|
US4990511A
(en)
|
1988-08-03 |
1991-02-05 |
Takeda Chemical Industries, Ltd. |
Amide compounds, their production and use
|
|
US5272057A
(en)
|
1988-10-14 |
1993-12-21 |
Georgetown University |
Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
|
|
US5192659A
(en)
|
1989-08-25 |
1993-03-09 |
Genetype Ag |
Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
|
|
GB8926560D0
(en)
|
1989-11-24 |
1990-01-17 |
Zambeletti Spa L |
Pharmaceuticals
|
|
IL96531A
(en)
|
1989-12-11 |
1995-08-31 |
Univ Princeton |
History of Acid N- (Diomeric-H1-Pyrolo] D-2,3 [Pyrimidine-3-Ilacyl (-glutamic, preparation and pharmaceutical preparations containing them)
|
|
US5124350A
(en)
|
1990-06-28 |
1992-06-23 |
G. D. Searle & Co. |
Leukotriene b4 antagonists
|
|
US5177064A
(en)
|
1990-07-13 |
1993-01-05 |
University Of Florida |
Targeted drug delivery via phosphonate derivatives
|
|
CA2049481A1
(en)
|
1990-08-27 |
1992-02-28 |
Jill Ann Panetta |
Method of treating inflammatory bowel disease
|
|
TW295589B
(enExample)
|
1990-08-30 |
1997-01-11 |
Hoechst Ag |
|
|
FR2669029B1
(fr)
|
1990-11-14 |
1994-09-02 |
Adir |
Nouveaux derives de la n-benzoyl proline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
|
MX9102128A
(es)
|
1990-11-23 |
1992-07-08 |
Rhone Poulenc Rorer Sa |
Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
|
|
US5280046A
(en)
|
1991-02-22 |
1994-01-18 |
The University Of Colorado Foundation, Inc. |
Method of treating type I diabetes
|
|
WO1992017467A1
(en)
|
1991-04-06 |
1992-10-15 |
Dr Lo. Zambeletti S.P.A. |
Substituted azacyclic compounds, process for their preparation and their use as analgesics
|
|
GB9112859D0
(en)
|
1991-06-14 |
1991-07-31 |
Ici Plc |
Peptide process
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
IT1250692B
(it)
|
1991-07-23 |
1995-04-21 |
|
Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi.
|
|
TW225528B
(enExample)
|
1992-04-03 |
1994-06-21 |
Ciba Geigy Ag |
|
|
DE69333894D1
(de)
|
1992-04-22 |
2005-12-01 |
Ligand Pharm Inc |
Verbindungen mit Retinoid x rezeptorselektivität
|
|
DE4222910A1
(de)
|
1992-07-11 |
1994-01-13 |
Asta Medica Ag |
Neue Phospholipidderivate
|
|
KR100335584B1
(ko)
|
1992-10-28 |
2002-11-29 |
제넨테크, 인코포레이티드 |
혈관내피세포성장인자에대한길항제
|
|
ATE139900T1
(de)
|
1992-11-13 |
1996-07-15 |
Idec Pharma Corp |
Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma
|
|
US5466861A
(en)
|
1992-11-25 |
1995-11-14 |
Sri International |
Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
|
|
US5595721A
(en)
|
1993-09-16 |
1997-01-21 |
Coulter Pharmaceutical, Inc. |
Radioimmunotherapy of lymphoma using anti-CD20
|
|
CA2277954A1
(en)
|
1993-11-30 |
1995-06-08 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
|
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
