AU2001243158A1 - Inhibitors of prenyl-protein transferase - Google Patents

Inhibitors of prenyl-protein transferase

Info

Publication number
AU2001243158A1
AU2001243158A1 AU2001243158A AU4315801A AU2001243158A1 AU 2001243158 A1 AU2001243158 A1 AU 2001243158A1 AU 2001243158 A AU2001243158 A AU 2001243158A AU 4315801 A AU4315801 A AU 4315801A AU 2001243158 A1 AU2001243158 A1 AU 2001243158A1
Authority
AU
Australia
Prior art keywords
prenyl
inhibitors
protein transferase
transferase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001243158A
Inventor
Jeffrey M Bergman
Christopher J. Dinsmore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2001243158A1 publication Critical patent/AU2001243158A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
AU2001243158A 2000-02-18 2001-02-15 Inhibitors of prenyl-protein transferase Abandoned AU2001243158A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18344900P 2000-02-18 2000-02-18
US60183449 2000-02-18
PCT/US2001/004868 WO2001060369A1 (en) 2000-02-18 2001-02-15 Inhibitors of prenyl-protein transferase

Publications (1)

Publication Number Publication Date
AU2001243158A1 true AU2001243158A1 (en) 2001-08-27

Family

ID=22672832

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001243158A Abandoned AU2001243158A1 (en) 2000-02-18 2001-02-15 Inhibitors of prenyl-protein transferase

Country Status (3)

Country Link
US (1) US20020052363A1 (en)
AU (1) AU2001243158A1 (en)
WO (1) WO2001060369A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003248549B2 (en) * 2002-05-24 2010-04-08 Millennium Pharmaceuticals, Inc. CCR9 inhibitors and methods of use thereof
EP1798223B2 (en) 2002-11-18 2014-07-30 ChemoCentryx, Inc. Aryl sulfonamides
AU2005286846A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
TW200626572A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
EP1804799B1 (en) 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
BRPI0515505A (en) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc heterocyclic derivatives and their use as stearoyl coat desaturase inhibitors
AR051094A1 (en) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc HETEROCICLIC DERIVATIVES AND THEIR USE AS INHIBITORS OF ESTEAROIL-COA DESATURASA
AR051202A1 (en) 2004-09-20 2006-12-27 Xenon Pharmaceuticals Inc HETEROCICLIC DERIVATIVES AND THEIR USE AS INHIBITORS OF ESTEAROIL-COA DESATURASA
US9040558B2 (en) 2004-12-31 2015-05-26 Dr. Reddy's Laboratories Ltd. Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
US8604055B2 (en) 2004-12-31 2013-12-10 Dr. Reddy's Laboratories Ltd. Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
EP2354126B1 (en) * 2005-01-14 2013-09-25 ChemoCentryx, Inc. Heteroaryl sulfonamides and CCR2
US7622583B2 (en) * 2005-01-14 2009-11-24 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2
MX2007012659A (en) 2005-04-13 2008-01-11 Astex Therapeutics Ltd Hydroxybenzamide derivatives and their use as inhibitors of hsp90.
EP2540296A1 (en) 2005-06-03 2013-01-02 Xenon Pharmaceuticals Inc. Arminothiazole derivatives as human stearoyl-coa desaturase inhibitors
US7754725B2 (en) 2006-03-01 2010-07-13 Astex Therapeutics Ltd. Dihydroxyphenyl isoindolymethanones
US8519135B2 (en) * 2006-07-14 2013-08-27 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2/CCR9
EP2086970B1 (en) 2006-08-24 2014-02-26 Novartis AG 2-(pyrazin-2-yl)-thiazole and 2-(1h pyrazol-3-yl)-thiazole derivatives as well as related compounds as stearoyl-coa desaturase (scd) inhibitors for the treatment of metabolic, cardiovascular and other disorders
GB0620259D0 (en) 2006-10-12 2006-11-22 Astex Therapeutics Ltd Pharmaceutical compounds
EP2073804B1 (en) 2006-10-12 2017-09-13 Astex Therapeutics Limited Hydroxy-substituted benzoic acid amide compounds for use in the treatment of pain
EP2081891A2 (en) 2006-10-12 2009-07-29 Astex Therapeutics Limited Pharmaceutical compounds having hsp90 inhibitory or modulating activity
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
US8277807B2 (en) 2006-10-12 2012-10-02 Astex Therapeutics Limited Pharmaceutical combinations
EP2175859B1 (en) 2007-07-12 2012-03-07 ChemoCentryx, Inc. Fused heteroaryl pyridyl and phenyl benzenesulfonamides as ccr2 modulators for the treament of inflammation
GB0806527D0 (en) 2008-04-11 2008-05-14 Astex Therapeutics Ltd Pharmaceutical compounds
CA2845284C (en) 2011-08-18 2018-03-06 Dr. Reddy's Laboratories Ltd. Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (cetp) inhibitors
CA2850022C (en) 2011-09-27 2018-05-01 Dr. Reddy's Laboratories, Ltd. 5 - benzylaminomethyl - 6 - aminopyrazolo [3,4-b] pyridine derivatives as cholesteryl ester-transfer protein (cetp) inhibitors useful for the treatment of atherosclerosis
CA3044621A1 (en) 2016-11-23 2018-05-31 Chemocentryx, Inc. Method of treating focal segmental glomerulosclerosis
KR20200070299A (en) 2017-10-11 2020-06-17 케모센트릭스, 인크. Treatment of local segmental glomerulosclerosis with CCR2 antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists

Also Published As

Publication number Publication date
WO2001060369A1 (en) 2001-08-23
US20020052363A1 (en) 2002-05-02

Similar Documents

Publication Publication Date Title
AU2001243158A1 (en) Inhibitors of prenyl-protein transferase
EP1324985A4 (en) Inhibitors of prenyl-protein transferase
EP1087770A4 (en) Inhibitors of prenyl-protein transferase
EP1165082A4 (en) Inhibitors of prenyl-protein transferase
AU2001241927A1 (en) Inhibitors of p38-alpha kinase
AU2002213485A1 (en) Inhibitors of protein kinases
AU2001237041A1 (en) Kinase inhibitors
EP1165084A4 (en) Inhibitors of prenyl-protein transferases
AU2001238217A1 (en) Inhibitors of prenyl-protein transferase
EP1091736A4 (en) Inhibitors of prenyl-protein transferase
AU2001247197A1 (en) Inhibitors of prenyl-protein transferase
AU7354900A (en) Inhibitors of prenyl-protein transferase
AU2477400A (en) Inhibitors of prenyl-protein transferase
AU2001227757A1 (en) Inhibitors of prenyl-protein transferase
AU2001238424A1 (en) Inhibitors of prenyl-protein transferase
AU2274101A (en) Inhibitors of prenyl-protein transferase
EP1158982A4 (en) Inhibitors of prenyl-protein transferase
AU2002237657A1 (en) Indole-type inhibitors of p38 kinase
AU2001230864A1 (en) Inhibitors of prenyl-protein transferase
AU2001229320A1 (en) Inhibitors of prenyl-protein transferase
AU2001227756A1 (en) Inhibitors of prenyl-protein transferase
AU2002214038A1 (en) Inhibitors of transglutaminases
AU2002254375A1 (en) Inhibitors of prenyl-protein transferase
AU2001251445A1 (en) Inhibitors of prenyl-protein transferase
AU2478500A (en) Inhibitors of prenyl-protein transferase