AU2001238217A1 - Inhibitors of prenyl-protein transferase - Google Patents

Inhibitors of prenyl-protein transferase

Info

Publication number
AU2001238217A1
AU2001238217A1 AU2001238217A AU3821701A AU2001238217A1 AU 2001238217 A1 AU2001238217 A1 AU 2001238217A1 AU 2001238217 A AU2001238217 A AU 2001238217A AU 3821701 A AU3821701 A AU 3821701A AU 2001238217 A1 AU2001238217 A1 AU 2001238217A1
Authority
AU
Australia
Prior art keywords
prenyl
inhibitors
protein transferase
transferase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001238217A
Inventor
Jeffrey M Bergman
Christopher J. Dinsmore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2001238217A1 publication Critical patent/AU2001238217A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
AU2001238217A 2000-02-18 2001-02-14 Inhibitors of prenyl-protein transferase Abandoned AU2001238217A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18365000P 2000-02-18 2000-02-18
US60183650 2000-02-18
PCT/US2001/004639 WO2001060815A1 (en) 2000-02-18 2001-02-14 Inhibitors of prenyl-protein transferase

Publications (1)

Publication Number Publication Date
AU2001238217A1 true AU2001238217A1 (en) 2001-08-27

Family

ID=22673732

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001238217A Abandoned AU2001238217A1 (en) 2000-02-18 2001-02-14 Inhibitors of prenyl-protein transferase

Country Status (3)

Country Link
US (1) US20020052380A1 (en)
AU (1) AU2001238217A1 (en)
WO (1) WO2001060815A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050272722A1 (en) * 2004-03-18 2005-12-08 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies
US20050288298A1 (en) * 2004-03-18 2005-12-29 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies
US20070293539A1 (en) * 2004-03-18 2007-12-20 Lansbury Peter T Methods for the treatment of synucleinopathies
WO2005089518A2 (en) * 2004-03-18 2005-09-29 The Brigham And Women's Hospital, Inc. Uch-l1 expression and cancer therapy
JP2007538004A (en) * 2004-03-18 2007-12-27 ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド How to treat synucleinopathy
WO2005089502A2 (en) * 2004-03-18 2005-09-29 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies
GB0611907D0 (en) * 2006-06-15 2006-07-26 Glaxo Group Ltd Compounds
US20060194821A1 (en) * 2005-02-18 2006-08-31 The Brigham And Women's Hospital, Inc. Compounds inhibiting the aggregation of superoxide dismutase-1
JO2747B1 (en) * 2005-07-26 2014-03-15 جلاكسو جروب ليمتد Compounds
KR20090031688A (en) * 2006-06-28 2009-03-27 글락소 그룹 리미티드 Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases
WO2009151683A2 (en) * 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
US20100331363A1 (en) * 2008-11-13 2010-12-30 Link Medicine Corporation Treatment of mitochondrial disorders using a farnesyl transferase inhibitor
US20110060005A1 (en) * 2008-11-13 2011-03-10 Link Medicine Corporation Treatment of mitochondrial disorders using a farnesyl transferase inhibitor
WO2010057006A1 (en) * 2008-11-13 2010-05-20 Link Medicine Corporation Azaquinolinone derivatives and uses thereof
WO2011103091A1 (en) 2010-02-18 2011-08-25 Transtech Pharma, Inc. Phenyl-heteroaryl derivatives and methods of use thereof
WO2011153359A1 (en) 2010-06-04 2011-12-08 Albany Molecular Research, Inc. Glycine transporter-1 inhibitors, methods of making them, and uses thereof
WO2015070367A1 (en) * 2013-11-12 2015-05-21 Merck Sharp & Dohme Corp. Piperidine or piperazine linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
CN104297414A (en) * 2014-10-18 2015-01-21 中山鼎晟生物科技有限公司 Method for detecting chloramphenicol in anti-acne cream

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1014984A1 (en) * 1997-08-27 2000-07-05 Merck & Co., Inc. Inhibitors of prenyl-protein transferase

Also Published As

Publication number Publication date
WO2001060815A1 (en) 2001-08-23
US20020052380A1 (en) 2002-05-02

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