|
US5476932A
(en)
|
1994-08-26 |
1995-12-19 |
Hoffmann-La Roche Inc. |
Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives
|
|
US6083903A
(en)
|
1994-10-28 |
2000-07-04 |
Leukosite, Inc. |
Boronic ester and acid compounds, synthesis and uses
|
|
US5633283A
(en)
|
1995-01-23 |
1997-05-27 |
Eli Lilly And Company |
Method for treating multiple sclerosis
|
|
ATE446955T1
(de)
|
1995-03-30 |
2009-11-15 |
Pfizer Prod Inc |
Chinazolinone derivate
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US5843901A
(en)
|
1995-06-07 |
1998-12-01 |
Advanced Research & Technology Institute |
LHRH antagonist peptides
|
|
CA2222231A1
(en)
|
1995-06-07 |
1996-12-19 |
Imclone Systems Incorporated |
Antibody and antibody fragments for inhibiting the growth of tumors
|
|
US6218529B1
(en)
|
1995-07-31 |
2001-04-17 |
Urocor, Inc. |
Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer
|
|
US5663357A
(en)
|
1995-11-22 |
1997-09-02 |
Allergan |
Substituted heteroarylamides having retinoid-like biological activity
|
|
US5675024A
(en)
|
1995-11-22 |
1997-10-07 |
Allergan |
Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity
|
|
FR2741881B1
(fr)
|
1995-12-01 |
1999-07-30 |
Centre Nat Rech Scient |
Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
|
|
JP3855026B2
(ja)
|
1996-01-16 |
2006-12-06 |
富士レビオ株式会社 |
アミド誘導体の製造方法
|
|
ATE478672T1
(de)
|
1996-01-29 |
2010-09-15 |
Univ California |
Methode zur behandlung sexueller fehlfunktionen
|
|
GB9606187D0
(en)
|
1996-03-23 |
1996-05-29 |
Inst Of Food Research |
Production of vanillin
|
|
CA2249615A1
(en)
|
1996-04-03 |
1997-10-09 |
Robert Gomez |
Inhibitors of farnesyl-protein transferase
|
|
EP0918518A4
(en)
|
1996-04-19 |
2002-05-02 |
Univ California |
TREATMENT OF MIND AND MOOD DISEASES WITH GLUTAMATERGIC MODULATORS.
|
|
IL118657A0
(en)
|
1996-06-14 |
1996-10-16 |
Arad Dorit |
Inhibitors for picornavirus proteases
|
|
DE69728986T2
(de)
|
1996-06-21 |
2005-04-07 |
Allergan, Inc., Irvine |
Substituierte tetrahydronaphthalin- und dihydronaphthalin-derivate mit einer retinoiden und/oder retinoid antagonist-ähnlichen biologischen aktivität
|
|
CA2744096C
(en)
|
1996-07-31 |
2013-07-30 |
Laboratory Corporation Of America Holdings |
Biomarkers and targets for diagnosis, prognosis and management of prostate disease
|
|
US5723632A
(en)
|
1996-08-08 |
1998-03-03 |
Mgi Pharma, Inc. |
Total synthesis of antitumor acylfulvenes
|
|
EP0827742A1
(en)
|
1996-09-04 |
1998-03-11 |
Vrije Universiteit Brussel |
Use of histone deacetylase inhibitors for treating fribosis or cirrhosis
|
|
ES2301194T3
(es)
|
1997-02-05 |
2008-06-16 |
Warner-Lambert Company Llc |
Pirido 2,3-d pirimidinas y 4-aminopirimidinas como inhibidores de la proliferacion celular.
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
EP0973778A1
(en)
|
1997-03-07 |
2000-01-26 |
Novo Nordisk A/S |
4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE
|
|
UY24949A1
(es)
|
1997-04-08 |
2001-04-30 |
Smithkline Beecham Corp |
Compuestos calcilíticos
|
|
US6159979A
(en)
|
1997-04-18 |
2000-12-12 |
Smithkline Beecham P.L.C. |
Bicyclic aryl or a bicyclic heterocyclic ring containing compounds having a combined 5HT1A, 5HT1B and 5HT1D receptor antagonistic activity
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US6329368B1
(en)
|
1997-05-09 |
2001-12-11 |
The Regents Of The University Of California |
Endocrine modulation with positive modulators of AMPA type glutamate receptors
|
|
GB9719426D0
(en)
|
1997-09-13 |
1997-11-12 |
Johnson Matthey Plc |
Novel process
|
|
US6166008A
(en)
|
1997-10-27 |
2000-12-26 |
Cortex Pharmaceuticals, Inc. |
Treatment of schizophrenia with ampakines and neuroleptics
|
|
AU1804299A
(en)
|
1997-12-08 |
1999-06-28 |
Glycomed Incorporated |
Sialyl lewis x and sialyl lewis a glycomimetics
|
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
EP1140840B1
(en)
|
1999-01-13 |
2006-03-22 |
Bayer Pharmaceuticals Corp. |
-g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
EP1165492A1
(en)
|
1999-03-30 |
2002-01-02 |
Pharmacor Inc. |
Hydroxyphenyl derivatives with hiv integrase inhibitory properties
|
|
CA2366932C
(en)
|
1999-04-15 |
2009-08-25 |
Bristol-Myers Squibb Company |
Cyclic protein tyrosine kinase inhibitors
|
|
US6166244A
(en)
|
1999-05-07 |
2000-12-26 |
Allergan Sales, Inc. |
Oxygen, sulfur and nitrogen substituted cyclohexene and cyclohexane derivatives having retinoid-like biological activity
|
|
US6127382A
(en)
|
1999-08-16 |
2000-10-03 |
Allergan Sales, Inc. |
Amines substituted with a tetrahydroquinolinyl group an aryl or heteroaryl group and an alkyl group, having retinoid-like biological activity
|
|
US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
|
EP1226129B1
(en)
|
1999-10-27 |
2006-05-24 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
|
PT1244647E
(pt)
|
1999-11-05 |
2006-10-31 |
Astrazeneca Ab |
Derivados de quinazolina como inibidores de vegf
|
|
DE19955283A1
(de)
|
1999-11-17 |
2001-05-23 |
Aventis Res & Tech Gmbh & Co |
Verfahren zur enantioselektiven Gewinnung von Aminosäuren und Aminosäurederivaten unter Verwendung von Racemisierungskatalysatoren
|
|
WO2001036351A2
(en)
|
1999-11-19 |
2001-05-25 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists related applications
|
|
MY125768A
(en)
|
1999-12-15 |
2006-08-30 |
Bristol Myers Squibb Co |
N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases
|
|
YU54202A
(sh)
|
2000-01-18 |
2006-01-16 |
Agouron Pharmaceuticals Inc. |
Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
|
|
HN2001000008A
(es)
|
2000-01-21 |
2003-12-11 |
Inc Agouron Pharmaceuticals |
Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
|
|
AU2001243158A1
(en)
|
2000-02-18 |
2001-08-27 |
Merck And Co., Inc. |
Inhibitors of prenyl-protein transferase
|
|
AU2001240658A1
(en)
|
2000-02-29 |
2001-09-12 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibitor combinations with camptothecin compounds
|
|
US6613917B1
(en)
|
2000-03-23 |
2003-09-02 |
Allergan, Inc. |
Amines substituted with a dihydronaphthalenyl, chromenyl, or thiochromenyl group, an aryl or heteroaryl group and an alkyl group, having retinoid-like biological activity
|
|
JP2004507456A
(ja)
|
2000-05-11 |
2004-03-11 |
ブリストル−マイヤーズ スクイブ カンパニー |
成長ホルモン分泌促進薬として有用なテトラヒドロイソキノリン類縁体
|
|
EP1283199A4
(en)
|
2000-05-16 |
2003-12-17 |
Takeda Chemical Industries Ltd |
MELANINE CONCENTRATING HORMONE ANTAGONISTS
|
|
DE10024939A1
(de)
|
2000-05-19 |
2001-11-29 |
Bayer Ag |
Neue Diphenylmethanderivate für Arzneimittel
|
|
CA2308994A1
(en)
*
|
2000-05-19 |
2001-11-19 |
Aegera Therapeutics Inc. |
Neuroprotective compounds
|
|
IL136458A0
(en)
|
2000-05-30 |
2001-06-14 |
Peptor Ltd |
Protein kinase inhibitors
|
|
BR0111754A
(pt)
|
2000-06-28 |
2003-04-29 |
Astrazeneca Ab |
Uso de um composto, método para inibir aurora 2 quinase em um animal de sangue quente, composto, e, composição farmacêutica
|
|
CA2413134C
(en)
|
2000-06-30 |
2010-05-11 |
Glaxo Group Limited |
Quinazoline ditosylate salt compounds
|
|
FR2812876B1
(fr)
|
2000-08-08 |
2002-09-27 |
Galderma Res & Dev |
Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar-gamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques
|
|
CA2416527C
(en)
|
2000-08-10 |
2009-12-22 |
Pharmacia Italia S.P.A. |
Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
|
|
AP2001002249A0
(en)
|
2000-08-25 |
2001-09-30 |
Warner Lambert Co |
Process for making N-ARYL-ANTHRANILIC acids and their derivatives.
|
|
BRPI0113757B8
(pt)
|
2000-09-11 |
2017-11-07 |
Chiron Corp |
derivados de quinolinona como inibidores de tirosina quinase
|
|
WO2002036574A1
(en)
|
2000-11-06 |
2002-05-10 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Geldanamycin derivatives useful for the treatment of cancer
|
|
US6455559B1
(en)
|
2001-07-19 |
2002-09-24 |
Pharmacia Italia S.P.A. |
Phenylacetamido-pyrazole derivatives, process for their preparation and their use as antitumor agents
|
|
WO2002049632A1
(en)
|
2000-12-18 |
2002-06-27 |
Institute Of Medicinal Molecular Design. Inc. |
Inhibitors against the production and release of inflammatory cytokines
|
|
BR0116493A
(pt)
|
2000-12-21 |
2003-09-30 |
Vertex Pharma |
Compostos de pirazol úteis como inibidores de proteìna cinase
|
|
NZ526624A
(en)
|
2000-12-22 |
2005-07-29 |
Ortho Mcneil Pharm Inc |
Substituted triazole diamine derivatives as kinase inhibitors
|
|
CA2440809A1
(en)
|
2001-03-01 |
2002-09-12 |
Conforma Therapeutics Corp. |
Methods for treating genetically-defined proliferative disorders with hsp90 inhibitors
|
|
IL159120A0
(en)
|
2001-05-29 |
2004-05-12 |
Schering Ag |
Cdk inhibiting pyrimidines, production thereof and their use as medicaments
|
|
EP1420747A4
(en)
|
2001-08-06 |
2010-06-02 |
Kosan Biosciences Inc |
ANSAMYCIN BENZOQUINONE
|
|
JP2005504086A
(ja)
|
2001-09-24 |
2005-02-10 |
コンフォーマ セラピューティクス コーポレーション |
17−アリルアミノゲルダナマイシン(17−aag)および他のアンサマイシン類を製造する方法
|
|
AU2002366362A1
(en)
|
2001-12-18 |
2003-06-30 |
Bayer Aktiengesellschaft |
2-substituted pyrrolo(2.1-a)isoquinolines against cancer
|
|
KR20040068317A
(ko)
|
2001-12-20 |
2004-07-30 |
오에스아이 파마슈티컬스, 인코포레이티드 |
피리미딘 a₂b 선택성 길항 화합물, 그의 합성 방법 및용도
|
|
JP4399265B2
(ja)
|
2001-12-21 |
2010-01-13 |
ヴァーナリス(ケンブリッジ)リミテッド |
3,4−ジアリールピラゾール、および癌の治療におけるそれらの使用
|
|
SE0104462D0
(sv)
|
2001-12-29 |
2001-12-29 |
Carlbiotech Ltd As |
Peptide purifcation (Peptidrening)
|
|
WO2003061385A1
(en)
|
2002-01-17 |
2003-07-31 |
Ribapharm Inc. |
Tricyclic nucleoside library compounds, synthesis, and use as antiviral agents
|
|
US6927036B2
(en)
|
2002-02-19 |
2005-08-09 |
Xero Port, Inc. |
Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
|
|
EP1497268A4
(en)
|
2002-04-05 |
2006-01-18 |
Nitromed Inc |
NITROGEN OXIDE DISPENSER, COMPOSITIONS AND METHOD OF USE
|
|
AU2003224341A1
(en)
|
2002-04-26 |
2003-11-10 |
Warner-Lambert Company Llc |
Inhibitors of checkpoint kinases (wee1 and chk1)
|
|
WO2003103658A1
(ja)
|
2002-06-05 |
2003-12-18 |
株式会社医薬分子設計研究所 |
免疫関連プロテインキナーゼ阻害剤
|
|
CA2488342A1
(en)
|
2002-06-05 |
2003-12-18 |
Institute Of Medicinal Molecular Design, Inc. |
Therapeutic drug for diabetes
|
|
EA009523B1
(ru)
|
2002-06-05 |
2008-02-28 |
Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. |
Ингибиторы в отношении активации ар-1 и nfat
|
|
AU2003242103A1
(en)
|
2002-06-06 |
2003-12-22 |
Institute Of Medicinal Molecular Design, Inc |
Antiallergic agents
|
|
MY141867A
(en)
|
2002-06-20 |
2010-07-16 |
Vertex Pharma |
Substituted pyrimidines useful as protein kinase inhibitors
|
|
GB0215676D0
(en)
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
|
SE0202133D0
(sv)
|
2002-07-08 |
2002-07-08 |
Astrazeneca Ab |
Novel compounds
|
|
CA2393720C
(en)
|
2002-07-12 |
2010-09-14 |
Eli Lilly And Company |
Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride
|
|
CN100354276C
(zh)
*
|
2002-07-16 |
2007-12-12 |
阿姆拉医疗有限公司 |
生物活性化合物
|
|
US6800655B2
(en)
|
2002-08-20 |
2004-10-05 |
Sri International |
Analogs of indole-3-carbinol metabolites as chemotherapeutic and chemopreventive agents
|
|
JP2006505571A
(ja)
*
|
2002-10-15 |
2006-02-16 |
リゲル ファーマシューテイカルズ、インコーポレイテッド |
置換されたインドール及びhcv阻害剤としてのその使用
|
|
AU2003302589A1
(en)
|
2002-12-02 |
2004-06-23 |
Kyukyu Pharmaceutical Co., Ltd. |
Method for producing orally administrable edible agent of laminate film form and pressure bonding apparatus of the agent.
|
|
TWI228885B
(en)
|
2003-01-23 |
2005-03-01 |
Mediatek Inc |
Method for controlling a mobile communication device to enter a power-saving mode and to recover timing after the mobile communication device leaves the power-saving mode
|
|
KR101166749B1
(ko)
|
2003-02-11 |
2012-07-27 |
베르날리스(캠브리지)리미티드 |
열쇼크 단백질 저해제로서의 이소옥사졸 화합물
|
|
JP2006514088A
(ja)
|
2003-02-20 |
2006-04-27 |
ユニバーシティー オブ コネティカット ヘルス センター |
癌および感染症の治療における熱ショックタンパク質またはα−2−マクログロブリンを含む組成物の使用方法
|
|
JP2006518368A
(ja)
|
2003-02-21 |
2006-08-10 |
ファイザー・インク |
プロテインキナーゼ阻害剤としてのn−ヘテロシクリル置換アミノチアゾール誘導体
|
|
DE50307267D1
(de)
|
2003-02-26 |
2007-06-21 |
Boehringer Ingelheim Pharma |
Dihydropteridinone, verfahren zu deren herstellung und deren verwendung als arzneimittel
|
|
US6887855B2
(en)
|
2003-03-17 |
2005-05-03 |
Pharmion Corporation |
Forms of 5-azacytidine
|
|
US7038038B2
(en)
|
2003-03-17 |
2006-05-02 |
Pharmion Corporation |
Synthesis of 5-azacytidine
|
|
US6943249B2
(en)
|
2003-03-17 |
2005-09-13 |
Ash Stevens, Inc. |
Methods for isolating crystalline Form I of 5-azacytidine
|
|
KR20050119671A
(ko)
|
2003-04-03 |
2005-12-21 |
화이자 인코포레이티드 |
Ag013736을 포함하는 제형
|
|
AU2004234067B2
(en)
|
2003-04-30 |
2008-02-28 |
Novartis Ag |
Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators
|
|
GB0315111D0
(en)
|
2003-06-27 |
2003-07-30 |
Cancer Rec Tech Ltd |
Substituted 5-membered ring compounds and their use
|
|
AU2004251949B2
(en)
|
2003-06-27 |
2009-05-07 |
Kyowa Hakko Kirin Co., Ltd. |
Hsp90 family protein inhibitors
|
|
TWI322806B
(en)
|
2003-06-30 |
2010-04-01 |
Mitsubishi Tanabe Pharma Corp |
Process of preparating 3-acylaminobenzofuran-2-carboxylic acid derivatives
|
|
TWI372050B
(en)
*
|
2003-07-03 |
2012-09-11 |
Astex Therapeutics Ltd |
(morpholin-4-ylmethyl-1h-benzimidazol-2-yl)-1h-pyrazoles
|
|
US20070042997A1
(en)
|
2003-07-16 |
2007-02-22 |
Akiko Itai |
Medicament for treatment of dermal pigmentation
|
|
EP2256106B1
(en)
|
2003-07-22 |
2015-05-06 |
Astex Therapeutics Limited |
3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinases (CDK) and glycogen synthase kinase-3 (GSK-3) modulators
|
|
RU2396250C2
(ru)
|
2003-07-24 |
2010-08-10 |
Лео Фарма А/С |
Новые производные аминобензофенона
|
|
WO2005012296A1
(en)
|
2003-07-28 |
2005-02-10 |
Janssen Pharmaceutica N.V. |
Benzimidazole, benzthiazole and benzoxazole derivatives and their use as lta4h modulators
|
|
DE10335584B4
(de)
|
2003-07-31 |
2006-06-29 |
Philipps-Universität Marburg |
Verfahren zur Herstellung zyklischer Moleküle
|
|
DE10335726A1
(de)
|
2003-08-05 |
2005-03-03 |
Bayer Cropscience Gmbh |
Verwendung von Hydroxyaromaten als Safener
|
|
WO2005016889A1
(en)
|
2003-08-08 |
2005-02-24 |
Virginia Commonwealth University |
Compounds having antiestrogenic and tissue selective estrogenic properties
|
|
EP1670804A2
(en)
|
2003-09-10 |
2006-06-21 |
GPC Biotech AG |
Heterobicyclic compounds as pharmaceutically active agents
|
|
WO2005037825A2
(en)
|
2003-10-14 |
2005-04-28 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Protein kinase inhibitors
|
|
WO2005037214A2
(en)
|
2003-10-14 |
2005-04-28 |
Intermune, Inc. |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
|
|
JP4823914B2
(ja)
|
2003-11-07 |
2011-11-24 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
Fgfr3の阻害および多発性骨髄腫の治療
|
|
CN1902171A
(zh)
|
2003-11-10 |
2007-01-24 |
舍林股份公司 |
用作ccr-5拮抗剂的苄醚胺化合物
|
|
SI1686997T1
(sl)
|
2003-11-18 |
2009-08-31 |
Novartis Ag |
Inhibitorji mutantne oblike KIT
|
|
US7282493B2
(en)
|
2003-12-23 |
2007-10-16 |
Infinity Pharmaceuticals, Inc. |
Analogs of benzoquinone-containing ansamycins and methods of use thereof
|
|
EP1704856A4
(en)
|
2003-12-26 |
2009-08-19 |
Kyowa Hakko Kirin Co Ltd |
PROTEIN INHIBITOR OF THE HSP90 FAMILY
|
|
US7652146B2
(en)
|
2004-02-06 |
2010-01-26 |
Bristol-Myers Squibb Company |
Process for preparing 2-aminothiazole-5-carboxamides useful as kinase inhibitors
|
|
TWI338004B
(en)
|
2004-02-06 |
2011-03-01 |
Bristol Myers Squibb Co |
Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
|
|
US20050256097A1
(en)
|
2004-05-11 |
2005-11-17 |
Kosan Biosciences, Inc. |
Pharmaceutical solution formulations containing 17-AAG
|
|
KR101792651B1
(ko)
|
2004-05-14 |
2017-11-20 |
밀레니엄 파머슈티컬스 인코퍼레이티드 |
아우로라 키나아제의 억제에 의해 유사분열 진행을 억제하기 위한 화합물 및 그 화합물을 포함하는 약학적 조성물
|
|
US7351709B2
(en)
|
2004-06-09 |
2008-04-01 |
Wyeth |
Estrogen receptor ligands
|
|
US20060014949A1
(en)
|
2004-07-13 |
2006-01-19 |
Supergen Inc. |
Compositions and formulations of decitabine polymorphs and methods of use thereof
|
|
NZ553267A
(en)
|
2004-07-27 |
2010-09-30 |
Sgx Pharmaceuticals Inc |
Pyrrolo-pyridine kinase modulators
|
|
US7759485B2
(en)
|
2004-08-14 |
2010-07-20 |
Boehringer Ingelheim International Gmbh |
Process for the manufacture of dihydropteridinones
|
|
US20060035903A1
(en)
|
2004-08-14 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Storage stable perfusion solution for dihydropteridinones
|
|
US7728134B2
(en)
|
2004-08-14 |
2010-06-01 |
Boehringer Ingelheim International Gmbh |
Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
|
|
BRPI0514504A
(pt)
|
2004-08-20 |
2008-06-10 |
Univ Michigan |
pequenas moléculas inibidoras de membros da famìlia bcl-2 anti-apoptóticos e os usos das mesmas
|
|
US20060069060A1
(en)
|
2004-09-27 |
2006-03-30 |
Sanjeev Redkar |
Salts of decitabine
|
|
US20060067953A1
(en)
|
2004-09-29 |
2006-03-30 |
Conforma Therapeutics Corporation |
Oral pharmaceutical formulations and methods for producing and using same
|
|
DE102004049078A1
(de)
|
2004-10-08 |
2006-04-13 |
Merck Patent Gmbh |
Phenylpyrazole
|
|
US7208630B2
(en)
|
2004-10-27 |
2007-04-24 |
University Of Kansas |
Heat shock protein 90 inhibitors
|
|
WO2006050333A2
(en)
|
2004-11-02 |
2006-05-11 |
The Regents Of The University Of California |
Methods and compositions for modulating apoptosis
|
|
CN101094836A
(zh)
|
2004-11-02 |
2007-12-26 |
辉瑞大药厂 |
制备吲唑化合物的方法
|
|
BRPI0517921A
(pt)
|
2004-11-02 |
2008-10-21 |
Pfizer |
métodos para preparar compostos de indazol
|
|
US7781485B2
(en)
|
2004-11-09 |
2010-08-24 |
Kyowa Hakko Kirin Co., Ltd. |
Hsp90 family protein inhibitors
|
|
ES2594874T3
(es)
|
2004-11-18 |
2016-12-23 |
Synta Pharmaceuticals Corp. |
Compuestos de triazol que modulan la actividad de HSP90
|
|
MX2007008008A
(es)
*
|
2004-12-30 |
2007-11-12 |
Astex Therapeutics Ltd |
Compuestos de pirazol que modulan la actividad de las cinasas cdk, gsk y aurora.
|
|
AR054425A1
(es)
|
2005-01-21 |
2007-06-27 |
Astex Therapeutics Ltd |
Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico.
|
|
WO2006082001A1
(en)
|
2005-02-07 |
2006-08-10 |
F.Hoffmann-La Roche Ag |
Heterocyclic substituted phenyl methanones as inhibitors of the glycine transporter 1
|
|
WO2006088954A1
(en)
|
2005-02-15 |
2006-08-24 |
Janssen Pharmaceutica, N.V. |
Dihydroindolyl methanones as alpha 1a/1d adrenoreceptor modulators for the treatment of benign prostatic hypertrophy and lower urinary tract symptoms
|
|
JPWO2006088193A1
(ja)
|
2005-02-21 |
2008-07-03 |
協和醗酵工業株式会社 |
抗腫瘍剤
|
|
CN101193862B
(zh)
|
2005-04-13 |
2013-08-21 |
阿斯特克斯治疗有限公司 |
羟基苯甲酰胺衍生物和其作为hsp90抑制剂的用途
|
|
JP2008540395A
(ja)
|
2005-05-03 |
2008-11-20 |
ファイザー・インク |
アミドレソルシノール化合物
|
|
SI1881823T1
(sl)
|
2005-05-17 |
2015-04-30 |
Sarcode Bioscience Inc. |
Sestavki in postopki za zdravljenje bolezni oäśesa
|
|
WO2007050124A1
(en)
|
2005-05-19 |
2007-05-03 |
Xenon Pharmaceuticals Inc. |
Fused piperidine derivatives and their uses as therapeutic agents
|
|
US7425633B2
(en)
|
2005-08-26 |
2008-09-16 |
National Health Research Institutes |
Pyrrolidine compounds
|
|
JP5474354B2
(ja)
|
2005-12-30 |
2014-04-16 |
アステックス、セラピューティックス、リミテッド |
医薬化合物
|
|
US7785275B2
(en)
*
|
2006-01-31 |
2010-08-31 |
Cook Incorporated |
Wire guide having distal coupling tip
|
|
US7754725B2
(en)
|
2006-03-01 |
2010-07-13 |
Astex Therapeutics Ltd. |
Dihydroxyphenyl isoindolymethanones
|
|
US8883790B2
(en)
|
2006-10-12 |
2014-11-11 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
|
US8916552B2
(en)
|
2006-10-12 |
2014-12-23 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
|
GB0620259D0
(en)
|
2006-10-12 |
2006-11-22 |
Astex Therapeutics Ltd |
Pharmaceutical compounds
|
|
JP5721949B2
(ja)
|
2006-10-12 |
2015-05-20 |
アステックス、セラピューティックス、リミテッドAstex Therapeutics Limited |
複合薬剤
|
|
JP5410285B2
(ja)
|
2006-10-12 |
2014-02-05 |
アステックス、セラピューティックス、リミテッド |
医薬化合物
|
|
JP5518478B2
(ja)
|
2006-10-12 |
2014-06-11 |
アステックス、セラピューティックス、リミテッド |
医薬化合物
|
|
WO2008053319A1
(en)
|
2006-10-30 |
2008-05-08 |
Pfizer Products Inc. |
Amide resorcinol compounds
|
|
ES2409854T3
(es)
*
|
2008-06-11 |
2013-06-28 |
Morinaga Milk Industry Co., Ltd. |
Procedimiento para producir leche fermentada
|